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Search term: YOL061W

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name PRS5
SGD link S000005422
Alternative ID YOL061W
Description 5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase, synthesizes PRPP, which is required for nucleotide, histidine, and tryptophan biosynthesis; one of five related enzymes, which are active as heteromultimeric complexes
Synonyms YOL061W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG1448 ACDHYP-

KOGs classification KOGs description
METABOLISMMETABOLISM Ribose-phosphate pyrophosphokinase

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At1g10700 GI:15220191
Arabidopsis thaliana (Ath) At1g32380 GI:15223189
Arabidopsis thaliana (Ath) At2g35390 GI:15226977
Arabidopsis thaliana (Ath) At2g42910 GI:15228027
Arabidopsis thaliana (Ath) At2g44530 GI:15224894
Caenorhabditis elegans (Cel) CE00745
(WBGene00020107)		 GI:17554702 Q21994
Caenorhabditis elegans (Cel) CE27199 GI:17554700
Caenorhabditis elegans (Cel) CE29454 GI:17554704 Q21994
Drosophila melanogaster (Dme) 7294893 GI:7294893
Drosophila melanogaster (Dme) 7294894 GI:7294894
Homo sapiens (Hsa) Hs20539448 GI:20539448
Homo sapiens (Hsa) Hs20542182 GI:20542182
Homo sapiens (Hsa) Hs4506127
(PRPS1)		 GI:4506127 Q15244
Homo sapiens (Hsa) Hs4506129 GI:4506129 P11908
Saccharomyces cerevisiae (Sce) YBL068w
(S000000164)		 GI:6319403
Saccharomyces cerevisiae (Sce) YER099c
(S000000901)		 GI:6320946 P38620
Saccharomyces cerevisiae (Sce) YHL011c
(S000001003)		 GI:6321776 P38689
Saccharomyces cerevisiae (Sce) YKL181w
(S000001664)		 GI:6322667 P32895
Saccharomyces cerevisiae (Sce) YOL061w
(S000005422)		 GI:6324511 Q12265
Schizosaccharomyces pombe (Spo) SPAC4A8.14 GI:19114738 P41831
Schizosaccharomyces pombe (Spo) SPBC3D6.06c GI:19112310 P87171
Schizosaccharomyces pombe (Spo) SPCC1620.06c GI:19075964 O94413


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SpoSPAC4A8.14
GO:0005737 cytoplasm C
IDA
AthAt2g42910
SceS000000901
S000005422
S000000164
S000001003
S000001664
ISS
SpoSPAC4A8.14
SPBC3D6.06c
SPCC1620.06c
GO:0005829 cytosol C
EXP
HsaPRPS1
IDA
SpoSPCC1620.06c
SPAC4A8.14
GO:0005886 plasma membrane C
IDA
AthAt2g42910
GO:0004749 ribose phosphate diphosphokinase
activity		 F
EXP
HsaPRPS1
IDA
HsaPRPS1
IGI
SceS000000901
S000000164
S000001003
S000001664
S000005422
IMP
HsaPRPS1
ISS
AthAt1g32380
At2g35390
At2g44530
At2g42910
At1g10700
SpoSPAC4A8.14
SPBC3D6.06c
SPCC1620.06c
GO:0005524 ATP binding F
IDA
HsaPRPS1
GO:0042803 protein homodimerization activity F
IPI
HsaPRPS1
GO:0000105 histidine biosynthetic process P
ISS
SpoSPAC4A8.14
SPBC3D6.06c
SPCC1620.06c
GO:0000162 tryptophan biosynthetic process P
ISS
SpoSPAC4A8.14
SPBC3D6.06c
SPCC1620.06c
GO:0006015 5-phosphoribose 1-diphosphate biosynthetic
process		 P
IGI
SceS000001664
S000000901
S000000164
S000001003
S000005422
IMP
SceS000000164
S000000901
S000005422
S000001003
S000001664
GO:0006144 purine base metabolic process P
IMP
HsaPRPS1
GO:0006164 purine nucleotide biosynthetic
process		 P
IMP
HsaPRPS1
GO:0006166 purine ribonucleoside salvage P
ISS
SpoSPAC4A8.14
SPBC3D6.06c
SPCC1620.06c
GO:0006189 'de novo' IMP biosynthetic process P
ISS
SpoSPAC4A8.14
SPBC3D6.06c
SPCC1620.06c
GO:0006207 'de novo' pyrimidine base biosynthetic
process		 P
ISS
SpoSPBC3D6.06c
SPAC4A8.14
SPCC1620.06c
GO:0006221 pyrimidine nucleotide biosynthetic
process		 P
NAS
HsaPRPS1
GO:0007399 nervous system development P
IMP
HsaPRPS1
GO:0008361 regulation of cell size P
IMP
SceS000001003
GO:0009116 nucleoside metabolic process P
RCA
SceS000000164
S000000901
S000001003
S000005422
GO:0009117 nucleotide metabolic process P
RCA
SceS000000901
S000001003
S000000164
S000001664
S000005422
GO:0009165 nucleotide biosynthetic process P
ISS
AthAt2g44530
At1g10700
At2g35390
At2g42910
At1g32380
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00020107
GO:0018193 peptidyl-amino acid modification P
RCA
SceS000000164
GO:0031505 fungal-type cell wall organization P
IPI
SceS000000164
S000000901
S000001003
S000001664
S000005422
GO:0034418 urate biosynthetic process P
IMP
HsaPRPS1
GO:0043094 cellular metabolic compound salvage P
RCA
SceS000001003
S000005422
S000001664
GO:0046101 hypoxanthine biosynthetic process P
IMP
HsaPRPS1

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
68920

Species Gene ID NCBI link UniProt link
Schizosaccharomyces pombe (Spo) SPBC3D6.06c GI:19112310 P87171
Saccharomyces cerevisiae (Sce) PRS5
(S000005422)		 GI:6324511 Q12265
Kluyveromyces lactis (Kla) KLLA0C03916g GI:50304831
Eremothecium gossypii (Ego) AGOS_ADR314C GI:45188187
Magnaporthe grisea (Mgr) MGG_06678 GI:145606080
Neurospora crassa (Ncr) NCU01786.1 GI:32415491


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005737 cytoplasm C
IDA
SceS000005422
ISS
SpoSPBC3D6.06c
GO:0004749 ribose phosphate diphosphokinase
activity		 F
IGI
SceS000005422
ISS
SpoSPBC3D6.06c
GO:0000105 histidine biosynthetic process P
ISS
SpoSPBC3D6.06c
GO:0000162 tryptophan biosynthetic process P
ISS
SpoSPBC3D6.06c
GO:0006015 5-phosphoribose 1-diphosphate biosynthetic
process		 P
IGI
SceS000005422
IMP
SceS000005422
GO:0006166 purine ribonucleoside salvage P
ISS
SpoSPBC3D6.06c
GO:0006189 'de novo' IMP biosynthetic process P
ISS
SpoSPBC3D6.06c
GO:0006207 'de novo' pyrimidine base biosynthetic
process		 P
ISS
SpoSPBC3D6.06c
GO:0009116 nucleoside metabolic process P
RCA
SceS000005422
GO:0009117 nucleotide metabolic process P
RCA
SceS000005422
GO:0031505 fungal-type cell wall organization P
IPI
SceS000005422
GO:0043094 cellular metabolic compound salvage P
RCA
SceS000005422

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_13265

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Ashbya gossypii (Ago) ago2055 ADR314C
Candida glabrata (Cgl) cgl639 CAGL0C05181g
Debaryomyces hansenii (Dha) dha1919 DEHA0C11022g
Kluyveromyces lactis (Kla) kla1370 KLLA0C03916g
Neurospora crassa (Ncr) ncr1232 NCU01270.2
Neurospora crassa (Ncr) ncr1738 NCU01786.2
Saccharomyces cerevisiae (Sce) sce5613 YOL061W
(S000005422)
Schizosaccharomyces pombe (Spo) spo2079 SPBC3D6.06c P87171
Yarrowia lipolytica (Yli) yli777 YALI0B00836g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005737 cytoplasm C
IDA
SceS000005422
ISS
SpoSPBC3D6.06c
GO:0004749 ribose phosphate diphosphokinase
activity		 F
IGI
SceS000005422
ISS
SpoSPBC3D6.06c
GO:0000105 histidine biosynthetic process P
ISS
SpoSPBC3D6.06c
GO:0000162 tryptophan biosynthetic process P
ISS
SpoSPBC3D6.06c
GO:0006015 5-phosphoribose 1-diphosphate biosynthetic
process		 P
IGI
SceS000005422
IMP
SceS000005422
GO:0006166 purine ribonucleoside salvage P
ISS
SpoSPBC3D6.06c
GO:0006189 'de novo' IMP biosynthetic process P
ISS
SpoSPBC3D6.06c
GO:0006207 'de novo' pyrimidine base biosynthetic
process		 P
ISS
SpoSPBC3D6.06c
GO:0009116 nucleoside metabolic process P
RCA
SceS000005422
GO:0009117 nucleotide metabolic process P
RCA
SceS000005422
GO:0031505 fungal-type cell wall organization P
IPI
SceS000005422
GO:0043094 cellular metabolic compound salvage P
RCA
SceS000005422

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPCC1620.06c
(O94413)		 YOL061W
(S000005422)
SPBC3D6.06c
(P87171)		 YOL061W
(S000005422)
SPAC4A8.14
(P41831)		 YOL061W
(S000005422)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SpoSPAC4A8.14
GO:0005737 cytoplasm C
IDA
SceS000005422
ISS
SpoSPAC4A8.14
SPBC3D6.06c
SPCC1620.06c
GO:0005829 cytosol C
IDA
SpoSPCC1620.06c
SPAC4A8.14
GO:0004749 ribose phosphate diphosphokinase
activity		 F
IGI
SceS000005422
ISS
SpoSPAC4A8.14
SPBC3D6.06c
SPCC1620.06c
GO:0000105 histidine biosynthetic process P
ISS
SpoSPAC4A8.14
SPBC3D6.06c
SPCC1620.06c
GO:0000162 tryptophan biosynthetic process P
ISS
SpoSPAC4A8.14
SPBC3D6.06c
SPCC1620.06c
GO:0006015 5-phosphoribose 1-diphosphate biosynthetic
process		 P
IGI
SceS000005422
IMP
SceS000005422
GO:0006166 purine ribonucleoside salvage P
ISS
SpoSPAC4A8.14
SPBC3D6.06c
SPCC1620.06c
GO:0006189 'de novo' IMP biosynthetic process P
ISS
SpoSPAC4A8.14
SPBC3D6.06c
SPCC1620.06c
GO:0006207 'de novo' pyrimidine base biosynthetic
process		 P
ISS
SpoSPBC3D6.06c
SPAC4A8.14
SPCC1620.06c
GO:0009116 nucleoside metabolic process P
RCA
SceS000005422
GO:0009117 nucleotide metabolic process P
RCA
SceS000005422
GO:0031505 fungal-type cell wall organization P
IPI
SceS000005422
GO:0043094 cellular metabolic compound salvage P
RCA
SceS000005422

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GO info in one table:

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