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Search term: YOL066C

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name RIB2
SGD link S000005427
Alternative ID YOL066C
Description Bifunctional enzyme with DRAP deaminase and tRNA:pseudouridine synthase activity; the deaminase catalyzes the third step in riboflavin biosynthesis and the synthase catalyzes formation of pseudouridine at position 32 in cytoplasmic tRNAs
Synonyms YOL066C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
116536

Species Gene ID NCBI link UniProt link
Drosophila melanogaster (Dme) RluA-2
(FBgn0032256)		 GI:19921090
Schizosaccharomyces pombe (Spo) SPAC18B11.02c GI:19113793 Q09709
Saccharomyces cerevisiae (Sce) RIB2
(S000005427)		 GI:6324506 Q12362
Kluyveromyces lactis (Kla) KLLA0F24794g GI:50312303
Eremothecium gossypii (Ego) AGOS_AEL091C GI:45190516
Magnaporthe grisea (Mgr) MGG_08117 GI:145612127
Neurospora crassa (Ncr) NCU03846.1 GI:32405104
Arabidopsis thaliana (Ath) AT5G51140 GI:15241389
Oryza sativa (Osa) Os02g0512300 GI:115446323


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
AthAT5G51140
GO:0005634 nucleus C
ISS
SpoSPAC18B11.02c
GO:0005737 cytoplasm C
IDA
SceS000005427
ISM
SceS000005427
ISS
SpoSPAC18B11.02c
GO:0005739 mitochondrion C
ISS
SpoSPAC18B11.02c
GO:0005829 cytosol C
IDA
SpoSPAC18B11.02c
GO:0009982 pseudouridine synthase activity F
IDA
SceS000005427
IMP
SceS000005427
ISS
AthAT5G51140
SceS000005427
SpoSPAC18B11.02c
TAS
AthAT5G51140
GO:0043723 2,5-diamino-6-ribitylamino-4(3H)-pyrimidinone
5'-phosphate deaminase activity		 F
IMP
SceS000005427
ISS
DmeFBgn0032256
GO:0009231 riboflavin biosynthetic process P
IMP
SceS000005427
GO:0031119 tRNA pseudouridine synthesis P
IDA
SceS000005427
IMP
SceS000005427
ISS
SpoSPAC18B11.02c

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_495

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga11903 ENSANGP00000004675
Anopheles gambiae (Aga) aga11902 ENSANGP00000026660
Ashbya gossypii (Ago) ago2415 AEL091C
Ashbya gossypii (Ago) ago4616 AGR305W
Arabidopsis thaliana (Ath) ath27050 At5g51140.1
Caenorhabditis elegans (Cel) cel12160 K07E8.7
(CE11898;
WBGene00019498)
Candida glabrata (Cgl) cgl644 CAGL0C05291g
Candida glabrata (Cgl) cgl2900 CAGL0I08789g
Candida glabrata (Cgl) cgl3584 CAGL0K01485g
Cryptococcus neoformans (Cne) cne621 163.m06218
Dictyostelium discoideum (Ddi) ddi4595 DDB0204013
Debaryomyces hansenii (Dha) dha3771 DEHA0E11968g
Drosophila melanogaster (Dme) dme1846 CG31719-PA
(FBgn0051719)
Drosophila melanogaster (Dme) dme1847 CG31719-PB
(FBgn0051719)
Drosophila melanogaster (Dme) dme1848 CG31719-PC
(FBgn0051719)
Drosophila melanogaster (Dme) dme1849 CG6187-PA
(FBgn0032256)
Danio rerio (Dre) dre8308 ENSDARP00000017818
Danio rerio (Dre) dre8309 ENSDARP00000020807
Escherichia coli (Eco) eco1050 16129049
Encephalitozoon cuniculi (Ecu) ecu1169 19173607
Takifugu rubripes (Fru) fru20380 SINFRUP00000151729
Takifugu rubripes (Fru) fru20381 SINFRUP00000170447
Homo sapiens (Hsa) hsa10445 ENSP00000323288
(RPUSD2)		 Q8IZ73
Homo sapiens (Hsa) hsa10446 ENSP00000338842
Kluyveromyces lactis (Kla) kla4734 KLLA0F14553g
Kluyveromyces lactis (Kla) kla5184 KLLA0F24794g
Mus musculus (Mmu) mmu15270 ENSMUSP00000028796
(MGI:1918066)		 Q149F1
Neurospora crassa (Ncr) ncr3736 NCU03846.2
Oryza sativa (Osa) osa29173 4264.m00203
Oryza sativa (Osa) osa37455 4866.m00079
Oryza sativa (Osa) osa38681 4901.m00108
Plasmodium falciparum (Pfa) pfa4604 PFI0685w
Rattus norvegicus (Rno) rno19465 ENSRNOP00000014129
(RGD:1306147)
Saccharomyces cerevisiae (Sce) sce805 YDL036C
(S000002194)
Saccharomyces cerevisiae (Sce) sce2547 YGR169C
(S000003401)
Saccharomyces cerevisiae (Sce) sce5618 YOL066C
(S000005427)
Schizosaccharomyces pombe (Spo) spo2670 SPAC18B11.02c Q09709
Yarrowia lipolytica (Yli) yli798 YALI0B01276g
Yarrowia lipolytica (Yli) yli5857 YALI0F12199g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
AthAT5G51140
MmuMGI:1918066
GO:0005634 nucleus C
IDA
SceS000002194
ISS
SpoSPAC18B11.02c
GO:0005737 cytoplasm C
IDA
SceS000005427
S000002194
S000003401
ISM
SceS000005427
ISS
SpoSPAC18B11.02c
GO:0005739 mitochondrion C
IDA
SceS000003401
IMP
SceS000002194
ISM
SceS000002194
ISS
SpoSPAC18B11.02c
GO:0005829 cytosol C
IDA
SpoSPAC18B11.02c
GO:0020011 apicoplast C
ISS
PfaPFI0685w
GO:0003674 molecular_function F
ND
MmuMGI:1918066
GO:0008835 diaminohydroxyphosphoribosylaminopyrimidine
deaminase activity		 F
ISS
DmeFBgn0051719
GO:0009982 pseudouridine synthase activity F
IDA
SceS000005427
S000002194
S000003401
IMP
SceS000005427
S000002194
S000003401
ISS
AthAT5G51140
SceS000005427
SpoSPAC18B11.02c
TAS
AthAT5G51140
GO:0043723 2,5-diamino-6-ribitylamino-4(3H)-pyrimidinone
5'-phosphate deaminase activity		 F
IMP
SceS000005427
ISS
DmeFBgn0032256
GO:0001522 pseudouridine synthesis P
RCA
SceS000002194
GO:0008150 biological_process P
ND
MmuMGI:1918066
GO:0009231 riboflavin biosynthetic process P
IMP
SceS000005427
ISS
DmeFBgn0051719
GO:0031119 tRNA pseudouridine synthesis P
IDA
SceS000005427
S000003401
S000002194
IMP
SceS000005427
S000002194
S000003401
ISS
SpoSPAC18B11.02c

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPCC4G3.16
(P87241)		 YOL066C
(S000005427)
SPAC18B11.02c
(Q09709)		 YOL066C
(S000005427)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SpoSPCC4G3.16
ISS
SpoSPAC18B11.02c
SPCC4G3.16
GO:0005737 cytoplasm C
IDA
SceS000005427
ISM
SceS000005427
ISS
SpoSPAC18B11.02c
SPCC4G3.16
GO:0005739 mitochondrion C
ISS
SpoSPAC18B11.02c
SPCC4G3.16
GO:0005829 cytosol C
IDA
SpoSPAC18B11.02c
SPCC4G3.16
GO:0009982 pseudouridine synthase activity F
IDA
SceS000005427
IMP
SceS000005427
ISS
SceS000005427
SpoSPAC18B11.02c
SPCC4G3.16
GO:0043723 2,5-diamino-6-ribitylamino-4(3H)-pyrimidinone
5'-phosphate deaminase activity		 F
IMP
SceS000005427
GO:0009231 riboflavin biosynthetic process P
IMP
SceS000005427
GO:0031119 tRNA pseudouridine synthesis P
IDA
SceS000005427
IMP
SceS000005427
ISS
SpoSPCC4G3.16
SPAC18B11.02c

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