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Search term: YOL069W

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name NUF2
SGD link S000005430
Alternative ID YOL069W
Description Component of the evolutionarily conserved kinetochore-associated Ndc80 complex (Ndc80p-Nuf2p-Spc24p-Spc25p); involved in chromosome segregation, spindle checkpoint activity and kinetochore clustering
Synonyms YOL069W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG4438 A--HYPE

KOGs classification KOGs description
CELLULAR PROCESSES AND SIGNALING Centromere-associated protein NUF2

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At1g61000_1 GI:15219846
Homo sapiens (Hsa) Hs13899237 GI:13899237
Saccharomyces cerevisiae (Sce) YOL069w
(S000005430)		 GI:6324503 P33895
Schizosaccharomyces pombe (Spo) SPAC27F1.04c GI:19115444 Q10173
Encephalitozoon cuniculi (Ecu) ECU09g1690 GI:19173290


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000778 condensed nuclear chromosome kinetochore C
IDA
SceS000005430
SpoSPAC27F1.04c
IMP
SceS000005430
IPI
SceS000005430
GO:0000780 condensed nuclear chromosome, centromeric
region		 C
IDA
SceS000005430
IGI
SceS000005430
IPI
SceS000005430
GO:0005634 nucleus C
IDA
SpoSPAC27F1.04c
GO:0005816 spindle pole body C
IDA
SceS000005430
SpoSPAC27F1.04c
GO:0005829 cytosol C
IDA
SpoSPAC27F1.04c
GO:0005876 spindle microtubule C
IDA
SceS000005430
GO:0005886 plasma membrane C
IDA
AthAt1g61000
GO:0031262 Ndc80 complex C
IDA
SceS000005430
IPI
SceS000005430
TAS
SpoSPAC27F1.04c
GO:0031617 NMS complex C
IDA
SpoSPAC27F1.04c
GO:0003674 molecular_function F
ND
AthAt1g61000
GO:0005200 structural constituent of cytoskeleton F
IPI
SceS000005430
GO:0005515 protein binding F
IPI
SpoSPAC27F1.04c
GO:0042803 protein homodimerization activity F
IPI
SpoSPAC27F1.04c
GO:0000278 mitotic cell cycle P
RCA
SceS000005430
GO:0000279 M phase P
RCA
SceS000005430
GO:0007020 microtubule nucleation P
IPI
SceS000005430
GO:0007059 chromosome segregation P
IGI
SceS000005430
IMP
SpoSPAC27F1.04c
GO:0007094 mitotic cell cycle spindle assembly
checkpoint		 P
IMP
SpoSPAC27F1.04c
GO:0008608 attachment of spindle microtubules to
kinetochore		 P
TAS
SpoSPAC27F1.04c
GO:0051455 attachment of spindle microtubules to kinetochore
involved in homologous chromosome
segregation		 P
IMP
SpoSPAC27F1.04c

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
40205

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) NUF2 GI:117968420
Pan troglodytes (Ptr) NUF2 GI:114561067
Canis familiaris (Cfa) NUF2 GI:74006231
Mus musculus (Mmu) Nuf2
(MGI:1914227)		 GI:110625714 Q99P69
Rattus norvegicus (Rno) Nuf2 GI:58865624
Gallus gallus (Gga) NUF2 GI:54020706
Schizosaccharomyces pombe (Spo) nuf2
(SPAC27F1.04c)		 GI:19115444 Q10173
Saccharomyces cerevisiae (Sce) NUF2
(S000005430)		 GI:6324503 P33895
Kluyveromyces lactis (Kla) KLLA0F22451g GI:50312103
Eremothecium gossypii (Ego) AGOS_AEL015W GI:45190592
Magnaporthe grisea (Mgr) MGG_01848 GI:145613143
Neurospora crassa (Ncr) NCU06568.1 GI:32411885


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000775 chromosome, centromeric region C
NAS
HsaNUF2
GO:0000776 kinetochore C
ISO
MmuMGI:1914227
GO:0000778 condensed nuclear chromosome kinetochore C
IDA
SceS000005430
SpoSPAC27F1.04c
IMP
SceS000005430
IPI
SceS000005430
GO:0000780 condensed nuclear chromosome, centromeric
region		 C
IDA
SceS000005430
IGI
SceS000005430
IPI
SceS000005430
GO:0005634 nucleus C
IDA
SpoSPAC27F1.04c
GO:0005816 spindle pole body C
IDA
SceS000005430
SpoSPAC27F1.04c
GO:0005829 cytosol C
IDA
SpoSPAC27F1.04c
GO:0005876 spindle microtubule C
IDA
SceS000005430
GO:0031262 Ndc80 complex C
IDA
HsaNUF2
SceS000005430
IPI
SceS000005430
TAS
SpoSPAC27F1.04c
GO:0031617 NMS complex C
IDA
SpoSPAC27F1.04c
GO:0003674 molecular_function F
ND
HsaNUF2
MmuMGI:1914227
GO:0005200 structural constituent of cytoskeleton F
IPI
SceS000005430
GO:0005515 protein binding F
IPI
HsaNUF2
SpoSPAC27F1.04c
GO:0042803 protein homodimerization activity F
IPI
SpoSPAC27F1.04c
GO:0000278 mitotic cell cycle P
RCA
SceS000005430
GO:0000279 M phase P
RCA
SceS000005430
GO:0007020 microtubule nucleation P
IPI
SceS000005430
GO:0007059 chromosome segregation P
IGI
SceS000005430
IMP
SpoSPAC27F1.04c
NAS
HsaNUF2
GO:0007094 mitotic cell cycle spindle assembly
checkpoint		 P
IMP
SpoSPAC27F1.04c
GO:0008608 attachment of spindle microtubules to
kinetochore		 P
ISO
MmuMGI:1914227
TAS
SpoSPAC27F1.04c
GO:0051455 attachment of spindle microtubules to kinetochore
involved in homologous chromosome
segregation		 P
IMP
SpoSPAC27F1.04c

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_3946

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga86 ENSANGP00000010789
Ashbya gossypii (Ago) ago2491 AEL015W
Candida glabrata (Cgl) cgl3501 CAGL0J11572g
Cryptococcus neoformans (Cne) cne2369 181.m08404
Dictyostelium discoideum (Ddi) ddi5087 DDB0205843
Debaryomyces hansenii (Dha) dha3936 DEHA0E15653g
Drosophila melanogaster (Dme) dme1199 CG8902-PA
(FBgn0031886)
Danio rerio (Dre) dre2288 ENSDARP00000040811
(zgc:56708)		 Q7ZW63
Encephalitozoon cuniculi (Ecu) ecu1441 19173290
Takifugu rubripes (Fru) fru13823 SINFRUP00000161852
Gallus gallus (Gga) gga22259 ENSGALP00000005436
(NUF2)		 Q76I90
Homo sapiens (Hsa) hsa2509 ENSP00000271452
(NUF2)		 Q9BZD4
Kluyveromyces lactis (Kla) kla5083 KLLA0F22451g
Mus musculus (Mmu) mmu1435 ENSMUSP00000028000
(MGI:1914227)		 Q99P69-1
Neurospora crassa (Ncr) ncr6386 NCU06568.2
Oryza sativa (Osa) osa5105 2346.m00143
Oryza sativa (Osa) osa71567 7200.m00087
Oryza sativa (Osa) osa85239 8373.m00141
Rattus norvegicus (Rno) rno9467 ENSRNOP00000003650
(RGD:1307952)		 Q6AYL9
Saccharomyces cerevisiae (Sce) sce5621 YOL069W
(S000005430)
Schizosaccharomyces pombe (Spo) spo2980 SPAC27F1.04c Q10173
Yarrowia lipolytica (Yli) yli371 YALI0A10945g
Yarrowia lipolytica (Yli) yli5185 YALI0E31867g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000776 kinetochore C
IDA
DmeFBgn0031886
FBgn0031886
ISO
MmuMGI:1914227
GO:0000778 condensed nuclear chromosome kinetochore C
IDA
SceS000005430
SpoSPAC27F1.04c
IMP
SceS000005430
IPI
SceS000005430
GO:0000780 condensed nuclear chromosome, centromeric
region		 C
IDA
SceS000005430
IGI
SceS000005430
IPI
SceS000005430
GO:0005634 nucleus C
IDA
SpoSPAC27F1.04c
GO:0005816 spindle pole body C
IDA
SceS000005430
SpoSPAC27F1.04c
GO:0005829 cytosol C
IDA
SpoSPAC27F1.04c
GO:0005876 spindle microtubule C
IDA
SceS000005430
GO:0031262 Ndc80 complex C
IDA
DmeFBgn0031886
SceS000005430
IPI
SceS000005430
TAS
SpoSPAC27F1.04c
GO:0031617 NMS complex C
IDA
SpoSPAC27F1.04c
GO:0003674 molecular_function F
ND
MmuMGI:1914227
GO:0005200 structural constituent of cytoskeleton F
IPI
SceS000005430
GO:0005515 protein binding F
IPI
SpoSPAC27F1.04c
GO:0042803 protein homodimerization activity F
IPI
SpoSPAC27F1.04c
GO:0000278 mitotic cell cycle P
RCA
SceS000005430
GO:0000279 M phase P
RCA
SceS000005430
GO:0007020 microtubule nucleation P
IPI
SceS000005430
GO:0007052 mitotic spindle organization P
IMP
DmeFBgn0031886
GO:0007059 chromosome segregation P
IGI
SceS000005430
IMP
DmeFBgn0031886
SpoSPAC27F1.04c
GO:0007080 mitotic metaphase plate congression P
IMP
DmeFBgn0031886
GO:0007094 mitotic cell cycle spindle assembly
checkpoint		 P
IMP
SpoSPAC27F1.04c
GO:0008608 attachment of spindle microtubules to
kinetochore		 P
ISO
MmuMGI:1914227
TAS
SpoSPAC27F1.04c
GO:0051455 attachment of spindle microtubules to kinetochore
involved in homologous chromosome
segregation		 P
IMP
SpoSPAC27F1.04c

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPAC27F1.04c
(Q10173)		 YOL069W
(S000005430)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000778 condensed nuclear chromosome kinetochore C
IDA
SceS000005430
SpoSPAC27F1.04c
IMP
SceS000005430
IPI
SceS000005430
GO:0000780 condensed nuclear chromosome, centromeric
region		 C
IDA
SceS000005430
IGI
SceS000005430
IPI
SceS000005430
GO:0005634 nucleus C
IDA
SpoSPAC27F1.04c
GO:0005816 spindle pole body C
IDA
SceS000005430
SpoSPAC27F1.04c
GO:0005829 cytosol C
IDA
SpoSPAC27F1.04c
GO:0005876 spindle microtubule C
IDA
SceS000005430
GO:0031262 Ndc80 complex C
IDA
SceS000005430
IPI
SceS000005430
TAS
SpoSPAC27F1.04c
GO:0031617 NMS complex C
IDA
SpoSPAC27F1.04c
GO:0005200 structural constituent of cytoskeleton F
IPI
SceS000005430
GO:0005515 protein binding F
IPI
SpoSPAC27F1.04c
GO:0042803 protein homodimerization activity F
IPI
SpoSPAC27F1.04c
GO:0000278 mitotic cell cycle P
RCA
SceS000005430
GO:0000279 M phase P
RCA
SceS000005430
GO:0007020 microtubule nucleation P
IPI
SceS000005430
GO:0007059 chromosome segregation P
IGI
SceS000005430
IMP
SpoSPAC27F1.04c
GO:0007094 mitotic cell cycle spindle assembly
checkpoint		 P
IMP
SpoSPAC27F1.04c
GO:0008608 attachment of spindle microtubules to
kinetochore		 P
TAS
SpoSPAC27F1.04c
GO:0051455 attachment of spindle microtubules to kinetochore
involved in homologous chromosome
segregation		 P
IMP
SpoSPAC27F1.04c

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Search for gene by ID or name:

Query species:

Include wild-cards:   

Search for GO info:  

GO info in one table:

s.khadayate@ucl.ac.uk