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Search term: YOL077C


Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name BRX1
SGD link S000005437
Alternative ID YOL077C
Description Nucleolar protein, constituent of 66S pre-ribosomal particles; depletion leads to defects in rRNA processing and a block in the assembly of large ribosomal subunits; possesses a sigma(70)-like RNA-binding motif
Synonyms YOL077C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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Query species:

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GO info in one table:


KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG2971 ACDHYPE

KOGs classification KOGs description
INFORMATION STORAGE AND PROCESSING RNA-binding protein required for biogenesis of the ribosomal 60S subunit

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At1g52930 GI:18404250
Arabidopsis thaliana (Ath) At3g15460 GI:18400776
Caenorhabditis elegans (Cel) CE00268
(WBGene00019678)
GI:17554174 P34524
Drosophila melanogaster (Dme) 7292473 GI:7292473
Homo sapiens (Hsa) Hs20545215 GI:20545215
Homo sapiens (Hsa) Hs19311012 GI:19311012
Saccharomyces cerevisiae (Sce) YOL077c
(S000005437)
GI:6324496 Q08235
Schizosaccharomyces pombe (Spo) SPBC800.06 GI:19111899 Q9HGL6
Encephalitozoon cuniculi (Ecu) ECU01g0360 GI:19075045


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
AthAt3g15460
At1g52930
GO:0005634 nucleus C
IDA
SpoSPBC800.06
GO:0005730 nucleolus C
IDA
SpoSPBC800.06
IPI
SceS000005437
ISS
SpoSPBC800.06
GO:0005829 cytosol C
IDA
SpoSPBC800.06
GO:0030687 preribosome, large subunit precursor C
IDA
SceS000005437
GO:0032153 cell division site C
IDA
SpoSPBC800.06
GO:0003674 molecular_function F
ND
AthAt3g15460
GO:0003723 RNA binding F
ISS
SpoSPBC800.06
GO:0008097 5S rRNA binding F
IPI
SceS000005437
GO:0042134 rRNA primary transcript binding F
IPI
SceS000005437
GO:0000003 reproduction P
IMP
CelWBGene00019678
GO:0000027 ribosomal large subunit assembly P
IPI
SceS000005437
GO:0002119 nematode larval development P
IMP
CelWBGene00019678
GO:0006364 rRNA processing P
ISS
SpoSPBC800.06
RCA
SceS000005437
GO:0008150 biological_process P
ND
AthAt3g15460
GO:0009792 embryo development ending in birth or egg
hatching
P
IMP
CelWBGene00019678
GO:0034470 ncRNA processing P
RCA
SceS000005437
GO:0040007 growth P
IMP
CelWBGene00019678
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00019678
GO:0040035 hermaphrodite genitalia development P
IMP
CelWBGene00019678
GO:0042254 ribosome biogenesis P
ISS
SpoSPBC800.06

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
10133

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) BXDC2 GI:55770900
Pan troglodytes (Ptr) BXDC2 GI:114600702
Mus musculus (Mmu) Bxdc2 GI:141802630
Rattus norvegicus (Rno) Bxdc2
(RGD:1308508)
GI:71361619
Gallus gallus (Gga) BXDC2 GI:71895385
Drosophila melanogaster (Dme) CG11583
(FBgn0035524)
GI:85725104
Anopheles gambiae (Aga) AgaP_AGAP005365 GI:158294060
Caenorhabditis elegans (Cel) K12H4.3
(CE00268;
WBGene00019678)
GI:17554174 P34524
Schizosaccharomyces pombe (Spo) brx1
(SPBC800.06)
GI:19111899 Q9HGL6
Saccharomyces cerevisiae (Sce) BRX1
(S000005437)
GI:6324496 Q08235
Kluyveromyces lactis (Kla) KLLA0E17875g GI:50309489
Eremothecium gossypii (Ego) AGOS_AER020W GI:45190626
Magnaporthe grisea (Mgr) MGG_01078 GI:39973551
Neurospora crassa (Ncr) NCU01524.1 GI:32414967
Arabidopsis thaliana (Ath) AT1G52930 GI:18404250
Arabidopsis thaliana (Ath) AT3G15460 GI:18400776
Oryza sativa (Osa) Os02g0591800 GI:115447019
Plasmodium falciparum (Pfa) PF07_0122 GI:124512112


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
AthAt3g15460
At1g52930
GO:0005634 nucleus C
IDA
SpoSPBC800.06
GO:0005730 nucleolus C
IDA
SpoSPBC800.06
IPI
SceS000005437
ISS
DmeFBgn0035524
SpoSPBC800.06
GO:0005829 cytosol C
IDA
SpoSPBC800.06
GO:0030687 preribosome, large subunit precursor C
IDA
SceS000005437
GO:0032153 cell division site C
IDA
SpoSPBC800.06
GO:0003674 molecular_function F
ND
AthAt3g15460
DmeFBgn0035524
GO:0003723 RNA binding F
ISS
SpoSPBC800.06
GO:0008097 5S rRNA binding F
IPI
SceS000005437
GO:0042134 rRNA primary transcript binding F
IPI
SceS000005437
GO:0000003 reproduction P
IMP
CelWBGene00019678
GO:0000027 ribosomal large subunit assembly P
IPI
SceS000005437
GO:0002119 nematode larval development P
IMP
CelWBGene00019678
GO:0006364 rRNA processing P
ISS
SpoSPBC800.06
RCA
SceS000005437
GO:0008150 biological_process P
ND
AthAt3g15460
GO:0009792 embryo development ending in birth or egg
hatching
P
IMP
CelWBGene00019678
GO:0034470 ncRNA processing P
RCA
SceS000005437
GO:0040007 growth P
IMP
CelWBGene00019678
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00019678
GO:0040035 hermaphrodite genitalia development P
IMP
CelWBGene00019678
GO:0042254 ribosome biogenesis P
ISS
SpoSPBC800.06
GO:0042273 ribosomal large subunit biogenesis P
ISS
DmeFBgn0035524

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_1904

Species OrthoMCL
sequence
Model organism
protein page
UniProt link
Anopheles gambiae (Aga) aga774 ENSANGP00000021112
Ashbya gossypii (Ago) ago2525 AER020W
Arabidopsis thaliana (Ath) ath4583 At1g52930.1
Arabidopsis thaliana (Ath) ath13773 At3g15460.1
Caenorhabditis elegans (Cel) cel12700 K12H4.3
(CE00268;
WBGene00019678)
Candida glabrata (Cgl) cgl2867 CAGL0I07975g
Cryptococcus neoformans (Cne) cne3018 167.m03320
Dictyostelium discoideum (Ddi) ddi9493 DDB0187700
Debaryomyces hansenii (Dha) dha6167 DEHA0G10560g
Drosophila melanogaster (Dme) dme7948 CG32253-PA
(FBgn0035524)
Danio rerio (Dre) dre26191 ENSDARP00000029422 Q7SZR8
Encephalitozoon cuniculi (Ecu) ecu1682 19075045
Takifugu rubripes (Fru) fru18922 SINFRUP00000160488
Takifugu rubripes (Fru) fru18923 SINFRUP00000173186
Gallus gallus (Gga) gga28300 ENSGALP00000005322
(BXDC2)
Q5ZLV9
Homo sapiens (Hsa) hsa25113 ENSP00000322432
Homo sapiens (Hsa) hsa25112 ENSP00000338862
(BRIX1)
Q8TDN6
Kluyveromyces lactis (Kla) kla3752 KLLA0E17875g
Mus musculus (Mmu) mmu8774 ENSMUSP00000022855
(MGI:1915082)
Q9DCA5
Neurospora crassa (Ncr) ncr1479 NCU01524.2
Oryza sativa (Osa) osa50504 5852.m00021
Oryza sativa (Osa) osa58036 6456.m00243
Plasmodium falciparum (Pfa) pfa2452 PF07_0122
Rattus norvegicus (Rno) rno15643 ENSRNOP00000024285
(RGD:1308508)
Q4QQT6
Saccharomyces cerevisiae (Sce) sce5628 YOL077C
(S000005437)
Schizosaccharomyces pombe (Spo) spo4736 SPBC800.06 Q9HGL6
Yarrowia lipolytica (Yli) yli1230 YALI0B11880g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
AthAt3g15460
At1g52930
MmuMGI:1915082
GO:0005634 nucleus C
IDA
SpoSPBC800.06
GO:0005730 nucleolus C
IDA
SpoSPBC800.06
IPI
SceS000005437
ISS
DmeFBgn0035524
SpoSPBC800.06
GO:0005829 cytosol C
IDA
SpoSPBC800.06
GO:0030687 preribosome, large subunit precursor C
IDA
SceS000005437
GO:0032153 cell division site C
IDA
SpoSPBC800.06
GO:0003674 molecular_function F
ND
AthAt3g15460
DmeFBgn0035524
MmuMGI:1915082
GO:0003723 RNA binding F
ISS
SpoSPBC800.06
GO:0008097 5S rRNA binding F
IPI
SceS000005437
GO:0042134 rRNA primary transcript binding F
IPI
SceS000005437
GO:0000003 reproduction P
IMP
CelWBGene00019678
GO:0000027 ribosomal large subunit assembly P
IPI
SceS000005437
GO:0002119 nematode larval development P
IMP
CelWBGene00019678
GO:0006364 rRNA processing P
ISS
SpoSPBC800.06
RCA
SceS000005437
GO:0008150 biological_process P
ND
AthAt3g15460
MmuMGI:1915082
GO:0009792 embryo development ending in birth or egg
hatching
P
IMP
CelWBGene00019678
GO:0034470 ncRNA processing P
RCA
SceS000005437
GO:0040007 growth P
IMP
CelWBGene00019678
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00019678
GO:0040035 hermaphrodite genitalia development P
IMP
CelWBGene00019678
GO:0042254 ribosome biogenesis P
ISS
SpoSPBC800.06
GO:0042273 ribosomal large subunit biogenesis P
ISS
DmeFBgn0035524

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Curated yeast ortholog results:

S. pombe
systematic ID
S. cerevisiae
systematic ID
SPBC800.06
(Q9HGL6)
YOL077C
(S000005437)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SpoSPBC800.06
GO:0005730 nucleolus C
IDA
SpoSPBC800.06
IPI
SceS000005437
ISS
SpoSPBC800.06
GO:0005829 cytosol C
IDA
SpoSPBC800.06
GO:0030687 preribosome, large subunit precursor C
IDA
SceS000005437
GO:0032153 cell division site C
IDA
SpoSPBC800.06
GO:0003723 RNA binding F
ISS
SpoSPBC800.06
GO:0008097 5S rRNA binding F
IPI
SceS000005437
GO:0042134 rRNA primary transcript binding F
IPI
SceS000005437
GO:0000027 ribosomal large subunit assembly P
IPI
SceS000005437
GO:0006364 rRNA processing P
ISS
SpoSPBC800.06
RCA
SceS000005437
GO:0034470 ncRNA processing P
RCA
SceS000005437
GO:0042254 ribosome biogenesis P
ISS
SpoSPBC800.06

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Search for gene by ID or name:

Query species:

Include wild-cards:   

Search for GO info:  

GO info in one table:

s.khadayate@ucl.ac.uk