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Search term: YOL119C

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name MCH4
SGD link S000005479
Alternative ID YOL119C
Description Protein with similarity to mammalian monocarboxylate permeases, which are involved in transport of monocarboxylic acids across the plasma membrane; mutant is not deficient in monocarboxylate transport
Synonyms YOL119C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG2504 -CDHY--

KOGs classification KOGs description
METABOLISM Monocarboxylate transporter

Species KOG link NCBI link UniProt link
Homo sapiens (Hsa) Hs18699730
(SLC16A10)		 GI:18699730 Q8TF71
Homo sapiens (Hsa) Hs19923753 GI:19923753
Homo sapiens (Hsa) Hs20472343 GI:20472343
Homo sapiens (Hsa) Hs20474082 GI:20474082
Homo sapiens (Hsa) Hs22049062 GI:22049062
Homo sapiens (Hsa) Hs22064599 GI:22064599
Homo sapiens (Hsa) Hs20559959 GI:20559959
Homo sapiens (Hsa) Hs18553168 GI:18553168
Caenorhabditis elegans (Cel) CE02803 GI:17568709
Drosophila melanogaster (Dme) 7292012
(FBgn0035173)		 GI:19923028
Drosophila melanogaster (Dme) 7290288 GI:7290288
Caenorhabditis elegans (Cel) CE12336
(WBGene00010834)		 GI:17568977 Q93896
Caenorhabditis elegans (Cel) CE04864
(WBGene00020168)		 GI:17535933 Q22109
Homo sapiens (Hsa) Hs4759120 GI:4759120
Drosophila melanogaster (Dme) 7302291 GI:7302291
Homo sapiens (Hsa) Hs4759116
(SLC16A5)		 GI:4759116 O15375
Drosophila melanogaster (Dme) 7303156 GI:7303156
Homo sapiens (Hsa) Hs4759114
(SLC16A4)		 GI:4759114 O15374
Homo sapiens (Hsa) Hs4759112 GI:4759112 O15427
Saccharomyces cerevisiae (Sce) YNL125c
(S000005069)		 GI:6324204 P53918
Caenorhabditis elegans (Cel) CE05457 GI:17551098
Caenorhabditis elegans (Cel) CE29573
(WBGene00015676)		 GI:17550316 O17328
Caenorhabditis elegans (Cel) CE20478
(WBGene00015273)		 GI:17557434 Q9UAT3
Drosophila melanogaster (Dme) 7295764
(FBgn0031568)		 GI:20129213
Drosophila melanogaster (Dme) 7293576
(out)		 GI:18860535 Q9V3F9
Drosophila melanogaster (Dme) 7293575 GI:7293575
Drosophila melanogaster (Dme) 7293565 GI:7293565
Drosophila melanogaster (Dme) 7303562 GI:7303562
Drosophila melanogaster (Dme) 7293573 GI:7293573
Drosophila melanogaster (Dme) 7303008 GI:7303008 Q0E960
Drosophila melanogaster (Dme) 7302232 GI:7302232
Homo sapiens (Hsa) Hs4759118 GI:4759118
Homo sapiens (Hsa) Hs7019529 GI:7019529
Drosophila melanogaster (Dme) 7303213
(FBgn0033913)		 GI:19922230 Q7K1L4
Saccharomyces cerevisiae (Sce) YKL221w
(S000001704)		 GI:6322628 P36032
Saccharomyces cerevisiae (Sce) YOL119c
(S000005479)		 GI:6324453 Q08268
Caenorhabditis elegans (Cel) CE28872 GI:17566092
Caenorhabditis elegans (Cel) CE03442 GI:17568321
Drosophila melanogaster (Dme) 7293574 GI:18860531
Drosophila melanogaster (Dme) 7299667 GI:7299667
Homo sapiens (Hsa) Hs5730045
(SLC16A2)		 GI:5730045 P36021
Saccharomyces cerevisiae (Sce) YOR306c
(S000005833)		 GI:6324882 Q08777
Caenorhabditis elegans (Cel) CE27947
(WBGene00017369)		 GI:17533091
Caenorhabditis elegans (Cel) CE21446 GI:17565296


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000329 fungal-type vacuole membrane C
IDA
SceS000005479
GO:0005624 membrane fraction C
TAS
HsaSLC16A4
SLC16A5
SLC16A2
GO:0005739 mitochondrion C
IDA
SceS000005069
GO:0005886 plasma membrane C
IDA
SceS000005833
GO:0005887 integral to plasma membrane C
TAS
HsaSLC16A4
SLC16A5
SLC16A2
GO:0016020 membrane C
ISS
SceS000005069
S000001704
GO:0016323 basolateral plasma membrane C
TAS
HsaSLC16A10
GO:0005215 transporter activity F
ISS
SceS000001704
S000005069
S000005479
TAS
HsaSLC16A2
GO:0008028 monocarboxylic acid transmembrane transporter
activity		 F
ISS
DmeFBgn0031568
out
TAS
HsaSLC16A5
SLC16A4
SLC16A2
GO:0015355 secondary active monocarboxylate transmembrane
transporter activity		 F
ISS
DmeFBgn0035173
NAS
DmeFBgn0033913
GO:0032217 riboflavin transporter activity F
IGI
SceS000005833
GO:0000003 reproduction P
IMP
CelWBGene00015676
GO:0002119 nematode larval development P
IMP
CelWBGene00015676
GO:0006082 organic acid metabolic process P
RCA
SceS000005479
GO:0006519 cellular amino acid and derivative metabolic
process		 P
RCA
SceS000005479
GO:0006725 cellular aromatic compound metabolic
process		 P
RCA
SceS000005479
GO:0006807 nitrogen compound metabolic process P
RCA
SceS000005479
GO:0006810 transport P
ISS
SceS000005069
S000001704
S000005479
TAS
HsaSLC16A2
GO:0006865 amino acid transport P
EXP
HsaSLC16A10
GO:0007281 germ cell development P
IMP
Dmeout
GO:0012501 programmed cell death P
IMP
Dmeout
GO:0015718 monocarboxylic acid transport P
TAS
HsaSLC16A2
SLC16A5
SLC16A4
GO:0015801 aromatic amino acid transport P
TAS
HsaSLC16A10
GO:0032218 riboflavin transport P
IGI
SceS000005833
GO:0035234 germ cell programmed cell death P
TAS
Dmeout
GO:0040007 growth P
IMP
CelWBGene00015676
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00017369

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
74814

Species Gene ID NCBI link UniProt link
Saccharomyces cerevisiae (Sce) MCH4
(S000005479)		 GI:6324453 Q08268
Kluyveromyces lactis (Kla) KLLA0A07249g GI:50302771


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000329 fungal-type vacuole membrane C
IDA
SceS000005479
GO:0005215 transporter activity F
ISS
SceS000005479
GO:0006082 organic acid metabolic process P
RCA
SceS000005479
GO:0006519 cellular amino acid and derivative metabolic
process		 P
RCA
SceS000005479
GO:0006725 cellular aromatic compound metabolic
process		 P
RCA
SceS000005479
GO:0006807 nitrogen compound metabolic process P
RCA
SceS000005479
GO:0006810 transport P
ISS
SceS000005479

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_5644

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga7889 ENSANGP00000018243
Ashbya gossypii (Ago) ago1586 ADL155C
Ashbya gossypii (Ago) ago1585 ADL156C
Candida glabrata (Cgl) cgl1031 CAGL0E02035g
Cryptococcus neoformans (Cne) cne3988 185.m02588
Debaryomyces hansenii (Dha) dha5228 DEHA0F18821g
Debaryomyces hansenii (Dha) dha6440 DEHA0G16588g
Debaryomyces hansenii (Dha) dha6614 DEHA0G20493g
Drosophila melanogaster (Dme) dme4553 CG8271-PA
(FBgn0033657)
Danio rerio (Dre) dre17227 ENSDARP00000010712
Danio rerio (Dre) dre10119 ENSDARP00000015228
Kluyveromyces lactis (Kla) kla319 KLLA0A07249g
Kluyveromyces lactis (Kla) kla4223 KLLA0F03168g
Neurospora crassa (Ncr) ncr5992 NCU06167.2
Rattus norvegicus (Rno) rno31764 ENSRNOP00000042040
(RGD:628608)		 Q8K1P8
Saccharomyces cerevisiae (Sce) sce5677 YOL119C
(S000005479)
Yarrowia lipolytica (Yli) yli14 YALI0A00418g
Yarrowia lipolytica (Yli) yli904 YALI0B04004g
Yarrowia lipolytica (Yli) yli4083 YALI0E05313g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000329 fungal-type vacuole membrane C
IDA
SceS000005479
GO:0005215 transporter activity F
ISS
SceS000005479
GO:0008028 monocarboxylic acid transmembrane transporter
activity		 F
IDA
DmeFBgn0033657
GO:0015355 secondary active monocarboxylate transmembrane
transporter activity		 F
ISS
DmeFBgn0033657
GO:0006082 organic acid metabolic process P
RCA
SceS000005479
GO:0006519 cellular amino acid and derivative metabolic
process		 P
RCA
SceS000005479
GO:0006725 cellular aromatic compound metabolic
process		 P
RCA
SceS000005479
GO:0006807 nitrogen compound metabolic process P
RCA
SceS000005479
GO:0006810 transport P
ISS
SceS000005479

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