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Search term: YOL123W

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name HRP1
SGD link S000005483
Alternative ID YOL123W
Description Subunit of cleavage factor I, a five-subunit complex required for the cleavage and polyadenylation of pre-mRNA 3' ends; RRM-containing heteronuclear RNA binding protein and hnRNPA/B family member that binds to poly (A) signal sequences
Synonyms YOL123W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG4205 ACDHYPE

KOGs classification KOGs description
INFORMATION STORAGE AND PROCESSING RNA-binding protein musashi/mRNA cleavage and polyadenylation factor I complex, subunit HRP1

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At2g33410 GI:15226106
Arabidopsis thaliana (Ath) At3g07810 GI:6648193
Arabidopsis thaliana (Ath) At4g14300 GI:15236467
Arabidopsis thaliana (Ath) At4g26650 GI:7487039
Arabidopsis thaliana (Ath) At5g47620 GI:9758790
Arabidopsis thaliana (Ath) At5g55550 GI:9758187
Caenorhabditis elegans (Cel) CE29008
(WBGene00022235)		 GI:17544098
Caenorhabditis elegans (Cel) CE29337
(WBGene00003423)		 GI:17554332 Q21911
Drosophila melanogaster (Dme) 7294010 GI:7294010
Drosophila melanogaster (Dme) 7297190
(FBgn0004838)		 GI:17136728
Drosophila melanogaster (Dme) 7299785 GI:7299785
Drosophila melanogaster (Dme) 7301350 GI:7301350
Homo sapiens (Hsa) Hs14731484 GI:14731484
Homo sapiens (Hsa) Hs17452185 GI:17452185
Homo sapiens (Hsa) Hs17486819_2 GI:17486819
Homo sapiens (Hsa) Hs20373175
(MSI2)		 GI:20373175 Q96DH6
Homo sapiens (Hsa) Hs20480107 GI:20480107
Homo sapiens (Hsa) Hs20537262 GI:20537262
Homo sapiens (Hsa) Hs22041301 GI:22041301
Homo sapiens (Hsa) Hs22041959 GI:22041959
Homo sapiens (Hsa) Hs22043440 GI:22043440
Homo sapiens (Hsa) Hs22044662 GI:22044662
Homo sapiens (Hsa) Hs22055112 GI:22055112
Homo sapiens (Hsa) Hs22062697 GI:22062697
Homo sapiens (Hsa) Hs22067735 GI:22067735
Homo sapiens (Hsa) Hs4505255
(MSI1)		 GI:4505255 O43347
Homo sapiens (Hsa) Hs9506537 GI:9506537
Saccharomyces cerevisiae (Sce) YOL123w
(S000005483)		 GI:6324449 Q99383
Schizosaccharomyces pombe (Spo) SPBC660.15 GI:19111886 O94432
Encephalitozoon cuniculi (Ecu) ECU03g0730 GI:19173032 Q8SSA1
Encephalitozoon cuniculi (Ecu) ECU04g1300 GI:19074208 Q8SVS1
Encephalitozoon cuniculi (Ecu) ECU05g1440 GI:19173684 Q8SRU2


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
AthAt2g33410
At5g47620
At4g14300
GO:0005634 nucleus C
IDA
SceS000005483
SpoSPBC660.15
ISS
SpoSPBC660.15
GO:0005654 nucleoplasm C
IDA
DmeFBgn0004838
GO:0005737 cytoplasm C
IDA
CelWBGene00003423
SceS000005483
ISS
SpoSPBC660.15
GO:0005849 mRNA cleavage factor complex C
IPI
SceS000005483
ISS
SpoSPBC660.15
GO:0010494 stress granule C
IDA
SceS000005483
GO:0030529 ribonucleoprotein complex C
IDA
DmeFBgn0004838
IPI
DmeFBgn0004838
ISS
DmeFBgn0004838
NAS
DmeFBgn0004838
GO:0043234 protein complex C
IPI
DmeFBgn0004838
GO:0003697 single-stranded DNA binding F
IDA
DmeFBgn0004838
GO:0003723 RNA binding F
IDA
SceS000005483
ISS
AthAt4g14300
At5g55550
At3g07810
At2g33410
At4g26650
At5g47620
SpoSPBC660.15
TAS
HsaMSI1
GO:0003729 mRNA binding F
IDA
SceS000005483
ISS
DmeFBgn0004838
NAS
DmeFBgn0004838
GO:0003730 mRNA 3'-UTR binding F
IDA
DmeFBgn0004838
NAS
SpoSPBC660.15
TAS
DmeFBgn0004838
GO:0005515 protein binding F
IPI
DmeFBgn0004838
GO:0048027 mRNA 5'-UTR binding F
NAS
DmeFBgn0004838
TAS
DmeFBgn0004838
GO:0000003 reproduction P
IMP
CelWBGene00022235
GO:0006378 mRNA polyadenylation P
IDA
SceS000005483
IMP
SceS000005483
ISS
SpoSPBC660.15
GO:0006379 mRNA cleavage P
IDA
SceS000005483
ISS
SpoSPBC660.15
GO:0006397 mRNA processing P
ISS
DmeFBgn0004838
GO:0007298 border follicle cell migration P
IMP
DmeFBgn0004838
GO:0007317 regulation of pole plasm oskar mRNA
localization		 P
IMP
DmeFBgn0004838
GO:0007319 negative regulation of oskar mRNA
translation		 P
TAS
DmeFBgn0004838
GO:0007399 nervous system development P
TAS
HsaMSI1
GO:0007411 axon guidance P
IMP
DmeFBgn0004838
GO:0008150 biological_process P
ND
AthAt5g47620
At2g33410
At4g14300
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00003423
GO:0045451 pole plasm oskar mRNA localization P
IMP
DmeFBgn0004838
GO:0045727 positive regulation of translation P
IDA
DmeFBgn0004838
GO:0048024 regulation of nuclear mRNA splicing, via
spliceosome		 P
IMP
DmeFBgn0004838

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
113674

Species Gene ID NCBI link UniProt link
Schizosaccharomyces pombe (Spo) SPBC660.15 GI:19111886 O94432
Saccharomyces cerevisiae (Sce) HRP1
(S000005483)		 GI:6324449 Q99383
Kluyveromyces lactis (Kla) KLLA0C12925g GI:50305631
Eremothecium gossypii (Ego) AGOS_ADL160W GI:45187713


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SceS000005483
SpoSPBC660.15
ISS
SpoSPBC660.15
GO:0005737 cytoplasm C
IDA
SceS000005483
ISS
SpoSPBC660.15
GO:0005849 mRNA cleavage factor complex C
IPI
SceS000005483
ISS
SpoSPBC660.15
GO:0010494 stress granule C
IDA
SceS000005483
GO:0003723 RNA binding F
IDA
SceS000005483
ISS
SpoSPBC660.15
GO:0003729 mRNA binding F
IDA
SceS000005483
GO:0003730 mRNA 3'-UTR binding F
NAS
SpoSPBC660.15
GO:0006378 mRNA polyadenylation P
IDA
SceS000005483
IMP
SceS000005483
ISS
SpoSPBC660.15
GO:0006379 mRNA cleavage P
IDA
SceS000005483
ISS
SpoSPBC660.15

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_481

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga4542 ENSANGP00000026814
Arabidopsis thaliana (Ath) ath25821 At5g40490.1
Caenorhabditis elegans (Cel) cel8874 F42A6.7a
(CE17059;
WBGene00001999)
Caenorhabditis elegans (Cel) cel8875 F42A6.7b
(CE31510)
Candida glabrata (Cgl) cgl1027 CAGL0E01947g
Candida glabrata (Cgl) cgl4821 CAGL0M03795g
Dictyostelium discoideum (Ddi) ddi10461 DDB0184371
Drosophila melanogaster (Dme) dme12449 CG12749-PA
(FBgn0004237)
Drosophila melanogaster (Dme) dme12450 CG12749-PB
(FBgn0004237)
Drosophila melanogaster (Dme) dme14880 CG9983-PA
(FBgn0001215)
Drosophila melanogaster (Dme) dme14882 CG9983-PB
(FBgn0001215)
Drosophila melanogaster (Dme) dme14884 CG9983-PC
(FBgn0001215)
Drosophila melanogaster (Dme) dme14885 CG9983-PD
(FBgn0001215)
Drosophila melanogaster (Dme) dme14881 CG9983-PE
(FBgn0001215)
Drosophila melanogaster (Dme) dme14883 CG9983-PF
(FBgn0001215)
Danio rerio (Dre) dre24713 ENSDARP00000002918
Danio rerio (Dre) dre5228 ENSDARP00000003180
Danio rerio (Dre) dre24712 ENSDARP00000013977
Danio rerio (Dre) dre31229 ENSDARP00000024594
(zgc:66127)		 Q7SXQ3
Danio rerio (Dre) dre5820 ENSDARP00000029150
Danio rerio (Dre) dre5857 ENSDARP00000046212
Danio rerio (Dre) dre5242 ENSDARP00000046527
(LOC573578)
Danio rerio (Dre) dre5821 ENSDARP00000049018
Danio rerio (Dre) dre5856 ENSDARP00000049816
Takifugu rubripes (Fru) fru11207 SINFRUP00000131828
Takifugu rubripes (Fru) fru27966 SINFRUP00000140618
Takifugu rubripes (Fru) fru11208 SINFRUP00000170917
Gallus gallus (Gga) gga5978 ENSGALP00000009933
(HNRNPA0)
Gallus gallus (Gga) gga21481 ENSGALP00000015037
(HNRPA3)		 Q5ZLB3
Gallus gallus (Gga) gga9871 ENSGALP00000017953
Gallus gallus (Gga) gga9872 ENSGALP00000017954
(RCJMB04_2g17)		 Q5ZME1
Gallus gallus (Gga) gga9874 ENSGALP00000017956
Homo sapiens (Hsa) hsa28351 ENSP00000265397
Homo sapiens (Hsa) hsa18916 ENSP00000302894
Homo sapiens (Hsa) hsa14043 ENSP00000313616
(MSI2)		 Q96DH6-2
Homo sapiens (Hsa) hsa25775 ENSP00000316042
(HNRNPA0)		 Q13151
Homo sapiens (Hsa) hsa33092 ENSP00000333504
(HNRNPA1)		 P09651-2
Homo sapiens (Hsa) hsa7605 ENSP00000341826
(HNRNPA1)		 P09651-1
Homo sapiens (Hsa) hsa28350 ENSP00000346694
(HNRNPA2B1)		 P22626-1
Homo sapiens (Hsa) hsa28349 ENSP00000354021
(HNRNPA2B1)		 P22626-1
Mus musculus (Mmu) mmu7064 ENSMUSP00000007980
(MGI:1924384)		 Q9CX86
Mus musculus (Mmu) mmu21863 ENSMUSP00000031860
Mus musculus (Mmu) mmu9233 ENSMUSP00000054675
Mus musculus (Mmu) mmu29236 ENSMUSP00000072189
Mus musculus (Mmu) mmu9240 ENSMUSP00000075081
Mus musculus (Mmu) mmu14812 ENSMUSP00000078963
Oryza sativa (Osa) osa40848 5103.m00153
Oryza sativa (Osa) osa40854 5103.m00183
Oryza sativa (Osa) osa40938 5105.m00194
Oryza sativa (Osa) osa53568 6135.m00112
Oryza sativa (Osa) osa63464 6622.m00179
Rattus norvegicus (Rno) rno18822 ENSRNOP00000002122
Rattus norvegicus (Rno) rno16257 ENSRNOP00000009539
Rattus norvegicus (Rno) rno21260 ENSRNOP00000015152
(RGD:1310403)		 A7VJC2-1
Rattus norvegicus (Rno) rno9280 ENSRNOP00000021852
Rattus norvegicus (Rno) rno9281 ENSRNOP00000029253
(GI:685894)
Rattus norvegicus (Rno) rno17217 ENSRNOP00000029576
Rattus norvegicus (Rno) rno15922 ENSRNOP00000032420
(RGD:1304899)
Rattus norvegicus (Rno) rno9279 ENSRNOP00000049647
Saccharomyces cerevisiae (Sce) sce5681 YOL123W
(S000005483)
Schizosaccharomyces pombe (Spo) spo1357 SPBC660.15 O94432
Yarrowia lipolytica (Yli) yli2278 YALI0C13860g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000781 chromosome, telomeric region C
IDA
CelWBGene00001999
GO:0000785 chromatin C
IDA
DmeFBgn0004237
GO:0005575 cellular_component C
ND
AthAt5g40490
MmuMGI:1924384
GO:0005634 nucleus C
IC
DmeFBgn0004237
IDA
DmeFBgn0004237
SceS000005483
SpoSPBC660.15
ISS
SpoSPBC660.15
GO:0005654 nucleoplasm C
IDA
DmeFBgn0004237
GO:0005703 polytene chromosome puff C
IDA
DmeFBgn0004237
FBgn0001215
GO:0005737 cytoplasm C
IDA
SceS000005483
ISS
SpoSPBC660.15
GO:0005849 mRNA cleavage factor complex C
IPI
SceS000005483
ISS
SpoSPBC660.15
GO:0010494 stress granule C
IDA
SceS000005483
GO:0030529 ribonucleoprotein complex C
IDA
DmeFBgn0001215
FBgn0004237
IPI
DmeFBgn0004237
FBgn0001215
ISS
DmeFBgn0004237
FBgn0001215
NAS
DmeFBgn0004237
FBgn0001215
GO:0030530 heterogeneous nuclear ribonucleoprotein
complex		 C
ISS
DmeFBgn0004237
FBgn0001215
GO:0035062 omega speckle C
IDA
DmeFBgn0004237
GO:0003674 molecular_function F
ND
MmuMGI:1924384
GO:0003723 RNA binding F
IDA
SceS000005483
ISS
AthAt5g40490
SpoSPBC660.15
GO:0003729 mRNA binding F
IDA
SceS000005483
ISS
DmeFBgn0004237
FBgn0001215
NAS
DmeFBgn0004237
FBgn0001215
GO:0003730 mRNA 3'-UTR binding F
NAS
SpoSPBC660.15
GO:0043565 sequence-specific DNA binding F
IDA
DmeFBgn0004237
FBgn0001215
GO:0000003 reproduction P
IMP
CelWBGene00001999
GO:0000381 regulation of alternative nuclear mRNA splicing,
via spliceosome		 P
IMP
DmeFBgn0004237
FBgn0001215
GO:0002009 morphogenesis of an epithelium P
IMP
CelWBGene00001999
GO:0002119 nematode larval development P
IMP
CelWBGene00001999
GO:0006378 mRNA polyadenylation P
IDA
SceS000005483
IMP
SceS000005483
ISS
SpoSPBC660.15
GO:0006379 mRNA cleavage P
IDA
SceS000005483
ISS
SpoSPBC660.15
GO:0008150 biological_process P
ND
AthAt5g40490
MmuMGI:1924384
GO:0008340 determination of adult lifespan P
IMP
CelWBGene00001999
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00001999
GO:0033119 negative regulation of RNA splicing P
IMP
DmeFBgn0001215
GO:0040007 growth P
IMP
CelWBGene00001999
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00001999
GO:0040015 negative regulation of multicellular organism
growth		 P
IMP
CelWBGene00001999
GO:0040035 hermaphrodite genitalia development P
IMP
CelWBGene00001999
GO:0048477 oogenesis P
IMP
CelWBGene00001999

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPBC660.15
(O94432)		 YOL123W
(S000005483)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SceS000005483
SpoSPBC660.15
ISS
SpoSPBC660.15
GO:0005737 cytoplasm C
IDA
SceS000005483
ISS
SpoSPBC660.15
GO:0005849 mRNA cleavage factor complex C
IPI
SceS000005483
ISS
SpoSPBC660.15
GO:0010494 stress granule C
IDA
SceS000005483
GO:0003723 RNA binding F
IDA
SceS000005483
ISS
SpoSPBC660.15
GO:0003729 mRNA binding F
IDA
SceS000005483
GO:0003730 mRNA 3'-UTR binding F
NAS
SpoSPBC660.15
GO:0006378 mRNA polyadenylation P
IDA
SceS000005483
IMP
SceS000005483
ISS
SpoSPBC660.15
GO:0006379 mRNA cleavage P
IDA
SceS000005483
ISS
SpoSPBC660.15

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s.khadayate@ucl.ac.uk