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Search term: YOL127W


Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name RPL25
SGD link S000005487
Alternative ID YOL127W
Description Primary rRNA-binding ribosomal protein component of the large (60S) ribosomal subunit, has similarity to E. coli L23 and rat L23a ribosomal proteins; binds to 26S rRNA via a conserved C-terminal motif
Synonyms YOL127W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:


KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG1751 ACDHYPE

KOGs classification KOGs description
INFORMATION STORAGE AND PROCESSING 60s ribosomal protein L23

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At2g39460 GI:15225470
Arabidopsis thaliana (Ath) At3g55280 GI:15233226
Caenorhabditis elegans (Cel) CE02777
(WBGene00004438)
GI:17569427 P48162
Caenorhabditis elegans (Cel) CE05721
(WBGene00004439)
GI:17508675 Q20647
Drosophila melanogaster (Dme) 7292133 GI:7292133
Homo sapiens (Hsa) Hs17105394
(RPL23A)
GI:17105394 P62750
Homo sapiens (Hsa) Hs17447612 GI:17447612
Homo sapiens (Hsa) Hs17450912 GI:17450912
Homo sapiens (Hsa) Hs17454000 GI:17454000
Homo sapiens (Hsa) Hs17454507 GI:17454507
Homo sapiens (Hsa) Hs17457126 GI:17457126
Homo sapiens (Hsa) Hs17458937 GI:17458937
Homo sapiens (Hsa) Hs17460354 GI:17460354
Homo sapiens (Hsa) Hs17474260 GI:17474260
Homo sapiens (Hsa) Hs18551250 GI:18551250
Homo sapiens (Hsa) Hs18551861 GI:18551861
Homo sapiens (Hsa) Hs18552515 GI:18552515
Homo sapiens (Hsa) Hs18574981 GI:18574981
Homo sapiens (Hsa) Hs18585400 GI:18585400
Homo sapiens (Hsa) Hs18599382 GI:18599382
Homo sapiens (Hsa) Hs18605389 GI:18597862
Homo sapiens (Hsa) Hs20470310 GI:20470310
Homo sapiens (Hsa) Hs20485355 GI:20485355
Homo sapiens (Hsa) Hs20538039 GI:20538039
Homo sapiens (Hsa) Hs20542410 GI:20542410
Homo sapiens (Hsa) Hs20544310 GI:20544310
Homo sapiens (Hsa) Hs20552056 GI:20552056
Homo sapiens (Hsa) Hs20561624 GI:20561624
Homo sapiens (Hsa) Hs22043659 GI:22043659
Homo sapiens (Hsa) Hs22043971 GI:22043971
Homo sapiens (Hsa) Hs22044201 GI:22044201
Homo sapiens (Hsa) Hs22045203 GI:22045203
Homo sapiens (Hsa) Hs22046890 GI:22046890
Homo sapiens (Hsa) Hs22046899 GI:22046899
Homo sapiens (Hsa) Hs22063285 GI:22063285
Homo sapiens (Hsa) Hs22069417 GI:22069417
Homo sapiens (Hsa) Hs9910200 GI:9910200
Saccharomyces cerevisiae (Sce) YOL127w
(S000005487)
GI:6324445 P04456
Schizosaccharomyces pombe (Spo) SPBC106.18 GI:19111959 Q10330
Schizosaccharomyces pombe (Spo) SPBC4F6.04 GI:19112896 O74391
Encephalitozoon cuniculi (Ecu) ECU08g1910 GI:19173515 Q8SR87
Encephalitozoon cuniculi (Ecu) ECU10g0160 GI:19074625 Q8SR81


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005618 cell wall C
IDA
AthAt2g39460
GO:0005622 intracellular C
ISS
AthAt3g55280
At2g39460
GO:0005730 nucleolus C
IDA
AthAt2g39460
GO:0005737 cytoplasm C
IDA
SpoSPBC4F6.04
GO:0005829 cytosol C
EXP
HsaRPL23A
IDA
SpoSPBC106.18
GO:0015934 large ribosomal subunit C
TAS
AthAt2g39460
GO:0016020 membrane C
IDA
AthAt3g55280
GO:0022625 cytosolic large ribosomal subunit C
IDA
AthAt3g55280
At2g39460
ISS
AthAt2g39460
At3g55280
SpoSPBC106.18
SPBC4F6.04
TAS
HsaRPL23A
SceS000005487
GO:0022626 cytosolic ribosome C
IDA
AthAt3g55280
At2g39460
GO:0003723 RNA binding F
IDA
SceS000005487
ISS
AthAt3g55280
At2g39460
TAS
HsaRPL23A
GO:0003735 structural constituent of ribosome F
ISS
AthAt2g39460
At3g55280
SpoSPBC4F6.04
SPBC106.18
TAS
SceS000005487
GO:0005515 protein binding F
IPI
HsaRPL23A
GO:0019843 rRNA binding F
ISS
SpoSPBC106.18
GO:0000003 reproduction P
IMP
CelWBGene00004438
WBGene00004439
GO:0000027 ribosomal large subunit assembly P
IMP
SceS000005487
ISS
SpoSPBC106.18
SPBC4F6.04
GO:0002119 nematode larval development P
IMP
CelWBGene00004438
GO:0006412 translation P
ISS
AthAt3g55280
At2g39460
SpoSPBC4F6.04
SPBC106.18
TAS
AthAt2g39460
HsaRPL23A
SceS000005487
GO:0006414 translational elongation P
EXP
HsaRPL23A
GO:0006898 receptor-mediated endocytosis P
IMP
CelWBGene00004439
GO:0006979 response to oxidative stress P
IEP
AthAt2g39460
At3g55280
GO:0009409 response to cold P
IEP
AthAt3g55280
At2g39460
GO:0009644 response to high light intensity P
IEP
AthAt2g39460
At3g55280
GO:0009790 embryo development P
IMP
CelWBGene00004439
GO:0009792 embryo development ending in birth or egg
hatching
P
IMP
CelWBGene00004438
WBGene00004439
GO:0016246 RNA interference P
IMP
CelWBGene00004439
GO:0040002 collagen and cuticulin-based cuticle
development
P
IMP
CelWBGene00004439
GO:0040007 growth P
IMP
CelWBGene00004438
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00004439
WBGene00004438
GO:0040018 positive regulation of multicellular organism
growth
P
IMP
CelWBGene00004438
GO:0040035 hermaphrodite genitalia development P
IMP
CelWBGene00004439
WBGene00004438
GO:0042254 ribosome biogenesis P
ISS
AthAt2g39460
At3g55280
SpoSPBC106.18

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
112175

Species Gene ID NCBI link UniProt link
Pan troglodytes (Ptr) LOC736894 GI:114669745
Canis familiaris (Cfa) LOC610129 GI:74000803
Canis familiaris (Cfa) LOC478212 GI:73957982
Mus musculus (Mmu) Gm3362 GI:149266479
Rattus norvegicus (Rno) LOC689899 GI:62660318
Schizosaccharomyces pombe (Spo) rpl2501
(SPBC106.18)
GI:19111959 Q10330
Schizosaccharomyces pombe (Spo) rpl23a-2 GI:19112896
Saccharomyces cerevisiae (Sce) RPL25
(S000005487)
GI:6324445 P04456
Kluyveromyces lactis (Kla) KLLA0E07458g GI:50308567
Eremothecium gossypii (Ego) AGOS_ADL166W GI:45187707
Magnaporthe grisea (Mgr) MGG_10185 GI:39969149
Neurospora crassa (Ncr) NCU06226.1 GI:32411201


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005829 cytosol C
IDA
SpoSPBC106.18
GO:0022625 cytosolic large ribosomal subunit C
ISS
SpoSPBC106.18
TAS
SceS000005487
GO:0003723 RNA binding F
IDA
SceS000005487
GO:0003735 structural constituent of ribosome F
ISS
SpoSPBC106.18
TAS
SceS000005487
GO:0019843 rRNA binding F
ISS
SpoSPBC106.18
GO:0000027 ribosomal large subunit assembly P
IMP
SceS000005487
ISS
SpoSPBC106.18
GO:0006412 translation P
ISS
SpoSPBC106.18
TAS
SceS000005487
GO:0042254 ribosome biogenesis P
ISS
SpoSPBC106.18

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_742

Species OrthoMCL
sequence
Model organism
protein page
UniProt link
Anopheles gambiae (Aga) aga1487 ENSANGP00000012554
Anopheles gambiae (Aga) aga1488 ENSANGP00000024740
Ashbya gossypii (Ago) ago1575 ADL166W
Arabidopsis thaliana (Ath) ath11061 At2g39460.1
Arabidopsis thaliana (Ath) ath16909 At3g55280.1
Caenorhabditis elegans (Cel) cel9809 F52B5.6
(CE05721;
WBGene00004439)
Caenorhabditis elegans (Cel) cel10414 F55D10.2
(CE02777;
WBGene00004438)
Candida glabrata (Cgl) cgl4824 CAGL0M03861g
Cryptococcus neoformans (Cne) cne5188 179.m00034
Dictyostelium discoideum (Ddi) ddi13598 DDB0230149
Debaryomyces hansenii (Dha) dha3498 DEHA0E05863g
Drosophila melanogaster (Dme) dme7471 CG7977-PA
(FBgn0026372)
Danio rerio (Dre) dre13767 ENSDARP00000006624
(rpl23a)
Q4G0B1
Encephalitozoon cuniculi (Ecu) ecu541 19074625
Encephalitozoon cuniculi (Ecu) ecu346 19173515
Takifugu rubripes (Fru) fru2082 SINFRUP00000128020
Gallus gallus (Gga) gga8893 ENSGALP00000006308
(RPL23A)
Homo sapiens (Hsa) hsa23408 ENSP00000250979
Homo sapiens (Hsa) hsa3029 ENSP00000329503
Homo sapiens (Hsa) hsa15836 ENSP00000339058
Homo sapiens (Hsa) hsa13349 ENSP00000347969
(RPL23A)
C9JSM9
Kluyveromyces lactis (Kla) kla3285 KLLA0E07458g
Mus musculus (Mmu) mmu4317 ENSMUSP00000072118
Mus musculus (Mmu) mmu8532 ENSMUSP00000078397
(MGI:3040672)
P62751
Mus musculus (Mmu) mmu1858 ENSMUSP00000079519
Neurospora crassa (Ncr) ncr6051 NCU06226.2
Oryza sativa (Osa) osa12320 2821.m00166
Oryza sativa (Osa) osa13839 2954.m00175
Oryza sativa (Osa) osa35573 4779.m00183
Oryza sativa (Osa) osa83491 8248.m00180
Oryza sativa (Osa) osa83507 8248.m00226
Plasmodium falciparum (Pfa) pfa4293 PF13_0132
Rattus norvegicus (Rno) rno5617 ENSRNOP00000036391
(RGD:1304897)
P62752
Rattus norvegicus (Rno) rno9250 ENSRNOP00000040232
(GI:688776)
Rattus norvegicus (Rno) rno15483 ENSRNOP00000043004
(RGD:1564606)
Rattus norvegicus (Rno) rno10219 ENSRNOP00000049652
Saccharomyces cerevisiae (Sce) sce5685 YOL127W
(S000005487)
Schizosaccharomyces pombe (Spo) spo1803 SPBC106.18 Q10330
Schizosaccharomyces pombe (Spo) spo2595 SPBC4F6.04 O74391
Yarrowia lipolytica (Yli) yli6411 YALI0F25531g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
MmuMGI:3040672
GO:0005618 cell wall C
IDA
AthAt2g39460
GO:0005622 intracellular C
ISS
AthAt3g55280
At2g39460
GO:0005730 nucleolus C
IDA
AthAt2g39460
GO:0005737 cytoplasm C
IDA
SpoSPBC4F6.04
GO:0005811 lipid particle C
IDA
DmeFBgn0026372
GO:0005829 cytosol C
IDA
SpoSPBC106.18
GO:0015934 large ribosomal subunit C
TAS
AthAt2g39460
GO:0016020 membrane C
IDA
AthAt3g55280
GO:0022625 cytosolic large ribosomal subunit C
IDA
AthAt3g55280
At2g39460
ISS
AthAt2g39460
At3g55280
DmeFBgn0026372
PfaPF13_0132
SpoSPBC106.18
SPBC4F6.04
NAS
DmeFBgn0026372
TAS
SceS000005487
GO:0022626 cytosolic ribosome C
IDA
AthAt3g55280
At2g39460
GO:0003674 molecular_function F
ND
MmuMGI:3040672
GO:0003723 RNA binding F
IDA
SceS000005487
ISS
AthAt3g55280
At2g39460
GO:0003735 structural constituent of ribosome F
ISS
AthAt2g39460
At3g55280
DmeFBgn0026372
SpoSPBC4F6.04
SPBC106.18
NAS
DmeFBgn0026372
TAS
SceS000005487
GO:0019843 rRNA binding F
ISS
PfaPF13_0132
SpoSPBC106.18
GO:0000003 reproduction P
IMP
CelWBGene00004438
WBGene00004439
GO:0000027 ribosomal large subunit assembly P
IMP
SceS000005487
ISS
SpoSPBC106.18
SPBC4F6.04
GO:0002119 nematode larval development P
IMP
CelWBGene00004438
GO:0006412 translation P
ISS
AthAt3g55280
At2g39460
DmeFBgn0026372
SpoSPBC4F6.04
SPBC106.18
NAS
DmeFBgn0026372
TAS
AthAt2g39460
SceS000005487
GO:0006898 receptor-mediated endocytosis P
IMP
CelWBGene00004439
GO:0006979 response to oxidative stress P
IEP
AthAt2g39460
At3g55280
GO:0008150 biological_process P
ND
MmuMGI:3040672
GO:0009409 response to cold P
IEP
AthAt3g55280
At2g39460
GO:0009644 response to high light intensity P
IEP
AthAt2g39460
At3g55280
GO:0009790 embryo development P
IMP
CelWBGene00004439
GO:0009792 embryo development ending in birth or egg
hatching
P
IMP
CelWBGene00004438
WBGene00004439
GO:0016246 RNA interference P
IMP
CelWBGene00004439
GO:0040002 collagen and cuticulin-based cuticle
development
P
IMP
CelWBGene00004439
GO:0040007 growth P
IMP
CelWBGene00004438
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00004439
WBGene00004438
GO:0040018 positive regulation of multicellular organism
growth
P
IMP
CelWBGene00004438
GO:0040035 hermaphrodite genitalia development P
IMP
CelWBGene00004439
WBGene00004438
GO:0042254 ribosome biogenesis P
ISS
AthAt2g39460
At3g55280
SpoSPBC106.18

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Curated yeast ortholog results:

S. pombe
systematic ID
S. cerevisiae
systematic ID
SPBC4F6.04
(O74391)
YOL127W
(S000005487)
SPBC106.18
(Q10330)
YOL127W
(S000005487)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005737 cytoplasm C
IDA
SpoSPBC4F6.04
GO:0005829 cytosol C
IDA
SpoSPBC106.18
GO:0022625 cytosolic large ribosomal subunit C
ISS
SpoSPBC106.18
SPBC4F6.04
TAS
SceS000005487
GO:0003723 RNA binding F
IDA
SceS000005487
GO:0003735 structural constituent of ribosome F
ISS
SpoSPBC4F6.04
SPBC106.18
TAS
SceS000005487
GO:0019843 rRNA binding F
ISS
SpoSPBC106.18
GO:0000027 ribosomal large subunit assembly P
IMP
SceS000005487
ISS
SpoSPBC106.18
SPBC4F6.04
GO:0006412 translation P
ISS
SpoSPBC4F6.04
SPBC106.18
TAS
SceS000005487
GO:0042254 ribosome biogenesis P
ISS
SpoSPBC106.18

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s.khadayate@ucl.ac.uk