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Search term: YOL149W

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name DCP1
SGD link S000005509
Alternative ID YOL149W
Description Subunit of the Dcp1p-Dcp2p decapping enzyme complex, which removes the 5' cap structure from mRNAs prior to their degradation; enhances the activity of catalytic subunit Dcp2p; regulated by DEAD box protein Dhh1p
Synonyms YOL149W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG2868 ACDHYPE

KOGs classification KOGs description
INFORMATION STORAGE AND PROCESSINGINFORMATION STORAGE AND PROCESSING Decapping enzyme complex component DCP1

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At1g08370 GI:18390886
Caenorhabditis elegans (Cel) CE22543
(WBGene00021929)		 GI:17543662 Q9N363
Drosophila melanogaster (Dme) 7291667
(Dcp1)		 GI:20130321 Q9W1H5
Homo sapiens (Hsa) Hs8923767 GI:8923767
Homo sapiens (Hsa) Hs20480089 GI:20480089
Saccharomyces cerevisiae (Sce) YOL149w
(S000005509)		 GI:6324423 Q12517
Schizosaccharomyces pombe (Spo) SPBC3B9.21 GI:19113454 Q9P805
Encephalitozoon cuniculi (Ecu) ECU11g0970 GI:19074897 Q8SU45


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000932 cytoplasmic mRNA processing body C
IDA
AthAt1g08370
CelWBGene00021929
DmeDcp1
SceS000005509
IGI
SpoSPBC3B9.21
IMP
SceS000005509
NAS
AthAt1g08370
GO:0005634 nucleus C
IDA
SpoSPBC3B9.21
GO:0005737 cytoplasm C
IDA
AthAt1g08370
GO:0005829 cytosol C
IDA
SpoSPBC3B9.21
GO:0005845 mRNA cap binding complex C
IDA
SpoSPBC3B9.21
IGI
SpoSPBC3B9.21
GO:0043186 P granule C
IDA
CelWBGene00021929
DmeDcp1
GO:0000340 RNA 7-methylguanosine cap binding F
IGI
SpoSPBC3B9.21
GO:0003729 mRNA binding F
IPI
SceS000005509
GO:0005515 protein binding F
IPI
SpoSPBC3B9.21
GO:0008047 enzyme activator activity F
IDA
SceS000005509
GO:0030234 enzyme regulator activity F
IDA
SpoSPBC3B9.21
GO:0042803 protein homodimerization activity F
IPI
AthAt1g08370
GO:0050072 m7G(5')pppN diphosphatase activity F
IDA
SceS000005509
SpoSPBC3B9.21
IGI
SpoSPBC3B9.21
GO:0000184 nuclear-transcribed mRNA catabolic process,
nonsense-mediated decay		 P
IGI
SpoSPBC3B9.21
GO:0000290 deadenylation-dependent decapping of
nuclear-transcribed mRNA		 P
IDA
SceS000005509
IMP
SpoSPBC3B9.21
GO:0000956 nuclear-transcribed mRNA catabolic
process		 P
IMP
DmeDcp1
GO:0006399 tRNA metabolic process P
RCA
SceS000005509
GO:0006401 RNA catabolic process P
RCA
SceS000005509
GO:0031087 deadenylation-independent decapping of
nuclear-transcribed mRNA		 P
IDA
AthAt1g08370
IMP
SpoSPBC3B9.21
GO:0035195 gene silencing by miRNA P
IMP
DmeDcp1
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00021929
GO:0045451 pole plasm oskar mRNA localization P
IMP
DmeDcp1

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
40175

Species Gene ID NCBI link UniProt link
Saccharomyces cerevisiae (Sce) DCP1
(S000005509)		 GI:6324423 Q12517
Kluyveromyces lactis (Kla) KLLA0E01826g GI:50308059
Eremothecium gossypii (Ego) AGOS_AGR402C GI:45201498


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000932 cytoplasmic mRNA processing body C
IDA
SceS000005509
IMP
SceS000005509
GO:0003729 mRNA binding F
IPI
SceS000005509
GO:0008047 enzyme activator activity F
IDA
SceS000005509
GO:0050072 m7G(5')pppN diphosphatase activity F
IDA
SceS000005509
GO:0000290 deadenylation-dependent decapping of
nuclear-transcribed mRNA		 P
IDA
SceS000005509
GO:0006399 tRNA metabolic process P
RCA
SceS000005509
GO:0006401 RNA catabolic process P
RCA
SceS000005509

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_20656

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Ashbya gossypii (Ago) ago4713 AGR402C
Candida glabrata (Cgl) cgl261 CAGL0B01331g
Debaryomyces hansenii (Dha) dha121 DEHA0A02739g
Kluyveromyces lactis (Kla) kla3029 KLLA0E01826g
Saccharomyces cerevisiae (Sce) sce5707 YOL149W
(S000005509)
Yarrowia lipolytica (Yli) yli6004 YALI0F15719g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000932 cytoplasmic mRNA processing body C
IDA
SceS000005509
IMP
SceS000005509
GO:0003729 mRNA binding F
IPI
SceS000005509
GO:0008047 enzyme activator activity F
IDA
SceS000005509
GO:0050072 m7G(5')pppN diphosphatase activity F
IDA
SceS000005509
GO:0000290 deadenylation-dependent decapping of
nuclear-transcribed mRNA		 P
IDA
SceS000005509
GO:0006399 tRNA metabolic process P
RCA
SceS000005509
GO:0006401 RNA catabolic process P
RCA
SceS000005509

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPBC3B9.21
(Q9P805)		 YOL149W
(S000005509)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000932 cytoplasmic mRNA processing body C
IDA
SceS000005509
IGI
SpoSPBC3B9.21
IMP
SceS000005509
GO:0005634 nucleus C
IDA
SpoSPBC3B9.21
GO:0005829 cytosol C
IDA
SpoSPBC3B9.21
GO:0005845 mRNA cap binding complex C
IDA
SpoSPBC3B9.21
IGI
SpoSPBC3B9.21
GO:0000340 RNA 7-methylguanosine cap binding F
IGI
SpoSPBC3B9.21
GO:0003729 mRNA binding F
IPI
SceS000005509
GO:0005515 protein binding F
IPI
SpoSPBC3B9.21
GO:0008047 enzyme activator activity F
IDA
SceS000005509
GO:0030234 enzyme regulator activity F
IDA
SpoSPBC3B9.21
GO:0050072 m7G(5')pppN diphosphatase activity F
IDA
SceS000005509
SpoSPBC3B9.21
IGI
SpoSPBC3B9.21
GO:0000184 nuclear-transcribed mRNA catabolic process,
nonsense-mediated decay		 P
IGI
SpoSPBC3B9.21
GO:0000290 deadenylation-dependent decapping of
nuclear-transcribed mRNA		 P
IDA
SceS000005509
IMP
SpoSPBC3B9.21
GO:0006399 tRNA metabolic process P
RCA
SceS000005509
GO:0006401 RNA catabolic process P
RCA
SceS000005509
GO:0031087 deadenylation-independent decapping of
nuclear-transcribed mRNA		 P
IMP
SpoSPBC3B9.21

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