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Search term: YOR001W

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name RRP6
SGD link S000005527
Alternative ID YOR001W
Description Nuclear exosome exonuclease component; has 3'-5' exonuclease activity; involved in RNA processing, maturation, surveillance, degradation, tethering, and export; has similarity to E. coli RNase D and to human PM-Sc1 100 (EXOSC10)
Synonyms YOR001W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG2206 ACDHY-E

KOGs classification KOGs description
INFORMATION STORAGE AND PROCESSING Exosome 3'-5' exoribonuclease complex, subunit PM/SCL-100 (Rrp6)

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At1g54440 GI:15221816
Arabidopsis thaliana (Ath) At2g32420 GI:15225242
Arabidopsis thaliana (Ath) At5g35910 GI:15239221
Caenorhabditis elegans (Cel) CE02145
(WBGene00000796)		 GI:17531757 Q17951
Drosophila melanogaster (Dme) 7299933 GI:7299933
Homo sapiens (Hsa) Hs4505917 GI:4505917 Q01780
Saccharomyces cerevisiae (Sce) YOR001w
(S000005527)		 GI:6324574 Q12149
Encephalitozoon cuniculi (Ecu) ECU11g1140 GI:19074914 Q8SU35


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000176 nuclear exosome (RNase complex) C
IDA
SceS000005527
GO:0000178 exosome (RNase complex) C
TAS
CelWBGene00000796
GO:0005622 intracellular C
ISS
AthAt1g54440
At5g35910
GO:0005634 nucleus C
IDA
SceS000005527
GO:0005730 nucleolus C
IDA
SceS000005527
RCA
SceS000005527
GO:0000175 3'-5'-exoribonuclease activity F
IDA
SceS000005527
GO:0003676 nucleic acid binding F
ISS
AthAt5g35910
At1g54440
GO:0004527 exonuclease activity F
ISS
CelWBGene00000796
GO:0008408 3'-5' exonuclease activity F
ISS
AthAt5g35910
At1g54440
GO:0000184 nuclear-transcribed mRNA catabolic process,
nonsense-mediated decay		 P
RCA
SceS000005527
GO:0000291 nuclear-transcribed mRNA catabolic process,
exonucleolytic		 P
RCA
SceS000005527
GO:0000467 exonucleolytic trimming to generate mature 3'-end
of 5.8S rRNA from tricistronic rRNA transcript
(SSU-rRNA, 5.8S rRNA, LSU-rRNA)		 P
IMP
SceS000005527
GO:0000973 posttranscriptional tethering of RNA polymerase II
gene DNA at nuclear periphery		 P
IMP
SceS000005527
GO:0002119 nematode larval development P
IMP
CelWBGene00000796
GO:0006309 DNA fragmentation involved in apoptotic nuclear
change		 P
IGI
CelWBGene00000796
IMP
CelWBGene00000796
GO:0006396 RNA processing P
TAS
CelWBGene00000796
GO:0006898 receptor-mediated endocytosis P
IMP
CelWBGene00000796
GO:0009790 embryo development P
IMP
CelWBGene00000796
GO:0034427 nuclear-transcribed mRNA catabolic process,
exonucleolytic, 3'-5'		 P
RCA
SceS000005527
GO:0034473 U1 snRNA 3'-end processing P
IGI
SceS000005527
IMP
SceS000005527
GO:0034475 U4 snRNA 3'-end processing P
IGI
SceS000005527
IMP
SceS000005527
GO:0034476 U5 snRNA 3'-end processing P
IGI
SceS000005527
IMP
SceS000005527
GO:0040007 growth P
IMP
CelWBGene00000796
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00000796
GO:0043277 apoptotic cell clearance P
IDA
CelWBGene00000796
GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic
process involved in deadenylation-dependent
decay		 P
RCA
SceS000005527
GO:0070478 nuclear-transcribed mRNA catabolic process, 3'-5'
exonucleolytic nonsense-mediated
decay		 P
RCA
SceS000005527
GO:0070481 nuclear-transcribed mRNA catabolic process,
non-stop decay		 P
RCA
SceS000005527
GO:0071033 nuclear retention of pre-mRNA at the site of
transcription		 P
IGI
SceS000005527
GO:0071035 nuclear polyadenylation-dependent rRNA catabolic
process		 P
IGI
SceS000005527
IMP
SceS000005527
GO:0071036 nuclear polyadenylation-dependent snoRNA catabolic
process		 P
IMP
SceS000005527
GO:0071037 nuclear polyadenylation-dependent snRNA catabolic
process		 P
IMP
SceS000005527
GO:0071038 nuclear polyadenylation-dependent tRNA catabolic
process		 P
IDA
SceS000005527
IGI
SceS000005527
GO:0071039 nuclear polyadenylation-dependent CUT catabolic
process		 P
IGI
SceS000005527
IMP
SceS000005527
GO:0071040 nuclear polyadenylation-dependent antisense
transcript catabolic process		 P
IMP
SceS000005527
GO:0071042 nuclear polyadenylation-dependent mRNA catabolic
process		 P
IMP
SceS000005527
GO:0071044 histone mRNA catabolic process P
IMP
SceS000005527
GO:0071049 nuclear retention of pre-mRNA with aberrant
3'-ends at the site of transcription		 P
IGI
SceS000005527
GO:0071051 polyadenylation-dependent snoRNA 3'-end
processing		 P
IMP
SceS000005527

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
117911

Species Gene ID NCBI link UniProt link
Schizosaccharomyces pombe (Spo) rrp6
(SPAC1F3.01)		 GI:63054485 Q10146
Saccharomyces cerevisiae (Sce) RRP6
(S000005527)		 GI:6324574 Q12149
Kluyveromyces lactis (Kla) KLLA0D01309g GI:50306309
Eremothecium gossypii (Ego) AGOS_ACL001C GI:45185687
Magnaporthe grisea (Mgr) MGG_00896 GI:39973915
Neurospora crassa (Ncr) NCU02256.1 GI:32421177


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000176 nuclear exosome (RNase complex) C
IDA
SceS000005527
ISS
SpoSPAC1F3.01
GO:0005634 nucleus C
IDA
SceS000005527
SpoSPAC1F3.01
GO:0005730 nucleolus C
IDA
SceS000005527
SpoSPAC1F3.01
RCA
SceS000005527
GO:0000175 3'-5'-exoribonuclease activity F
IDA
SceS000005527
ISS
SpoSPAC1F3.01
GO:0000184 nuclear-transcribed mRNA catabolic process,
nonsense-mediated decay		 P
RCA
SceS000005527
GO:0000291 nuclear-transcribed mRNA catabolic process,
exonucleolytic		 P
RCA
SceS000005527
GO:0000467 exonucleolytic trimming to generate mature 3'-end
of 5.8S rRNA from tricistronic rRNA transcript
(SSU-rRNA, 5.8S rRNA, LSU-rRNA)		 P
IMP
SceS000005527
GO:0000973 posttranscriptional tethering of RNA polymerase II
gene DNA at nuclear periphery		 P
IMP
SceS000005527
GO:0006364 rRNA processing P
ISS
SpoSPAC1F3.01
GO:0006402 mRNA catabolic process P
ISS
SpoSPAC1F3.01
GO:0034427 nuclear-transcribed mRNA catabolic process,
exonucleolytic, 3'-5'		 P
RCA
SceS000005527
GO:0034473 U1 snRNA 3'-end processing P
IGI
SceS000005527
IMP
SceS000005527
GO:0034475 U4 snRNA 3'-end processing P
IGI
SceS000005527
IMP
SceS000005527
GO:0034476 U5 snRNA 3'-end processing P
IGI
SceS000005527
IMP
SceS000005527
GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic
process involved in deadenylation-dependent
decay		 P
RCA
SceS000005527
GO:0070478 nuclear-transcribed mRNA catabolic process, 3'-5'
exonucleolytic nonsense-mediated
decay		 P
RCA
SceS000005527
GO:0070481 nuclear-transcribed mRNA catabolic process,
non-stop decay		 P
RCA
SceS000005527
GO:0071033 nuclear retention of pre-mRNA at the site of
transcription		 P
IGI
SceS000005527
GO:0071035 nuclear polyadenylation-dependent rRNA catabolic
process		 P
IGI
SceS000005527
IMP
SceS000005527
GO:0071036 nuclear polyadenylation-dependent snoRNA catabolic
process		 P
IMP
SceS000005527
GO:0071037 nuclear polyadenylation-dependent snRNA catabolic
process		 P
IMP
SceS000005527
GO:0071038 nuclear polyadenylation-dependent tRNA catabolic
process		 P
IDA
SceS000005527
IGI
SceS000005527
GO:0071039 nuclear polyadenylation-dependent CUT catabolic
process		 P
IGI
SceS000005527
IMP
SceS000005527
GO:0071040 nuclear polyadenylation-dependent antisense
transcript catabolic process		 P
IMP
SceS000005527
GO:0071042 nuclear polyadenylation-dependent mRNA catabolic
process		 P
IMP
SceS000005527
GO:0071044 histone mRNA catabolic process P
IMP
SceS000005527
GO:0071049 nuclear retention of pre-mRNA with aberrant
3'-ends at the site of transcription		 P
IGI
SceS000005527
GO:0071051 polyadenylation-dependent snoRNA 3'-end
processing		 P
IMP
SceS000005527

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_1214

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga4453 ENSANGP00000020658
Ashbya gossypii (Ago) ago1048 ACL001C
Arabidopsis thaliana (Ath) ath4762 At1g54440.1
Arabidopsis thaliana (Ath) ath25369 At5g35910.1
Caenorhabditis elegans (Cel) cel1929 C14A4.4a
(CE02145;
WBGene00000796)
Caenorhabditis elegans (Cel) cel1930 C14A4.4b
(CE32797)
Candida glabrata (Cgl) cgl1054 CAGL0E02585g
Cryptococcus neoformans (Cne) cne5824 179.m00699
Dictyostelium discoideum (Ddi) ddi2939 DDB0203581
Debaryomyces hansenii (Dha) dha194 DEHA0A04378g
Drosophila melanogaster (Dme) dme12643 CG7292-PA
(FBgn0038269)
Danio rerio (Dre) dre15173 ENSDARP00000018307
Escherichia coli (Eco) eco1760 16129758
Encephalitozoon cuniculi (Ecu) ecu1002 19074914
Takifugu rubripes (Fru) fru17472 SINFRUP00000133183
Gallus gallus (Gga) gga12524 ENSGALP00000004868
Gallus gallus (Gga) gga12525 ENSGALP00000004869
Gallus gallus (Gga) gga12523 ENSGALP00000004870
(EXOSC10)
Homo sapiens (Hsa) hsa265 ENSP00000307307
(EXOSC10)		 Q01780-2
Homo sapiens (Hsa) hsa266 ENSP00000353563
Kluyveromyces lactis (Kla) kla2126 KLLA0D01309g
Mus musculus (Mmu) mmu19436 ENSMUSP00000017408
(MGI:1355322)		 B1ARY9
Mus musculus (Mmu) mmu19437 ENSMUSP00000075401
(MGI:1355322)		 Q8K366
Neurospora crassa (Ncr) ncr2196 NCU02256.2
Oryza sativa (Osa) osa17045 3148.m00123
Oryza sativa (Osa) osa39567 4996.m00054
Oryza sativa (Osa) osa50885 5862.m00107
Plasmodium falciparum (Pfa) pfa1153 PF14_0473
Rattus norvegicus (Rno) rno24419 ENSRNOP00000014593
Rattus norvegicus (Rno) rno24418 ENSRNOP00000014629
Saccharomyces cerevisiae (Sce) sce5729 YOR001W
(S000005527)
Schizosaccharomyces pombe (Spo) spo3913 SPAC1F3.01 Q10146
Yarrowia lipolytica (Yli) yli4045 YALI0E04444g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000176 nuclear exosome (RNase complex) C
IDA
SceS000005527
IPI
DmeFBgn0038269
ISS
DmeFBgn0038269
SpoSPAC1F3.01
GO:0000178 exosome (RNase complex) C
TAS
CelWBGene00000796
GO:0005622 intracellular C
ISS
AthAt1g54440
At5g35910
GO:0005634 nucleus C
IDA
DmeFBgn0038269
SceS000005527
SpoSPAC1F3.01
GO:0005652 nuclear lamina C
IDA
DmeFBgn0038269
GO:0005730 nucleolus C
IDA
DmeFBgn0038269
SceS000005527
SpoSPAC1F3.01
RCA
SceS000005527
TAS
MmuMGI:1355322
GO:0000175 3'-5'-exoribonuclease activity F
IDA
SceS000005527
ISS
SpoSPAC1F3.01
GO:0003674 molecular_function F
ND
MmuMGI:1355322
GO:0003676 nucleic acid binding F
ISS
AthAt5g35910
At1g54440
GO:0004527 exonuclease activity F
ISS
CelWBGene00000796
GO:0008408 3'-5' exonuclease activity F
ISS
AthAt5g35910
At1g54440
GO:0000184 nuclear-transcribed mRNA catabolic process,
nonsense-mediated decay		 P
RCA
SceS000005527
GO:0000291 nuclear-transcribed mRNA catabolic process,
exonucleolytic		 P
RCA
SceS000005527
GO:0000467 exonucleolytic trimming to generate mature 3'-end
of 5.8S rRNA from tricistronic rRNA transcript
(SSU-rRNA, 5.8S rRNA, LSU-rRNA)		 P
IMP
SceS000005527
GO:0000973 posttranscriptional tethering of RNA polymerase II
gene DNA at nuclear periphery		 P
IMP
SceS000005527
GO:0002119 nematode larval development P
IMP
CelWBGene00000796
GO:0006309 DNA fragmentation involved in apoptotic nuclear
change		 P
IGI
CelWBGene00000796
IMP
CelWBGene00000796
GO:0006364 rRNA processing P
ISS
SpoSPAC1F3.01
GO:0006378 mRNA polyadenylation P
IMP
DmeFBgn0038269
GO:0006396 RNA processing P
TAS
CelWBGene00000796
GO:0006402 mRNA catabolic process P
ISS
SpoSPAC1F3.01
GO:0006898 receptor-mediated endocytosis P
IMP
CelWBGene00000796
GO:0008150 biological_process P
ND
MmuMGI:1355322
GO:0009790 embryo development P
IMP
CelWBGene00000796
GO:0034427 nuclear-transcribed mRNA catabolic process,
exonucleolytic, 3'-5'		 P
RCA
SceS000005527
GO:0034473 U1 snRNA 3'-end processing P
IGI
SceS000005527
IMP
SceS000005527
GO:0034475 U4 snRNA 3'-end processing P
IGI
SceS000005527
IMP
SceS000005527
GO:0034476 U5 snRNA 3'-end processing P
IGI
SceS000005527
IMP
SceS000005527
GO:0040007 growth P
IMP
CelWBGene00000796
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00000796
GO:0043277 apoptotic cell clearance P
IDA
CelWBGene00000796
GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic
process involved in deadenylation-dependent
decay		 P
RCA
SceS000005527
GO:0070478 nuclear-transcribed mRNA catabolic process, 3'-5'
exonucleolytic nonsense-mediated
decay		 P
RCA
SceS000005527
GO:0070481 nuclear-transcribed mRNA catabolic process,
non-stop decay		 P
RCA
SceS000005527
GO:0071033 nuclear retention of pre-mRNA at the site of
transcription		 P
IGI
SceS000005527
GO:0071035 nuclear polyadenylation-dependent rRNA catabolic
process		 P
IGI
SceS000005527
IMP
SceS000005527
GO:0071036 nuclear polyadenylation-dependent snoRNA catabolic
process		 P
IMP
SceS000005527
GO:0071037 nuclear polyadenylation-dependent snRNA catabolic
process		 P
IMP
SceS000005527
GO:0071038 nuclear polyadenylation-dependent tRNA catabolic
process		 P
IDA
SceS000005527
IGI
SceS000005527
GO:0071039 nuclear polyadenylation-dependent CUT catabolic
process		 P
IGI
SceS000005527
IMP
SceS000005527
GO:0071040 nuclear polyadenylation-dependent antisense
transcript catabolic process		 P
IMP
SceS000005527
GO:0071042 nuclear polyadenylation-dependent mRNA catabolic
process		 P
IMP
SceS000005527
GO:0071044 histone mRNA catabolic process P
IMP
SceS000005527
GO:0071049 nuclear retention of pre-mRNA with aberrant
3'-ends at the site of transcription		 P
IGI
SceS000005527
GO:0071051 polyadenylation-dependent snoRNA 3'-end
processing		 P
IMP
SceS000005527

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPAC1F3.01
(Q10146)		 YOR001W
(S000005527)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000176 nuclear exosome (RNase complex) C
IDA
SceS000005527
ISS
SpoSPAC1F3.01
GO:0005634 nucleus C
IDA
SceS000005527
SpoSPAC1F3.01
GO:0005730 nucleolus C
IDA
SceS000005527
SpoSPAC1F3.01
RCA
SceS000005527
GO:0000175 3'-5'-exoribonuclease activity F
IDA
SceS000005527
ISS
SpoSPAC1F3.01
GO:0000184 nuclear-transcribed mRNA catabolic process,
nonsense-mediated decay		 P
RCA
SceS000005527
GO:0000291 nuclear-transcribed mRNA catabolic process,
exonucleolytic		 P
RCA
SceS000005527
GO:0000467 exonucleolytic trimming to generate mature 3'-end
of 5.8S rRNA from tricistronic rRNA transcript
(SSU-rRNA, 5.8S rRNA, LSU-rRNA)		 P
IMP
SceS000005527
GO:0000973 posttranscriptional tethering of RNA polymerase II
gene DNA at nuclear periphery		 P
IMP
SceS000005527
GO:0006364 rRNA processing P
ISS
SpoSPAC1F3.01
GO:0006402 mRNA catabolic process P
ISS
SpoSPAC1F3.01
GO:0034427 nuclear-transcribed mRNA catabolic process,
exonucleolytic, 3'-5'		 P
RCA
SceS000005527
GO:0034473 U1 snRNA 3'-end processing P
IGI
SceS000005527
IMP
SceS000005527
GO:0034475 U4 snRNA 3'-end processing P
IGI
SceS000005527
IMP
SceS000005527
GO:0034476 U5 snRNA 3'-end processing P
IGI
SceS000005527
IMP
SceS000005527
GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic
process involved in deadenylation-dependent
decay		 P
RCA
SceS000005527
GO:0070478 nuclear-transcribed mRNA catabolic process, 3'-5'
exonucleolytic nonsense-mediated
decay		 P
RCA
SceS000005527
GO:0070481 nuclear-transcribed mRNA catabolic process,
non-stop decay		 P
RCA
SceS000005527
GO:0071033 nuclear retention of pre-mRNA at the site of
transcription		 P
IGI
SceS000005527
GO:0071035 nuclear polyadenylation-dependent rRNA catabolic
process		 P
IGI
SceS000005527
IMP
SceS000005527
GO:0071036 nuclear polyadenylation-dependent snoRNA catabolic
process		 P
IMP
SceS000005527
GO:0071037 nuclear polyadenylation-dependent snRNA catabolic
process		 P
IMP
SceS000005527
GO:0071038 nuclear polyadenylation-dependent tRNA catabolic
process		 P
IDA
SceS000005527
IGI
SceS000005527
GO:0071039 nuclear polyadenylation-dependent CUT catabolic
process		 P
IGI
SceS000005527
IMP
SceS000005527
GO:0071040 nuclear polyadenylation-dependent antisense
transcript catabolic process		 P
IMP
SceS000005527
GO:0071042 nuclear polyadenylation-dependent mRNA catabolic
process		 P
IMP
SceS000005527
GO:0071044 histone mRNA catabolic process P
IMP
SceS000005527
GO:0071049 nuclear retention of pre-mRNA with aberrant
3'-ends at the site of transcription		 P
IGI
SceS000005527
GO:0071051 polyadenylation-dependent snoRNA 3'-end
processing		 P
IMP
SceS000005527

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Search for gene by ID or name:

Query species:

Include wild-cards:   

Search for GO info:  

GO info in one table:

s.khadayate@ucl.ac.uk