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Search term: YOR018W

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name ROD1
SGD link S000005544
Alternative ID YOR018W
Description Membrane protein that binds the ubiquitin ligase Rsp5p via its 2 PY motifs; overexpression confers resistance to the GST substrate o-dinitrobenzene,zinc, and calcium; proposed to regulate the endocytosis of plasma membrane proteins
Synonyms YOR018W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG3780 -CDHYP-

KOGs classification KOGs description
POORLY CHARACTERIZED Thioredoxin binding protein TBP-2/VDUP1

Species KOG link NCBI link UniProt link
Caenorhabditis elegans (Cel) CE00440
(WBGene00014033)		 GI:17557017 P30647
Caenorhabditis elegans (Cel) CE02397
(WBGene00014159)		 GI:17537991 Q23672
Caenorhabditis elegans (Cel) CE02399
(WBGene00014161)		 GI:17537995 Q23674
Caenorhabditis elegans (Cel) CE02867 GI:17569667
Caenorhabditis elegans (Cel) CE03839
(WBGene00014163)		 GI:17537999 Q23676
Caenorhabditis elegans (Cel) CE05210
(WBGene00007296)		 GI:17550124 Q17624
Caenorhabditis elegans (Cel) CE05847
(WBGene00009579)		 GI:17533841 Q20232
Caenorhabditis elegans (Cel) CE05894 GI:17567925
Caenorhabditis elegans (Cel) CE09936
(WBGene00018060)		 GI:17560588 Q9GYT5
Caenorhabditis elegans (Cel) CE09937
(WBGene00018061)		 GI:17560590 Q9GYT4
Caenorhabditis elegans (Cel) CE12460 GI:17535237
Caenorhabditis elegans (Cel) CE13790
(WBGene00020612)		 GI:17564490 P91469
Caenorhabditis elegans (Cel) CE15846
(WBGene00008843)		 GI:17533237 O17812
Caenorhabditis elegans (Cel) CE16299 GI:17535495
Caenorhabditis elegans (Cel) CE16300
(WBGene00011053)		 GI:17535497 O17984
Caenorhabditis elegans (Cel) CE16301
(WBGene00011054)		 GI:17535499 O17982
Caenorhabditis elegans (Cel) CE16302
(WBGene00011055)		 GI:17535501 O17983
Caenorhabditis elegans (Cel) CE16401 GI:17555050
Caenorhabditis elegans (Cel) CE16825 GI:17557620
Caenorhabditis elegans (Cel) CE17926 GI:17534541
Caenorhabditis elegans (Cel) CE18191 GI:17535963
Caenorhabditis elegans (Cel) CE19045 GI:17536937
Caenorhabditis elegans (Cel) CE19048
(WBGene00012467)		 GI:17536943 Q9XXI0
Caenorhabditis elegans (Cel) CE19214
(WBGene00013086)		 GI:17537325 Q9XXC4
Caenorhabditis elegans (Cel) CE22239 GI:17556078
Caenorhabditis elegans (Cel) CE29559 GI:17557618
Drosophila melanogaster (Dme) 7291921 GI:7291921 Q0E8K8
Drosophila melanogaster (Dme) 7298868 GI:7298868
Drosophila melanogaster (Dme) 7298941 GI:7298941
Drosophila melanogaster (Dme) 7298942 GI:7298942 Q9VI00
Drosophila melanogaster (Dme) 7298943 GI:7298943 Q9VHZ9
Drosophila melanogaster (Dme) 7298944 GI:7298944 Q9VHZ8
Drosophila melanogaster (Dme) 7298945 GI:7298945
Drosophila melanogaster (Dme) 7299386 GI:7299386 Q9VGU7
Drosophila melanogaster (Dme) 7299389 GI:7299389
Homo sapiens (Hsa) Hs17468049 GI:17468049
Homo sapiens (Hsa) Hs17483233 GI:17483233
Homo sapiens (Hsa) Hs18373305
(ARRDC2)		 GI:18373305 Q8TBH0
Homo sapiens (Hsa) Hs20543322 GI:20543322
Homo sapiens (Hsa) Hs22054101 GI:22054101
Homo sapiens (Hsa) Hs22057968 GI:22057968
Homo sapiens (Hsa) Hs7949163 GI:7949163
Saccharomyces cerevisiae (Sce) YBL101c
(S000000197)		 GI:6319367 P38167
Saccharomyces cerevisiae (Sce) YFR022w
(S000001918)		 GI:14318544 P43602
Saccharomyces cerevisiae (Sce) YGR068c
(S000003300)		 GI:6321506 P53244
Saccharomyces cerevisiae (Sce) YJL084c
(S000003620)		 GI:6322377 P47029
Saccharomyces cerevisiae (Sce) YKR021w
(S000001729)		 GI:6322873 P36117
Saccharomyces cerevisiae (Sce) YOR018w
(S000005544)		 GI:6324592 Q02805
Saccharomyces cerevisiae (Sce) YPR030w
(S000006234)		 GI:6325287 Q12734
Schizosaccharomyces pombe (Spo) SPAC31A2.12 GI:19113836 Q09729
Schizosaccharomyces pombe (Spo) SPBC2D10.04 GI:19113015 O74798
Schizosaccharomyces pombe (Spo) SPBC839.02 GI:19112034 Q8WZK5
Schizosaccharomyces pombe (Spo) SPCC584.15c GI:19075720 Q09889


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
SceS000003300
S000001918
GO:0005634 nucleus C
IDA
SceS000006234
GO:0005737 cytoplasm C
IDA
SceS000001729
S000000197
S000003620
SpoSPBC2D10.04
ISS
SpoSPBC2D10.04
SPBC839.02
GO:0005829 cytosol C
IDA
SpoSPAC31A2.12
SPBC2D10.04
SPCC584.15c
GO:0005886 plasma membrane C
IDA
SceS000005544
GO:0032153 cell division site C
IDA
SpoSPCC584.15c
SPBC2D10.04
GO:0051286 cell tip C
IDA
SpoSPBC2D10.04
GO:0005509 calcium ion binding F
ISS
SpoSPAC31A2.12
SPBC2D10.04
SPBC839.02
SPCC584.15c
GO:0031625 ubiquitin protein ligase binding F
IPI
SceS000003620
S000001729
S000001918
S000000197
S000003300
S000005544
S000006234
GO:0006357 regulation of transcription from RNA polymerase II
promoter		 P
IGI
SceS000006234
IMP
SceS000006234
GO:0007039 vacuolar protein catabolic process P
RCA
SceS000000197
GO:0007165 signal transduction P
NAS
SpoSPBC2D10.04
SPBC839.02
GO:0009966 regulation of signal transduction P
ISS
SpoSPAC31A2.12
SPCC584.15c
GO:0030435 sporulation resulting in formation of a cellular
spore		 P
RCA
SceS000006234
GO:0031505 fungal-type cell wall organization P
IGI
SceS000006234
IMP
SceS000000197
GO:0033554 cellular response to stress P
IEP
SpoSPAC31A2.12
GO:0042493 response to drug P
IMP
SceS000005544
GO:0051049 regulation of transport P
RCA
SceS000001918
GO:0051130 positive regulation of cellular component
organization		 P
RCA
SceS000001918
GO:0070086 ubiquitin-dependent endocytosis P
IMP
SceS000000197
IPI
SceS000000197
ISA
SceS000001729
S000006234
S000003300
S000005544
S000003620
S000001918
ISS
SpoSPBC2D10.04
SPBC839.02

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
40232

Species Gene ID NCBI link UniProt link
Saccharomyces cerevisiae (Sce) ROD1
(S000005544)		 GI:6324592 Q02805
Kluyveromyces lactis (Kla) KLLA0D04708g GI:50306593
Eremothecium gossypii (Ego) AGOS_ADR172C GI:45188046
Magnaporthe grisea (Mgr) MGG_01045 GI:39973617
Neurospora crassa (Ncr) NCU03887.1 GI:32405186


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005886 plasma membrane C
IDA
SceS000005544
GO:0031625 ubiquitin protein ligase binding F
IPI
SceS000005544
GO:0042493 response to drug P
IMP
SceS000005544
GO:0070086 ubiquitin-dependent endocytosis P
ISA
SceS000005544

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_8580

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Ashbya gossypii (Ago) ago1914 ADR172C
Caenorhabditis elegans (Cel) cel999 C04E12.11
(CE35220;
WBGene00015440)
Candida glabrata (Cgl) cgl81 CAGL0A02046g
Candida glabrata (Cgl) cgl3979 CAGL0K10714g
Cryptococcus neoformans (Cne) cne5839 179.m00715
Debaryomyces hansenii (Dha) dha6134 DEHA0G09746g
Drosophila melanogaster (Dme) dme11411 CG18744-PA
(FBgn0042101)
Kluyveromyces lactis (Kla) kla2269 KLLA0D04708g
Neurospora crassa (Ncr) ncr3776 NCU03887.2
Saccharomyces cerevisiae (Sce) sce2048 YFR022W
(S000001918)
Saccharomyces cerevisiae (Sce) sce5749 YOR018W
(S000005544)
Schizosaccharomyces pombe (Spo) spo225 SPAC31A2.12 Q09729
Yarrowia lipolytica (Yli) yli3253 YALI0D12969g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
SceS000001918
GO:0005829 cytosol C
IDA
SpoSPAC31A2.12
GO:0005886 plasma membrane C
IDA
SceS000005544
GO:0005509 calcium ion binding F
ISS
SpoSPAC31A2.12
GO:0031625 ubiquitin protein ligase binding F
IPI
SceS000001918
S000005544
GO:0009966 regulation of signal transduction P
ISS
SpoSPAC31A2.12
GO:0033554 cellular response to stress P
IEP
SpoSPAC31A2.12
GO:0042493 response to drug P
IMP
SceS000005544
GO:0051049 regulation of transport P
RCA
SceS000001918
GO:0051130 positive regulation of cellular component
organization		 P
RCA
SceS000001918
GO:0070086 ubiquitin-dependent endocytosis P
ISA
SceS000005544
S000001918

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPCC584.15c
(Q09889)		 YOR018W
(S000005544)
SPAC31A2.12
(Q09729)		 YOR018W
(S000005544)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005829 cytosol C
IDA
SpoSPAC31A2.12
SPCC584.15c
GO:0005886 plasma membrane C
IDA
SceS000005544
GO:0032153 cell division site C
IDA
SpoSPCC584.15c
GO:0005509 calcium ion binding F
ISS
SpoSPAC31A2.12
SPCC584.15c
GO:0031625 ubiquitin protein ligase binding F
IPI
SceS000005544
GO:0009966 regulation of signal transduction P
ISS
SpoSPAC31A2.12
SPCC584.15c
GO:0033554 cellular response to stress P
IEP
SpoSPAC31A2.12
GO:0042493 response to drug P
IMP
SceS000005544
GO:0070086 ubiquitin-dependent endocytosis P
ISA
SceS000005544

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s.khadayate@ucl.ac.uk