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Search term: YOR035C


Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name SHE4
SGD link S000005561
Alternative ID YOR035C
Description Protein containing a UCS (UNC-45/CRO1/SHE4) domain, binds to myosin motor domains to regulate myosin function; involved in endocytosis, polarization of the actin cytoskeleton, and asymmetric mRNA localization
Synonyms YOR035C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG4151 ACDHYP-

KOGs classification KOGs description
CELLULAR PROCESSES AND SIGNALINGCELLULAR PROCESSES AND SIGNALINGPOORLY CHARACTERIZED Myosin assembly protein/sexual cycle protein and related proteins

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At1g62390 GI:18407574
Arabidopsis thaliana (Ath) At2g25290 GI:15224702
Arabidopsis thaliana (Ath) At4g32070 GI:15236655
Arabidopsis thaliana (Ath) At5g20360 GI:15241328
Caenorhabditis elegans (Cel) CE01925
(WBGene00006781)
GI:17555404 Q09981
Drosophila melanogaster (Dme) 7298982
(FBgn0010812)
GI:17864418 Q9VHW4
Homo sapiens (Hsa) Hs18587044 GI:18587044
Homo sapiens (Hsa) Hs8923821 GI:8923821
Saccharomyces cerevisiae (Sce) YOR035c
(S000005561)
GI:6324609 P51534
Schizosaccharomyces pombe (Spo) SPCC613.04c GI:19075192 O74994


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
AthAt2g25290
At5g20360
GO:0005634 nucleus C
IDA
SpoSPCC613.04c
GO:0005737 cytoplasm C
IDA
SceS000005561
GO:0005742 mitochondrial outer membrane translocase
complex
C
ISS
DmeFBgn0010812
GO:0005773 vacuole C
IDA
AthAt4g32070
GO:0005826 actomyosin contractile ring C
IDA
SpoSPCC613.04c
GO:0005829 cytosol C
IDA
SpoSPCC613.04c
GO:0005884 actin filament C
IDA
SpoSPCC613.04c
GO:0005886 plasma membrane C
IDA
CelWBGene00006781
GO:0005938 cell cortex C
IDA
CelWBGene00006781
GO:0032154 cleavage furrow C
IDA
CelWBGene00006781
GO:0003729 mRNA binding F
IDA
SpoSPCC613.04c
GO:0005515 protein binding F
IPI
SpoSPCC613.04c
GO:0017022 myosin binding F
IDA
SceS000005561
ISS
SpoSPCC613.04c
GO:0031625 ubiquitin protein ligase binding F
IPI
CelWBGene00006781
GO:0000003 reproduction P
IMP
CelWBGene00006781
GO:0000915 cytokinesis, actomyosin contractile ring
assembly
P
IMP
SpoSPCC613.04c
GO:0006898 receptor-mediated endocytosis P
IMP
CelWBGene00006781
GO:0006914 autophagy P
RCA
SceS000005561
GO:0007047 cellular cell wall organization P
RCA
SceS000005561
GO:0007533 mating type switching P
IMP
SceS000005561
GO:0008150 biological_process P
ND
AthAt5g20360
At2g25290
At4g32070
GO:0008298 intracellular mRNA localization P
IMP
SceS000005561
RCA
SceS000005561
GO:0009792 embryo development ending in birth or egg
hatching
P
IMP
CelWBGene00006781
GO:0018991 oviposition P
IGI
CelWBGene00006781
IMP
CelWBGene00006781
GO:0030036 actin cytoskeleton organization P
TAS
SceS000005561
GO:0030435 sporulation resulting in formation of a cellular
spore
P
RCA
SceS000005561
GO:0034613 cellular protein localization P
IGI
SpoSPCC613.04c
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00006781
GO:0040011 locomotion P
IGI
CelWBGene00006781
IMP
CelWBGene00006781
GO:0040017 positive regulation of locomotion P
IMP
CelWBGene00006781
GO:0045214 sarcomere organization P
IGI
CelWBGene00006781
IMP
CelWBGene00006781
GO:0048308 organelle inheritance P
RCA
SceS000005561
GO:0051083 'de novo' cotranslational protein
folding
P
IPI
SpoSPCC613.04c

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
74818

Species Gene ID NCBI link UniProt link
Saccharomyces cerevisiae (Sce) SHE4
(S000005561)
GI:6324609 P51534
Kluyveromyces lactis (Kla) KLLA0E16742g GI:50309389


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005737 cytoplasm C
IDA
SceS000005561
GO:0017022 myosin binding F
IDA
SceS000005561
GO:0006914 autophagy P
RCA
SceS000005561
GO:0007047 cellular cell wall organization P
RCA
SceS000005561
GO:0007533 mating type switching P
IMP
SceS000005561
GO:0008298 intracellular mRNA localization P
IMP
SceS000005561
RCA
SceS000005561
GO:0030036 actin cytoskeleton organization P
TAS
SceS000005561
GO:0030435 sporulation resulting in formation of a cellular
spore
P
RCA
SceS000005561
GO:0048308 organelle inheritance P
RCA
SceS000005561

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_24692

Species OrthoMCL
sequence
Model organism
protein page
UniProt link
Ashbya gossypii (Ago) ago2889 AER389C
Candida glabrata (Cgl) cgl2570 CAGL0I01034g
Debaryomyces hansenii (Dha) dha4207 DEHA0E21934g
Kluyveromyces lactis (Kla) kla3701 KLLA0E16742g
Saccharomyces cerevisiae (Sce) sce5769 YOR035C
(S000005561)


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005737 cytoplasm C
IDA
SceS000005561
GO:0017022 myosin binding F
IDA
SceS000005561
GO:0006914 autophagy P
RCA
SceS000005561
GO:0007047 cellular cell wall organization P
RCA
SceS000005561
GO:0007533 mating type switching P
IMP
SceS000005561
GO:0008298 intracellular mRNA localization P
IMP
SceS000005561
RCA
SceS000005561
GO:0030036 actin cytoskeleton organization P
TAS
SceS000005561
GO:0030435 sporulation resulting in formation of a cellular
spore
P
RCA
SceS000005561
GO:0048308 organelle inheritance P
RCA
SceS000005561

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Curated yeast ortholog results:

S. pombe
systematic ID
S. cerevisiae
systematic ID
SPCC613.04c
(O74994)
YOR035C
(S000005561)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SpoSPCC613.04c
GO:0005737 cytoplasm C
IDA
SceS000005561
GO:0005826 actomyosin contractile ring C
IDA
SpoSPCC613.04c
GO:0005829 cytosol C
IDA
SpoSPCC613.04c
GO:0005884 actin filament C
IDA
SpoSPCC613.04c
GO:0003729 mRNA binding F
IDA
SpoSPCC613.04c
GO:0005515 protein binding F
IPI
SpoSPCC613.04c
GO:0017022 myosin binding F
IDA
SceS000005561
ISS
SpoSPCC613.04c
GO:0000915 cytokinesis, actomyosin contractile ring
assembly
P
IMP
SpoSPCC613.04c
GO:0006914 autophagy P
RCA
SceS000005561
GO:0007047 cellular cell wall organization P
RCA
SceS000005561
GO:0007533 mating type switching P
IMP
SceS000005561
GO:0008298 intracellular mRNA localization P
IMP
SceS000005561
RCA
SceS000005561
GO:0030036 actin cytoskeleton organization P
TAS
SceS000005561
GO:0030435 sporulation resulting in formation of a cellular
spore
P
RCA
SceS000005561
GO:0034613 cellular protein localization P
IGI
SpoSPCC613.04c
GO:0048308 organelle inheritance P
RCA
SceS000005561
GO:0051083 'de novo' cotranslational protein
folding
P
IPI
SpoSPCC613.04c

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GO info in one table:

s.khadayate@ucl.ac.uk