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Search term: YOR061W

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name CKA2
SGD link S000005587
Alternative ID YOR061W
Description Alpha' catalytic subunit of casein kinase 2, a Ser/Thr protein kinase with roles in cell growth and proliferation; the holoenzyme also contains CKA1, CKB1 and CKB2, the many substrates include transcription factors and all RNA polymerases
Synonyms YOR061W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG0668 ACDHYPE

KOGs classification KOGs description
CELLULAR PROCESSES AND SIGNALINGCELLULAR PROCESSES AND SIGNALINGINFORMATION STORAGE AND PROCESSING Casein kinase II, alpha subunit

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At2g23070 GI:15227778
Arabidopsis thaliana (Ath) At2g23080 GI:15227779
Arabidopsis thaliana (Ath) At3g50000 GI:15229650
Arabidopsis thaliana (Ath) At5g67380 GI:15240716
Caenorhabditis elegans (Cel) CE17321
(WBGene00002191)		 GI:17505290 P18334
Drosophila melanogaster (Dme) 7289745 GI:17864602 A4V2B8
Homo sapiens (Hsa) Hs4503095 GI:4503095 P68400
Homo sapiens (Hsa) Hs4503097
(CSNK2A2)		 GI:4503097 P19784
Saccharomyces cerevisiae (Sce) YIL035c
(S000001297)		 GI:6322154 P15790
Saccharomyces cerevisiae (Sce) YOR061w
(S000005587)		 GI:6324635 P19454
Schizosaccharomyces pombe (Spo) SPAC23C11.11 GI:19114554 P40231
Encephalitozoon cuniculi (Ecu) ECU05g1510 GI:19173691 Q8SRU0
Arabidopsis thaliana (Ath) At2g23070 GI:15227778
Arabidopsis thaliana (Ath) At2g23080 GI:15227779
Arabidopsis thaliana (Ath) At3g50000 GI:15229650
Arabidopsis thaliana (Ath) At5g67380 GI:15240716
Caenorhabditis elegans (Cel) CE17321
(WBGene00002191)		 GI:17505290 P18334
Drosophila melanogaster (Dme) 7289745 GI:17864602 A4V2B8
Homo sapiens (Hsa) Hs4503095 GI:4503095 P68400
Homo sapiens (Hsa) Hs4503097
(CSNK2A2)		 GI:4503097 P19784
Saccharomyces cerevisiae (Sce) YIL035c
(S000001297)		 GI:6322154 P15790
Saccharomyces cerevisiae (Sce) YOR061w
(S000005587)		 GI:6324635 P19454
Schizosaccharomyces pombe (Spo) SPAC23C11.11 GI:19114554 P40231
Encephalitozoon cuniculi (Ecu) ECU05g1510 GI:19173691 Q8SRU0


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
AthAt2g23080
GO:0005634 nucleus C
IDA
SpoSPAC23C11.11
GO:0005654 nucleoplasm C
RCA
SceS000001297
GO:0005730 nucleolus C
IDA
SpoSPAC23C11.11
GO:0005829 cytosol C
IDA
SpoSPAC23C11.11
GO:0005886 plasma membrane C
IDA
AthAt3g50000
GO:0005956 protein kinase CK2 complex C
IDA
SceS000005587
S000001297
TAS
SpoSPAC23C11.11
GO:0031931 TORC1 complex C
IDA
SpoSPAC23C11.11
GO:0031932 TORC2 complex C
IDA
SpoSPAC23C11.11
GO:0034456 UTP-C complex C
IDA
SceS000001297
S000005587
GO:0004674 protein serine/threonine kinase
activity		 F
IDA
SceS000001297
S000005587
ISS
SpoSPAC23C11.11
GO:0005515 protein binding F
IPI
AthAt3g50000
HsaCSNK2A2
GO:0005524 ATP binding F
ISS
SpoSPAC23C11.11
GO:0016301 kinase activity F
IDA
AthAt3g50000
At5g67380
ISS
AthAt3g50000
At5g67380
At2g23070
At2g23080
GO:0030234 enzyme regulator activity F
RCA
SceS000001297
GO:0047485 protein N-terminus binding F
IPI
HsaCSNK2A2
GO:0000003 reproduction P
IMP
CelWBGene00002191
GO:0006356 regulation of transcription from RNA polymerase I
promoter		 P
IDA
SceS000001297
S000005587
GO:0006359 regulation of transcription from RNA polymerase
III promoter		 P
IDA
SceS000001297
S000005587
GO:0006468 protein amino acid phosphorylation P
IC
SpoSPAC23C11.11
IDA
SceS000005587
S000001297
IMP
SceS000001297
GO:0006974 response to DNA damage stimulus P
IDA
SceS000001297
S000005587
GO:0007163 establishment or maintenance of cell
polarity		 P
IMP
SpoSPAC23C11.11
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00002191
GO:0031929 TOR signaling cascade P
TAS
SpoSPAC23C11.11
GO:0034606 response to hermaphrodite contact P
IMP
CelWBGene00002191
GO:0034608 vulval location P
IMP
CelWBGene00002191
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00002191
GO:0040035 hermaphrodite genitalia development P
IMP
CelWBGene00002191

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
90874

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) CSNK2A1 GI:29570791
Canis familiaris (Cfa) CSNK2A1 GI:73991511
Rattus norvegicus (Rno) Csnk2a1
(RGD:621663)		 GI:16758674
Gallus gallus (Gga) CSNK2A1 GI:50355952
Caenorhabditis elegans (Cel) kin-3
(CE17321;
WBGene00002191)		 GI:17505290 P18334
Schizosaccharomyces pombe (Spo) cka1
(SPAC23C11.11)		 GI:19114554 P40231
Saccharomyces cerevisiae (Sce) CKA2
(S000005587)		 GI:6324635 P19454
Kluyveromyces lactis (Kla) KLLA0F16467g GI:50311589
Eremothecium gossypii (Ego) AGOS_ADR204W GI:45188077
Magnaporthe grisea (Mgr) MGG_03696 GI:39943232
Neurospora crassa (Ncr) NCU03124.1 GI:32420233
Arabidopsis thaliana (Ath) AT2G23070 GI:15227778


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SpoSPAC23C11.11
TAS
HsaCSNK2A1
GO:0005730 nucleolus C
IDA
SpoSPAC23C11.11
GO:0005829 cytosol C
IDA
SpoSPAC23C11.11
GO:0005886 plasma membrane C
TAS
HsaCSNK2A1
GO:0005956 protein kinase CK2 complex C
IDA
SceS000005587
TAS
SpoSPAC23C11.11
GO:0016580 Sin3 complex C
IDA
HsaCSNK2A1
GO:0016581 NuRD complex C
IDA
HsaCSNK2A1
GO:0031931 TORC1 complex C
IDA
SpoSPAC23C11.11
GO:0031932 TORC2 complex C
IDA
SpoSPAC23C11.11
GO:0034456 UTP-C complex C
IDA
SceS000005587
GO:0004674 protein serine/threonine kinase
activity		 F
IDA
SceS000005587
ISS
SpoSPAC23C11.11
TAS
HsaCSNK2A1
GO:0005515 protein binding F
IPI
HsaCSNK2A1
GO:0005524 ATP binding F
ISS
SpoSPAC23C11.11
GO:0016301 kinase activity F
ISS
AthAt2g23070
GO:0047485 protein N-terminus binding F
IPI
HsaCSNK2A1
GO:0000003 reproduction P
IMP
CelWBGene00002191
GO:0006356 regulation of transcription from RNA polymerase I
promoter		 P
IDA
SceS000005587
GO:0006359 regulation of transcription from RNA polymerase
III promoter		 P
IDA
SceS000005587
GO:0006468 protein amino acid phosphorylation P
IC
SpoSPAC23C11.11
IDA
SceS000005587
GO:0006974 response to DNA damage stimulus P
IDA
SceS000005587
GO:0007163 establishment or maintenance of cell
polarity		 P
IMP
SpoSPAC23C11.11
GO:0007165 signal transduction P
TAS
HsaCSNK2A1
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00002191
GO:0031929 TOR signaling cascade P
TAS
SpoSPAC23C11.11
GO:0034606 response to hermaphrodite contact P
IMP
CelWBGene00002191
GO:0034608 vulval location P
IMP
CelWBGene00002191
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00002191
GO:0040035 hermaphrodite genitalia development P
IMP
CelWBGene00002191

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_730

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga986 ENSANGP00000017774
Ashbya gossypii (Ago) ago1639 ADL102C
Ashbya gossypii (Ago) ago1945 ADR204W
Arabidopsis thaliana (Ath) ath9212 At2g23070.1
Arabidopsis thaliana (Ath) ath9213 At2g23080.1
Arabidopsis thaliana (Ath) ath16313 At3g50000.1
Arabidopsis thaliana (Ath) ath28922 At5g67380.1
Caenorhabditis elegans (Cel) cel137 B0205.7
(CE17321;
WBGene00002191)
Candida glabrata (Cgl) cgl1711 CAGL0G02035g
Candida glabrata (Cgl) cgl2747 CAGL0I05192g
Cryptococcus neoformans (Cne) cne1449 180.m00403
Dictyostelium discoideum (Ddi) ddi12128 DDB0185025
Debaryomyces hansenii (Dha) dha630 DEHA0A14080g
Debaryomyces hansenii (Dha) dha1762 DEHA0C07469g
Drosophila melanogaster (Dme) dme10791 CG17520-PA
(FBgn0000258)
Drosophila melanogaster (Dme) dme10793 CG17520-PB
(FBgn0000258)
Drosophila melanogaster (Dme) dme10792 CG17520-PC
(FBgn0000258)
Danio rerio (Dre) dre7486 ENSDARP00000003600
(LOC571171)
Danio rerio (Dre) dre7485 ENSDARP00000006001
(ck2a1)		 Q803N7
Danio rerio (Dre) dre29489 ENSDARP00000020745
Danio rerio (Dre) dre22067 ENSDARP00000027027
(ck2a2)		 Q7ZU33
Encephalitozoon cuniculi (Ecu) ecu1253 19173691
Takifugu rubripes (Fru) fru29594 SINFRUP00000138278
Gallus gallus (Gga) gga4341 ENSGALP00000001302
(CSNK2A2)		 P21869
Gallus gallus (Gga) gga12070 ENSGALP00000009985
(CSNK2A1)		 P21868
Homo sapiens (Hsa) hsa19634 ENSP00000217244
(CSNK2A1)		 P68400
Homo sapiens (Hsa) hsa12270 ENSP00000262506
(CSNK2A2)		 P19784
Homo sapiens (Hsa) hsa19635 ENSP00000339247
(CSNK2A1)		 P68400
Kluyveromyces lactis (Kla) kla3134 KLLA0E04136g
Kluyveromyces lactis (Kla) kla4820 KLLA0F16467g
Mus musculus (Mmu) mmu15738 ENSMUSP00000039756
Mus musculus (Mmu) mmu26488 ENSMUSP00000055919
(MGI:88547)		 O54833
Mus musculus (Mmu) mmu1279 ENSMUSP00000079835
Neurospora crassa (Ncr) ncr3028 NCU03124.2
Oryza sativa (Osa) osa50269 5904.m00136
Oryza sativa (Osa) osa51905 5988.m00131
Oryza sativa (Osa) osa66911 6940.m00150
Plasmodium falciparum (Pfa) pfa1044 PF11_0096
Rattus norvegicus (Rno) rno19977 ENSRNOP00000007558
(RGD:621663)		 P19139
Rattus norvegicus (Rno) rno14545 ENSRNOP00000016386
(RGD:1306882)		 B4F7A9
Saccharomyces cerevisiae (Sce) sce3049 YIL035C
(S000001297)
Saccharomyces cerevisiae (Sce) sce5795 YOR061W
(S000005587)
Schizosaccharomyces pombe (Spo) spo4936 SPAC23C11.11 P40231
Yarrowia lipolytica (Yli) yli1524 YALI0B18700g
Yarrowia lipolytica (Yli) yli3401 YALI0D16863g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
AthAt2g23080
GO:0005634 nucleus C
IDA
DmeFBgn0000258
SpoSPAC23C11.11
GO:0005654 nucleoplasm C
RCA
SceS000001297
GO:0005730 nucleolus C
IDA
SpoSPAC23C11.11
GO:0005737 cytoplasm C
IDA
DmeFBgn0000258
GO:0005829 cytosol C
IDA
DmeFBgn0000258
SpoSPAC23C11.11
GO:0005886 plasma membrane C
IDA
AthAt3g50000
GO:0005956 protein kinase CK2 complex C
IDA
DmeFBgn0000258
SceS000005587
S000001297
ISS
DmeFBgn0000258
PfaPF11_0096
NAS
DmeFBgn0000258
TAS
MmuMGI:88547
SpoSPAC23C11.11
GO:0031931 TORC1 complex C
IDA
SpoSPAC23C11.11
GO:0031932 TORC2 complex C
IDA
SpoSPAC23C11.11
GO:0034456 UTP-C complex C
IDA
SceS000001297
S000005587
GO:0004672 protein kinase activity F
NAS
DmeFBgn0000258
GO:0004674 protein serine/threonine kinase
activity		 F
IDA
DmeFBgn0000258
MmuMGI:88547
SceS000001297
S000005587
ISS
DmeFBgn0000258
SpoSPAC23C11.11
NAS
DmeFBgn0000258
GO:0005515 protein binding F
IPI
AthAt3g50000
GO:0005524 ATP binding F
ISS
SpoSPAC23C11.11
GO:0016301 kinase activity F
IDA
AthAt3g50000
At5g67380
ISS
AthAt3g50000
At5g67380
At2g23070
At2g23080
GO:0030234 enzyme regulator activity F
RCA
SceS000001297
GO:0000003 reproduction P
IMP
CelWBGene00002191
GO:0006356 regulation of transcription from RNA polymerase I
promoter		 P
IDA
SceS000001297
S000005587
GO:0006359 regulation of transcription from RNA polymerase
III promoter		 P
IDA
SceS000001297
S000005587
GO:0006468 protein amino acid phosphorylation P
IC
SpoSPAC23C11.11
IDA
DmeFBgn0000258
MmuMGI:88547
SceS000005587
S000001297
IMP
SceS000001297
ISS
DmeFBgn0000258
NAS
DmeFBgn0000258
GO:0006974 response to DNA damage stimulus P
IDA
SceS000001297
S000005587
GO:0007163 establishment or maintenance of cell
polarity		 P
IMP
SpoSPAC23C11.11
GO:0007411 axon guidance P
IMP
DmeFBgn0000258
GO:0007623 circadian rhythm P
IMP
DmeFBgn0000258
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00002191
GO:0016055 Wnt receptor signaling pathway P
IDA
DmeFBgn0000258
GO:0022416 bristle development P
IMP
DmeFBgn0000258
GO:0031929 TOR signaling cascade P
TAS
SpoSPAC23C11.11
GO:0034606 response to hermaphrodite contact P
IMP
CelWBGene00002191
GO:0034608 vulval location P
IMP
CelWBGene00002191
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00002191
GO:0040035 hermaphrodite genitalia development P
IMP
CelWBGene00002191
GO:0045475 locomotor rhythm P
IMP
DmeFBgn0000258
GO:0046331 lateral inhibition P
IMP
DmeFBgn0000258
GO:0048749 compound eye development P
IMP
DmeFBgn0000258
GO:0051726 regulation of cell cycle P
IDA
MmuMGI:88547

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPAC23C11.11
(P40231)		 YOR061W
(S000005587)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SpoSPAC23C11.11
GO:0005730 nucleolus C
IDA
SpoSPAC23C11.11
GO:0005829 cytosol C
IDA
SpoSPAC23C11.11
GO:0005956 protein kinase CK2 complex C
IDA
SceS000005587
TAS
SpoSPAC23C11.11
GO:0031931 TORC1 complex C
IDA
SpoSPAC23C11.11
GO:0031932 TORC2 complex C
IDA
SpoSPAC23C11.11
GO:0034456 UTP-C complex C
IDA
SceS000005587
GO:0004674 protein serine/threonine kinase
activity		 F
IDA
SceS000005587
ISS
SpoSPAC23C11.11
GO:0005524 ATP binding F
ISS
SpoSPAC23C11.11
GO:0006356 regulation of transcription from RNA polymerase I
promoter		 P
IDA
SceS000005587
GO:0006359 regulation of transcription from RNA polymerase
III promoter		 P
IDA
SceS000005587
GO:0006468 protein amino acid phosphorylation P
IC
SpoSPAC23C11.11
IDA
SceS000005587
GO:0006974 response to DNA damage stimulus P
IDA
SceS000005587
GO:0007163 establishment or maintenance of cell
polarity		 P
IMP
SpoSPAC23C11.11
GO:0031929 TOR signaling cascade P
TAS
SpoSPAC23C11.11

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s.khadayate@ucl.ac.uk