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Search term: YOR074C

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name CDC21
SGD link S000005600
Alternative ID YOR074C
Description Thymidylate synthase, required for de novo biosynthesis of pyrimidine deoxyribonucleotides; expression is induced at G1/S
Synonyms YOR074C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG0673 ACDHYPE

KOGs classification KOGs description
METABOLISM Thymidylate synthase

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At2g16370_2 GI:15227185
Arabidopsis thaliana (Ath) At2g21550_2 GI:15226577
Arabidopsis thaliana (Ath) At4g34570_2 GI:15236151
Caenorhabditis elegans (Cel) CE24124
(WBGene00022455)		 GI:17510913
Drosophila melanogaster (Dme) 7295876
(FBgn0024920)		 GI:17137556 O76511
Homo sapiens (Hsa) Hs4507751
(TYMS)		 GI:4507751 P04818
Saccharomyces cerevisiae (Sce) YOR074c
(S000005600)		 GI:6324648
Schizosaccharomyces pombe (Spo) SPAC15E1.04_2 GI:19115217 Q9UTI7
Encephalitozoon cuniculi (Ecu) ECU01g0180 GI:19075028
Encephalitozoon cuniculi (Ecu) ECU01g1430 GI:19075028
Encephalitozoon cuniculi (Ecu) ECU08g0090 GI:19173335 Q8SRG2
Arabidopsis thaliana (Ath) At2g16370_2 GI:15227185
Arabidopsis thaliana (Ath) At2g21550_2 GI:15226577
Arabidopsis thaliana (Ath) At4g34570_2 GI:15236151
Caenorhabditis elegans (Cel) CE24124
(WBGene00022455)		 GI:17510913
Drosophila melanogaster (Dme) 7295876
(FBgn0024920)		 GI:17137556 O76511
Homo sapiens (Hsa) Hs4507751
(TYMS)		 GI:4507751 P04818
Saccharomyces cerevisiae (Sce) YOR074c
(S000005600)		 GI:6324648
Schizosaccharomyces pombe (Spo) SPAC15E1.04_2 GI:19115217 Q9UTI7
Encephalitozoon cuniculi (Ecu) ECU01g0180 GI:19075028
Encephalitozoon cuniculi (Ecu) ECU01g1430 GI:19075028
Encephalitozoon cuniculi (Ecu) ECU08g0090 GI:19173335 Q8SRG2


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
AthAt2g16370
GO:0005634 nucleus C
IDA
SceS000005600
GO:0005829 cytosol C
IDA
SpoSPAC15E1.04
GO:0004146 dihydrofolate reductase activity F
ISS
AthAt2g16370
At4g34570
GO:0004799 thymidylate synthase activity F
IDA
SceS000005600
ISS
AthAt2g16370
At4g34570
DmeFBgn0024920
SpoSPAC15E1.04
NAS
DmeFBgn0024920
GO:0050660 FAD binding F
ISS
SpoSPAC15E1.04
GO:0000003 reproduction P
IMP
CelWBGene00022455
GO:0006139 nucleobase, nucleoside, nucleotide and nucleic
acid metabolic process		 P
TAS
HsaTYMS
GO:0006231 dTMP biosynthetic process P
ISS
SpoSPAC15E1.04
TAS
SceS000005600
GO:0006260 DNA replication P
NAS
HsaTYMS
GO:0006281 DNA repair P
NAS
HsaTYMS
GO:0009157 deoxyribonucleoside monophosphate biosynthetic
process		 P
TAS
HsaTYMS
GO:0009257 10-formyltetrahydrofolate biosynthetic
process		 P
ISS
AthAt4g34570
At2g16370
GO:0009263 deoxyribonucleotide biosynthetic
process		 P
NAS
DmeFBgn0024920
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00022455
GO:0010171 body morphogenesis P
IMP
CelWBGene00022455
GO:0032259 methylation P
ISS
SpoSPAC15E1.04
GO:0046683 response to organophosphorus P
IEP
HsaTYMS
GO:0048015 phosphoinositide-mediated signaling P
NAS
HsaTYMS

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
834

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) TYMS GI:4507751 P04818
Pan troglodytes (Ptr) TYMS GI:114672493
Canis familiaris (Cfa) LOC476100 GI:57100565
Canis familiaris (Cfa) LOC607417 GI:73961995
Mus musculus (Mmu) Tyms
(MGI:98878)		 GI:46358062 P07607
Rattus norvegicus (Rno) Tyms
(RGD:3921)		 GI:9507217 44649
Gallus gallus (Gga) TYMS GI:118086858
Drosophila melanogaster (Dme) Ts
(FBgn0024920)		 GI:17137556 O76511
Anopheles gambiae (Aga) AgaP_AGAP010457 GI:118781473
Caenorhabditis elegans (Cel) Y110A7A.4
(CE24124;
WBGene00022455)		 GI:71993377
Schizosaccharomyces pombe (Spo) SPAC15E1.04 GI:19115217 Q9UTI7
Saccharomyces cerevisiae (Sce) CDC21
(S000005600)		 GI:83578104
Kluyveromyces lactis (Kla) KLLA0A07843g GI:50302825
Eremothecium gossypii (Ego) AGOS_ADR219C GI:45188092
Magnaporthe grisea (Mgr) MGG_04458 GI:39944952
Neurospora crassa (Ncr) NCU10053.1 GI:32405614
Arabidopsis thaliana (Ath) THY-2 GI:30690081
Arabidopsis thaliana (Ath) THY-1 GI:15227185
Oryza sativa (Osa) Os11g0484400 GI:115485535
Oryza sativa (Osa) Os12g0446900 GI:115488458
Plasmodium falciparum (Pfa) PFD0805w GI:124505475


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
AthTHY-1
GO:0005625 soluble fraction C
ISO
MmuMGI:98878
GO:0005634 nucleus C
IDA
SceS000005600
GO:0005829 cytosol C
IDA
SpoSPAC15E1.04
GO:0000166 nucleotide binding F
ISO
MmuMGI:98878
GO:0004146 dihydrofolate reductase activity F
ISS
AthTHY-1
THY-2
GO:0004799 thymidylate synthase activity F
IDA
SceS000005600
ISO
MmuMGI:98878
ISS
AthTHY-1
THY-2
DmeFBgn0024920
SpoSPAC15E1.04
NAS
DmeFBgn0024920
GO:0005542 folic acid binding F
ISO
MmuMGI:98878
GO:0048037 cofactor binding F
ISO
MmuMGI:98878
GO:0050660 FAD binding F
ISS
SpoSPAC15E1.04
GO:0000003 reproduction P
IMP
CelWBGene00022455
GO:0006139 nucleobase, nucleoside, nucleotide and nucleic
acid metabolic process		 P
TAS
HsaTYMS
GO:0006231 dTMP biosynthetic process P
ISO
MmuMGI:98878
ISS
SpoSPAC15E1.04
TAS
SceS000005600
GO:0006260 DNA replication P
NAS
HsaTYMS
GO:0006281 DNA repair P
NAS
HsaTYMS
GO:0009157 deoxyribonucleoside monophosphate biosynthetic
process		 P
TAS
HsaTYMS
GO:0009257 10-formyltetrahydrofolate biosynthetic
process		 P
ISS
AthTHY-2
THY-1
GO:0009263 deoxyribonucleotide biosynthetic
process		 P
NAS
DmeFBgn0024920
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00022455
GO:0010171 body morphogenesis P
IMP
CelWBGene00022455
GO:0032259 methylation P
ISS
SpoSPAC15E1.04
GO:0046078 dUMP metabolic process P
ISO
MmuMGI:98878
GO:0046683 response to organophosphorus P
IEP
HsaTYMS
GO:0048015 phosphoinositide-mediated signaling P
NAS
HsaTYMS

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_1089

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga7293 ENSANGP00000013700
Ashbya gossypii (Ago) ago1960 ADR219C
Arabidopsis thaliana (Ath) ath8472 At2g16370.1
Arabidopsis thaliana (Ath) ath21602 At4g34570.1
Caenorhabditis elegans (Cel) cel17631 Y110A7A.4
(CE24124;
WBGene00022455)
Candida glabrata (Cgl) cgl3758 CAGL0K05467g
Cryptococcus neoformans (Cne) cne3883 185.m02470
Debaryomyces hansenii (Dha) dha1738 DEHA0C06853g
Drosophila melanogaster (Dme) dme503 CG3181-PA
(FBgn0024920)
Danio rerio (Dre) dre8822 ENSDARP00000029093
Escherichia coli (Eco) eco2731 16130731
Encephalitozoon cuniculi (Ecu) ecu1665 19075028
Encephalitozoon cuniculi (Ecu) ecu1793 19075156
Encephalitozoon cuniculi (Ecu) ecu166 19173335
Takifugu rubripes (Fru) fru19816 SINFRUP00000142407
Gallus gallus (Gga) gga10983 ENSGALP00000023982
(TYMS)
Gallus gallus (Gga) gga10984 ENSGALP00000023983
Gallus gallus (Gga) gga10985 ENSGALP00000023984
Gallus gallus (Gga) gga10986 ENSGALP00000023985
Homo sapiens (Hsa) hsa14653 ENSP00000314727
(TYMS)		 Q8WYK3
Homo sapiens (Hsa) hsa14654 ENSP00000314902
(TYMS)		 Q8WYK4
Homo sapiens (Hsa) hsa14652 ENSP00000315644
(TYMS)		 P04818
Kluyveromyces lactis (Kla) kla346 KLLA0A07843g
Mus musculus (Mmu) mmu19838 ENSMUSP00000026846
(MGI:98878)		 P07607
Neurospora crassa (Ncr) ncr9787 NCU10053.2
Oryza sativa (Osa) osa68731 7026.m00141
Oryza sativa (Osa) osa74171 7168.m00149
Plasmodium falciparum (Pfa) pfa3324 PFD0830w
Saccharomyces cerevisiae (Sce) sce5811 YOR074C
(S000005600)
Schizosaccharomyces pombe (Spo) spo2837 SPAC15E1.04 Q9UTI7
Yarrowia lipolytica (Yli) yli2168 YALI0C10901g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
AthAt2g16370
GO:0005625 soluble fraction C
ISO
MmuMGI:98878
GO:0005634 nucleus C
IDA
SceS000005600
GO:0005829 cytosol C
IDA
SpoSPAC15E1.04
GO:0000166 nucleotide binding F
ISO
MmuMGI:98878
GO:0004146 dihydrofolate reductase activity F
ISS
AthAt2g16370
At4g34570
GO:0004799 thymidylate synthase activity F
IDA
SceS000005600
ISO
MmuMGI:98878
ISS
AthAt2g16370
At4g34570
DmeFBgn0024920
SpoSPAC15E1.04
NAS
DmeFBgn0024920
GO:0005542 folic acid binding F
ISO
MmuMGI:98878
GO:0048037 cofactor binding F
ISO
MmuMGI:98878
GO:0050660 FAD binding F
ISS
SpoSPAC15E1.04
GO:0000003 reproduction P
IMP
CelWBGene00022455
GO:0006231 dTMP biosynthetic process P
ISO
MmuMGI:98878
ISS
SpoSPAC15E1.04
TAS
SceS000005600
GO:0009257 10-formyltetrahydrofolate biosynthetic
process		 P
ISS
AthAt4g34570
At2g16370
GO:0009263 deoxyribonucleotide biosynthetic
process		 P
NAS
DmeFBgn0024920
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00022455
GO:0010171 body morphogenesis P
IMP
CelWBGene00022455
GO:0032259 methylation P
ISS
SpoSPAC15E1.04
GO:0046078 dUMP metabolic process P
ISO
MmuMGI:98878

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GO info in one table:

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