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Search term: YOR076C

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name SKI7
SGD link S000005602
Alternative ID YOR076C
Description Coupling protein that mediates interactions between the Ski complex and the cytoplasmic exosome during 3'-5' RNA degradation; eRF3-like domain targets nonstop mRNA for degradation; null mutants have superkiller phenotype
Synonyms YOR076C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG0458 ACDHYP-

KOGs classification KOGs description
INFORMATION STORAGE AND PROCESSING Elongation factor 1 alpha

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At5g10630_2 GI:15238216
Caenorhabditis elegans (Cel) CE25933 GI:17508141
Drosophila melanogaster (Dme) 7292173_2 GI:7292173
Homo sapiens (Hsa) Hs5729864_2
(HBS1L)		 GI:5729864 Q9Y450
Saccharomyces cerevisiae (Sce) YKR084c
(S000001792)		 GI:6322937 P32769
Saccharomyces cerevisiae (Sce) YOR076c
(S000005602)		 GI:6324650 Q08491
Schizosaccharomyces pombe (Spo) SPAP8A3.05 GI:19115856 Q9UT10
Schizosaccharomyces pombe (Spo) SPBC2G5.08 GI:19112861
Arabidopsis thaliana (Ath) At5g10630_2 GI:15238216
Caenorhabditis elegans (Cel) CE25933 GI:17508141
Drosophila melanogaster (Dme) 7292173_2 GI:7292173
Homo sapiens (Hsa) Hs5729864_2
(HBS1L)		 GI:5729864 Q9Y450
Saccharomyces cerevisiae (Sce) YKR084c
(S000001792)		 GI:6322937 P32769
Saccharomyces cerevisiae (Sce) YOR076c
(S000005602)		 GI:6324650 Q08491
Schizosaccharomyces pombe (Spo) SPAP8A3.05 GI:19115856 Q9UT10
Schizosaccharomyces pombe (Spo) SPBC2G5.08 GI:19112861
Arabidopsis thaliana (Ath) At5g10630_2 GI:15238216
Caenorhabditis elegans (Cel) CE25933 GI:17508141
Drosophila melanogaster (Dme) 7292173_2 GI:7292173
Homo sapiens (Hsa) Hs5729864_2
(HBS1L)		 GI:5729864 Q9Y450
Saccharomyces cerevisiae (Sce) YKR084c
(S000001792)		 GI:6322937 P32769
Saccharomyces cerevisiae (Sce) YOR076c
(S000005602)		 GI:6324650 Q08491
Schizosaccharomyces pombe (Spo) SPAP8A3.05 GI:19115856 Q9UT10
Schizosaccharomyces pombe (Spo) SPBC2G5.08 GI:19112861


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000177 cytoplasmic exosome (RNase complex) C
IDA
SceS000005602
GO:0000178 exosome (RNase complex) C
ISS
SpoSPAP8A3.05
GO:0005634 nucleus C
IDA
SpoSPAP8A3.05
GO:0005737 cytoplasm C
IDA
SceS000005602
S000001792
GO:0005829 cytosol C
IDA
SpoSPAP8A3.05
GO:0055087 Ski complex C
IDA
SceS000005602
GO:0003674 molecular_function F
ND
SceS000001792
GO:0003746 translation elongation factor activity F
ISS
AthAt5g10630
GO:0005525 GTP binding F
ISS
SpoSPAP8A3.05
GO:0030674 protein binding, bridging F
IMP
SceS000005602
GO:0006401 RNA catabolic process P
RCA
SceS000005602
GO:0006402 mRNA catabolic process P
ISS
SpoSPAP8A3.05
GO:0006412 translation P
IMP
SceS000001792
IPI
SceS000001792
GO:0006415 translational termination P
RCA
SceS000001792
GO:0007165 signal transduction P
TAS
HsaHBS1L
GO:0008150 biological_process P
ND
AthAt5g10630
GO:0031123 RNA 3'-end processing P
RCA
SceS000005602
GO:0034427 nuclear-transcribed mRNA catabolic process,
exonucleolytic, 3'-5'		 P
IGI
SceS000005602
IMP
SceS000005602
GO:0070478 nuclear-transcribed mRNA catabolic process, 3'-5'
exonucleolytic nonsense-mediated
decay		 P
IGI
SceS000005602
IMP
SceS000005602
GO:0070481 nuclear-transcribed mRNA catabolic process,
non-stop decay		 P
IMP
SceS000005602
GO:0070651 nonfunctional rRNA decay P
IMP
SceS000005602
S000001792
GO:0070966 nuclear-transcribed mRNA catabolic process, no-go
decay		 P
IGI
SceS000001792

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_60005

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Candida glabrata (Cgl) cgl3760 CAGL0K05511g
Saccharomyces cerevisiae (Sce) sce5813 YOR076C
(S000005602)


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000177 cytoplasmic exosome (RNase complex) C
IDA
SceS000005602
GO:0005737 cytoplasm C
IDA
SceS000005602
GO:0055087 Ski complex C
IDA
SceS000005602
GO:0030674 protein binding, bridging F
IMP
SceS000005602
GO:0006401 RNA catabolic process P
RCA
SceS000005602
GO:0031123 RNA 3'-end processing P
RCA
SceS000005602
GO:0034427 nuclear-transcribed mRNA catabolic process,
exonucleolytic, 3'-5'		 P
IGI
SceS000005602
IMP
SceS000005602
GO:0070478 nuclear-transcribed mRNA catabolic process, 3'-5'
exonucleolytic nonsense-mediated
decay		 P
IGI
SceS000005602
IMP
SceS000005602
GO:0070481 nuclear-transcribed mRNA catabolic process,
non-stop decay		 P
IMP
SceS000005602
GO:0070651 nonfunctional rRNA decay P
IMP
SceS000005602

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPAP8A3.05
(Q9UT10)		 YOR076C
(S000005602)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000177 cytoplasmic exosome (RNase complex) C
IDA
SceS000005602
GO:0000178 exosome (RNase complex) C
ISS
SpoSPAP8A3.05
GO:0005634 nucleus C
IDA
SpoSPAP8A3.05
GO:0005737 cytoplasm C
IDA
SceS000005602
GO:0005829 cytosol C
IDA
SpoSPAP8A3.05
GO:0055087 Ski complex C
IDA
SceS000005602
GO:0005525 GTP binding F
ISS
SpoSPAP8A3.05
GO:0030674 protein binding, bridging F
IMP
SceS000005602
GO:0006401 RNA catabolic process P
RCA
SceS000005602
GO:0006402 mRNA catabolic process P
ISS
SpoSPAP8A3.05
GO:0031123 RNA 3'-end processing P
RCA
SceS000005602
GO:0034427 nuclear-transcribed mRNA catabolic process,
exonucleolytic, 3'-5'		 P
IGI
SceS000005602
IMP
SceS000005602
GO:0070478 nuclear-transcribed mRNA catabolic process, 3'-5'
exonucleolytic nonsense-mediated
decay		 P
IGI
SceS000005602
IMP
SceS000005602
GO:0070481 nuclear-transcribed mRNA catabolic process,
non-stop decay		 P
IMP
SceS000005602
GO:0070651 nonfunctional rRNA decay P
IMP
SceS000005602

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