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Search term: YOR086C

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name TCB1
SGD link S000005612
Alternative ID YOR086C
Description Lipid-binding protein containing three calcium and lipid binding domains; non-tagged protein localizes to mitochondria and GFP-fusion protein localizes to the cell periphery; C-termini of Tcb1p, Tcb2p and Tcb3p interact
Synonyms YOR086C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG1012 ACDHYPE

KOGs classification KOGs description
POORLY CHARACTERIZED Ca2+-dependent lipid-binding protein CLB1/vesicle protein vp115/Granuphilin A, contains C2 domain

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At1g05500 GI:15220525
Arabidopsis thaliana (Ath) At1g20080 GI:15223764
Arabidopsis thaliana (Ath) At1g50260 GI:15222915
Arabidopsis thaliana (Ath) At1g53590 GI:12324036
Arabidopsis thaliana (Ath) At2g20990 GI:15226434
Arabidopsis thaliana (Ath) At2g21010 GI:15226445
Arabidopsis thaliana (Ath) At2g21040_1 GI:15226449
Arabidopsis thaliana (Ath) At3g14590 GI:15231887
Arabidopsis thaliana (Ath) At3g18370 GI:15229634
Arabidopsis thaliana (Ath) At3g19830 GI:15230957
Arabidopsis thaliana (Ath) At3g60950_1 GI:15232998
Arabidopsis thaliana (Ath) At3g61030_1 GI:18411789
Arabidopsis thaliana (Ath) At3g61050 GI:15233028
Arabidopsis thaliana (Ath) At5g04220 GI:9955577
Arabidopsis thaliana (Ath) At5g11100 GI:15238948
Caenorhabditis elegans (Cel) CE18256 GI:17555020
Drosophila melanogaster (Dme) 7301181 GI:7301181 Q9VC62
Homo sapiens (Hsa) Hs11128045_3 GI:11128045
Homo sapiens (Hsa) Hs14149680
(FAM62A)		 GI:14149680 Q9BSJ8
Homo sapiens (Hsa) Hs14730527_1 GI:14730527
Homo sapiens (Hsa) Hs22043833 GI:22043833
Homo sapiens (Hsa) Hs22045984 GI:22045984
Saccharomyces cerevisiae (Sce) YML072c
(S000004537)		 GI:6323568 Q03640
Saccharomyces cerevisiae (Sce) YNL087w
(S000005031)		 GI:6324242 P48231
Saccharomyces cerevisiae (Sce) YOR086c
(S000005612)		 GI:6324660 Q12466
Schizosaccharomyces pombe (Spo) SPAPYUK71.03c GI:19114886 Q9UT00
Schizosaccharomyces pombe (Spo) SPCC962.01 GI:19075365 O14065
Schizosaccharomyces pombe (Spo) SPCP31B10.06 GI:19075362 Q9USG8
Encephalitozoon cuniculi (Ecu) ECU01g1250 GI:19075138
Arabidopsis thaliana (Ath) At1g05500 GI:15220525
Arabidopsis thaliana (Ath) At1g20080 GI:15223764
Arabidopsis thaliana (Ath) At1g50260 GI:15222915
Arabidopsis thaliana (Ath) At1g53590 GI:12324036
Arabidopsis thaliana (Ath) At2g20990 GI:15226434
Arabidopsis thaliana (Ath) At2g21010 GI:15226445
Arabidopsis thaliana (Ath) At2g21040_1 GI:15226449
Arabidopsis thaliana (Ath) At3g14590 GI:15231887
Arabidopsis thaliana (Ath) At3g18370 GI:15229634
Arabidopsis thaliana (Ath) At3g19830 GI:15230957
Arabidopsis thaliana (Ath) At3g60950_1 GI:15232998
Arabidopsis thaliana (Ath) At3g61030_1 GI:18411789
Arabidopsis thaliana (Ath) At3g61050 GI:15233028
Arabidopsis thaliana (Ath) At5g04220 GI:9955577
Arabidopsis thaliana (Ath) At5g11100 GI:15238948
Caenorhabditis elegans (Cel) CE18256 GI:17555020
Drosophila melanogaster (Dme) 7301181 GI:7301181 Q9VC62
Homo sapiens (Hsa) Hs11128045_3 GI:11128045
Homo sapiens (Hsa) Hs14149680
(FAM62A)		 GI:14149680 Q9BSJ8
Homo sapiens (Hsa) Hs14730527_1 GI:14730527
Homo sapiens (Hsa) Hs22043833 GI:22043833
Homo sapiens (Hsa) Hs22045984 GI:22045984
Saccharomyces cerevisiae (Sce) YML072c
(S000004537)		 GI:6323568 Q03640
Saccharomyces cerevisiae (Sce) YNL087w
(S000005031)		 GI:6324242 P48231
Saccharomyces cerevisiae (Sce) YOR086c
(S000005612)		 GI:6324660 Q12466
Schizosaccharomyces pombe (Spo) SPAPYUK71.03c GI:19114886 Q9UT00
Schizosaccharomyces pombe (Spo) SPCC962.01 GI:19075365 O14065
Schizosaccharomyces pombe (Spo) SPCP31B10.06 GI:19075362 Q9USG8
Encephalitozoon cuniculi (Ecu) ECU01g1250 GI:19075138


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0001950 plasma membrane enriched fraction C
IDA
SceS000005612
GO:0005575 cellular_component C
ND
AthAt2g21010
At3g61030
At2g21040
GO:0005634 nucleus C
IDA
SpoSPCP31B10.06
GO:0005739 mitochondrion C
IDA
SceS000004537
S000005612
GO:0005768 endosome C
IDA
AthAt2g20990
GO:0005773 vacuole C
IDA
AthAt2g20990
At1g53590
GO:0005783 endoplasmic reticulum C
IDA
SpoSPCP31B10.06
SPAPYUK71.03c
GO:0005794 Golgi apparatus C
IDA
SpoSPAPYUK71.03c
GO:0005816 spindle pole body C
IDA
SpoSPCP31B10.06
GO:0005829 cytosol C
IDA
SpoSPCP31B10.06
GO:0005886 plasma membrane C
IDA
AthAt1g53590
At2g20990
At3g61050
At3g60950
At1g05500
GO:0005933 cellular bud C
IDA
SceS000004537
S000005031
GO:0009507 chloroplast C
IDA
AthAt3g14590
GO:0012505 endomembrane system C
IDA
AthAt1g05500
GO:0016020 membrane C
IDA
AthAt2g20990
NAS
SpoSPCC962.01
SPCP31B10.06
GO:0030659 cytoplasmic vesicle membrane C
NAS
SpoSPAPYUK71.03c
GO:0031410 cytoplasmic vesicle C
IDA
SpoSPAPYUK71.03c
GO:0051286 cell tip C
IDA
SpoSPAPYUK71.03c
GO:0003674 molecular_function F
ND
AthAt2g21040
At5g04220
At1g20080
At5g11100
At3g60950
At2g20990
At1g50260
At2g21010
At1g05500
At3g61030
At3g19830
At3g18370
SceS000005031
GO:0005509 calcium ion binding F
NAS
SpoSPAPYUK71.03c
GO:0005543 phospholipid binding F
ISS
SpoSPCC962.01
SPCP31B10.06
SPAPYUK71.03c
GO:0008289 lipid binding F
IDA
SceS000004537
S000005612
ISS
AthAt3g61050
SpoSPAPYUK71.03c
SPCC962.01
SPCP31B10.06
RCA
SceS000005031
GO:0001778 plasma membrane repair P
IMP
AthAt2g20990
GO:0006612 protein targeting to membrane P
ISS
AthAt2g20990
GO:0006897 endocytosis P
IMP
AthAt2g20990
GO:0006906 vesicle fusion P
NAS
SpoSPAPYUK71.03c
GO:0008150 biological_process P
ND
AthAt3g18370
At1g05500
At1g20080
At3g61050
At5g04220
At3g60950
At3g61030
At1g50260
At2g21040
At5g11100
At3g19830
At2g21010
SceS000005612
S000004537
S000005031
GO:0009409 response to cold P
IMP
AthAt2g20990
GO:0009615 response to virus P
IPI
AthAt2g20990
GO:0032456 endocytic recycling P
IMP
AthAt2g20990
GO:0033554 cellular response to stress P
IEP
SpoSPCC962.01
SPCP31B10.06
GO:0046740 spread of virus in host, cell to
cell		 P
IMP
AthAt2g20990

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
40260

Species Gene ID NCBI link UniProt link
Saccharomyces cerevisiae (Sce) TCB1
(S000005612)		 GI:6324660 Q12466
Kluyveromyces lactis (Kla) KLLA0C13860g GI:50305717
Eremothecium gossypii (Ego) AGOS_AER411W GI:45191012


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0001950 plasma membrane enriched fraction C
IDA
SceS000005612
GO:0005739 mitochondrion C
IDA
SceS000005612
GO:0008289 lipid binding F
IDA
SceS000005612
GO:0008150 biological_process P
ND
SceS000005612

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_3534

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Ashbya gossypii (Ago) ago2652 AER148W
Ashbya gossypii (Ago) ago2911 AER411W
Arabidopsis thaliana (Ath) ath506 At1g05500.1
Arabidopsis thaliana (Ath) ath2154 At1g20080.1
Arabidopsis thaliana (Ath) ath8987 At2g20990.1
Candida glabrata (Cgl) cgl3366 CAGL0J08591g
Candida glabrata (Cgl) cgl4573 CAGL0L11440g
Cryptococcus neoformans (Cne) cne5426 179.m00279
Debaryomyces hansenii (Dha) dha1946 DEHA0C11660g
Debaryomyces hansenii (Dha) dha2756 DEHA0D10373g
Danio rerio (Dre) dre19837 ENSDARP00000012351
Encephalitozoon cuniculi (Ecu) ecu1775 19075138
Takifugu rubripes (Fru) fru3885 SINFRUP00000140448
Kluyveromyces lactis (Kla) kla741 KLLA0B04708g
Kluyveromyces lactis (Kla) kla1818 KLLA0C13860g
Mus musculus (Mmu) mmu24176 ENSMUSP00000072028
Neurospora crassa (Ncr) ncr3161 NCU03263.2
Oryza sativa (Osa) osa28884 4258.m00114
Oryza sativa (Osa) osa31245 4378.m00140
Oryza sativa (Osa) osa62900 6609.m00203
Oryza sativa (Osa) osa66059 6776.m00142
Oryza sativa (Osa) osa66090 6776.m00160
Saccharomyces cerevisiae (Sce) sce4676 YML072C
(S000004537)
Saccharomyces cerevisiae (Sce) sce5200 YNL087W
(S000005031)
Saccharomyces cerevisiae (Sce) sce5823 YOR086C
(S000005612)
Schizosaccharomyces pombe (Spo) spo3699 SPAPYUK71.03c Q9UT00
Schizosaccharomyces pombe (Spo) spo4767 SPCC962.01 O14065
Yarrowia lipolytica (Yli) yli5151 YALI0E31196g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0001950 plasma membrane enriched fraction C
IDA
SceS000005612
GO:0005739 mitochondrion C
IDA
SceS000004537
S000005612
GO:0005768 endosome C
IDA
AthAt2g20990
GO:0005773 vacuole C
IDA
AthAt2g20990
GO:0005783 endoplasmic reticulum C
IDA
SpoSPAPYUK71.03c
GO:0005794 Golgi apparatus C
IDA
SpoSPAPYUK71.03c
GO:0005886 plasma membrane C
IDA
AthAt2g20990
At1g05500
GO:0005933 cellular bud C
IDA
SceS000004537
S000005031
GO:0012505 endomembrane system C
IDA
AthAt1g05500
GO:0016020 membrane C
IDA
AthAt2g20990
NAS
SpoSPCC962.01
GO:0030659 cytoplasmic vesicle membrane C
NAS
SpoSPAPYUK71.03c
GO:0031410 cytoplasmic vesicle C
IDA
SpoSPAPYUK71.03c
GO:0051286 cell tip C
IDA
SpoSPAPYUK71.03c
GO:0003674 molecular_function F
ND
AthAt1g20080
At2g20990
At1g05500
SceS000005031
GO:0005509 calcium ion binding F
NAS
SpoSPAPYUK71.03c
GO:0005543 phospholipid binding F
ISS
SpoSPCC962.01
SPAPYUK71.03c
GO:0008289 lipid binding F
IDA
SceS000004537
S000005612
ISS
SpoSPAPYUK71.03c
SPCC962.01
RCA
SceS000005031
GO:0001778 plasma membrane repair P
IMP
AthAt2g20990
GO:0006612 protein targeting to membrane P
ISS
AthAt2g20990
GO:0006897 endocytosis P
IMP
AthAt2g20990
GO:0006906 vesicle fusion P
NAS
SpoSPAPYUK71.03c
GO:0008150 biological_process P
ND
AthAt1g05500
At1g20080
SceS000005612
S000004537
S000005031
GO:0009409 response to cold P
IMP
AthAt2g20990
GO:0009615 response to virus P
IPI
AthAt2g20990
GO:0032456 endocytic recycling P
IMP
AthAt2g20990
GO:0033554 cellular response to stress P
IEP
SpoSPCC962.01
GO:0046740 spread of virus in host, cell to
cell		 P
IMP
AthAt2g20990

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPCP31B10.06
(Q9USG8)		 YOR086C
(S000005612)
SPCC962.01
(O14065)		 YOR086C
(S000005612)
SPAPYUK71.03c
(Q9UT00)		 YOR086C
(S000005612)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0001950 plasma membrane enriched fraction C
IDA
SceS000005612
GO:0005634 nucleus C
IDA
SpoSPCP31B10.06
GO:0005739 mitochondrion C
IDA
SceS000005612
GO:0005783 endoplasmic reticulum C
IDA
SpoSPCP31B10.06
SPAPYUK71.03c
GO:0005794 Golgi apparatus C
IDA
SpoSPAPYUK71.03c
GO:0005816 spindle pole body C
IDA
SpoSPCP31B10.06
GO:0005829 cytosol C
IDA
SpoSPCP31B10.06
GO:0016020 membrane C
NAS
SpoSPCC962.01
SPCP31B10.06
GO:0030659 cytoplasmic vesicle membrane C
NAS
SpoSPAPYUK71.03c
GO:0031410 cytoplasmic vesicle C
IDA
SpoSPAPYUK71.03c
GO:0051286 cell tip C
IDA
SpoSPAPYUK71.03c
GO:0005509 calcium ion binding F
NAS
SpoSPAPYUK71.03c
GO:0005543 phospholipid binding F
ISS
SpoSPCC962.01
SPCP31B10.06
SPAPYUK71.03c
GO:0008289 lipid binding F
IDA
SceS000005612
ISS
SpoSPAPYUK71.03c
SPCC962.01
SPCP31B10.06
GO:0006906 vesicle fusion P
NAS
SpoSPAPYUK71.03c
GO:0008150 biological_process P
ND
SceS000005612
GO:0033554 cellular response to stress P
IEP
SpoSPCC962.01
SPCP31B10.06

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