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Search term: YOR109W

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name INP53
SGD link S000005635
Alternative ID YOR109W
Description Polyphosphatidylinositol phosphatase, dephosphorylates multiple phosphatidylinositols; involved in trans Golgi network-to-early endosome pathway; hyperosmotic stress causes translocation to actin patches; contains Sac1 and 5-ptase domains
Synonyms YOR109W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG0566 -CDHYPE

KOGs classification KOGs description
CELLULAR PROCESSES AND SIGNALING Inositol-1,4,5-triphosphate 5-phosphatase (synaptojanin), INP51/INP52/INP53 family

Species KOG link NCBI link UniProt link
Caenorhabditis elegans (Cel) CE28239
(WBGene00006763)		 GI:17541150
Caenorhabditis elegans (Cel) CE29050 GI:17541152
Drosophila melanogaster (Dme) 7291368
(FBgn0034691)		 GI:18497296
Homo sapiens (Hsa) Hs4507335 GI:4507335
Homo sapiens (Hsa) Hs14747866 GI:14747866
Saccharomyces cerevisiae (Sce) YIL002c
(S000001264)		 GI:6322189 P40559
Saccharomyces cerevisiae (Sce) YNL106c
(S000005050)		 GI:6324224 P50942
Saccharomyces cerevisiae (Sce) YOR109w
(S000005635)		 GI:6324683 Q12271
Schizosaccharomyces pombe (Spo) SPBC2G2.02 GI:19113223 O43001
Schizosaccharomyces pombe (Spo) SPBC577.13 GI:19112103 Q9USQ6
Encephalitozoon cuniculi (Ecu) ECU08g1420 GI:19173467 Q8SUM4
Caenorhabditis elegans (Cel) CE28239
(WBGene00006763)		 GI:17541150
Caenorhabditis elegans (Cel) CE29050 GI:17541152
Drosophila melanogaster (Dme) 7291368
(FBgn0034691)		 GI:18497296
Homo sapiens (Hsa) Hs4507335 GI:4507335
Homo sapiens (Hsa) Hs14747866 GI:14747866
Saccharomyces cerevisiae (Sce) YIL002c
(S000001264)		 GI:6322189 P40559
Saccharomyces cerevisiae (Sce) YNL106c
(S000005050)		 GI:6324224 P50942
Saccharomyces cerevisiae (Sce) YOR109w
(S000005635)		 GI:6324683 Q12271
Schizosaccharomyces pombe (Spo) SPBC2G2.02 GI:19113223 O43001
Schizosaccharomyces pombe (Spo) SPBC577.13 GI:19112103 Q9USQ6
Encephalitozoon cuniculi (Ecu) ECU08g1420 GI:19173467 Q8SUM4


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005624 membrane fraction C
IDA
SceS000001264
S000005635
GO:0005737 cytoplasm C
IDA
SceS000001264
S000005050
S000005635
SpoSPBC577.13
GO:0005829 cytosol C
IDA
SpoSPBC2G2.02
GO:0008021 synaptic vesicle C
ISS
CelWBGene00006763
GO:0012506 vesicle membrane C
IDA
DmeFBgn0034691
GO:0030479 actin cortical patch C
IDA
SceS000005050
S000005635
IPI
SceS000005050
GO:0032153 cell division site C
IDA
SpoSPBC2G2.02
GO:0042598 vesicular fraction C
IDA
SceS000005050
S000005635
GO:0043195 terminal button C
IDA
DmeFBgn0034691
GO:0043332 mating projection tip C
IDA
SceS000005050
GO:0045202 synapse C
IDA
CelWBGene00006763
GO:0051286 cell tip C
IDA
SpoSPBC2G2.02
GO:0004437 inositol or phosphatidylinositol phosphatase
activity		 F
ISS
CelWBGene00006763
GO:0004438 phosphatidylinositol-3-phosphatase
activity		 F
IDA
SceS000005050
S000005635
RCA
SceS000001264
GO:0004439 phosphatidylinositol-4,5-bisphosphate
5-phosphatase activity		 F
IDA
SceS000001264
S000005050
S000005635
IMP
SceS000001264
S000005050
S000005635
ISS
SpoSPBC2G2.02
GO:0004445 inositol-polyphosphate 5-phosphatase
activity		 F
IDA
DmeFBgn0034691
SpoSPBC2G2.02
ISS
SpoSPBC577.13
GO:0042577 lipid phosphatase activity F
RCA
SceS000001264
GO:0043812 phosphatidylinositol-4-phosphate phosphatase
activity		 F
IDA
SceS000005635
S000005050
RCA
SceS000001264
GO:0043813 phosphatidylinositol-3,5-bisphosphate
5-phosphatase activity		 F
IDA
SceS000005050
S000005635
RCA
SceS000001264
GO:0046030 inositol trisphosphate phosphatase
activity		 F
NAS
DmeFBgn0034691
GO:0001956 positive regulation of neurotransmitter
secretion		 P
IMP
CelWBGene00006763
GO:0006414 translational elongation P
RCA
SceS000005635
GO:0006897 endocytosis P
ISS
SpoSPBC577.13
SPBC2G2.02
GO:0006936 muscle contraction P
IMP
CelWBGene00006763
GO:0006970 response to osmotic stress P
RCA
SceS000005050
GO:0007010 cytoskeleton organization P
IMP
CelWBGene00006763
GO:0007032 endosome organization P
IMP
CelWBGene00006763
GO:0007269 neurotransmitter secretion P
NAS
DmeFBgn0034691
GO:0015812 gamma-aminobutyric acid transport P
IMP
CelWBGene00006763
GO:0015870 acetylcholine transport P
IMP
CelWBGene00006763
GO:0016050 vesicle organization P
IMP
CelWBGene00006763
GO:0016185 synaptic vesicle budding from presynaptic
membrane		 P
IMP
CelWBGene00006763
GO:0016191 synaptic vesicle uncoating P
IMP
CelWBGene00006763
GO:0016311 dephosphorylation P
NAS
DmeFBgn0034691
GO:0033554 cellular response to stress P
IEP
SpoSPBC577.13
GO:0040011 locomotion P
IMP
CelWBGene00006763
GO:0040018 positive regulation of multicellular organism
growth		 P
IMP
CelWBGene00006763
GO:0043050 pharyngeal pumping P
IMP
CelWBGene00006763
GO:0043058 regulation of backward locomotion P
IMP
CelWBGene00006763
GO:0043059 regulation of forward locomotion P
IMP
CelWBGene00006763
GO:0045933 positive regulation of muscle contraction P
IMP
CelWBGene00006763
GO:0046488 phosphatidylinositol metabolic
process		 P
ISS
SpoSPBC2G2.02
SPBC577.13
GO:0046856 phosphoinositide dephosphorylation P
IDA
SceS000005050
S000001264
S000005635
IMP
SceS000005050
S000001264
S000005635
ISS
SpoSPBC2G2.02
SPBC577.13
GO:0048017 inositol lipid-mediated signaling P
IC
SpoSPBC2G2.02
SPBC577.13
GO:0048212 Golgi vesicle uncoating P
IMP
CelWBGene00006763
GO:0048488 synaptic vesicle endocytosis P
IMP
CelWBGene00006763
DmeFBgn0034691
TAS
DmeFBgn0034691
GO:0048489 synaptic vesicle transport P
IMP
CelWBGene00006763
GO:0048790 maintenance of presynaptic active zone
structure		 P
IMP
DmeFBgn0034691
GO:0050803 regulation of synapse structure and
activity		 P
IMP
DmeFBgn0034691
GO:0051049 regulation of transport P
RCA
SceS000005050
GO:0051248 negative regulation of protein metabolic
process		 P
RCA
SceS000005050

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
48252

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) SYNJ1 GI:44921606
Pan troglodytes (Ptr) SYNJ1 GI:114684345
Canis familiaris (Cfa) SYNJ1 GI:74001111
Mus musculus (Mmu) Synj1
(MGI:1354961)		 GI:149268189 Q8CHC4
Rattus norvegicus (Rno) Synj1
(RGD:69434)		 GI:109492922
Gallus gallus (Gga) SYNJ1 GI:118083842
Drosophila melanogaster (Dme) synj
(FBgn0034691)		 GI:18497296
Anopheles gambiae (Aga) AgaP_AGAP012175 GI:158300438
Caenorhabditis elegans (Cel) unc-26
(CE28239;
WBGene00006763)		 GI:71990655
Schizosaccharomyces pombe (Spo) SPBC2G2.02 GI:19113223 O43001
Saccharomyces cerevisiae (Sce) INP53
(S000005635)		 GI:6324683 Q12271
Saccharomyces cerevisiae (Sce) INP52
(S000005050)		 GI:6324224 P50942
Kluyveromyces lactis (Kla) KLLA0F23551g GI:50312195
Eremothecium gossypii (Ego) AGOS_AFL228W GI:45198293
Magnaporthe grisea (Mgr) MGG_04549 GI:39945134
Neurospora crassa (Ncr) NCU03298.1 GI:32420581