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Search term: YOR130C

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name ORT1
SGD link S000005656
Alternative ID YOR130C
Description Ornithine transporter of the mitochondrial inner membrane, exports ornithine from mitochondria as part of arginine biosynthesis; human ortholog is associated with hyperammonaemia-hyperornithinaemia-homocitrullinuria (HHH) syndrome
Synonyms YOR130C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG0758 ACDHYP-

KOGs classification KOGs description
METABOLISM Mitochondrial carnitine-acylcarnitine carrier protein

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At2g33820 GI:15226171
Arabidopsis thaliana (Ath) At5g46800 GI:9758516
Caenorhabditis elegans (Cel) CE06272 GI:17562944
Caenorhabditis elegans (Cel) CE28408
(WBGene00000996)		 GI:17539560 Q27257
Drosophila melanogaster (Dme) 7295910
(FBgn0019830)		 GI:17137310
Drosophila melanogaster (Dme) 7297211 GI:19920862
Drosophila melanogaster (Dme) 7301600 GI:7301600
Homo sapiens (Hsa) Hs4557403
(SLC25A20)		 GI:4557403 O43772
Homo sapiens (Hsa) Hs18560286 GI:18560286
Homo sapiens (Hsa) Hs20482669 GI:20482669
Homo sapiens (Hsa) Hs22060368 GI:22060368
Saccharomyces cerevisiae (Sce) YBR104w
(S000000308)		 GI:6319580 P38087
Saccharomyces cerevisiae (Sce) YOR100c
(S000005626)		 GI:6324674 Q12289
Saccharomyces cerevisiae (Sce) YOR130c
(S000005656)		 GI:6324704 Q12375
Saccharomyces cerevisiae (Sce) YPR058w
(S000006262)		 GI:6325315 P32331
Schizosaccharomyces pombe (Spo) SPAC4G9.20c GI:19114613 Q10248
Schizosaccharomyces pombe (Spo) SPBC29A3.11c GI:19112631 O59674
Arabidopsis thaliana (Ath) At2g33820 GI:15226171
Arabidopsis thaliana (Ath) At5g46800 GI:9758516
Caenorhabditis elegans (Cel) CE06272 GI:17562944
Caenorhabditis elegans (Cel) CE28408
(WBGene00000996)		 GI:17539560 Q27257
Drosophila melanogaster (Dme) 7295910
(FBgn0019830)		 GI:17137310
Drosophila melanogaster (Dme) 7297211 GI:19920862
Drosophila melanogaster (Dme) 7301600 GI:7301600
Homo sapiens (Hsa) Hs4557403
(SLC25A20)		 GI:4557403 O43772
Homo sapiens (Hsa) Hs18560286 GI:18560286
Homo sapiens (Hsa) Hs20482669 GI:20482669
Homo sapiens (Hsa) Hs22060368 GI:22060368
Saccharomyces cerevisiae (Sce) YBR104w
(S000000308)		 GI:6319580 P38087
Saccharomyces cerevisiae (Sce) YOR100c
(S000005626)		 GI:6324674 Q12289
Saccharomyces cerevisiae (Sce) YOR130c
(S000005656)		 GI:6324704 Q12375
Saccharomyces cerevisiae (Sce) YPR058w
(S000006262)		 GI:6325315 P32331
Schizosaccharomyces pombe (Spo) SPAC4G9.20c GI:19114613 Q10248
Schizosaccharomyces pombe (Spo) SPBC29A3.11c GI:19112631 O59674


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005739 mitochondrion C
IDA
AthAt5g46800
SceS000006262
S000000308
S000005626
SpoSPBC29A3.11c
GO:0005740 mitochondrial envelope C
IDA
SceS000005656
ISS
DmeFBgn0019830
NAS
DmeFBgn0019830
GO:0005743 mitochondrial inner membrane C
EXP
HsaSLC25A20
IDA
SceS000005626
ISS
AthAt2g33820
At5g46800
DmeFBgn0019830
SpoSPAC4G9.20c
SPBC29A3.11c
GO:0009507 chloroplast C
IDA
AthAt5g46800
GO:0009536 plastid C
IDA
AthAt5g46800
GO:0000064 L-ornithine transmembrane transporter
activity		 F
IDA
SceS000005656
IGI
AthAt2g33820
GO:0005215 transporter activity F
ISS
DmeFBgn0019830
SpoSPAC4G9.20c
NAS
DmeFBgn0019830
GO:0005290 L-histidine transmembrane transporter
activity		 F
IDA
AthAt2g33820
GO:0005342 organic acid transmembrane transporter
activity		 F
IGI
SceS000000308
S000006262
ISS
SceS000000308
S000006262
GO:0005476 carnitine:acyl carnitine antiporter
activity		 F
IDA
SceS000005626
ISS
DmeFBgn0019830
GO:0005488 binding F
ISS
AthAt5g46800
At2g33820
GO:0015181 arginine transmembrane transporter
activity		 F
IDA
AthAt2g33820
GO:0015189 L-lysine transmembrane transporter
activity		 F
IDA
AthAt2g33820
GO:0015227 acyl carnitine transporter activity F
EXP
HsaSLC25A20
GO:0022857 transmembrane transporter activity F
NAS
SpoSPAC4G9.20c
GO:0046943 carboxylic acid transmembrane transporter
activity		 F
ISS
SpoSPBC29A3.11c
GO:0000066 mitochondrial ornithine transport P
IDA
SceS000005656
GO:0006082 organic acid metabolic process P
RCA
SceS000006262
S000005656
GO:0006519 cellular amino acid and derivative metabolic
process		 P
RCA
SceS000005656
S000006262
GO:0006526 arginine biosynthetic process P
IMP
SceS000005656
GO:0006631 fatty acid metabolic process P
IDA
SceS000005626
GO:0006725 cellular aromatic compound metabolic
process		 P
RCA
SceS000006262
S000005656
GO:0006807 nitrogen compound metabolic process P
RCA
SceS000005656
S000006262
GO:0006810 transport P
ISS
AthAt5g46800
GO:0006839 mitochondrial transport P
IDA
AthAt5g46800
IGI
SceS000000308
S000006262
ISS
AthAt5g46800
At2g33820
DmeFBgn0019830
SpoSPAC4G9.20c
SPBC29A3.11c
GO:0006844 acyl carnitine transport P
ISS
DmeFBgn0019830
GO:0006853 carnitine shuttle P
EXP
HsaSLC25A20
GO:0006911 phagocytosis, engulfment P
IMP
DmeFBgn0019830
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00000996
GO:0015822 ornithine transport P
IGI
AthAt5g46800
GO:0015879 carnitine transport P
ISS
DmeFBgn0019830
GO:0046320 regulation of fatty acid oxidation P
EXP
HsaSLC25A20
GO:0046942 carboxylic acid transport P
ISS
SpoSPBC29A3.11c
GO:0055085 transmembrane transport P
IGI
SceS000000308
ISS
SceS000000308

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
56330

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) SLC25A2 GI:13994341 Q9BXI2
Pan troglodytes (Ptr) SLC25A2 GI:55625156
Canis familiaris (Cfa) SLC25A2 GI:57043479
Mus musculus (Mmu) Slc25a2
(MGI:2137907)		 GI:149269722 Q99ML6
Rattus norvegicus (Rno) Slc25a2 GI:27682801
Saccharomyces cerevisiae (Sce) ORT1
(S000005656)		 GI:6324704 Q12375
Kluyveromyces lactis (Kla) KLLA0E02772g GI:50308145
Eremothecium gossypii (Ego) AGOS_AFR146W GI:45198664
Magnaporthe grisea (Mgr) MGG_01584 GI:39951883
Neurospora crassa (Ncr) NCU02802.1 GI:32419024


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005739 mitochondrion C
IDA
MmuMGI:2137907
GO:0005740 mitochondrial envelope C
IDA
SceS000005656
GO:0000064 L-ornithine transmembrane transporter
activity		 F
IDA
SceS000005656
NAS
HsaSLC25A2
GO:0003674 molecular_function F
ND
MmuMGI:2137907
GO:0000066 mitochondrial ornithine transport P
IDA
SceS000005656
NAS
HsaSLC25A2
GO:0006082 organic acid metabolic process P
RCA
SceS000005656
GO:0006519 cellular amino acid and derivative metabolic
process		 P
RCA
SceS000005656
GO:0006526 arginine biosynthetic process P
IMP
SceS000005656
GO:0006725 cellular aromatic compound metabolic
process		 P
RCA
SceS000005656
GO:0006807 nitrogen compound metabolic process P
RCA
SceS000005656
GO:0008150 biological_process P
ND
MmuMGI:2137907

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_3428

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga15065 ENSANGP00000007451
Ashbya gossypii (Ago) ago3338 AFR146W
Arabidopsis thaliana (Ath) ath10425 At2g33820.1
Caenorhabditis elegans (Cel) cel15231 T10F2.2
(CE02041;
WBGene00020422)
Candida glabrata (Cgl) cgl3967 CAGL0K10362g
Cryptococcus neoformans (Cne) cne2842 183.m01800
Cryptococcus neoformans (Cne) cne3921 185.m02508
Debaryomyces hansenii (Dha) dha6341 DEHA0G14388g
Drosophila melanogaster (Dme) dme17281 CG1628-PB
(FBgn0030218)
Danio rerio (Dre) dre28139 ENSDARP00000021972
Danio rerio (Dre) dre18877 ENSDARP00000049986
Takifugu rubripes (Fru) fru29968 SINFRUP00000134315
Takifugu rubripes (Fru) fru29969 SINFRUP00000173721
Gallus gallus (Gga) gga3029 ENSGALP00000027466
(SLC25A15)		 Q5ZIW6
Gallus gallus (Gga) gga3030 ENSGALP00000027467
(SLC25A15)		 Q5ZIW6
Homo sapiens (Hsa) hsa25891 ENSP00000239451
(SLC25A2)		 Q9BXI2
Homo sapiens (Hsa) hsa8708 ENSP00000342267
(SLC25A15)		 Q9Y619
Kluyveromyces lactis (Kla) kla3072 KLLA0E02772g
Mus musculus (Mmu) mmu25730 ENSMUSP00000033871
(MGI:1342274)		 Q9WVD5
Neurospora crassa (Ncr) ncr2712 NCU02802.2
Rattus norvegicus (Rno) rno12686 ENSRNOP00000016043
(RGD:1311488)
Rattus norvegicus (Rno) rno12687 ENSRNOP00000045952
(RGD:1311488)		 Q7TPA1
Saccharomyces cerevisiae (Sce) sce5867 YOR130C
(S000005656)
Yarrowia lipolytica (Yli) yli2986 YALI0D06798g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005739 mitochondrion C
IDA
MmuMGI:1342274
GO:0005740 mitochondrial envelope C
IDA
SceS000005656
ISS
DmeFBgn0030218
GO:0005743 mitochondrial inner membrane C
IDA
MmuMGI:1342274
ISS
AthAt2g33820
DmeFBgn0030218
NAS
DmeFBgn0030218
GO:0000064 L-ornithine transmembrane transporter
activity		 F
IDA
SceS000005656
IGI
AthAt2g33820
ISS
DmeFBgn0030218
NAS
DmeFBgn0030218
GO:0005290 L-histidine transmembrane transporter
activity		 F
IDA
AthAt2g33820
GO:0005488 binding F
ISS
AthAt2g33820
GO:0015171 amino acid transmembrane transporter
activity		 F
ISS
DmeFBgn0030218
GO:0015181 arginine transmembrane transporter
activity		 F
IDA
AthAt2g33820
GO:0015189 L-lysine transmembrane transporter
activity		 F
IDA
AthAt2g33820
GO:0022857 transmembrane transporter activity F
ISS
DmeFBgn0030218
NAS
DmeFBgn0030218
GO:0000066 mitochondrial ornithine transport P
IDA
SceS000005656
ISS
DmeFBgn0030218
GO:0003333 amino acid transmembrane transport P
ISS
DmeFBgn0030218
GO:0006082 organic acid metabolic process P
RCA
SceS000005656
GO:0006519 cellular amino acid and derivative metabolic
process		 P
RCA
SceS000005656
GO:0006526 arginine biosynthetic process P
IMP
SceS000005656
GO:0006725 cellular aromatic compound metabolic
process		 P
RCA
SceS000005656
GO:0006807 nitrogen compound metabolic process P
RCA
SceS000005656
GO:0006839 mitochondrial transport P
ISS
AthAt2g33820

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPBC29A3.11c
(O59674)		 YOR130C
(S000005656)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005739 mitochondrion C
IDA
SpoSPBC29A3.11c
GO:0005740 mitochondrial envelope C
IDA
SceS000005656
GO:0005743 mitochondrial inner membrane C
ISS
SpoSPBC29A3.11c
GO:0000064 L-ornithine transmembrane transporter
activity		 F
IDA
SceS000005656
GO:0046943 carboxylic acid transmembrane transporter
activity		 F
ISS
SpoSPBC29A3.11c
GO:0000066 mitochondrial ornithine transport P
IDA
SceS000005656
GO:0006082 organic acid metabolic process P
RCA
SceS000005656
GO:0006519 cellular amino acid and derivative metabolic
process		 P
RCA
SceS000005656
GO:0006526 arginine biosynthetic process P
IMP
SceS000005656
GO:0006725 cellular aromatic compound metabolic
process		 P
RCA
SceS000005656
GO:0006807 nitrogen compound metabolic process P
RCA
SceS000005656
GO:0006839 mitochondrial transport P
ISS
SpoSPBC29A3.11c
GO:0046942 carboxylic acid transport P
ISS
SpoSPBC29A3.11c

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