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Search term: YOR196C

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name LIP5
SGD link S000005722
Alternative ID YOR196C
Description Protein involved in biosynthesis of the coenzyme lipoic acid, has similarity to E. coli lipoic acid synthase
Synonyms YOR196C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG2672 ACDHYP-

KOGs classification KOGs description
METABOLISM Lipoate synthase

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At2g20860 GI:15226412
Arabidopsis thaliana (Ath) At5g08410 GI:10178283
Caenorhabditis elegans (Cel) CE01031
(WBGene00010809)		 GI:17554236
Drosophila melanogaster (Dme) 7296306
(FBgn0029158)		 GI:17737685
Homo sapiens (Hsa) Hs20535296 GI:20535296
Saccharomyces cerevisiae (Sce) YOR196c
(S000005722)		 GI:6324770 P32875
Schizosaccharomyces pombe (Spo) SPBC8D2.15 GI:19112369 O13642
Schizosaccharomyces pombe (Spo) SPBPI050 GI:19112339


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005739 mitochondrion C
IDA
AthAt2g20860
SceS000005722
SpoSPBC8D2.15
ISS
DmeFBgn0029158
SpoSPBC8D2.15
GO:0005759 mitochondrial matrix C
IDA
AthAt2g20860
GO:0009507 chloroplast C
IDA
AthAt5g08410
GO:0016992 lipoate synthase activity F
ISA
SceS000005722
ISS
SpoSPBC8D2.15
GO:0017140 lipoic acid synthase activity F
IGI
AthAt2g20860
ISS
DmeFBgn0029158
GO:0030385 ferredoxin:thioredoxin reductase
activity		 F
ISS
AthAt5g08410
GO:0002119 nematode larval development P
IMP
CelWBGene00010809
GO:0006546 glycine catabolic process P
TAS
AthAt2g20860
GO:0009105 lipoic acid biosynthetic process P
ISS
DmeFBgn0029158
TAS
AthAt2g20860
GO:0009107 lipoate biosynthetic process P
ISS
SpoSPBC8D2.15
GO:0009249 protein lipoylation P
IMP
SceS000005722
ISS
SpoSPBC8D2.15
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00010809
GO:0019684 photosynthesis, light reaction P
ISS
AthAt5g08410
GO:0040007 growth P
IMP
CelWBGene00010809
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00010809

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
4997

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) LIAS GI:37577166
Pan troglodytes (Ptr) LIAS GI:114593623
Canis familiaris (Cfa) LIAS GI:57048078
Mus musculus (Mmu) Lias
(MGI:1934604)		 GI:13277380 Q8CCZ4
Rattus norvegicus (Rno) Lias
(RGD:1307270)		 GI:58865650
Gallus gallus (Gga) LIAS GI:118090596
Drosophila melanogaster (Dme) Las
(FBgn0029158)		 GI:17737685
Anopheles gambiae (Aga) AgaP_AGAP010568 GI:158293213
Caenorhabditis elegans (Cel) M01F1.3
(CE01031;
WBGene00010809)		 GI:32564533
Schizosaccharomyces pombe (Spo) SPBC8D2.15 GI:19112369 O13642
Saccharomyces cerevisiae (Sce) LIP5
(S000005722)		 GI:6324770 P32875
Kluyveromyces lactis (Kla) KLLA0F00836g GI:50310195
Eremothecium gossypii (Ego) AGOS_AGR231C GI:45201327
Magnaporthe grisea (Mgr) MGG_02691 GI:145610133
Neurospora crassa (Ncr) NCU00565.1 GI:32408527
Arabidopsis thaliana (Ath) AT5G08415 GI:18415808
Oryza sativa (Osa) Os05g0511500 GI:115464833
Oryza sativa (Osa) Os01g0769100 GI:115440181
Plasmodium falciparum (Pfa) MAL13P1.220 GI:124513608


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
HsaLIAS
GO:0005737 cytoplasm C
IDA
HsaLIAS
GO:0005739 mitochondrion C
IDA
HsaLIAS
MmuMGI:1934604
SceS000005722
SpoSPBC8D2.15
ISS
DmeFBgn0029158
HsaLIAS
PfaMAL13P1.220
SpoSPBC8D2.15
GO:0020011 apicoplast C
ISS
PfaMAL13P1.220
GO:0016992 lipoate synthase activity F
ISA
SceS000005722
ISS
SpoSPBC8D2.15
GO:0017140 lipoic acid synthase activity F
IGI
MmuMGI:1934604
ISS
AthAT5G08415
DmeFBgn0029158
HsaLIAS
PfaMAL13P1.220
GO:0002119 nematode larval development P
IMP
CelWBGene00010809
GO:0006954 inflammatory response P
IMP
MmuMGI:1934604
ISS
HsaLIAS
GO:0006979 response to oxidative stress P
IMP
MmuMGI:1934604
ISS
HsaLIAS
GO:0009105 lipoic acid biosynthetic process P
IGI
MmuMGI:1934604
ISS
AthAT5G08415
DmeFBgn0029158
HsaLIAS
GO:0009107 lipoate biosynthetic process P
ISS
SpoSPBC8D2.15
GO:0009249 protein lipoylation P
IMP
SceS000005722
ISS
SpoSPBC8D2.15
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00010809
GO:0032496 response to lipopolysaccharide P
IMP
MmuMGI:1934604
ISS
HsaLIAS
GO:0040007 growth P
IMP
CelWBGene00010809
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00010809

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_1007

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga7533 ENSANGP00000016313
Ashbya gossypii (Ago) ago4542 AGR231C
Arabidopsis thaliana (Ath) ath8969 At2g20860.1
Arabidopsis thaliana (Ath) ath23061 At5g08415.1
Caenorhabditis elegans (Cel) cel12788 M01F1.3
(CE01031;
WBGene00010809)
Candida glabrata (Cgl) cgl2993 CAGL0I10923g
Debaryomyces hansenii (Dha) dha6595 DEHA0G20031g
Drosophila melanogaster (Dme) dme10415 CG5231-PA
(FBgn0029158)
Danio rerio (Dre) dre512 ENSDARP00000035286
(LOC572803)
Escherichia coli (Eco) eco617 16128611
Takifugu rubripes (Fru) fru6490 SINFRUP00000142420
Gallus gallus (Gga) gga18194 ENSGALP00000023093
(LIAS)
Homo sapiens (Hsa) hsa24028 ENSP00000261434
(LIAS)		 O43766
Kluyveromyces lactis (Kla) kla4116 KLLA0F00836g
Mus musculus (Mmu) mmu20146 ENSMUSP00000031101
(MGI:1934604)		 Q99M04
Neurospora crassa (Ncr) ncr549 NCU00565.2
Oryza sativa (Osa) osa10075 2718.m00128
Oryza sativa (Osa) osa23571 3732.m00167
Oryza sativa (Osa) osa46948 5540.m00083
Oryza sativa (Osa) osa49029 5833.m00140
Oryza sativa (Osa) osa49130 5835.m00180
Oryza sativa (Osa) osa82832 8282.m00172
Plasmodium falciparum (Pfa) pfa3963 MAL13P1.220
Rattus norvegicus (Rno) rno10379 ENSRNOP00000003779
(RGD:1307270)		 Q5XIH4
Saccharomyces cerevisiae (Sce) sce5942 YOR196C
(S000005722)
Schizosaccharomyces pombe (Spo) spo2536 SPBC8D2.15 O13642
Yarrowia lipolytica (Yli) yli4300 YALI0E10571g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005739 mitochondrion C
IDA
AthAt2g20860
MmuMGI:1934604
SceS000005722
SpoSPBC8D2.15
ISS
DmeFBgn0029158
PfaMAL13P1.220
SpoSPBC8D2.15
GO:0005759 mitochondrial matrix C
IDA
AthAt2g20860
GO:0020011 apicoplast C
ISS
PfaMAL13P1.220
GO:0016992 lipoate synthase activity F
ISA
SceS000005722
ISS
SpoSPBC8D2.15
GO:0017140 lipoic acid synthase activity F
IGI
AthAt2g20860
MmuMGI:1934604
ISS
AthAT5G08415
DmeFBgn0029158
PfaMAL13P1.220
GO:0002119 nematode larval development P
IMP
CelWBGene00010809
GO:0006546 glycine catabolic process P
TAS
AthAt2g20860
GO:0006954 inflammatory response P
IMP
MmuMGI:1934604
GO:0006979 response to oxidative stress P
IMP
MmuMGI:1934604
GO:0009105 lipoic acid biosynthetic process P
IGI
MmuMGI:1934604
ISS
AthAT5G08415
DmeFBgn0029158
TAS
AthAt2g20860
GO:0009107 lipoate biosynthetic process P
ISS
SpoSPBC8D2.15
GO:0009249 protein lipoylation P
IMP
SceS000005722
ISS
SpoSPBC8D2.15
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00010809
GO:0032496 response to lipopolysaccharide P
IMP
MmuMGI:1934604
GO:0040007 growth P
IMP
CelWBGene00010809
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00010809

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPBC8D2.15
(O13642)		 YOR196C
(S000005722)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005739 mitochondrion C
IDA
SceS000005722
SpoSPBC8D2.15
ISS
SpoSPBC8D2.15
GO:0016992 lipoate synthase activity F
ISA
SceS000005722
ISS
SpoSPBC8D2.15
GO:0009107 lipoate biosynthetic process P
ISS
SpoSPBC8D2.15
GO:0009249 protein lipoylation P
IMP
SceS000005722
ISS
SpoSPBC8D2.15

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GO info in one table:

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