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Search term: YOR231W


Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name MKK1
SGD link S000005757
Alternative ID YOR231W
Description Mitogen-activated kinase kinase involved in protein kinase C signaling pathway that controls cell integrity; upon activation by Bck1p phosphorylates downstream target, Slt2p; functionally redundant with Mkk2p
Synonyms YOR231W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

Search for gene by ID or name:

Query species:

Include wild-cards:   

Search for GO info:  

GO info in one table:


KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG0581 ACDHYP-

KOGs classification KOGs description
CELLULAR PROCESSES AND SIGNALING Mitogen-activated protein kinase kinase (MAP2K)

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At1g18350 GI:15221060
Arabidopsis thaliana (Ath) At1g32320 GI:15223165
Arabidopsis thaliana (Ath) At1g51660 GI:15217998
Arabidopsis thaliana (Ath) At1g73500 GI:15219482
Arabidopsis thaliana (Ath) At3g06230 GI:15230671
Arabidopsis thaliana (Ath) At3g21220 GI:15232491
Arabidopsis thaliana (Ath) At4g26070 GI:15236108
Arabidopsis thaliana (Ath) At4g29810 GI:15233715
Arabidopsis thaliana (Ath) At5g40440 GI:15242705
Arabidopsis thaliana (Ath) At5g56580 GI:15241264
Caenorhabditis elegans (Cel) CE25437
(WBGene00003186)
GI:17508425 Q10664
Caenorhabditis elegans (Cel) CE27902
(WBGene00017098)
GI:17506463
Drosophila melanogaster (Dme) 7291037
(FBgn0010269)
GI:17737298
Homo sapiens (Hsa) Hs13489054
(MAP2K2)
GI:13489054 P36507
Homo sapiens (Hsa) Hs18566753 GI:18566753
Homo sapiens (Hsa) Hs21729895 GI:1616779 Q13163
Homo sapiens (Hsa) Hs21729897 GI:21729897
Homo sapiens (Hsa) Hs21729899 GI:21729899
Homo sapiens (Hsa) Hs4506101 GI:4506101 Q13163
Homo sapiens (Hsa) Hs5579478
(MAP2K1)
GI:5579478 Q02750
Saccharomyces cerevisiae (Sce) YDL159w
(S000002318)
GI:6320042 P06784
Saccharomyces cerevisiae (Sce) YJL128c
(S000003664)
GI:6322333 P08018
Saccharomyces cerevisiae (Sce) YOR231w
(S000005757)
GI:6324805 P32490
Saccharomyces cerevisiae (Sce) YPL140c
(S000006061)
GI:6325117 P32491
Schizosaccharomyces pombe (Spo) SPAC1D4.13 GI:19113938 P10506
Schizosaccharomyces pombe (Spo) SPBC409.07c GI:19112249 P33886
Schizosaccharomyces pombe (Spo) SPBC543.07 GI:19113587 Q9Y884
Arabidopsis thaliana (Ath) At1g18350 GI:15221060
Arabidopsis thaliana (Ath) At1g32320 GI:15223165
Arabidopsis thaliana (Ath) At1g51660 GI:15217998
Arabidopsis thaliana (Ath) At1g73500 GI:15219482
Arabidopsis thaliana (Ath) At3g06230 GI:15230671
Arabidopsis thaliana (Ath) At3g21220 GI:15232491
Arabidopsis thaliana (Ath) At4g26070 GI:15236108
Arabidopsis thaliana (Ath) At4g29810 GI:15233715
Arabidopsis thaliana (Ath) At5g40440 GI:15242705
Arabidopsis thaliana (Ath) At5g56580 GI:15241264
Caenorhabditis elegans (Cel) CE25437
(WBGene00003186)
GI:17508425 Q10664
Caenorhabditis elegans (Cel) CE27902
(WBGene00017098)
GI:17506463
Drosophila melanogaster (Dme) 7291037
(FBgn0010269)
GI:17737298
Homo sapiens (Hsa) Hs13489054
(MAP2K2)
GI:13489054 P36507
Homo sapiens (Hsa) Hs18566753 GI:18566753
Homo sapiens (Hsa) Hs21729895 GI:1616779 Q13163
Homo sapiens (Hsa) Hs21729897 GI:21729897
Homo sapiens (Hsa) Hs21729899 GI:21729899
Homo sapiens (Hsa) Hs4506101 GI:4506101 Q13163
Homo sapiens (Hsa) Hs5579478
(MAP2K1)
GI:5579478 Q02750
Saccharomyces cerevisiae (Sce) YDL159w
(S000002318)
GI:6320042 P06784
Saccharomyces cerevisiae (Sce) YJL128c
(S000003664)
GI:6322333 P08018
Saccharomyces cerevisiae (Sce) YOR231w
(S000005757)
GI:6324805 P32490
Saccharomyces cerevisiae (Sce) YPL140c
(S000006061)
GI:6325117 P32491
Schizosaccharomyces pombe (Spo) SPAC1D4.13 GI:19113938 P10506
Schizosaccharomyces pombe (Spo) SPBC409.07c GI:19112249 P33886
Schizosaccharomyces pombe (Spo) SPBC543.07 GI:19113587 Q9Y884


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
AthAt4g26070
GO:0005576 extracellular region C
NAS
HsaMAP2K2
GO:0005622 intracellular C
TAS
SceS000006061
GO:0005634 nucleus C
IDA
AthAt1g51660
SpoSPAC1D4.13
SPBC409.07c
SPBC543.07
GO:0005737 cytoplasm C
IDA
AthAt1g51660
At4g29810
SceS000002318
S000003664
SpoSPBC409.07c
SPBC543.07
GO:0005829 cytosol C
EXP
HsaMAP2K1
MAP2K2
IDA
SpoSPAC1D4.13
SPBC543.07
SPBC409.07c
GO:0005886 plasma membrane C
IDA
AthAt4g29810
GO:0005934 cellular bud tip C
IDA
SceS000003664
S000005757
GO:0005935 cellular bud neck C
IDA
SceS000003664
GO:0030428 cell septum C
IDA
SpoSPBC543.07
GO:0043332 mating projection tip C
IDA
SceS000002318
GO:0004672 protein kinase activity F
TAS
HsaMAP2K1
GO:0004674 protein serine/threonine kinase
activity
F
EXP
HsaMAP2K1
MAP2K2
NAS
HsaMAP2K2
RCA
SceS000005757
S000006061
S000003664
S000002318
GO:0004702 receptor signaling protein serine/threonine kinase
activity
F
NAS
DmeFBgn0010269
GO:0004707 MAP kinase activity F
NAS
DmeFBgn0010269
GO:0004708 MAP kinase kinase activity F
IDA
AthAt5g56580
At4g26070
At1g51660
At1g73500
At4g29810
At5g40440
SceS000002318
IGI
SpoSPBC409.07c
IMP
SceS000003664
ISS
AthAt1g51660
At3g21220
At4g29810
At5g40440
DmeFBgn0010269
SceS000006061
S000003664
S000005757
NAS
DmeFBgn0010269
TAS
AthAt1g18350
At3g06230
At4g26070
At5g56580
At1g32320
At1g73500
At4g29810
DmeFBgn0010269
SpoSPAC1D4.13
SPBC543.07
GO:0005078 MAP-kinase scaffold activity F
IPI
SceS000003664
GO:0005515 protein binding F
IPI
AthAt4g26070
HsaMAP2K2
MAP2K1
SpoSPAC1D4.13
SPBC409.07c
GO:0005524 ATP binding F
ISS
SpoSPBC409.07c
NAS
HsaMAP2K2
GO:0016301 kinase activity F
IDA
AthAt1g18350
ISS
AthAt3g06230
At1g51660
At3g21220
At4g26070
At1g32320
At5g56580
At1g18350
At1g73500
At4g29810
GO:0030295 protein kinase activator activity F
IDA
AthAt1g73500
GO:0000003 reproduction P
IMP
CelWBGene00003186
WBGene00017098
GO:0000165 MAPKKK cascade P
IC
AthAt1g51660
At4g26070
At4g29810
IDA
SpoSPBC543.07
IGI
AthAt4g29810
ISS
AthAt5g40440
NAS
DmeFBgn0010269
SpoSPAC1D4.13
GO:0000169 activation of MAPK activity involved in
osmosensory signaling pathway
P
IMP
SceS000003664
GO:0000196 MAPKKK cascade involved in cell wall
biogenesis
P
IGI
SceS000002318
GO:0000208 nuclear translocation of MAPK involved in
osmosensory signaling pathway
P
IMP
SceS000003664
GO:0000751 cell cycle arrest in response to
pheromone
P
TAS
SpoSPAC1D4.13
GO:0001101 response to acid P
RCA
SceS000005757
GO:0001402 signal transduction involved in filamentous
growth
P
IMP
SceS000002318
GO:0001403 invasive growth in response to glucose
limitation
P
IGI
SceS000002318
IMP
SceS000002318
GO:0001703 gastrulation with mouth forming
first
P
IMP
CelWBGene00003186
GO:0002009 morphogenesis of an epithelium P
IMP
CelWBGene00003186
GO:0002119 nematode larval development P
IMP
CelWBGene00017098
WBGene00003186
GO:0002229 defense response to oomycetes P
IMP
AthAt1g18350
GO:0002237 response to molecule of bacterial
origin
P
IDA
AthAt4g26070
GO:0006414 translational elongation P
RCA
SceS000005757
GO:0006468 protein amino acid phosphorylation P
IDA
SceS000002318
IGI
SpoSPBC409.07c
IMP
SceS000002318
S000003664
ISS
SceS000006061
S000005757
SpoSPAC1D4.13
SPBC543.07
NAS
DmeFBgn0010269
HsaMAP2K2
TAS
DmeFBgn0010269
GO:0006793 phosphorus metabolic process P
RCA
SceS000002318
S000003664
GO:0006883 cellular sodium ion homeostasis P
NAS
SpoSPBC543.07
GO:0006928 cellular component movement P
TAS
HsaMAP2K1
GO:0006935 chemotaxis P
TAS
HsaMAP2K1
GO:0006952 defense response P
IMP
CelWBGene00003186
GO:0006970 response to osmotic stress P
RCA
SceS000003664
TAS
SpoSPBC409.07c
GO:0006972 hyperosmotic response P
IMP
SceS000003664
GO:0006984 ER-nucleus signaling pathway P
RCA
SceS000006061
S000005757
GO:0006986 response to unfolded protein P
RCA
SceS000005757
GO:0006995 cellular response to nitrogen starvation P
IGI
SpoSPAC1D4.13
GO:0007015 actin filament organization P
IMP
SceS000003664
GO:0007047 cellular cell wall organization P
NAS
SpoSPBC543.07
GO:0007050 cell cycle arrest P
IMP
HsaMAP2K1
GO:0007124 pseudohyphal growth P
IMP
SceS000002318
GO:0007165 signal transduction P
IGI
DmeFBgn0010269
IMP
DmeFBgn0010269
SceS000006061
S000005757
TAS
HsaMAP2K1
GO:0007173 epidermal growth factor receptor signaling
pathway
P
NAS
DmeFBgn0010269
GO:0007231 osmosensory signaling pathway P
IMP
SceS000003664
GO:0007243 intracellular protein kinase cascade P
RCA
SceS000005757
GO:0007264 small GTPase mediated signal transduction P
EXP
HsaMAP2K2
MAP2K1
GO:0007265 Ras protein signal transduction P
EXP
HsaMAP2K1
MAP2K2
IGI
CelWBGene00003186
GO:0007298 border follicle cell migration P
IGI
DmeFBgn0010269
GO:0007346 regulation of mitotic cell cycle P
IMP
SpoSPBC409.07c
GO:0007369 gastrulation P
IMP
CelWBGene00003186
GO:0008285 negative regulation of cell proliferation P
IDA
HsaMAP2K1
GO:0008293 torso signaling pathway P
NAS
DmeFBgn0010269
GO:0008360 regulation of cell shape P
NAS
SpoSPBC543.07
GO:0008592 regulation of Toll signaling pathway P
NAS
DmeFBgn0010269
GO:0008595 anterior/posterior axis specification,
embryo
P
TAS
DmeFBgn0010269
GO:0009409 response to cold P
IDA
AthAt4g29810
IMP
AthAt4g29810
GO:0009414 response to water deprivation P
IMP
AthAt4g26070
GO:0009611 response to wounding P
IEP
AthAt4g26070
At1g73500
GO:0009628 response to abiotic stimulus P
TAS
AthAt4g26070
GO:0009631 cold acclimation P
IMP
AthAt4g29810
GO:0009651 response to salt stress P
IDA
AthAt4g29810
IGI
AthAt4g29810
IMP
AthAt1g73500
At4g29810
GO:0009693 ethylene biosynthetic process P
IDA
AthAt1g73500
GO:0009790 embryo development P
IMP
CelWBGene00003186
GO:0009792 embryo development ending in birth or egg
hatching
P
IMP
CelWBGene00003186
GO:0009814 defense response, incompatible
interaction
P
IGI
AthAt4g26070
At4g29810
IMP
AthAt3g21220
At5g40440
At1g51660
GO:0009862 systemic acquired resistance, salicylic acid
mediated signaling pathway
P
IMP
AthAt1g18350
GO:0009864 induced systemic resistance, jasmonic acid
mediated signaling pathway
P
IEP
AthAt5g40440
GO:0009866 induced systemic resistance, ethylene mediated
signaling pathway
P
IEP
AthAt5g40440
GO:0009873 ethylene mediated signaling pathway P
IMP
AthAt1g73500
GO:0009926 auxin polar transport P
IMP
AthAt1g18350
GO:0010120 camalexin biosynthetic process P
IDA
AthAt1g73500
GO:0010227 floral organ abscission P
IMP
AthAt1g51660
At3g21220
GO:0010525 regulation of transposition, RNA-mediated P
IMP
SceS000002318
GO:0018996 molting cycle, collagen and cuticulin-based
cuticle
P
IMP
CelWBGene00017098
GO:0019953 sexual reproduction P
RCA
SceS000002318
GO:0030242 peroxisome degradation P
IGI
SceS000006061
S000005757
GO:0030421 defecation P
IMP
CelWBGene00003186
GO:0030447 filamentous growth P
RCA
SceS000002318
GO:0032005 regulation of conjugation with cellular fusion by
signal transduction
P
IGI
SpoSPAC1D4.13
GO:0033205 cell cycle cytokinesis P
NAS
SpoSPBC543.07
GO:0040007 growth P
IMP
CelWBGene00003186
WBGene00017098
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00003186
WBGene00017098
GO:0040011 locomotion P
IMP
CelWBGene00017098
GO:0040025 vulval development P
IGI
CelWBGene00003186
GO:0040026 positive regulation of vulval development P
IMP
CelWBGene00003186
GO:0040035 hermaphrodite genitalia development P
IMP
CelWBGene00003186
WBGene00017098
GO:0042386 hemocyte differentiation P
IGI
DmeFBgn0010269
GO:0042542 response to hydrogen peroxide P
IDA
AthAt4g26070
GO:0042742 defense response to bacterium P
IDA
AthAt4g26070
IMP
AthAt1g18350
GO:0043555 regulation of translation in response to
stress
P
IMP
SpoSPBC409.07c
GO:0045500 sevenless signaling pathway P
NAS
DmeFBgn0010269
GO:0045941 positive regulation of transcription P
IEP
AthAt1g73500
GO:0046685 response to arsenic P
IMP
SpoSPBC409.07c
GO:0046777 protein amino acid autophosphorylation P
IDA
AthAt1g73500
GO:0050850 positive regulation of calcium-mediated
signaling
P
IMP
SpoSPBC543.07
GO:0051403 stress-activated MAPK cascade P
TAS
SpoSPBC409.07c
GO:0061161 positive regulation of establishment of bipolar
cell polarity resulting in cell
shape
P
IMP
SpoSPBC543.07
SPBC409.07c
GO:0070301 cellular response to hydrogen peroxide P
IMP
SpoSPBC409.07c
GO:0070314 G1 to G0 transition P
IMP
SpoSPBC409.07c
GO:0071507 MAPKKK cascade involved in conjugation with
cellular fusion
P
IDA
SceS000002318
IPI
SceS000002318
GO:0071508 activation of MAPK activity involved in
conjugation with cellular fusion
P
IDA
SceS000002318
IMP
SceS000002318
ISS
SceS000002318
GO:2000037 regulation of stomatal complex
patterning
P
IGI
AthAt1g51660
At3g21220
GO:2000038 regulation of stomatal complex
development
P
IGI
AthAt1g51660

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
117919

Species Gene ID NCBI link UniProt link
Canis familiaris (Cfa) LOC609559 GI:74000616
Schizosaccharomyces pombe (Spo) mkk1 GI:19113587
Saccharomyces cerevisiae (Sce) MKK1
(S000005757)
GI:6324805 P32490
Saccharomyces cerevisiae (Sce) MKK2
(S000006061)
GI:6325117 P32491
Kluyveromyces lactis (Kla) KLLA0D07304g GI:50306823
Eremothecium gossypii (Ego) AGOS_ACR117W GI:45185803
Magnaporthe grisea (Mgr) MGG_06482 GI:39977159
Neurospora crassa (Ncr) NCU06419.1 GI:32411587


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005622 intracellular C
TAS
SceS000006061
GO:0005934 cellular bud tip C
IDA
SceS000005757
GO:0004674 protein serine/threonine kinase
activity
F
RCA
SceS000005757
S000006061
GO:0004708 MAP kinase kinase activity F
ISS
SceS000006061
S000005757
GO:0001101 response to acid P
RCA
SceS000005757
GO:0006414 translational elongation P
RCA
SceS000005757
GO:0006468 protein amino acid phosphorylation P
ISS
SceS000006061
S000005757
GO:0006984 ER-nucleus signaling pathway P
RCA
SceS000006061
S000005757
GO:0006986 response to unfolded protein P
RCA
SceS000005757
GO:0007165 signal transduction P
IMP
SceS000006061
S000005757
GO:0007243 intracellular protein kinase cascade P
RCA
SceS000005757
GO:0030242 peroxisome degradation P
IGI
SceS000006061
S000005757

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_11677

Species OrthoMCL
sequence
Model organism
protein page
UniProt link
Ashbya gossypii (Ago) ago1164 ACR117W
Candida glabrata (Cgl) cgl3154 CAGL0J03828g
Cryptococcus neoformans (Cne) cne3039 167.m03344
Debaryomyces hansenii (Dha) dha2192 DEHA0C17204g
Kluyveromyces lactis (Kla) kla2386 KLLA0D07304g
Neurospora crassa (Ncr) ncr6238 NCU06419.2
Saccharomyces cerevisiae (Sce) sce5978 YOR231W
(S000005757)
Saccharomyces cerevisiae (Sce) sce6299 YPL140C
(S000006061)
Schizosaccharomyces pombe (Spo) spo1701 SPBC543.07 Q9Y884
Yarrowia lipolytica (Yli) yli1283 YALI0B13178g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005622 intracellular C
TAS
SceS000006061
GO:0005634 nucleus C
IDA
SpoSPBC543.07
GO:0005737 cytoplasm C
IDA
SpoSPBC543.07
GO:0005829 cytosol C
IDA
SpoSPBC543.07
GO:0005934 cellular bud tip C
IDA
SceS000005757
GO:0030428 cell septum C
IDA
SpoSPBC543.07
GO:0004674 protein serine/threonine kinase
activity
F
RCA
SceS000005757
S000006061
GO:0004708 MAP kinase kinase activity F
ISS
SceS000006061
S000005757
TAS
SpoSPBC543.07
GO:0000165 MAPKKK cascade P
IDA
SpoSPBC543.07
GO:0001101 response to acid P
RCA
SceS000005757
GO:0006414 translational elongation P
RCA
SceS000005757
GO:0006468 protein amino acid phosphorylation P
ISS
SceS000006061
S000005757
SpoSPBC543.07
GO:0006883 cellular sodium ion homeostasis P
NAS
SpoSPBC543.07
GO:0006984 ER-nucleus signaling pathway P
RCA
SceS000006061
S000005757
GO:0006986 response to unfolded protein P
RCA
SceS000005757
GO:0007047 cellular cell wall organization P
NAS
SpoSPBC543.07
GO:0007165 signal transduction P
IMP
SceS000006061
S000005757
GO:0007243 intracellular protein kinase cascade P
RCA
SceS000005757
GO:0008360 regulation of cell shape P
NAS
SpoSPBC543.07
GO:0030242 peroxisome degradation P
IGI
SceS000006061
S000005757
GO:0033205 cell cycle cytokinesis P
NAS
SpoSPBC543.07
GO:0050850 positive regulation of calcium-mediated
signaling
P
IMP
SpoSPBC543.07
GO:0061161 positive regulation of establishment of bipolar
cell polarity resulting in cell
shape
P
IMP
SpoSPBC543.07

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Curated yeast ortholog results:

S. pombe
systematic ID
S. cerevisiae
systematic ID
SPBC543.07
(Q9Y884)
YOR231W
(S000005757)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SpoSPBC543.07
GO:0005737 cytoplasm C
IDA
SpoSPBC543.07
GO:0005829 cytosol C
IDA
SpoSPBC543.07
GO:0005934 cellular bud tip C
IDA
SceS000005757
GO:0030428 cell septum C
IDA
SpoSPBC543.07
GO:0004674 protein serine/threonine kinase
activity
F
RCA
SceS000005757
GO:0004708 MAP kinase kinase activity F
ISS
SceS000005757
TAS
SpoSPBC543.07
GO:0000165 MAPKKK cascade P
IDA
SpoSPBC543.07
GO:0001101 response to acid P
RCA
SceS000005757
GO:0006414 translational elongation P
RCA
SceS000005757
GO:0006468 protein amino acid phosphorylation P
ISS
SceS000005757
SpoSPBC543.07
GO:0006883 cellular sodium ion homeostasis P
NAS
SpoSPBC543.07
GO:0006984 ER-nucleus signaling pathway P
RCA
SceS000005757
GO:0006986 response to unfolded protein P
RCA
SceS000005757
GO:0007047 cellular cell wall organization P
NAS
SpoSPBC543.07
GO:0007165 signal transduction P
IMP
SceS000005757
GO:0007243 intracellular protein kinase cascade P
RCA
SceS000005757
GO:0008360 regulation of cell shape P
NAS
SpoSPBC543.07
GO:0030242 peroxisome degradation P
IGI
SceS000005757
GO:0033205 cell cycle cytokinesis P
NAS
SpoSPBC543.07
GO:0050850 positive regulation of calcium-mediated
signaling
P
IMP
SpoSPBC543.07
GO:0061161 positive regulation of establishment of bipolar
cell polarity resulting in cell
shape
P
IMP
SpoSPBC543.07

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