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Search term: YOR244W


Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name ESA1
SGD link S000005770
Alternative ID YOR244W
Description Catalytic subunit of the histone acetyltransferase complex (NuA4) that acetylates four conserved internal lysines of histone H4 N-terminal tail; required for cell cycle progression and transcriptional silencing at the rDNA locus
Synonyms YOR244W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:


KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG2747 ACDHYPE

KOGs classification KOGs description
INFORMATION STORAGE AND PROCESSING Histone acetyltransferase (MYST family)

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At5g09740 GI:15242493
Arabidopsis thaliana (Ath) At5g64610 GI:15237745
Caenorhabditis elegans (Cel) CE06262 GI:17562926
Caenorhabditis elegans (Cel) CE21225
(WBGene00007029)
GI:17564938 Q9TYU5
Caenorhabditis elegans (Cel) CE23850
(WBGene00010537)
GI:17508027 Q9U3C3
Caenorhabditis elegans (Cel) CE27246
(WBGene00021263)
GI:17555600 Q9BKX4
Caenorhabditis elegans (Cel) CE27818
(WBGene00007914)
GI:17505849 Q95ZX6
Drosophila melanogaster (Dme) 7290469 GI:4185890
Drosophila melanogaster (Dme) 7290646
(FBgn0014340)
GI:17530803
Drosophila melanogaster (Dme) 7291743 GI:7291743
Drosophila melanogaster (Dme) 7297249 GI:7297249
Drosophila melanogaster (Dme) 7301677 GI:7301677 Q9VAV6
Homo sapiens (Hsa) Hs14149875
(MYST1)
GI:14149875
Homo sapiens (Hsa) Hs20549811 GI:20549811
Homo sapiens (Hsa) Hs5454128 GI:5454128
Homo sapiens (Hsa) Hs5803098 GI:5803098
Homo sapiens (Hsa) Hs5901962
(MYST2)
GI:5901962 O95251
Homo sapiens (Hsa) Hs6912512 GI:6912512
Saccharomyces cerevisiae (Sce) YBL052c
(S000000148)
GI:6319419 P34218
Saccharomyces cerevisiae (Sce) YMR127c
(S000004734)
GI:6323775 P40963
Saccharomyces cerevisiae (Sce) YOR244w
(S000005770)
GI:6324818 Q08649
Schizosaccharomyces pombe (Spo) SPAC17G8.13c GI:19114648 Q10325
Schizosaccharomyces pombe (Spo) SPAC637.12c GI:19115542 O94446
Encephalitozoon cuniculi (Ecu) ECU09g1310 GI:19173251
Encephalitozoon cuniculi (Ecu) ECU10g0660 GI:19074675 Q8SR51


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000123 histone acetyltransferase complex C
IDA
HsaMYST2
ISS
SpoSPAC17G8.13c
GO:0000784 nuclear chromosome, telomeric region C
IC
SceS000004734
GO:0000790 nuclear chromatin C
IDA
SceS000004734
SpoSPAC17G8.13c
SPAC637.12c
GO:0000805 X chromosome C
TAS
DmeFBgn0014340
GO:0005634 nucleus C
IDA
AthAt5g09740
At5g64610
HsaMYST1
SpoSPAC637.12c
SPAC17G8.13c
GO:0005654 nucleoplasm C
IDA
HsaMYST2
GO:0005829 cytosol C
IDA
SpoSPAC17G8.13c
GO:0016456 X chromosome located dosage compensation complex,
transcription activating
C
NAS
DmeFBgn0014340
TAS
DmeFBgn0014340
GO:0032777 Piccolo NuA4 histone acetyltransferase
complex
C
IDA
SceS000005770
GO:0033100 NuA3 histone acetyltransferase
complex
C
IDA
SceS000000148
GO:0033255 SAS acetyltransferase complex C
IDA
SceS000004734
IPI
SceS000004734
GO:0035267 NuA4 histone acetyltransferase
complex
C
IDA
SpoSPAC637.12c
IPI
SceS000005770
GO:0071339 MLL1 complex C
IDA
HsaMYST1
GO:0003676 nucleic acid binding F
ISS
AthAt5g64610
At5g09740
GO:0003682 chromatin binding F
IDA
DmeFBgn0014340
TAS
DmeFBgn0014340
GO:0003729 mRNA binding F
TAS
DmeFBgn0014340
GO:0004402 histone acetyltransferase activity F
IDA
AthAt5g09740
At5g64610
HsaMYST1
SceS000000148
S000004734
IMP
SceS000000148
S000005770
ISS
AthAt5g09740
At5g64610
DmeFBgn0014340
NAS
DmeFBgn0014340
SpoSPAC17G8.13c
RCA
SceS000005770
TAS
DmeFBgn0014340
GO:0004468 lysine N-acetyltransferase activity F
TAS
DmeFBgn0014340
GO:0005515 protein binding F
IPI
HsaMYST1
MYST2
SpoSPAC637.12c
TAS
DmeFBgn0014340
GO:0008134 transcription factor binding F
IDA
HsaMYST1
GO:0008270 zinc ion binding F
ISS
AthAt5g09740
At5g64610
GO:0010485 H4 histone acetyltransferase activity F
IDA
SceS000005770
ISS
SpoSPAC637.12c
GO:0016407 acetyltransferase activity F
IDA
HsaMYST1
SceS000004734
GO:0046972 histone acetyltransferase activity (H4-K16
specific)
F
TAS
DmeFBgn0014340
GO:0000003 reproduction P
IMP
CelWBGene00007029
GO:0000183 chromatin silencing at rDNA P
IGI
SceS000005770
IMP
SceS000005770
GO:0002009 morphogenesis of an epithelium P
IMP
CelWBGene00007029
GO:0002119 nematode larval development P
IMP
CelWBGene00007029
GO:0006260 DNA replication P
IDA
HsaMYST2
GO:0006281 DNA repair P
IDA
SceS000005770
IMP
SceS000005770
GO:0006302 double-strand break repair P
IGI
SpoSPAC637.12c
GO:0006338 chromatin remodeling P
NAS
SpoSPAC637.12c
GO:0006348 chromatin silencing at telomere P
IDA
SceS000004734
IMP
SceS000000148
RCA
SceS000005770
GO:0006354 RNA elongation P
IDA
SceS000005770
IMP
SceS000005770
GO:0006357 regulation of transcription from RNA polymerase II
promoter
P
IMP
SceS000005770
GO:0006898 receptor-mediated endocytosis P
IMP
CelWBGene00007029
GO:0007059 chromosome segregation P
IMP
SpoSPAC637.12c
GO:0007549 dosage compensation P
IGI
DmeFBgn0014340
IMP
DmeFBgn0014340
NAS
DmeFBgn0014340
TAS
DmeFBgn0014340
GO:0009047 dosage compensation, by hyperactivation of X
chromosome
P
NAS
DmeFBgn0014340
GO:0009792 embryo development ending in birth or egg
hatching
P
IMP
CelWBGene00007029
GO:0010171 body morphogenesis P
IMP
CelWBGene00007029
GO:0016481 negative regulation of transcription P
IDA
HsaMYST1
GO:0016568 chromatin modification P
IMP
SceS000000148
GO:0016573 histone acetylation P
IDA
HsaMYST1
SceS000000148
S000005770
IMP
SceS000004734
S000000148
NAS
DmeFBgn0014340
TAS
DmeFBgn0014340
SpoSPAC17G8.13c
GO:0018394 peptidyl-lysine acetylation P
TAS
DmeFBgn0014340
GO:0030099 myeloid cell differentiation P
IDA
HsaMYST1
GO:0030466 chromatin silencing at silent mating-type
cassette
P
IMP
SceS000000148
GO:0031939 negative regulation of chromatin silencing at
telomere
P
IGI
SpoSPAC17G8.13c
IMP
SpoSPAC17G8.13c
GO:0032968 positive regulation of RNA elongation from RNA
polymerase II promoter
P
IGI
SceS000005770
IMP
SceS000005770
GO:0034401 regulation of transcription by chromatin
organization
P
IMP
SceS000005770
GO:0034508 centromere complex assembly P
IGI
SpoSPAC637.12c
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00007029
GO:0040027 negative regulation of vulval development P
IMP
CelWBGene00007029
GO:0043486 histone exchange P
IMP
SceS000004734
GO:0043966 histone H3 acetylation P
IDA
HsaMYST2
GO:0043967 histone H4 acetylation P
ISS
SpoSPAC637.12c
GO:0043981 histone H4-K5 acetylation P
IDA
HsaMYST2
GO:0043982 histone H4-K8 acetylation P
IDA
HsaMYST2
GO:0043983 histone H4-K12 acetylation P
IDA
HsaMYST2
GO:0043984 histone H4-K16 acetylation P
IMP
HsaMYST1
GO:0045893 positive regulation of transcription,
DNA-dependent
P
IMP
HsaMYST1
GO:0045941 positive regulation of transcription P
IDA
HsaMYST1
GO:0048478 replication fork protection P
IGI
SpoSPAC637.12c
GO:0051445 regulation of meiotic cell cycle P
IMP
SpoSPAC17G8.13c
GO:0051726 regulation of cell cycle P
IMP
SceS000005770

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
100661

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) KAT5 GI:36287069
Pan troglodytes (Ptr) KAT5 GI:114638602
Canis familiaris (Cfa) KAT5 GI:73983068
Mus musculus (Mmu) Kat5
(MGI:1932051)
GI:30519991 A2VDH4
Rattus norvegicus (Rno) Kat5 GI:54607159
Drosophila melanogaster (Dme) Tip60
(FBgn0026080)
GI:18858193
Anopheles gambiae (Aga) AgaP_AGAP001539 GI:158301907
Caenorhabditis elegans (Cel) mys-1
(CE21225;
WBGene00007029)
GI:17564938 Q9TYU5
Schizosaccharomyces pombe (Spo) mst1
(SPAC637.12c)
GI:19115542 O94446
Saccharomyces cerevisiae (Sce) ESA1
(S000005770)
GI:6324818 Q08649
Kluyveromyces lactis (Kla) KLLA0F11209g GI:50311133
Eremothecium gossypii (Ego) AGOS_ACR138W GI:45185824
Magnaporthe grisea (Mgr) MGG_04133 GI:39944244
Neurospora crassa (Ncr) NCU05218.1 GI:32408187