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Search term: YOR245C

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name DGA1
SGD link S000005771
Alternative ID YOR245C
Description Diacylglycerol acyltransferase, catalyzes the terminal step of triacylglycerol (TAG) formation, acylates diacylglycerol using acyl-CoA as an acyl donor, localized to lipid particles
Synonyms YOR245C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG0831 ACDHYP-

KOGs classification KOGs description
METABOLISM Acyl-CoA:diacylglycerol acyltransferase (DGAT)

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At3g51520 GI:11281663
Caenorhabditis elegans (Cel) CE14392
(WBGene00020910)		 GI:17564946 Q23067
Caenorhabditis elegans (Cel) CE18794
(WBGene00010296)		 GI:17561696 Q9XUW0
Caenorhabditis elegans (Cel) CE25428
(WBGene00021818)		 GI:17556144 Q9N4S3
Caenorhabditis elegans (Cel) CE27391
(WBGene00019464)		 GI:17562274 O01881
Drosophila melanogaster (Dme) 7304164 GI:7304164
Drosophila melanogaster (Dme) 7304165
(FBgn0033215)		 GI:19921764
Drosophila melanogaster (Dme) 7304166
(FBgn0033214)		 GI:19921762
Homo sapiens (Hsa) Hs18595884 GI:18595884
Homo sapiens (Hsa) Hs18595888 GI:18595888
Homo sapiens (Hsa) Hs22058366 GI:22058366
Homo sapiens (Hsa) Hs13376662 GI:13376662
Homo sapiens (Hsa) Hs14211871 GI:14211871
Homo sapiens (Hsa) Hs17157995 GI:17157995
Saccharomyces cerevisiae (Sce) YOR245c
(S000005771)		 GI:6324819 Q08650
Schizosaccharomyces pombe (Spo) SPCC1235.15 GI:19075241 O74850
Schizosaccharomyces pombe (Spo) SPCC548.01 GI:19075242
Arabidopsis thaliana (Ath) At3g51520 GI:11281663
Caenorhabditis elegans (Cel) CE14392
(WBGene00020910)		 GI:17564946 Q23067
Caenorhabditis elegans (Cel) CE18794
(WBGene00010296)		 GI:17561696 Q9XUW0
Caenorhabditis elegans (Cel) CE25428
(WBGene00021818)		 GI:17556144 Q9N4S3
Caenorhabditis elegans (Cel) CE27391
(WBGene00019464)		 GI:17562274 O01881
Drosophila melanogaster (Dme) 7304164 GI:7304164
Drosophila melanogaster (Dme) 7304165
(FBgn0033215)		 GI:19921764
Drosophila melanogaster (Dme) 7304166
(FBgn0033214)		 GI:19921762
Homo sapiens (Hsa) Hs18595884 GI:18595884
Homo sapiens (Hsa) Hs18595888 GI:18595888
Homo sapiens (Hsa) Hs22058366 GI:22058366
Homo sapiens (Hsa) Hs13376662 GI:13376662
Homo sapiens (Hsa) Hs14211871 GI:14211871
Homo sapiens (Hsa) Hs17157995 GI:17157995
Saccharomyces cerevisiae (Sce) YOR245c
(S000005771)		 GI:6324819 Q08650
Schizosaccharomyces pombe (Spo) SPCC1235.15 GI:19075241 O74850
Schizosaccharomyces pombe (Spo) SPCC548.01 GI:19075242


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
AthAt3g51520
GO:0005737 cytoplasm C
IDA
SpoSPCC1235.15
GO:0005783 endoplasmic reticulum C
IDA
SpoSPCC1235.15
GO:0005811 lipid particle C
IDA
SceS000005771
GO:0004144 diacylglycerol O-acyltransferase
activity		 F
IDA
SceS000005771
SpoSPCC1235.15
IMP
SceS000005771
ISS
AthAt3g51520
GO:0006914 autophagy P
RCA
SceS000005771
GO:0007498 mesoderm development P
NAS
DmeFBgn0033215
GO:0008150 biological_process P
ND
AthAt3g51520
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00020910
GO:0019432 triglyceride biosynthetic process P
IDA
SceS000005771
SpoSPCC1235.15
IMP
SceS000005771
GO:0019915 lipid storage P
IC
SpoSPCC1235.15
IMP
SceS000005771
GO:0046339 diacylglycerol metabolic process P
IC
SpoSPCC1235.15

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
105237

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) MOGAT1 GI:148746191
Pan troglodytes (Ptr) MOGAT1 GI:114583596
Canis familiaris (Cfa) MOGAT1 GI:74005805
Mus musculus (Mmu) Mogat1
(MGI:1915643)		 GI:18426805 Q3V4B0
Rattus norvegicus (Rno) Mogat1 GI:109486272
Caenorhabditis elegans (Cel) K07B1.4
(CE27391;
WBGene00019464)		 GI:17562274 O01881
Caenorhabditis elegans (Cel) Y53G8B.2
(CE25428;
WBGene00021818)		 GI:17556144 Q9N4S3
Caenorhabditis elegans (Cel) F59A1.10
(CE18794;
WBGene00010296)		 GI:17561696 Q9XUW0
Caenorhabditis elegans (Cel) W01A11.2
(CE14392;
WBGene00020910)		 GI:17564946 Q23067
Schizosaccharomyces pombe (Spo) SPCC1235.15z GI:63054410
Saccharomyces cerevisiae (Sce) DGA1
(S000005771)		 GI:6324819 Q08650
Kluyveromyces lactis (Kla) KLLA0F11165g GI:50311129
Eremothecium gossypii (Ego) AGOS_ACR140C GI:45185826
Magnaporthe grisea (Mgr) MGG_00503 GI:39974701
Neurospora crassa (Ncr) NCU02665.1 GI:32422841


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005624 membrane fraction C
IDA
MmuMGI:1915643
GO:0005783 endoplasmic reticulum C
IDA
MmuMGI:1915643
GO:0005811 lipid particle C
IDA
SceS000005771
GO:0003846 2-acylglycerol O-acyltransferase
activity		 F
IDA
MmuMGI:1915643
GO:0004144 diacylglycerol O-acyltransferase
activity		 F
IDA
MmuMGI:1915643
SceS000005771
IMP
SceS000005771
GO:0006651 diacylglycerol biosynthetic process P
IDA
MmuMGI:1915643
GO:0006914 autophagy P
RCA
SceS000005771
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00020910
GO:0019432 triglyceride biosynthetic process P
IDA
SceS000005771
IMP
SceS000005771
GO:0019915 lipid storage P
IMP
SceS000005771

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_349

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga1395 ENSANGP00000010804
Anopheles gambiae (Aga) aga1394 ENSANGP00000024789
Ashbya gossypii (Ago) ago1187 ACR140C
Arabidopsis thaliana (Ath) ath16471 At3g51520.1
Caenorhabditis elegans (Cel) cel10988 F59A1.10
(CE18794;
WBGene00010296)
Caenorhabditis elegans (Cel) cel12090 K07B1.4a
(CE27391;
WBGene00019464)
Caenorhabditis elegans (Cel) cel12091 K07B1.4b
(CE11882)
Caenorhabditis elegans (Cel) cel16711 W01A11.2
(CE14392;
WBGene00020910)
Caenorhabditis elegans (Cel) cel19668 Y53G8B.2
(CE25428;
WBGene00021818)
Candida glabrata (Cgl) cgl3147 CAGL0J03674g
Cryptococcus neoformans (Cne) cne1103 180.m00027
Cryptococcus neoformans (Cne) cne1104 180.m00028
Cryptococcus neoformans (Cne) cne1105 180.m00029
Dictyostelium discoideum (Ddi) ddi7518 DDB0188804
Debaryomyces hansenii (Dha) dha2008 DEHA0C13101g
Drosophila melanogaster (Dme) dme3716 CG1941-PA
(FBgn0033214)
Drosophila melanogaster (Dme) dme3717 CG1942-PA
(FBgn0033215)
Drosophila melanogaster (Dme) dme3718 CG1946-PA
(FBgn0033216)
Danio rerio (Dre) dre27609 ENSDARP00000009175
(zgc:101667)		 Q5XJR1
Danio rerio (Dre) dre19487 ENSDARP00000019176
(LOC565116)
Danio rerio (Dre) dre10560 ENSDARP00000022154
Takifugu rubripes (Fru) fru3079 SINFRUP00000132701
Takifugu rubripes (Fru) fru3080 SINFRUP00000132704
Takifugu rubripes (Fru) fru8907 SINFRUP00000133787
Takifugu rubripes (Fru) fru23514 SINFRUP00000134972
Takifugu rubripes (Fru) fru2810 SINFRUP00000141951
Gallus gallus (Gga) gga16652 ENSGALP00000006955
Gallus gallus (Gga) gga16651 ENSGALP00000006956
(LOC428693)
Gallus gallus (Gga) gga23239 ENSGALP00000008369
Gallus gallus (Gga) gga14522 ENSGALP00000014824
(DGAT2)
Gallus gallus (Gga) gga27058 ENSGALP00000022878
(MOGAT2)
Homo sapiens (Hsa) hsa6255 ENSP00000198801
(MOGAT2)		 Q3SYC2-1
Homo sapiens (Hsa) hsa6256 ENSP00000228027
(DGAT2)		 Q96PD7-1
Homo sapiens (Hsa) hsa19363 ENSP00000264412
(MOGAT1)		 Q96PD6
Kluyveromyces lactis (Kla) kla4588 KLLA0F11165g
Mus musculus (Mmu) mmu618 ENSMUSP00000012331
(MGI:1915643)		 Q91ZV4
Mus musculus (Mmu) mmu24486 ENSMUSP00000033001
(MGI:1915050)		 Q9DCV3
Mus musculus (Mmu) mmu24487 ENSMUSP00000064041
(MGI:2663253)		 Q80W94
Mus musculus (Mmu) mmu29347 ENSMUSP00000078702
Neurospora crassa (Ncr) ncr2581 NCU02665.2
Oryza sativa (Osa) osa7867 2528.m00240
Oryza sativa (Osa) osa24096 3788.m00205
Oryza sativa (Osa) osa38982 5079.m00071
Rattus norvegicus (Rno) rno30310 ENSRNOP00000019724
(RGD:1311644)
Rattus norvegicus (Rno) rno2381 ENSRNOP00000022557
(RGD:620329)		 Q5FVP8
Rattus norvegicus (Rno) rno2382 ENSRNOP00000036315
(RGD:1598060)		 B2RZ21
Rattus norvegicus (Rno) rno31641 ENSRNOP00000039497
Rattus norvegicus (Rno) rno8342 ENSRNOP00000039507
(RGD:1308425)
Rattus norvegicus (Rno) rno30306 ENSRNOP00000040629
Rattus norvegicus (Rno) rno30305 ENSRNOP00000041736
Rattus norvegicus (Rno) rno8343 ENSRNOP00000042554
Rattus norvegicus (Rno) rno8345 ENSRNOP00000044746
Rattus norvegicus (Rno) rno30309 ENSRNOP00000045694
Rattus norvegicus (Rno) rno8344 ENSRNOP00000046989
(GI:685560)
Rattus norvegicus (Rno) rno8346 ENSRNOP00000047903
Rattus norvegicus (Rno) rno30307 ENSRNOP00000049845
Rattus norvegicus (Rno) rno8341 ENSRNOP00000051273
Saccharomyces cerevisiae (Sce) sce5991 YOR245C
(S000005771)
Schizosaccharomyces pombe (Spo) spo3311 SPCC1235.15 O74850
Yarrowia lipolytica (Yli) yli5227 YALI0E32769g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
AthAt3g51520
GO:0005624 membrane fraction C
IDA
MmuMGI:1915643
MGI:1915050
GO:0005737 cytoplasm C
IDA
SpoSPCC1235.15
GO:0005783 endoplasmic reticulum C
IDA
MmuMGI:1915643
SpoSPCC1235.15
ISA
MmuMGI:2663253
GO:0005792 microsome C
ISO
MmuMGI:1915050
GO:0005811 lipid particle C
IDA
SceS000005771
GO:0016021 integral to membrane C
IDA
MmuMGI:1915050
GO:0003846 2-acylglycerol O-acyltransferase
activity		 F
IDA
MmuMGI:1915643
MGI:1915050
MGI:2663253
ISA
MmuMGI:2663253
GO:0004144 diacylglycerol O-acyltransferase
activity		 F
IDA
MmuMGI:1915643
MGI:1915050
SceS000005771
SpoSPCC1235.15
IMP
SceS000005771
ISO
MmuMGI:1915050
ISS
AthAt3g51520
GO:0016407 acetyltransferase activity F
IDA
MmuMGI:2663253
GO:0006629 lipid metabolic process P
IDA
MmuMGI:2663253
GO:0006651 diacylglycerol biosynthetic process P
IDA
MmuMGI:1915643
MGI:2663253
GO:0006914 autophagy P
RCA
SceS000005771
GO:0007498 mesoderm development P
NAS
DmeFBgn0033215
GO:0008150 biological_process P
ND
AthAt3g51520
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00020910
GO:0019432 triglyceride biosynthetic process P
IDA
MmuMGI:2663253
MGI:1915050
SceS000005771
SpoSPCC1235.15
IMP
MmuMGI:1915050
SceS000005771
GO:0019915 lipid storage P
IC
SpoSPCC1235.15
IMP
SceS000005771
GO:0046339 diacylglycerol metabolic process P
IC
SpoSPCC1235.15
GO:0046462 monoacylglycerol metabolic process P
ISA
MmuMGI:2663253
GO:0050892 intestinal absorption P
IDA
MmuMGI:2663253

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPCC1235.15
(O74850)		 YOR245C
(S000005771)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005737 cytoplasm C
IDA
SpoSPCC1235.15
GO:0005783 endoplasmic reticulum C
IDA
SpoSPCC1235.15
GO:0005811 lipid particle C
IDA
SceS000005771
GO:0004144 diacylglycerol O-acyltransferase
activity		 F
IDA
SceS000005771
SpoSPCC1235.15
IMP
SceS000005771
GO:0006914 autophagy P
RCA
SceS000005771
GO:0019432 triglyceride biosynthetic process P
IDA
SceS000005771
SpoSPCC1235.15
IMP
SceS000005771
GO:0019915 lipid storage P
IC
SpoSPCC1235.15
IMP
SceS000005771
GO:0046339 diacylglycerol metabolic process P
IC
SpoSPCC1235.15

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