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Search term: YOR261C

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name RPN8
SGD link S000005787
Alternative ID YOR261C
Description Essential, non-ATPase regulatory subunit of the 26S proteasome; has similarity to the human p40 proteasomal subunit and to another S. cerevisiae regulatory subunit, Rpn11p
Synonyms YOR261C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG1556 ACDHYPE

KOGs classification KOGs description
CELLULAR PROCESSES AND SIGNALING 26S proteasome regulatory complex, subunit RPN8/PSMD7

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At3g11270 GI:15229710
Arabidopsis thaliana (Ath) At5g05780 GI:15239230
Caenorhabditis elegans (Cel) CE18135
(WBGene00004464)		 GI:17508685 O61792
Drosophila melanogaster (Dme) 7291779 GI:7291779
Homo sapiens (Hsa) Hs4506231 GI:4506231
Saccharomyces cerevisiae (Sce) YOR261c
(S000005787)		 GI:6324835 Q08723
Schizosaccharomyces pombe (Spo) SPCC1682.10 GI:19075303 O74440
Encephalitozoon cuniculi (Ecu) ECU04g0420 GI:19074119 Q8SS61


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SpoSPCC1682.10
TAS
AthAt3g11270
SpoSPCC1682.10
GO:0005635 nuclear envelope C
IDA
SpoSPCC1682.10
GO:0005829 cytosol C
IDA
SpoSPCC1682.10
GO:0008541 proteasome regulatory particle, lid
subcomplex		 C
IDA
SceS000005787
ISS
AthAt5g05780
At3g11270
SpoSPCC1682.10
GO:0034515 proteasome storage granule C
IDA
SceS000005787
GO:0003674 molecular_function F
ND
AthAt5g05780
At3g11270
SceS000005787
SpoSPCC1682.10
GO:0004175 endopeptidase activity F
RCA
SceS000005787
GO:0008233 peptidase activity F
RCA
SceS000005787
GO:0070011 peptidase activity, acting on L-amino acid
peptides		 F
RCA
SceS000005787
GO:0000003 reproduction P
IMP
CelWBGene00004464
GO:0000278 mitotic cell cycle P
IC
SpoSPCC1682.10
GO:0002119 nematode larval development P
IMP
CelWBGene00004464
GO:0006508 proteolysis P
RCA
SceS000005787
GO:0006511 ubiquitin-dependent protein catabolic
process		 P
ISS
SpoSPCC1682.10
TAS
AthAt5g05780
At3g11270
SceS000005787
GO:0007346 regulation of mitotic cell cycle P
NAS
SpoSPCC1682.10
GO:0008340 determination of adult lifespan P
IMP
CelWBGene00004464
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00004464
GO:0009793 embryo development ending in seed
dormancy		 P
IMP
AthAt3g11270
GO:0009965 leaf morphogenesis P
IMP
AthAt5g05780
GO:0030163 protein catabolic process P
TAS
AthAt3g11270
GO:0040007 growth P
IMP
CelWBGene00004464
GO:0043161 proteasomal ubiquitin-dependent protein catabolic
process		 P
NAS
SpoSPCC1682.10

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
2104

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) PSMD7 GI:25777615
Pan troglodytes (Ptr) PSMD7 GI:114663620
Canis familiaris (Cfa) PSMD7 GI:57087181
Mus musculus (Mmu) Psmd7
(MGI:1351511)		 GI:6754724 A1L3B8
Rattus norvegicus (Rno) Psmd7 GI:109508092
Gallus gallus (Gga) PSMD7 GI:118096637
Drosophila melanogaster (Dme) Mov34
(FBgn0002787)		 GI:24762618
Anopheles gambiae (Aga) AgaP_AGAP012135 GI:158300491
Caenorhabditis elegans (Cel) rpn-8
(CE18135;
WBGene00004464)		 GI:17508685 O61792
Schizosaccharomyces pombe (Spo) rpn8
(SPCC1682.10)		 GI:19075303 O74440
Saccharomyces cerevisiae (Sce) RPN8
(S000005787)		 GI:6324835 Q08723
Kluyveromyces lactis (Kla) KLLA0C09526g GI:50305325
Eremothecium gossypii (Ego) AGOS_AAL116W GI:45184708
Magnaporthe grisea (Mgr) MGG_01059 GI:39973589
Neurospora crassa (Ncr) NCU01547.1 GI:32415013
Arabidopsis thaliana (Ath) MEE34 GI:15229710
Arabidopsis thaliana (Ath) RPN8A GI:15239230
Oryza sativa (Osa) Os04g0661900 GI:115461104
Plasmodium falciparum (Pfa) PFI0630w GI:124506807


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000502 proteasome complex C
IDA
DmeFBgn0002787
NAS
DmeFBgn0002787
GO:0005634 nucleus C
IDA
SpoSPCC1682.10
TAS
AthMEE34
SpoSPCC1682.10
GO:0005635 nuclear envelope C
IDA
SpoSPCC1682.10
GO:0005829 cytosol C
IDA
SpoSPCC1682.10
GO:0005838 proteasome regulatory particle C
IDA
DmeFBgn0002787
ISS
DmeFBgn0002787
TAS
HsaPSMD7
GO:0008541 proteasome regulatory particle, lid
subcomplex		 C
IDA
SceS000005787
ISS
AthRPN8A
MEE34
DmeFBgn0002787
SpoSPCC1682.10
NAS
DmeFBgn0002787
GO:0030425 dendrite C
IMP
DmeFBgn0002787
GO:0034515 proteasome storage granule C
IDA
SceS000005787
GO:0003674 molecular_function F
ND
AthRPN8A
MEE34
SceS000005787
SpoSPCC1682.10
GO:0004175 endopeptidase activity F
IDA
DmeFBgn0002787
NAS
DmeFBgn0002787
RCA
SceS000005787
GO:0005515 protein binding F
IPI
HsaPSMD7
GO:0008233 peptidase activity F
RCA
SceS000005787
GO:0070011 peptidase activity, acting on L-amino acid
peptides		 F
RCA
SceS000005787
GO:0000003 reproduction P
IMP
CelWBGene00004464
GO:0000022 mitotic spindle elongation P
IMP
DmeFBgn0002787
GO:0000278 mitotic cell cycle P
IC
SpoSPCC1682.10
GO:0002119 nematode larval development P
IMP
CelWBGene00004464
GO:0006508 proteolysis P
IDA
DmeFBgn0002787
ISS
DmeFBgn0002787
RCA
SceS000005787
GO:0006511 ubiquitin-dependent protein catabolic
process		 P
ISS
SpoSPCC1682.10
NAS
DmeFBgn0002787
TAS
AthMEE34
RPN8A
SceS000005787
GO:0007052 mitotic spindle organization P
IMP
DmeFBgn0002787
GO:0007346 regulation of mitotic cell cycle P
NAS
SpoSPCC1682.10
GO:0008283 cell proliferation P
IMP
DmeFBgn0002787
GO:0008340 determination of adult lifespan P
IMP
CelWBGene00004464
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00004464
GO:0009793 embryo development ending in seed
dormancy		 P
IMP
AthMEE34
GO:0009965 leaf morphogenesis P
IMP
AthRPN8A
GO:0009987 cellular process P
IMP
DmeFBgn0002787
GO:0030163 protein catabolic process P
TAS
AthMEE34
GO:0031145 anaphase-promoting complex-dependent proteasomal
ubiquitin-dependent protein catabolic
process		 P
EXP
HsaPSMD7
GO:0040007 growth P
IMP
CelWBGene00004464
GO:0043161 proteasomal ubiquitin-dependent protein catabolic
process		 P
NAS
SpoSPCC1682.10
GO:0051436 negative regulation of ubiquitin-protein ligase
activity involved in mitotic cell
cycle		 P
EXP
HsaPSMD7
GO:0051437 positive regulation of ubiquitin-protein ligase
activity involved in mitotic cell
cycle		 P
EXP
HsaPSMD7

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_2226

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga9325 ENSANGP00000013949
Ashbya gossypii (Ago) ago71 AAL116W
Arabidopsis thaliana (Ath) ath13237 At3g11270.1
Arabidopsis thaliana (Ath) ath22764 At5g05780.1
Caenorhabditis elegans (Cel) cel13931 R12E2.3
(CE18135;
WBGene00004464)
Candida glabrata (Cgl) cgl3903 CAGL0K08866g
Cryptococcus neoformans (Cne) cne1856 181.m07820
Dictyostelium discoideum (Ddi) ddi5771 DDB0205949
Debaryomyces hansenii (Dha) dha5268 DEHA0F19866g
Drosophila melanogaster (Dme) dme6996 CG3416-PA
(FBgn0002787)
Danio rerio (Dre) dre1140 ENSDARP00000016908
Encephalitozoon cuniculi (Ecu) ecu757 19074119
Takifugu rubripes (Fru) fru10421 SINFRUP00000136251
Takifugu rubripes (Fru) fru10422 SINFRUP00000171611
Gallus gallus (Gga) gga4882 ENSGALP00000000999
(PSMD7)		 Q5ZL99
Homo sapiens (Hsa) hsa12500 ENSP00000219313
(PSMD7)		 P51665
Kluyveromyces lactis (Kla) kla1621 KLLA0C09526g
Mus musculus (Mmu) mmu26662 ENSMUSP00000041968
(MGI:1351511)		 P26516
Neurospora crassa (Ncr) ncr1502 NCU01547.2
Oryza sativa (Osa) osa81196 8213.m00150
Plasmodium falciparum (Pfa) pfa4593 PFI0630w
Rattus norvegicus (Rno) rno14968 ENSRNOP00000019104
(RGD:1306902)
Saccharomyces cerevisiae (Sce) sce6007 YOR261C
(S000005787)
Schizosaccharomyces pombe (Spo) spo2959 SPCC1682.10 O74440
Yarrowia lipolytica (Yli) yli3537 YALI0D19910g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000502 proteasome complex C
IDA
DmeFBgn0002787
NAS
DmeFBgn0002787
GO:0005634 nucleus C
IDA
SpoSPCC1682.10
TAS
AthAt3g11270
SpoSPCC1682.10
GO:0005635 nuclear envelope C
IDA
SpoSPCC1682.10
GO:0005829 cytosol C
IDA
SpoSPCC1682.10
GO:0005838 proteasome regulatory particle C
IDA
DmeFBgn0002787
ISS
DmeFBgn0002787
GO:0008541 proteasome regulatory particle, lid
subcomplex		 C
IDA
SceS000005787
ISS
AthAt5g05780
At3g11270
DmeFBgn0002787
SpoSPCC1682.10
NAS
DmeFBgn0002787
GO:0030425 dendrite C
IMP
DmeFBgn0002787
GO:0034515 proteasome storage granule C
IDA
SceS000005787
GO:0003674 molecular_function F
ND
AthAt5g05780
At3g11270
SceS000005787
SpoSPCC1682.10
GO:0004175 endopeptidase activity F
IDA
DmeFBgn0002787
NAS
DmeFBgn0002787
RCA
SceS000005787
GO:0008233 peptidase activity F
RCA
SceS000005787
GO:0070011 peptidase activity, acting on L-amino acid
peptides		 F
RCA
SceS000005787
GO:0000003 reproduction P
IMP
CelWBGene00004464
GO:0000022 mitotic spindle elongation P
IMP
DmeFBgn0002787
GO:0000278 mitotic cell cycle P
IC
SpoSPCC1682.10
GO:0002119 nematode larval development P
IMP
CelWBGene00004464
GO:0006508 proteolysis P
IDA
DmeFBgn0002787
ISS
DmeFBgn0002787
RCA
SceS000005787
GO:0006511 ubiquitin-dependent protein catabolic
process		 P
ISS
SpoSPCC1682.10
NAS
DmeFBgn0002787
TAS
AthAt5g05780
At3g11270
SceS000005787
GO:0007052 mitotic spindle organization P
IMP
DmeFBgn0002787
GO:0007346 regulation of mitotic cell cycle P
NAS
SpoSPCC1682.10
GO:0008283 cell proliferation P
IMP
DmeFBgn0002787
GO:0008340 determination of adult lifespan P
IMP
CelWBGene00004464
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00004464
GO:0009793 embryo development ending in seed
dormancy		 P
IMP
AthAt3g11270
GO:0009965 leaf morphogenesis P
IMP
AthAt5g05780
GO:0009987 cellular process P
IMP
DmeFBgn0002787
GO:0030163 protein catabolic process P
TAS
AthAt3g11270
GO:0040007 growth P
IMP
CelWBGene00004464
GO:0043161 proteasomal ubiquitin-dependent protein catabolic
process		 P
NAS
SpoSPCC1682.10

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPCC1682.10
(O74440)		 YOR261C
(S000005787)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SpoSPCC1682.10
TAS
SpoSPCC1682.10
GO:0005635 nuclear envelope C
IDA
SpoSPCC1682.10
GO:0005829 cytosol C
IDA
SpoSPCC1682.10
GO:0008541 proteasome regulatory particle, lid
subcomplex		 C
IDA
SceS000005787
ISS
SpoSPCC1682.10
GO:0034515 proteasome storage granule C
IDA
SceS000005787
GO:0003674 molecular_function F
ND
SceS000005787
SpoSPCC1682.10
GO:0004175 endopeptidase activity F
RCA
SceS000005787
GO:0008233 peptidase activity F
RCA
SceS000005787
GO:0070011 peptidase activity, acting on L-amino acid
peptides		 F
RCA
SceS000005787
GO:0000278 mitotic cell cycle P
IC
SpoSPCC1682.10
GO:0006508 proteolysis P
RCA
SceS000005787
GO:0006511 ubiquitin-dependent protein catabolic
process		 P
ISS
SpoSPCC1682.10
TAS
SceS000005787
GO:0007346 regulation of mitotic cell cycle P
NAS
SpoSPCC1682.10
GO:0043161 proteasomal ubiquitin-dependent protein catabolic
process		 P
NAS
SpoSPCC1682.10

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