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Search term: YOR291W

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name YPK9
SGD link S000005817
Alternative ID YOR291W
Description Vacuolar protein with a possible role in sequestering heavy metals; has similarity to the type V P-type ATPase Spf1p; homolog of human ATP13A2 (PARK9), mutations in which are associated with Parkinson disease and Kufor?Rakeb syndrome
Synonyms YOR291W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG0208 -C-HYPE

KOGs classification KOGs description
METABOLISM Cation transport ATPase

Species KOG link NCBI link UniProt link
Caenorhabditis elegans (Cel) CE06560 GI:17542822
Caenorhabditis elegans (Cel) CE21026 GI:17568741
Caenorhabditis elegans (Cel) CE29128 GI:17543844
Homo sapiens (Hsa) Hs13435129
(ATP13A2)		 GI:13435129 Q9NQ11
Homo sapiens (Hsa) Hs14728742 GI:14728742
Homo sapiens (Hsa) Hs20536134 GI:20536134
Homo sapiens (Hsa) Hs21362056 GI:16516658 Q9H7F0
Homo sapiens (Hsa) HsM13375668 GI:13375668
Saccharomyces cerevisiae (Sce) YOR291w
(S000005817)		 GI:6324865 Q12697
Schizosaccharomyces pombe (Spo) SPAC29A4.19c GI:19115775 O14022
Schizosaccharomyces pombe (Spo) SPCC1672.11c GI:19075382 O74431
Encephalitozoon cuniculi (Ecu) ECU07g1500 GI:19074572 Q8SRH4
Caenorhabditis elegans (Cel) CE06560 GI:17542822
Caenorhabditis elegans (Cel) CE21026 GI:17568741
Caenorhabditis elegans (Cel) CE29128 GI:17543844
Homo sapiens (Hsa) Hs13435129
(ATP13A2)		 GI:13435129 Q9NQ11
Homo sapiens (Hsa) Hs14728742 GI:14728742
Homo sapiens (Hsa) Hs20536134 GI:20536134
Homo sapiens (Hsa) Hs21362056 GI:16516658 Q9H7F0
Homo sapiens (Hsa) HsM13375668 GI:13375668
Saccharomyces cerevisiae (Sce) YOR291w
(S000005817)		 GI:6324865 Q12697
Schizosaccharomyces pombe (Spo) SPAC29A4.19c GI:19115775 O14022
Schizosaccharomyces pombe (Spo) SPCC1672.11c GI:19075382 O74431
Encephalitozoon cuniculi (Ecu) ECU07g1500 GI:19074572 Q8SRH4
Caenorhabditis elegans (Cel) CE06560 GI:17542822
Caenorhabditis elegans (Cel) CE21026 GI:17568741
Caenorhabditis elegans (Cel) CE29128 GI:17543844
Homo sapiens (Hsa) Hs13435129
(ATP13A2)		 GI:13435129 Q9NQ11
Homo sapiens (Hsa) Hs14728742 GI:14728742
Homo sapiens (Hsa) Hs20536134 GI:20536134
Homo sapiens (Hsa) Hs21362056 GI:16516658 Q9H7F0
Homo sapiens (Hsa) HsM13375668 GI:13375668
Saccharomyces cerevisiae (Sce) YOR291w
(S000005817)		 GI:6324865 Q12697
Schizosaccharomyces pombe (Spo) SPAC29A4.19c GI:19115775 O14022
Schizosaccharomyces pombe (Spo) SPCC1672.11c GI:19075382 O74431
Encephalitozoon cuniculi (Ecu) ECU07g1500 GI:19074572 Q8SRH4


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000329 fungal-type vacuole membrane C
IDA
SceS000005817
GO:0005783 endoplasmic reticulum C
IDA
SpoSPCC1672.11c
SPAC29A4.19c
GO:0005794 Golgi apparatus C
IDA
SpoSPAC29A4.19c
GO:0003674 molecular_function F
ND
SceS000005817
GO:0005388 calcium-transporting ATPase activity F
IGI
SpoSPAC29A4.19c
GO:0015075 ion transmembrane transporter activity F
RCA
SceS000005817
GO:0015399 primary active transmembrane transporter
activity		 F
RCA
SceS000005817
GO:0015405 P-P-bond-hydrolysis-driven transmembrane
transporter activity		 F
RCA
SceS000005817
GO:0015662 ATPase activity, coupled to transmembrane movement
of ions, phosphorylative mechanism		 F
RCA
SceS000005817
GO:0016820 hydrolase activity, acting on acid anhydrides,
catalyzing transmembrane movement of
substances		 F
RCA
SceS000005817
GO:0016887 ATPase activity F
RCA
SceS000005817
GO:0022804 active transmembrane transporter
activity		 F
RCA
SceS000005817
GO:0022857 transmembrane transporter activity F
RCA
SceS000005817
GO:0022891 substrate-specific transmembrane transporter
activity		 F
RCA
SceS000005817
GO:0042623 ATPase activity, coupled F
RCA
SceS000005817
GO:0042625 ATPase activity, coupled to transmembrane movement
of ions		 F
RCA
SceS000005817
GO:0042626 ATPase activity, coupled to transmembrane movement
of substances		 F
ISS
SpoSPCC1672.11c
RCA
SceS000005817
GO:0043492 ATPase activity, coupled to movement of
substances		 F
RCA
SceS000005817
GO:0006200 ATP catabolic process P
IGI
SpoSPAC29A4.19c
ISS
SpoSPCC1672.11c
GO:0006874 cellular calcium ion homeostasis P
IGI
SpoSPAC29A4.19c
GO:0008150 biological_process P
ND
SceS000005817
GO:0010961 cellular magnesium ion homeostasis P
IGI
SpoSPAC29A4.19c
GO:0015693 magnesium ion transport P
IGI
SpoSPAC29A4.19c
GO:0055085 transmembrane transport P
ISS
SpoSPCC1672.11c
GO:0070588 calcium ion transmembrane transport P
IGI
SpoSPAC29A4.19c

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
23455

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) ATP13A3 GI:148839292
Pan troglodytes (Ptr) ATP13A3 GI:114591176
Canis familiaris (Cfa) ATP13A3 GI:74002986
Mus musculus (Mmu) Atp13a3
(MGI:2685387)		 GI:149267516 Q5XF89
Gallus gallus (Gga) ATP13A3 GI:118095112
Drosophila melanogaster (Dme) CG32000
(FBgn0052000)		 GI:45552131
Anopheles gambiae (Aga) AgaP_AGAP011271 GI:158287321
Caenorhabditis elegans (Cel) Y59H11AR.2
(CE29894;
WBGene00022010)		 GI:71999370
Caenorhabditis elegans (Cel) W08D2.5
(CE32950;
WBGene00012341)		 GI:32565965
Caenorhabditis elegans (Cel) K07E3.7
(CE37253;
WBGene00019493)		 GI:71993281
Schizosaccharomyces pombe (Spo) SPCC1672.11c GI:19075382 O74431
Saccharomyces cerevisiae (Sce) YOR291W
(S000005817)		 GI:6324865 Q12697
Kluyveromyces lactis (Kla) KLLA0B08217g GI:50303897
Eremothecium gossypii (Ego) AGOS_AFR567W GI:45199085
Magnaporthe grisea (Mgr) MGG_06925 GI:39978081
Neurospora crassa (Ncr) NCU01437.1 GI:32414793
Plasmodium falciparum (Pfa) PFE0805w GI:124506241


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000329 fungal-type vacuole membrane C
IDA
SceS000005817
GO:0005575 cellular_component C
ND
MmuMGI:2685387
GO:0005774 vacuolar membrane C
ISS
CelWBGene00012341
GO:0005783 endoplasmic reticulum C
IDA
SpoSPCC1672.11c
GO:0016021 integral to membrane C
ISS
DmeFBgn0052000
TAS
PfaPFE0805w
GO:0020011 apicoplast C
RCA
PfaPFE0805w
GO:0003674 molecular_function F
ND
MmuMGI:2685387
SceS000005817
GO:0008324 cation transmembrane transporter
activity		 F
TAS
PfaPFE0805w
GO:0015075 ion transmembrane transporter activity F
RCA
SceS000005817
GO:0015399 primary active transmembrane transporter
activity		 F
RCA
SceS000005817
GO:0015405 P-P-bond-hydrolysis-driven transmembrane
transporter activity		 F
RCA
SceS000005817
GO:0015662 ATPase activity, coupled to transmembrane movement
of ions, phosphorylative mechanism		 F
RCA
SceS000005817
GO:0016820 hydrolase activity, acting on acid anhydrides,
catalyzing transmembrane movement of
substances		 F
RCA
SceS000005817
GO:0016887 ATPase activity F
RCA
SceS000005817
GO:0022804 active transmembrane transporter
activity		 F
RCA
SceS000005817
GO:0022857 transmembrane transporter activity F
RCA
SceS000005817
GO:0022891 substrate-specific transmembrane transporter
activity		 F
RCA
SceS000005817
GO:0042623 ATPase activity, coupled F
RCA
SceS000005817
GO:0042625 ATPase activity, coupled to transmembrane movement
of ions		 F
ISS
DmeFBgn0052000
RCA
SceS000005817
GO:0042626 ATPase activity, coupled to transmembrane movement
of substances		 F
ISS
SpoSPCC1672.11c
RCA
SceS000005817
GO:0043492 ATPase activity, coupled to movement of
substances		 F
RCA
SceS000005817
GO:0000003 reproduction P
IMP
CelWBGene00012341
GO:0006200 ATP catabolic process P
ISS
SpoSPCC1672.11c
GO:0006457 protein folding P
IGI
CelWBGene00012341
GO:0006812 cation transport P
ISS
DmeFBgn0052000
TAS
PfaPFE0805w
GO:0008150 biological_process P
ND
MmuMGI:2685387
SceS000005817
GO:0055085 transmembrane transport P
ISS
SpoSPCC1672.11c

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_187

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga8323 ENSANGP00000008260
Ashbya gossypii (Ago) ago3759 AFR567W
Caenorhabditis elegans (Cel) cel12150 K07E3.7a
(CE37253;
WBGene00019493)
Caenorhabditis elegans (Cel) cel12151 K07E3.7b
(CE37254)
Caenorhabditis elegans (Cel) cel17240 W08D2.5
(CE32950;
WBGene00012341)
Caenorhabditis elegans (Cel) cel20156 Y59H11AR.2a
(CE29894;
WBGene00022010)
Caenorhabditis elegans (Cel) cel20157 Y59H11AR.2b
(CE33894)
Candida glabrata (Cgl) cgl5146 CAGL0M11308g
Cryptococcus neoformans (Cne) cne886 163.m06270
Dictyostelium discoideum (Ddi) ddi9903 DDB0186223
Dictyostelium discoideum (Ddi) ddi7719 DDB0186277
Dictyostelium discoideum (Ddi) ddi5063 DDB0218156
Debaryomyces hansenii (Dha) dha5880 DEHA0G04147g
Drosophila melanogaster (Dme) dme15491 CG32000-PA
(FBgn0052000)
Drosophila melanogaster (Dme) dme15490 CG32000-PB
(FBgn0052000)
Drosophila melanogaster (Dme) dme15488 CG32000-PC
(FBgn0052000)
Drosophila melanogaster (Dme) dme15487 CG32000-PD
(FBgn0052000)
Drosophila melanogaster (Dme) dme15489 CG32000-PE
(FBgn0052000)
Drosophila melanogaster (Dme) dme15492 CG32000-PF
(FBgn0052000)
Drosophila melanogaster (Dme) dme15486 CG32000-PG
(FBgn0052000)
Danio rerio (Dre) dre15652 ENSDARP00000011183
Encephalitozoon cuniculi (Ecu) ecu1958 19074572
Takifugu rubripes (Fru) fru17175 SINFRUP00000130506
Takifugu rubripes (Fru) fru28335 SINFRUP00000131248
Takifugu rubripes (Fru) fru24514 SINFRUP00000160771
Takifugu rubripes (Fru) fru24516 SINFRUP00000160773
Takifugu rubripes (Fru) fru24515 SINFRUP00000160774
Takifugu rubripes (Fru) fru17178 SINFRUP00000166704
Takifugu rubripes (Fru) fru17176 SINFRUP00000170110
Takifugu rubripes (Fru) fru17174 SINFRUP00000174110
Takifugu rubripes (Fru) fru28336 SINFRUP00000174529
Takifugu rubripes (Fru) fru17177 SINFRUP00000175031
Takifugu rubripes (Fru) fru28337 SINFRUP00000175811
Gallus gallus (Gga) gga12548 ENSGALP00000005975
Gallus gallus (Gga) gga12549 ENSGALP00000005976
Gallus gallus (Gga) gga12547 ENSGALP00000005977
(ATP13A2)
Gallus gallus (Gga) gga23440 ENSGALP00000011446
(ATP13A3)
Gallus gallus (Gga) gga23441 ENSGALP00000011447
Gallus gallus (Gga) gga23457 ENSGALP00000011608
(ATP13A5)
Gallus gallus (Gga) gga23455 ENSGALP00000011609
Gallus gallus (Gga) gga23456 ENSGALP00000011610
(ATP13A4)		 Q5ZKB7
Gallus gallus (Gga) gga23458 ENSGALP00000011611
Homo sapiens (Hsa) hsa23645 ENSP00000256031
(ATP13A3)		 Q9H7F0-1
Homo sapiens (Hsa) hsa23634 ENSP00000295548
(ATP13A4)		 Q4VNC1-3
Homo sapiens (Hsa) hsa23644 ENSP00000311019
(ATP13A3)		 C9JN92
Homo sapiens (Hsa) hsa408 ENSP00000327214
(ATP13A2)		 Q9NQ11-1
Homo sapiens (Hsa) hsa407 ENSP00000341115
(ATP13A2)		 Q9NQ11-2
Homo sapiens (Hsa) hsa409 ENSP00000350528
Kluyveromyces lactis (Kla) kla894 KLLA0B08217g
Mus musculus (Mmu) mmu10181 ENSMUSP00000036675
Mus musculus (Mmu) mmu19235 ENSMUSP00000039648
(MGI:1922022)		 A2AA78
Mus musculus (Mmu) mmu10169 ENSMUSP00000048753
(MGI:1924456)		 Q5XF90-4
Mus musculus (Mmu) mmu10179 ENSMUSP00000051645
(MGI:2685387)		 Q5XF89-1
Mus musculus (Mmu) mmu10168 ENSMUSP00000060987
(MGI:1924456)		 Q5XF90-1
Mus musculus (Mmu) mmu10180 ENSMUSP00000073129
Mus musculus (Mmu) mmu10167 ENSMUSP00000075204
(MGI:2444068)		 Q3TYU2-1
Neurospora crassa (Ncr) ncr9855 NCU10143.2
Plasmodium falciparum (Pfa) pfa3490 PFE0195w
Plasmodium falciparum (Pfa) pfa3610 PFE0805w
Rattus norvegicus (Rno) rno7449 ENSRNOP00000002333
(RGD:1306927)
Rattus norvegicus (Rno) rno7448 ENSRNOP00000002336
(RGD:1306927)
Rattus norvegicus (Rno) rno7430 ENSRNOP00000002350
(GI:360728)
Rattus norvegicus (Rno) rno24256 ENSRNOP00000010884
(RGD:1307977)		 B5DEH6
Rattus norvegicus (Rno) rno7431 ENSRNOP00000035706
Rattus norvegicus (Rno) rno7454 ENSRNOP00000036765
(RGD:1306792)
Rattus norvegicus (Rno) rno7455 ENSRNOP00000043434
Rattus norvegicus (Rno) rno7428 ENSRNOP00000045044
Rattus norvegicus (Rno) rno7452 ENSRNOP00000047215
Rattus norvegicus (Rno) rno7429 ENSRNOP00000047452
Rattus norvegicus (Rno) rno7432 ENSRNOP00000050540
Saccharomyces cerevisiae (Sce) sce6037 YOR291W
(S000005817)
Schizosaccharomyces pombe (Spo) spo523 SPAC29A4.19c O14022
Schizosaccharomyces pombe (Spo) spo4379 SPCC1672.11c O74431
Yarrowia lipolytica (Yli) yli3679 YALI0D23265g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000329 fungal-type vacuole membrane C
IDA
SceS000005817
GO:0005575 cellular_component C
ND
MmuMGI:2685387
MGI:1924456
MGI:1922022
MGI:2444068
GO:0005774 vacuolar membrane C
ISS
CelWBGene00012341
GO:0005783 endoplasmic reticulum C
IDA
SpoSPCC1672.11c
SPAC29A4.19c
GO:0005794 Golgi apparatus C
IDA
SpoSPAC29A4.19c
GO:0016021 integral to membrane C
ISS
DmeFBgn0052000
TAS
PfaPFE0805w
GO:0020011 apicoplast C
RCA
PfaPFE0805w
GO:0003674 molecular_function F
ND
MmuMGI:2685387
MGI:1922022
MGI:2444068
MGI:1924456
SceS000005817
GO:0005388 calcium-transporting ATPase activity F
IGI
SpoSPAC29A4.19c
GO:0008324 cation transmembrane transporter
activity		 F
ISS
PfaPFE0195w
TAS
PfaPFE0805w
GO:0015075 ion transmembrane transporter activity F
RCA
SceS000005817
GO:0015399 primary active transmembrane transporter
activity		 F
RCA
SceS000005817
GO:0015405 P-P-bond-hydrolysis-driven transmembrane
transporter activity		 F
RCA
SceS000005817
GO:0015662 ATPase activity, coupled to transmembrane movement
of ions, phosphorylative mechanism		 F
RCA
SceS000005817
GO:0016820 hydrolase activity, acting on acid anhydrides,
catalyzing transmembrane movement of
substances		 F
RCA
SceS000005817
GO:0016887 ATPase activity F
RCA
SceS000005817
GO:0022804 active transmembrane transporter
activity		 F
RCA
SceS000005817
GO:0022857 transmembrane transporter activity F
RCA
SceS000005817
GO:0022891 substrate-specific transmembrane transporter
activity		 F
RCA
SceS000005817
GO:0042623 ATPase activity, coupled F
RCA
SceS000005817
GO:0042625 ATPase activity, coupled to transmembrane movement
of ions		 F
ISS
DmeFBgn0052000
RCA
SceS000005817
GO:0042626 ATPase activity, coupled to transmembrane movement
of substances		 F
ISS
SpoSPCC1672.11c
RCA
SceS000005817
GO:0043492 ATPase activity, coupled to movement of
substances		 F
RCA
SceS000005817
GO:0000003 reproduction P
IMP
CelWBGene00012341
GO:0006200 ATP catabolic process P
IGI
SpoSPAC29A4.19c
ISS
SpoSPCC1672.11c
GO:0006457 protein folding P
IGI
CelWBGene00012341
GO:0006812 cation transport P
ISS
DmeFBgn0052000
PfaPFE0195w
TAS
PfaPFE0805w
GO:0006874 cellular calcium ion homeostasis P
IGI
SpoSPAC29A4.19c
GO:0008150 biological_process P
ND
MmuMGI:2685387
MGI:2444068
MGI:1924456
MGI:1922022
SceS000005817
GO:0010961 cellular magnesium ion homeostasis P
IGI
SpoSPAC29A4.19c
GO:0015693 magnesium ion transport P
IGI
SpoSPAC29A4.19c
GO:0055085 transmembrane transport P
ISS
SpoSPCC1672.11c
GO:0070588 calcium ion transmembrane transport P
IGI
SpoSPAC29A4.19c

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPCC1672.11c
(O74431)		 YOR291W
(S000005817)
SPAC29A4.19c
(O14022)		 YOR291W
(S000005817)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000329 fungal-type vacuole membrane C
IDA
SceS000005817
GO:0005783 endoplasmic reticulum C
IDA
SpoSPCC1672.11c
SPAC29A4.19c
GO:0005794 Golgi apparatus C
IDA
SpoSPAC29A4.19c
GO:0003674 molecular_function F
ND
SceS000005817
GO:0005388 calcium-transporting ATPase activity F
IGI
SpoSPAC29A4.19c
GO:0015075 ion transmembrane transporter activity F
RCA
SceS000005817
GO:0015399 primary active transmembrane transporter
activity		 F
RCA
SceS000005817
GO:0015405 P-P-bond-hydrolysis-driven transmembrane
transporter activity		 F
RCA
SceS000005817
GO:0015662 ATPase activity, coupled to transmembrane movement
of ions, phosphorylative mechanism		 F
RCA
SceS000005817
GO:0016820 hydrolase activity, acting on acid anhydrides,
catalyzing transmembrane movement of
substances		 F
RCA
SceS000005817
GO:0016887 ATPase activity F
RCA
SceS000005817
GO:0022804 active transmembrane transporter
activity		 F
RCA
SceS000005817
GO:0022857 transmembrane transporter activity F
RCA
SceS000005817
GO:0022891 substrate-specific transmembrane transporter
activity		 F
RCA
SceS000005817
GO:0042623 ATPase activity, coupled F
RCA
SceS000005817
GO:0042625 ATPase activity, coupled to transmembrane movement
of ions		 F
RCA
SceS000005817
GO:0042626 ATPase activity, coupled to transmembrane movement
of substances		 F
ISS
SpoSPCC1672.11c
RCA
SceS000005817
GO:0043492 ATPase activity, coupled to movement of
substances		 F
RCA
SceS000005817
GO:0006200 ATP catabolic process P
IGI
SpoSPAC29A4.19c
ISS
SpoSPCC1672.11c
GO:0006874 cellular calcium ion homeostasis P
IGI
SpoSPAC29A4.19c
GO:0008150 biological_process P
ND
SceS000005817
GO:0010961 cellular magnesium ion homeostasis P
IGI
SpoSPAC29A4.19c
GO:0015693 magnesium ion transport P
IGI
SpoSPAC29A4.19c
GO:0055085 transmembrane transport P
ISS
SpoSPCC1672.11c
GO:0070588 calcium ion transmembrane transport P
IGI
SpoSPAC29A4.19c

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