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Search term: YOR306C

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name MCH5
SGD link S000005833
Alternative ID YOR306C
Description Plasma membrane riboflavin transporter; facilitates the uptake of vitamin B2; required for FAD-dependent processes; sequence similarity to mammalian monocarboxylate permeases, however mutants are not deficient in monocarboxylate transport
Synonyms YOR306C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG2504 -CDHY--

KOGs classification KOGs description
METABOLISM Monocarboxylate transporter

Species KOG link NCBI link UniProt link
Homo sapiens (Hsa) Hs18699730
(SLC16A10)		 GI:18699730 Q8TF71
Homo sapiens (Hsa) Hs19923753 GI:19923753
Homo sapiens (Hsa) Hs20472343 GI:20472343
Homo sapiens (Hsa) Hs20474082 GI:20474082
Homo sapiens (Hsa) Hs22049062 GI:22049062
Homo sapiens (Hsa) Hs22064599 GI:22064599
Homo sapiens (Hsa) Hs20559959 GI:20559959
Homo sapiens (Hsa) Hs18553168 GI:18553168
Caenorhabditis elegans (Cel) CE02803 GI:17568709
Drosophila melanogaster (Dme) 7292012
(FBgn0035173)		 GI:19923028
Drosophila melanogaster (Dme) 7290288 GI:7290288
Caenorhabditis elegans (Cel) CE12336
(WBGene00010834)		 GI:17568977 Q93896
Caenorhabditis elegans (Cel) CE04864
(WBGene00020168)		 GI:17535933 Q22109
Homo sapiens (Hsa) Hs4759120 GI:4759120
Drosophila melanogaster (Dme) 7302291 GI:7302291
Homo sapiens (Hsa) Hs4759116
(SLC16A5)		 GI:4759116 O15375
Drosophila melanogaster (Dme) 7303156 GI:7303156
Homo sapiens (Hsa) Hs4759114
(SLC16A4)		 GI:4759114 O15374
Homo sapiens (Hsa) Hs4759112 GI:4759112 O15427
Saccharomyces cerevisiae (Sce) YNL125c
(S000005069)		 GI:6324204 P53918
Caenorhabditis elegans (Cel) CE05457 GI:17551098
Caenorhabditis elegans (Cel) CE29573
(WBGene00015676)		 GI:17550316 O17328
Caenorhabditis elegans (Cel) CE20478
(WBGene00015273)		 GI:17557434 Q9UAT3
Drosophila melanogaster (Dme) 7295764
(FBgn0031568)		 GI:20129213
Drosophila melanogaster (Dme) 7293576
(out)		 GI:18860535 Q9V3F9
Drosophila melanogaster (Dme) 7293575 GI:7293575
Drosophila melanogaster (Dme) 7293565 GI:7293565
Drosophila melanogaster (Dme) 7303562 GI:7303562
Drosophila melanogaster (Dme) 7293573 GI:7293573
Drosophila melanogaster (Dme) 7303008 GI:7303008 Q0E960
Drosophila melanogaster (Dme) 7302232 GI:7302232
Homo sapiens (Hsa) Hs4759118 GI:4759118
Homo sapiens (Hsa) Hs7019529 GI:7019529
Drosophila melanogaster (Dme) 7303213
(FBgn0033913)		 GI:19922230 Q7K1L4
Saccharomyces cerevisiae (Sce) YKL221w
(S000001704)		 GI:6322628 P36032
Saccharomyces cerevisiae (Sce) YOL119c
(S000005479)		 GI:6324453 Q08268
Caenorhabditis elegans (Cel) CE28872 GI:17566092
Caenorhabditis elegans (Cel) CE03442 GI:17568321
Drosophila melanogaster (Dme) 7293574 GI:18860531
Drosophila melanogaster (Dme) 7299667 GI:7299667
Homo sapiens (Hsa) Hs5730045
(SLC16A2)		 GI:5730045 P36021
Saccharomyces cerevisiae (Sce) YOR306c
(S000005833)		 GI:6324882 Q08777
Caenorhabditis elegans (Cel) CE27947
(WBGene00017369)		 GI:17533091
Caenorhabditis elegans (Cel) CE21446 GI:17565296


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000329 fungal-type vacuole membrane C
IDA
SceS000005479
GO:0005624 membrane fraction C
TAS
HsaSLC16A4
SLC16A5
SLC16A2
GO:0005739 mitochondrion C
IDA
SceS000005069
GO:0005886 plasma membrane C
IDA
SceS000005833
GO:0005887 integral to plasma membrane C
TAS
HsaSLC16A4
SLC16A5
SLC16A2
GO:0016020 membrane C
ISS
SceS000005069
S000001704
GO:0016323 basolateral plasma membrane C
TAS
HsaSLC16A10
GO:0005215 transporter activity F
ISS
SceS000001704
S000005069
S000005479
TAS
HsaSLC16A2
GO:0008028 monocarboxylic acid transmembrane transporter
activity		 F
ISS
DmeFBgn0031568
out
TAS
HsaSLC16A5
SLC16A4
SLC16A2
GO:0015355 secondary active monocarboxylate transmembrane
transporter activity		 F
ISS
DmeFBgn0035173
NAS
DmeFBgn0033913
GO:0032217 riboflavin transporter activity F
IGI
SceS000005833
GO:0000003 reproduction P
IMP
CelWBGene00015676
GO:0002119 nematode larval development P
IMP
CelWBGene00015676
GO:0006082 organic acid metabolic process P
RCA
SceS000005479
GO:0006519 cellular amino acid and derivative metabolic
process		 P
RCA
SceS000005479
GO:0006725 cellular aromatic compound metabolic
process		 P
RCA
SceS000005479
GO:0006807 nitrogen compound metabolic process P
RCA
SceS000005479
GO:0006810 transport P
ISS
SceS000005069
S000001704
S000005479
TAS
HsaSLC16A2
GO:0006865 amino acid transport P
EXP
HsaSLC16A10
GO:0007281 germ cell development P
IMP
Dmeout
GO:0012501 programmed cell death P
IMP
Dmeout
GO:0015718 monocarboxylic acid transport P
TAS
HsaSLC16A2
SLC16A5
SLC16A4
GO:0015801 aromatic amino acid transport P
TAS
HsaSLC16A10
GO:0032218 riboflavin transport P
IGI
SceS000005833
GO:0035234 germ cell programmed cell death P
TAS
Dmeout
GO:0040007 growth P
IMP
CelWBGene00015676
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00017369

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
74834

Species Gene ID NCBI link UniProt link
Saccharomyces cerevisiae (Sce) MCH5
(S000005833)		 GI:6324882 Q08777
Kluyveromyces lactis (Kla) KLLA0F08525g GI:50310889
Magnaporthe grisea (Mgr) MGG_02724 GI:39970515
Magnaporthe grisea (Mgr) MGG_10881 GI:145601561
Neurospora crassa (Ncr) NCU06167.1 GI:32411083


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005886 plasma membrane C
IDA
SceS000005833
GO:0032217 riboflavin transporter activity F
IGI
SceS000005833
GO:0032218 riboflavin transport P
IGI
SceS000005833

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_29474

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Candida glabrata (Cgl) cgl2940 CAGL0I09702g
Candida glabrata (Cgl) cgl2941 CAGL0I09724g
Kluyveromyces lactis (Kla) kla4467 KLLA0F08525g
Saccharomyces cerevisiae (Sce) sce6055 YOR306C
(S000005833)


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005886 plasma membrane C
IDA
SceS000005833
GO:0032217 riboflavin transporter activity F
IGI
SceS000005833
GO:0032218 riboflavin transport P
IGI
SceS000005833

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s.khadayate@ucl.ac.uk