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Search term: YOR330C

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name MIP1
SGD link S000005857
Alternative ID YOR330C
Description Catalytic subunit of the mitochondrial DNA polymerase; conserved C-terminal segment is required for the maintenance of mitochondrial genome; related to human POLG, which has been associated with mitochondrial diseases
Synonyms YOR330C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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Search for GO info:  

GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG3657 -CDHYP-

KOGs classification KOGs description
INFORMATION STORAGE AND PROCESSING Mitochondrial DNA polymerase gamma, catalytic subunit

Species KOG link NCBI link UniProt link
Caenorhabditis elegans (Cel) CE25501
(WBGene00013258)		 GI:17537597 Q9U208
Drosophila melanogaster (Dme) 7298099
(FBgn0004406)		 GI:17136648
Homo sapiens (Hsa) Hs4505937 GI:4505937 Q6LCA9
Saccharomyces cerevisiae (Sce) YOR330c
(S000005857)		 GI:6324906
Schizosaccharomyces pombe (Spo) SPCC24B10.22 GI:19075525 Q12704


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005739 mitochondrion C
IDA
SceS000005857
SpoSPCC24B10.22
ISS
DmeFBgn0004406
NAS
DmeFBgn0004406
GO:0005760 gamma DNA polymerase complex C
IDA
DmeFBgn0004406
ISS
DmeFBgn0004406
GO:0003677 DNA binding F
IDA
SceS000005857
IMP
SceS000005857
ISS
SpoSPCC24B10.22
GO:0003887 DNA-directed DNA polymerase activity F
IDA
DmeFBgn0004406
SceS000005857
ISS
DmeFBgn0004406
SpoSPCC24B10.22
NAS
DmeFBgn0004406
GO:0008296 3'-5'-exodeoxyribonuclease activity F
NAS
DmeFBgn0004406
GO:0008408 3'-5' exonuclease activity F
IDA
SceS000005857
GO:0000002 mitochondrial genome maintenance P
IMP
SpoSPCC24B10.22
GO:0000003 reproduction P
IMP
CelWBGene00013258
GO:0006261 DNA-dependent DNA replication P
IDA
DmeFBgn0004406
SceS000005857
IMP
SceS000005857
ISS
DmeFBgn0004406
NAS
DmeFBgn0004406
GO:0006264 mitochondrial DNA replication P
IDA
SceS000005857
IMP
CelWBGene00013258
ISS
SpoSPCC24B10.22
TAS
DmeFBgn0004406
GO:0007005 mitochondrion organization P
IMP
CelWBGene00013258
SpoSPCC24B10.22
GO:0007562 eclosion P
NAS
DmeFBgn0004406
GO:0008340 determination of adult lifespan P
IMP
CelWBGene00013258
NAS
DmeFBgn0004406
GO:0008406 gonad development P
IMP
CelWBGene00013258
GO:0030421 defecation P
IMP
CelWBGene00013258

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
2016

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) POLG GI:187171277
Pan troglodytes (Ptr) POLG GI:114658821
Canis familiaris (Cfa) POLG GI:73951465
Mus musculus (Mmu) Polg
(MGI:1196389)		 GI:87080815 P54099
Rattus norvegicus (Rno) Polg
(RGD:620057)		 GI:16758292
Gallus gallus (Gga) POLG GI:118095896
Drosophila melanogaster (Dme) tam
(FBgn0004406)		 GI:17136648
Anopheles gambiae (Aga) AgaP_AGAP000139 GI:158289252
Schizosaccharomyces pombe (Spo) SPCPB16A4.01 GI:63054429
Saccharomyces cerevisiae (Sce) MIP1
(S000005857)		 GI:83578108
Kluyveromyces lactis (Kla) KLLA0F02574g GI:50310355
Eremothecium gossypii (Ego) AGOS_ADR357C GI:45188230
Magnaporthe grisea (Mgr) MGG_08913 GI:145614196
Neurospora crassa (Ncr) NCU00276.1 GI:32403498


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005739 mitochondrion C
IDA
MmuMGI:1196389
SceS000005857
ISO
MmuMGI:1196389
ISS
DmeFBgn0004406
NAS
DmeFBgn0004406
GO:0005743 mitochondrial inner membrane C
IDA
MmuMGI:1196389
GO:0005760 gamma DNA polymerase complex C
IDA
DmeFBgn0004406
ISO
MmuMGI:1196389
ISS
DmeFBgn0004406
GO:0042645 mitochondrial nucleoid C
IDA
HsaPOLG
GO:0002020 protease binding F
IPI
HsaPOLG
GO:0003677 DNA binding F
IDA
SceS000005857
IMP
SceS000005857
GO:0003887 DNA-directed DNA polymerase activity F
IDA
DmeFBgn0004406
HsaPOLG
SceS000005857
ISO
MmuMGI:1196389
ISS
DmeFBgn0004406
NAS
DmeFBgn0004406
GO:0004527 exonuclease activity F
IDA
MmuMGI:1196389
GO:0005515 protein binding F
IPI
HsaPOLG
MmuMGI:1196389
GO:0008296 3'-5'-exodeoxyribonuclease activity F
NAS
DmeFBgn0004406
GO:0008408 3'-5' exonuclease activity F
IDA
SceS000005857
GO:0006259 DNA metabolic process P
TAS
HsaPOLG
GO:0006261 DNA-dependent DNA replication P
IDA
DmeFBgn0004406
SceS000005857
IMP
SceS000005857
ISS
DmeFBgn0004406
NAS
DmeFBgn0004406
TAS
HsaPOLG
GO:0006264 mitochondrial DNA replication P
IDA
SceS000005857
IMP
MmuMGI:1196389
TAS
DmeFBgn0004406
GO:0006287 base-excision repair, gap-filling P
IDA
HsaPOLG
GO:0007562 eclosion P
NAS
DmeFBgn0004406
GO:0007568 aging P
IMP
MmuMGI:1196389
GO:0008152 metabolic process P
IDA
MmuMGI:1196389
ISO
MmuMGI:1196389
GO:0008340 determination of adult lifespan P
NAS
DmeFBgn0004406

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_2801

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga14711 ENSANGP00000008130
Ashbya gossypii (Ago) ago2098 ADR357C
Caenorhabditis elegans (Cel) cel19966 Y57A10A.15
(CE25501;
WBGene00013258)
Candida glabrata (Cgl) cgl1173 CAGL0E05324g
Cryptococcus neoformans (Cne) cne4600 186.m03441
Debaryomyces hansenii (Dha) dha4993 DEHA0F13728g
Drosophila melanogaster (Dme) dme2325 CG8987-PA
(FBgn0004406)
Danio rerio (Dre) dre29326 ENSDARP00000019589
Danio rerio (Dre) dre29330 ENSDARP00000031752
Danio rerio (Dre) dre29327 ENSDARP00000033728
Danio rerio (Dre) dre29328 ENSDARP00000034988
Danio rerio (Dre) dre29329 ENSDARP00000050367
Takifugu rubripes (Fru) fru28393 SINFRUP00000144291
Takifugu rubripes (Fru) fru28397 SINFRUP00000169648
Takifugu rubripes (Fru) fru28394 SINFRUP00000170089
Takifugu rubripes (Fru) fru28396 SINFRUP00000171160
Takifugu rubripes (Fru) fru28395 SINFRUP00000175796
Gallus gallus (Gga) gga4040 ENSGALP00000010715
Gallus gallus (Gga) gga4041 ENSGALP00000010716
(POLG)		 Q92076
Homo sapiens (Hsa) hsa11158 ENSP00000268124
(POLG)		 P54098
Kluyveromyces lactis (Kla) kla4196 KLLA0F02574g
Mus musculus (Mmu) mmu24218 ENSMUSP00000035345
(MGI:1196389)		 P54099
Mus musculus (Mmu) mmu24219 ENSMUSP00000073551
(MGI:1196389)		 Q05BB8
Neurospora crassa (Ncr) ncr264 NCU00276.2
Rattus norvegicus (Rno) rno2142 ENSRNOP00000046374
Rattus norvegicus (Rno) rno2141 ENSRNOP00000047900
(RGD:620057)		 Q9QYV8
Saccharomyces cerevisiae (Sce) sce6082 YOR330C
(S000005857)
Schizosaccharomyces pombe (Spo) spo3073 SPCC24B10.22 Q12704
Yarrowia lipolytica (Yli) yli6157 YALI0F19404g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005739 mitochondrion C
IDA
MmuMGI:1196389
SceS000005857
SpoSPCC24B10.22
ISO
MmuMGI:1196389
ISS
DmeFBgn0004406
NAS
DmeFBgn0004406
GO:0005743 mitochondrial inner membrane C
IDA
MmuMGI:1196389
GO:0005760 gamma DNA polymerase complex C
IDA
DmeFBgn0004406
ISO
MmuMGI:1196389
ISS
DmeFBgn0004406
GO:0003677 DNA binding F
IDA
SceS000005857
IMP
SceS000005857
ISS
SpoSPCC24B10.22
GO:0003887 DNA-directed DNA polymerase activity F
IDA
DmeFBgn0004406
SceS000005857
ISO
MmuMGI:1196389
ISS
DmeFBgn0004406
SpoSPCC24B10.22
NAS
DmeFBgn0004406
GO:0004527 exonuclease activity F
IDA
MmuMGI:1196389
GO:0005515 protein binding F
IPI
MmuMGI:1196389
GO:0008296 3'-5'-exodeoxyribonuclease activity F
NAS
DmeFBgn0004406
GO:0008408 3'-5' exonuclease activity F
IDA
SceS000005857
GO:0000002 mitochondrial genome maintenance P
IMP
SpoSPCC24B10.22
GO:0000003 reproduction P
IMP
CelWBGene00013258
GO:0006261 DNA-dependent DNA replication P
IDA
DmeFBgn0004406
SceS000005857
IMP
SceS000005857
ISS
DmeFBgn0004406
NAS
DmeFBgn0004406
GO:0006264 mitochondrial DNA replication P
IDA
SceS000005857
IMP
CelWBGene00013258
MmuMGI:1196389
ISS
SpoSPCC24B10.22
TAS
DmeFBgn0004406
GO:0007005 mitochondrion organization P
IMP
CelWBGene00013258
SpoSPCC24B10.22
GO:0007562 eclosion P
NAS
DmeFBgn0004406
GO:0007568 aging P
IMP
MmuMGI:1196389
GO:0008152 metabolic process P
IDA
MmuMGI:1196389
ISO
MmuMGI:1196389
GO:0008340 determination of adult lifespan P
IMP
CelWBGene00013258
NAS
DmeFBgn0004406
GO:0008406 gonad development P
IMP
CelWBGene00013258
GO:0030421 defecation P
IMP
CelWBGene00013258

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPCC24B10.22
(Q12704)		 YOR330C
(S000005857)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005739 mitochondrion C
IDA
SceS000005857
SpoSPCC24B10.22
GO:0003677 DNA binding F
IDA
SceS000005857
IMP
SceS000005857
ISS
SpoSPCC24B10.22
GO:0003887 DNA-directed DNA polymerase activity F
IDA
SceS000005857
ISS
SpoSPCC24B10.22
GO:0008408 3'-5' exonuclease activity F
IDA
SceS000005857
GO:0000002 mitochondrial genome maintenance P
IMP
SpoSPCC24B10.22
GO:0006261 DNA-dependent DNA replication P
IDA
SceS000005857
IMP
SceS000005857
GO:0006264 mitochondrial DNA replication P
IDA
SceS000005857
ISS
SpoSPCC24B10.22
GO:0007005 mitochondrion organization P
IMP
SpoSPCC24B10.22

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Search for gene by ID or name:

Query species:

Include wild-cards:   

Search for GO info:  

GO info in one table:

s.khadayate@ucl.ac.uk