YOGY Home YOGY Help

Search term: YOR332W

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name VMA4
SGD link S000005859
Alternative ID YOR332W
Description Subunit E of the eight-subunit V1 peripheral membrane domain of the vacuolar H+-ATPase (V-ATPase), an electrogenic proton pump found throughout the endomembrane system; required for the V1 domain to assemble onto the vacuolar membrane
Synonyms YOR332W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

Search for gene by ID or name:

Query species:

Include wild-cards:   

Search for GO info:  

GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG1664 ACDHYPE

KOGs classification KOGs description
METABOLISM Vacuolar H+-ATPase V1 sector, subunit E

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At1g64200 GI:15222641
Arabidopsis thaliana (Ath) At3g08560 GI:15231933
Arabidopsis thaliana (Ath) At4g11150 GI:15237054
Caenorhabditis elegans (Cel) CE19362
(WBGene00006917)		 GI:17538698 Q95X44
Drosophila melanogaster (Dme) 7296718
(FBgn0015324)		 GI:17737775
Homo sapiens (Hsa) Hs18087815
(ATP6V1E2)		 GI:18087815 Q96A05
Homo sapiens (Hsa) Hs4502317
(ATP6V1E1)		 GI:4502317 P36543
Homo sapiens (Hsa) Hs18549288 GI:18549288
Saccharomyces cerevisiae (Sce) YOR332w
(S000005859)		 GI:6324907 P22203
Schizosaccharomyces pombe (Spo) SPAC11E3.07 GI:19115844 O13687
Encephalitozoon cuniculi (Ecu) ECU05g0405 GI:19173578 Q8SRZ2


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000221 vacuolar proton-transporting V-type ATPase, V1
domain		 C
ISS
DmeFBgn0015324
SpoSPAC11E3.07
NAS
DmeFBgn0015324
TAS
SceS000005859
GO:0000325 plant-type vacuole C
IDA
AthAt4g11150
GO:0000329 fungal-type vacuole membrane C
IDA
SpoSPAC11E3.07
TAS
SceS000005859
GO:0005737 cytoplasm C
IDA
CelWBGene00006917
GO:0005753 mitochondrial proton-transporting ATP synthase
complex		 C
ISS
AthAt4g11150
At3g08560
At1g64200
GO:0005768 endosome C
ISS
HsaATP6V1E1
GO:0005773 vacuole C
IDA
AthAt4g11150
At3g08560
At1g64200
GO:0005774 vacuolar membrane C
IDA
AthAt4g11150
GO:0005829 cytosol C
ISS
HsaATP6V1E1
GO:0005886 plasma membrane C
IDA
AthAt4g11150
At1g64200
CelWBGene00006917
DmeFBgn0015324
GO:0009705 plant-type vacuole membrane C
IDA
AthAt4g11150
GO:0016324 apical plasma membrane C
IDA
CelWBGene00006917
ISS
HsaATP6V1E1
GO:0016469 proton-transporting two-sector ATPase
complex		 C
TAS
HsaATP6V1E1
GO:0022626 cytosolic ribosome C
IDA
AthAt4g11150
GO:0005515 protein binding F
IPI
HsaATP6V1E1
GO:0005524 ATP binding F
IC
SpoSPAC11E3.07
GO:0008553 hydrogen-exporting ATPase activity,
phosphorylative mechanism		 F
ISS
AthAt3g08560
DmeFBgn0015324
NAS
DmeFBgn0015324
GO:0046961 proton-transporting ATPase activity, rotational
mechanism		 F
ISS
SpoSPAC11E3.07
TAS
AthAt4g11150
SceS000005859
GO:0000003 reproduction P
IMP
CelWBGene00006917
GO:0002119 nematode larval development P
IMP
CelWBGene00006917
GO:0006811 ion transport P
RCA
SceS000005859
GO:0006898 receptor-mediated endocytosis P
IMP
CelWBGene00006917
GO:0007030 Golgi organization P
IMP
AthAt4g11150
GO:0007035 vacuolar acidification P
ISS
SpoSPAC11E3.07
TAS
SceS000005859
GO:0009117 nucleotide metabolic process P
RCA
SceS000005859
GO:0009409 response to cold P
IEP
AthAt4g11150
GO:0009651 response to salt stress P
IEP
AthAt4g11150
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00006917
GO:0009793 embryo development ending in seed
dormancy		 P
IMP
AthAt4g11150
NAS
AthAt4g11150
GO:0009832 plant-type cell wall biogenesis P
IMP
AthAt4g11150
GO:0015986 ATP synthesis coupled proton transport P
ISS
AthAt3g08560
At1g64200
At4g11150
GO:0015991 ATP hydrolysis coupled proton transport P
IC
SpoSPAC11E3.07
GO:0015992 proton transport P
NAS
DmeFBgn0015324
GO:0018996 molting cycle, collagen and cuticulin-based
cuticle		 P
IMP
CelWBGene00006917
GO:0030728 ovulation P
IMP
CelWBGene00006917
GO:0040007 growth P
IMP
CelWBGene00006917
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00006917
GO:0042742 defense response to bacterium P
IEP
AthAt4g11150
GO:0048477 oogenesis P
IMP
CelWBGene00006917
GO:0050801 ion homeostasis P
RCA
SceS000005859
GO:0070265 necrotic cell death P
IMP
CelWBGene00006917

Back to the top

HomoloGene results:

HomoloGene cluster Phylogenetic pattern
1282

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) ATP6V1E1 GI:4502317 P36543
Pan troglodytes (Ptr) ATP6V1E1 GI:114684967
Canis familiaris (Cfa) ATP6V1E1 GI:57106611
Mus musculus (Mmu) Atp6v1e1
(MGI:894326)		 GI:45504359 P50518
Rattus norvegicus (Rno) Atp6v1e1
(RGD:735157)		 GI:38454230
Gallus gallus (Gga) ATP6V1E1 GI:57525423
Drosophila melanogaster (Dme) Vha26
(FBgn0015324)		 GI:17737775
Anopheles gambiae (Aga) AgaP_AGAP002401 GI:31207169
Caenorhabditis elegans (Cel) vha-8
(CE19362;
WBGene00006917)		 GI:17538698 Q95X44
Schizosaccharomyces pombe (Spo) vma4
(SPAC11E3.07)		 GI:19115844 O13687
Saccharomyces cerevisiae (Sce) VMA4
(S000005859)		 GI:6324907 P22203
Kluyveromyces lactis (Kla) KLLA0F02541g GI:50310351
Magnaporthe grisea (Mgr) MGG_02770 GI:39970607
Neurospora crassa (Ncr) NCU07446.1 GI:32414505
Arabidopsis thaliana (Ath) VHA-E2 GI:15231933
Oryza sativa (Osa) Os05g0480700 GI:115464515
Plasmodium falciparum (Pfa) PFI1670c GI:124507227


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000221 vacuolar proton-transporting V-type ATPase, V1
domain		 C
ISS
DmeFBgn0015324
SpoSPAC11E3.07
NAS
DmeFBgn0015324
TAS
SceS000005859
GO:0000329 fungal-type vacuole membrane C
IDA
SpoSPAC11E3.07
TAS
SceS000005859
GO:0005737 cytoplasm C
IDA
CelWBGene00006917
MmuMGI:894326
GO:0005739 mitochondrion C
IDA
MmuMGI:894326
GO:0005753 mitochondrial proton-transporting ATP synthase
complex		 C
ISS
AthVHA-E2
GO:0005768 endosome C
IDA
MmuMGI:894326
ISS
HsaATP6V1E1
GO:0005773 vacuole C
IDA
AthVHA-E2
GO:0005829 cytosol C
IDA
MmuMGI:894326
ISS
HsaATP6V1E1
GO:0005886 plasma membrane C
IDA
CelWBGene00006917
DmeFBgn0015324
GO:0016324 apical plasma membrane C
IDA
CelWBGene00006917
MmuMGI:894326
ISS
HsaATP6V1E1
GO:0016469 proton-transporting two-sector ATPase
complex		 C
TAS
HsaATP6V1E1
GO:0005515 protein binding F
IPI
HsaATP6V1E1
GO:0005524 ATP binding F
IC
SpoSPAC11E3.07
GO:0008553 hydrogen-exporting ATPase activity,
phosphorylative mechanism		 F
IMP
MmuMGI:894326
ISS
AthVHA-E2
DmeFBgn0015324
NAS
DmeFBgn0015324
GO:0046961 proton-transporting ATPase activity, rotational
mechanism		 F
ISS
SpoSPAC11E3.07
TAS
SceS000005859
GO:0000003 reproduction P
IMP
CelWBGene00006917
GO:0002119 nematode larval development P
IMP
CelWBGene00006917
GO:0006200 ATP catabolic process P
IMP
MmuMGI:894326
GO:0006811 ion transport P
RCA
SceS000005859
GO:0006898 receptor-mediated endocytosis P
IMP
CelWBGene00006917
GO:0007035 vacuolar acidification P
ISS
SpoSPAC11E3.07
TAS
SceS000005859
GO:0009117 nucleotide metabolic process P
RCA
SceS000005859
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00006917
GO:0015986 ATP synthesis coupled proton transport P
ISS
AthVHA-E2
GO:0015991 ATP hydrolysis coupled proton transport P
IC
SpoSPAC11E3.07
IMP
MmuMGI:894326
GO:0015992 proton transport P
NAS
DmeFBgn0015324
GO:0018996 molting cycle, collagen and cuticulin-based
cuticle		 P
IMP
CelWBGene00006917
GO:0030728 ovulation P
IMP
CelWBGene00006917
GO:0040007 growth P
IMP
CelWBGene00006917
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00006917
GO:0048477 oogenesis P
IMP
CelWBGene00006917
GO:0050801 ion homeostasis P
RCA
SceS000005859
GO:0070265 necrotic cell death P
IMP
CelWBGene00006917

Back to the top

OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_1283

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga4576 ENSANGP00000014885
Ashbya gossypii (Ago) ago2099 ADR358W
Arabidopsis thaliana (Ath) ath5632 At1g64200.1
Arabidopsis thaliana (Ath) ath12918 At3g08560.1
Arabidopsis thaliana (Ath) ath18853 At4g11150.1
Caenorhabditis elegans (Cel) cel2322 C17H12.14
(CE19362;
WBGene00006917)
Candida glabrata (Cgl) cgl1174 CAGL0E05346g
Cryptococcus neoformans (Cne) cne2275 181.m08298
Dictyostelium discoideum (Ddi) ddi11845 DDB0185070
Debaryomyces hansenii (Dha) dha925 DEHA0B05423g
Drosophila melanogaster (Dme) dme11055 CG1088-PA
(FBgn0015324)
Drosophila melanogaster (Dme) dme11054 CG1088-PB
(FBgn0015324)
Danio rerio (Dre) dre18015 ENSDARP00000050220
(atp6v1e1)		 Q6NWK4
Encephalitozoon cuniculi (Ecu) ecu1140 19173578
Takifugu rubripes (Fru) fru15438 SINFRUP00000130799
Takifugu rubripes (Fru) fru29822 SINFRUP00000140579
Gallus gallus (Gga) gga1274 ENSGALP00000021250
(ATP6V1E1)		 Q5ZKJ9
Homo sapiens (Hsa) hsa21138 ENSP00000253413
(ATP6V1E1)		 P36543
Homo sapiens (Hsa) hsa17773 ENSP00000304891
(ATP6V1E2)		 Q96A05
Kluyveromyces lactis (Kla) kla4194 KLLA0F02541g
Mus musculus (Mmu) mmu22614 ENSMUSP00000019354
(MGI:894326)		 P50518
Mus musculus (Mmu) mmu12202 ENSMUSP00000065285
(MGI:1922165)		 Q9D593
Neurospora crassa (Ncr) ncr7248 NCU07446.2
Oryza sativa (Osa) osa25025 3836.m00124
Oryza sativa (Osa) osa59330 6520.m00151
Plasmodium falciparum (Pfa) pfa4801 PFI1670c
Rattus norvegicus (Rno) rno22116 ENSRNOP00000016495
(RGD:735157)		 Q6PCU2
Rattus norvegicus (Rno) rno24685 ENSRNOP00000020845
(RGD:1311680)
Saccharomyces cerevisiae (Sce) sce6084 YOR332W
(S000005859)
Schizosaccharomyces pombe (Spo) spo4527 SPAC11E3.07 O13687
Yarrowia lipolytica (Yli) yli6000 YALI0F15631g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000221 vacuolar proton-transporting V-type ATPase, V1
domain		 C
ISS
DmeFBgn0015324
SpoSPAC11E3.07
NAS
DmeFBgn0015324
TAS
SceS000005859
GO:0000325 plant-type vacuole C
IDA
AthAt4g11150
GO:0000329 fungal-type vacuole membrane C
IDA
SpoSPAC11E3.07
TAS
SceS000005859
GO:0001669 acrosomal vesicle C
IDA
MmuMGI:1922165
GO:0005737 cytoplasm C
IDA
CelWBGene00006917
MmuMGI:894326
GO:0005739 mitochondrion C
IDA
MmuMGI:894326
GO:0005753 mitochondrial proton-transporting ATP synthase
complex		 C
ISS
AthAt4g11150
At3g08560
At1g64200
GO:0005768 endosome C
IDA
MmuMGI:894326
GO:0005773 vacuole C
IDA
AthAt4g11150
At3g08560
At1g64200
GO:0005774 vacuolar membrane C
IDA
AthAt4g11150
GO:0005829 cytosol C
IDA
MmuMGI:894326
GO:0005886 plasma membrane C
IDA
AthAt4g11150
At1g64200
CelWBGene00006917
DmeFBgn0015324
GO:0009705 plant-type vacuole membrane C
IDA
AthAt4g11150
GO:0016324 apical plasma membrane C
IDA
CelWBGene00006917
MmuMGI:894326
GO:0022626 cytosolic ribosome C
IDA
AthAt4g11150
GO:0005524 ATP binding F
IC
SpoSPAC11E3.07
GO:0008553 hydrogen-exporting ATPase activity,
phosphorylative mechanism		 F
IMP
MmuMGI:894326
MGI:1922165
ISS
AthAt3g08560
DmeFBgn0015324
NAS
DmeFBgn0015324
GO:0046961 proton-transporting ATPase activity, rotational
mechanism		 F
ISS
SpoSPAC11E3.07
TAS
AthAt4g11150
SceS000005859
GO:0000003 reproduction P
IMP
CelWBGene00006917
GO:0002119 nematode larval development P
IMP
CelWBGene00006917
GO:0006200 ATP catabolic process P
IMP
MmuMGI:894326
MGI:1922165
GO:0006811 ion transport P
RCA
SceS000005859
GO:0006898 receptor-mediated endocytosis P
IMP
CelWBGene00006917
GO:0007030 Golgi organization P
IMP
AthAt4g11150
GO:0007035 vacuolar acidification P
ISS
SpoSPAC11E3.07
TAS
SceS000005859
GO:0009117 nucleotide metabolic process P
RCA
SceS000005859
GO:0009409 response to cold P
IEP
AthAt4g11150
GO:0009651 response to salt stress P
IEP
AthAt4g11150
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00006917
GO:0009793 embryo development ending in seed
dormancy		 P
IMP
AthAt4g11150
NAS
AthAt4g11150
GO:0009832 plant-type cell wall biogenesis P
IMP
AthAt4g11150
GO:0015986 ATP synthesis coupled proton transport P
ISS
AthAt3g08560
At1g64200
At4g11150
GO:0015991 ATP hydrolysis coupled proton transport P
IC
SpoSPAC11E3.07
IMP
MmuMGI:894326
MGI:1922165
GO:0015992 proton transport P
NAS
DmeFBgn0015324
GO:0018996 molting cycle, collagen and cuticulin-based
cuticle		 P
IMP
CelWBGene00006917
GO:0030728 ovulation P
IMP
CelWBGene00006917
GO:0040007 growth P
IMP
CelWBGene00006917
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00006917
GO:0042742 defense response to bacterium P
IEP
AthAt4g11150
GO:0048477 oogenesis P
IMP
CelWBGene00006917
GO:0050801 ion homeostasis P
RCA
SceS000005859
GO:0070265 necrotic cell death P
IMP
CelWBGene00006917

Back to the top

Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPAC11E3.07
(O13687)		 YOR332W
(S000005859)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000221 vacuolar proton-transporting V-type ATPase, V1
domain		 C
ISS
SpoSPAC11E3.07
TAS
SceS000005859
GO:0000329 fungal-type vacuole membrane C
IDA
SpoSPAC11E3.07
TAS
SceS000005859
GO:0005524 ATP binding F
IC
SpoSPAC11E3.07
GO:0046961 proton-transporting ATPase activity, rotational
mechanism		 F
ISS
SpoSPAC11E3.07
TAS
SceS000005859
GO:0006811 ion transport P
RCA
SceS000005859
GO:0007035 vacuolar acidification P
ISS
SpoSPAC11E3.07
TAS
SceS000005859
GO:0009117 nucleotide metabolic process P
RCA
SceS000005859
GO:0015991 ATP hydrolysis coupled proton transport P
IC
SpoSPAC11E3.07
GO:0050801 ion homeostasis P
RCA
SceS000005859

Back to the top
YOGY Home YOGY Help

Search for gene by ID or name:

Query species:

Include wild-cards:   

Search for GO info:  

GO info in one table:

s.khadayate@ucl.ac.uk