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Search term: YOR347C

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name PYK2
SGD link S000005874
Alternative ID YOR347C
Description Pyruvate kinase that appears to be modulated by phosphorylation; PYK2 transcription is repressed by glucose, and Pyk2p may be active under low glycolytic flux
Synonyms YOR347C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG2323 ACDHYPE

KOGs classification KOGs description
METABOLISM Pyruvate kinase

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At1g32440 GI:15223199
Arabidopsis thaliana (Ath) At2g36580 GI:15227999
Arabidopsis thaliana (Ath) At3g04050 GI:15229214
Arabidopsis thaliana (Ath) At3g22960 GI:15228915
Arabidopsis thaliana (Ath) At3g25960 GI:15230952
Arabidopsis thaliana (Ath) At3g49160 GI:15229099
Arabidopsis thaliana (Ath) At3g52990 GI:11260409
Arabidopsis thaliana (Ath) At3g55650 GI:15228164
Arabidopsis thaliana (Ath) At3g55810 GI:15228196
Arabidopsis thaliana (Ath) At4g26390 GI:15236190
Arabidopsis thaliana (Ath) At5g08570 GI:15242313
Arabidopsis thaliana (Ath) At5g52920 GI:15237303
Arabidopsis thaliana (Ath) At5g56350 GI:15241190
Arabidopsis thaliana (Ath) At5g63680 GI:15242863
Caenorhabditis elegans (Cel) CE15898
(WBGene00009126)		 GI:17506829 O17835
Caenorhabditis elegans (Cel) CE15899 GI:17506831 O17835
Caenorhabditis elegans (Cel) CE24731
(WBGene00014001)		 GI:17544584 Q23539
Drosophila melanogaster (Dme) 7293984 GI:7293984
Drosophila melanogaster (Dme) 7295904 GI:20129185
Drosophila melanogaster (Dme) 7296477 GI:7296477
Drosophila melanogaster (Dme) 7299922 GI:7299922
Drosophila melanogaster (Dme) 7300837 GI:7300837
Drosophila melanogaster (Dme) 7300838 GI:7300838
Homo sapiens (Hsa) Hs10835121
(PKLR)		 GI:10835121 P30613
Homo sapiens (Hsa) Hs17461113 GI:17461113
Homo sapiens (Hsa) Hs18543831 GI:18543831
Homo sapiens (Hsa) Hs22057312 GI:22057312
Homo sapiens (Hsa) Hs4505839 GI:4505839
Saccharomyces cerevisiae (Sce) YAL038w
(S000000036)		 GI:6319279 P00549
Saccharomyces cerevisiae (Sce) YOR347c
(S000005874)		 GI:6324923 P52489
Schizosaccharomyces pombe (Spo) SPAC4H3.10c GI:19115258 Q10208
Encephalitozoon cuniculi (Ecu) ECU09g0640 GI:19173186


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0001950 plasma membrane enriched fraction C
IDA
SceS000000036
GO:0005575 cellular_component C
ND
AthAt5g56350
At4g26390
At5g08570
At3g04050
At3g49160
GO:0005739 mitochondrion C
IDA
AthAt5g52920
At3g55650
SceS000005874
GO:0005829 cytosol C
IDA
SpoSPAC4H3.10c
TAS
SceS000000036
S000005874
GO:0005886 plasma membrane C
IDA
AthAt2g36580
At5g63680
GO:0009507 chloroplast C
IDA
AthAt3g22960
At1g32440
At5g52920
GO:0009570 chloroplast stroma C
IDA
AthAt3g22960
At5g52920
At1g32440
GO:0016020 membrane C
IDA
AthAt3g52990
GO:0004743 pyruvate kinase activity F
IDA
AthAt1g32440
At5g52920
At3g22960
SceS000000036
IMP
SceS000005874
S000000036
ISS
AthAt3g55810
At4g26390
At3g04050
At5g52920
At5g08570
At3g55650
At2g36580
At3g49160
At1g32440
At3g22960
At3g52990
At5g56350
At3g25960
At5g63680
SpoSPAC4H3.10c
GO:0006066 alcohol metabolic process P
RCA
SceS000000036
GO:0006082 organic acid metabolic process P
RCA
SceS000000036
GO:0006090 pyruvate metabolic process P
IMP
SceS000000036
S000005874
ISS
SpoSPAC4H3.10c
GO:0006096 glycolysis P
IMP
SceS000000036
ISS
AthAt1g32440
At5g08570
At3g55810
At4g26390
At5g56350
At3g55650
At5g52920
At3g22960
At2g36580
At3g04050
At3g52990
At3g49160
At3g25960
At5g63680
SpoSPAC4H3.10c
GO:0006417 regulation of translation P
RCA
SceS000000036
GO:0006629 lipid metabolic process P
IGI
AthAt3g22960
At5g52920
GO:0006633 fatty acid biosynthetic process P
IGI
AthAt1g32440
IMP
AthAt5g52920
GO:0006807 nitrogen compound metabolic process P
RCA
SceS000000036
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00009126
GO:0046686 response to cadmium ion P
IEP
AthAt3g22960
At5g52920
At3g52990
At5g63680
GO:0048316 seed development P
IMP
AthAt5g52920
GO:0070317 negative regulation of G0 to G1
transition		 P
IMP
SpoSPAC4H3.10c

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
37286

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) PKLR GI:10835121 P30613
Pan troglodytes (Ptr) PKLR GI:114560005
Canis familiaris (Cfa) PKLR GI:73961595
Mus musculus (Mmu) Pklr
(MGI:97604)		 GI:8567390 A7MCU9
Rattus norvegicus (Rno) Pklr
(RGD:3336)		 GI:40363265 34290
Saccharomyces cerevisiae (Sce) PYK2
(S000005874)		 GI:6324923 P52489
Arabidopsis thaliana (Ath) AT3G04050 GI:15229214
Arabidopsis thaliana (Ath) AT3G55650 GI:15228164
Arabidopsis thaliana (Ath) AT3G25960 GI:15230952
Arabidopsis thaliana (Ath) AT3G55810 GI:15228196


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
AthAt3g04050
GO:0005625 soluble fraction C
ISO
MmuMGI:97604
GO:0005739 mitochondrion C
IDA
AthAt3g55650
SceS000005874
GO:0005829 cytosol C
ISO
MmuMGI:97604
TAS
SceS000005874
GO:0004743 pyruvate kinase activity F
IDA
MmuMGI:97604
IMP
SceS000005874
ISO
MmuMGI:97604
ISS
AthAt3g55810
At3g04050
At3g55650
At3g25960
GO:0005975 carbohydrate metabolic process P
ISO
MmuMGI:97604
GO:0006090 pyruvate metabolic process P
IMP
SceS000005874
GO:0006096 glycolysis P
ISO
MmuMGI:97604
ISS
AthAt3g55810
At3g55650
At3g04050
At3g25960
GO:0006754 ATP biosynthetic process P
ISO
MmuMGI:97604
GO:0009408 response to heat P
ISO
MmuMGI:97604
GO:0010226 response to lithium ion P
ISO
MmuMGI:97604
GO:0016310 phosphorylation P
IDA
MmuMGI:97604
GO:0032869 cellular response to insulin stimulus P
ISO
MmuMGI:97604
GO:0033198 response to ATP P
ISO
MmuMGI:97604
GO:0042866 pyruvate biosynthetic process P
ISO
MmuMGI:97604
GO:0051591 response to cAMP P
ISO
MmuMGI:97604
GO:0051707 response to other organism P
IMP
MmuMGI:97604

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_160

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga7159 ENSANGP00000021580
Ashbya gossypii (Ago) ago2109 ADR368W
Arabidopsis thaliana (Ath) ath3398 At1g32440.1
Arabidopsis thaliana (Ath) ath12441 At3g04050.1
Arabidopsis thaliana (Ath) ath14923 At3g25960.1
Arabidopsis thaliana (Ath) ath16950 At3g55650.1
Arabidopsis thaliana (Ath) ath16968 At3g55810.1
Arabidopsis thaliana (Ath) ath20633 At4g26390.1
Arabidopsis thaliana (Ath) ath23082 At5g08570.1
Arabidopsis thaliana (Ath) ath27249 At5g52920.1
Arabidopsis thaliana (Ath) ath27645 At5g56350.1
Arabidopsis thaliana (Ath) ath28490 At5g63680.1
Caenorhabditis elegans (Cel) cel7281 F25H5.3a
(CE15898;
WBGene00009126)
Caenorhabditis elegans (Cel) cel7282 F25H5.3b
(CE15899)
Caenorhabditis elegans (Cel) cel7283 F25H5.3c
(CE36135)
Caenorhabditis elegans (Cel) cel7284 F25H5.3d
(CE37832)
Caenorhabditis elegans (Cel) cel22011 ZK593.1
(CE24731;
WBGene00014001)
Candida glabrata (Cgl) cgl1185 CAGL0E05610g
Candida glabrata (Cgl) cgl5179 CAGL0M12034g
Cryptococcus neoformans (Cne) cne5423 179.m00276
Cryptococcus neoformans (Cne) cne5424 179.m00277
Dictyostelium discoideum (Ddi) ddi12315 DDB0231421
Debaryomyces hansenii (Dha) dha2835 DEHA0D12122g
Drosophila melanogaster (Dme) dme13830 CG7069-PA
(FBgn0038952)
Drosophila melanogaster (Dme) dme13829 CG7070-PA
(FBgn0003178)
Drosophila melanogaster (Dme) dme13828 CG7070-PB
(FBgn0003178)
Drosophila melanogaster (Dme) dme12631 CG7362-PA
(FBgn0038258)
Danio rerio (Dre) dre26926 ENSDARP00000017190
(zgc:92037)		 Q6DG54
Escherichia coli (Eco) eco1634 16129632
Escherichia coli (Eco) eco1810 16129807
Encephalitozoon cuniculi (Ecu) ecu1337 19173186
Takifugu rubripes (Fru) fru26573 SINFRUP00000128238
Takifugu rubripes (Fru) fru1841 SINFRUP00000141035
Gallus gallus (Gga) gga3610 ENSGALP00000003096
(PKM2)		 P00548
Homo sapiens (Hsa) hsa2212 ENSP00000271946
(PKLR)		 B1AVT2
Homo sapiens (Hsa) hsa10868 ENSP00000320171
(PKM2)		 P14618-2
Homo sapiens (Hsa) hsa10869 ENSP00000334983
(PKM2)		 P14618-1
Homo sapiens (Hsa) hsa2211 ENSP00000339933
(PKLR)		 P30613-1
Kluyveromyces lactis (Kla) kla5122 KLLA0F23397g
Mus musculus (Mmu) mmu27751 ENSMUSP00000034834
(MGI:97591)		 P52480-1
Mus musculus (Mmu) mmu31241 ENSMUSP00000035417
(MGI:97604)		 P53657
Neurospora crassa (Ncr) ncr5905 NCU06075.2
Oryza sativa (Osa) osa5444 2372.m00188
Oryza sativa (Osa) osa9535 2733.m00145
Oryza sativa (Osa) osa25037 3836.m00134
Oryza sativa (Osa) osa45362 5387.m00157
Oryza sativa (Osa) osa47706 5649.m00169
Oryza sativa (Osa) osa47101 5770.m00097
Plasmodium falciparum (Pfa) pfa581 PF10_0363
Plasmodium falciparum (Pfa) pfa3154 PFF1300w
Rattus norvegicus (Rno) rno28744 ENSRNOP00000015331
(RGD:3337)		 P11980-2
Rattus norvegicus (Rno) rno28743 ENSRNOP00000015398
(RGD:3337)		 P11980-1
Rattus norvegicus (Rno) rno16404 ENSRNOP00000027700
(RGD:3336)		 P12928-1
Saccharomyces cerevisiae (Sce) sce46 YAL038W
(S000000036)
Saccharomyces cerevisiae (Sce) sce6102 YOR347C
(S000005874)
Schizosaccharomyces pombe (Spo) spo2931 SPAC4H3.10c Q10208
Yarrowia lipolytica (Yli) yli5731 YALI0F09185g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0001950 plasma membrane enriched fraction C
IDA
SceS000000036
GO:0005575 cellular_component C
ND
AthAt5g56350
At4g26390
At5g08570
At3g04050
GO:0005625 soluble fraction C
ISO
MmuMGI:97604
MGI:97591
GO:0005739 mitochondrion C
IDA
AthAt5g52920
At3g55650
MmuMGI:97591
SceS000005874
GO:0005811 lipid particle C
IDA
DmeFBgn0003178
GO:0005829 cytosol C
IDA
DmeFBgn0003178
SpoSPAC4H3.10c
ISO
MmuMGI:97604
ISS
PfaPF10_0363
TAS
SceS000000036
S000005874
GO:0005886 plasma membrane C
IDA
AthAt5g63680
GO:0009507 chloroplast C
IDA
AthAt1g32440
At5g52920
GO:0009570 chloroplast stroma C
IDA
AthAt5g52920
At1g32440
GO:0019861 flagellum C
IDA
MmuMGI:97591
GO:0020011 apicoplast C
IDA
PfaPF10_0363
GO:0004743 pyruvate kinase activity F
IDA
AthAt1g32440
At5g52920
MmuMGI:97591
MGI:97604
SceS000000036
IMP
DmeFBgn0003178
SceS000005874
S000000036
ISO
MmuMGI:97604
MGI:97591
ISS
AthAt3g55810
At4g26390
At3g04050
At5g52920
At5g08570
At3g55650
At1g32440
At5g56350
At3g25960
At5g63680
DmeFBgn0038258
FBgn0003178
FBgn0038952
SpoSPAC4H3.10c
NAS
DmeFBgn0003178
GO:0005515 protein binding F
IPI
MmuMGI:97591
GO:0043531 ADP binding F
ISO
MmuMGI:97591
GO:0001889 liver development P
ISO
MmuMGI:97591
GO:0005975 carbohydrate metabolic process P
ISO
MmuMGI:97604
GO:0006006 glucose metabolic process P
ISO
MmuMGI:97591
GO:0006066 alcohol metabolic process P
RCA
SceS000000036
GO:0006082 organic acid metabolic process P
RCA
SceS000000036
GO:0006090 pyruvate metabolic process P
IMP
SceS000000036
S000005874
ISS
SpoSPAC4H3.10c
GO:0006096 glycolysis P
IDA
MmuMGI:97591
IMP
SceS000000036
ISO
MmuMGI:97604
MGI:97591
ISS
AthAt1g32440
At5g08570
At3g55810
At4g26390
At5g56350
At3g55650
At5g52920
At3g04050
At3g25960
At5g63680
SpoSPAC4H3.10c
NAS
DmeFBgn0003178
GO:0006417 regulation of translation P
RCA
SceS000000036
GO:0006629 lipid metabolic process P
IGI
AthAt5g52920
GO:0006633 fatty acid biosynthetic process P
IGI
AthAt1g32440
IMP
AthAt5g52920
GO:0006754 ATP biosynthetic process P
ISO
MmuMGI:97604
MGI:97591
GO:0006807 nitrogen compound metabolic process P
RCA
SceS000000036
GO:0006911 phagocytosis, engulfment P
IMP
DmeFBgn0038258
GO:0009408 response to heat P
ISO
MmuMGI:97604
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00009126
GO:0010226 response to lithium ion P
ISO
MmuMGI:97604
GO:0016310 phosphorylation P
IDA
MmuMGI:97591
MGI:97604
ISS
DmeFBgn0003178
GO:0031100 organ regeneration P
ISO
MmuMGI:97591
GO:0032869 cellular response to insulin stimulus P
ISO
MmuMGI:97604
GO:0033198 response to ATP P
ISO
MmuMGI:97604
GO:0042866 pyruvate biosynthetic process P
ISO
MmuMGI:97604
MGI:97591
GO:0043403 skeletal muscle tissue regeneration P
ISO
MmuMGI:97591
GO:0046686 response to cadmium ion P
IEP
AthAt5g52920
At5g63680
GO:0048316 seed development P
IMP
AthAt5g52920
GO:0051591 response to cAMP P
ISO
MmuMGI:97604
GO:0051707 response to other organism P
IMP
MmuMGI:97604
GO:0070317 negative regulation of G0 to G1
transition		 P
IMP
SpoSPAC4H3.10c

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPAC4H3.10c
(Q10208)		 YOR347C
(S000005874)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005739 mitochondrion C
IDA
SceS000005874
GO:0005829 cytosol C
IDA
SpoSPAC4H3.10c
TAS
SceS000005874
GO:0004743 pyruvate kinase activity F
IMP
SceS000005874
ISS
SpoSPAC4H3.10c
GO:0006090 pyruvate metabolic process P
IMP
SceS000005874
ISS
SpoSPAC4H3.10c
GO:0006096 glycolysis P
ISS
SpoSPAC4H3.10c
GO:0070317 negative regulation of G0 to G1
transition		 P
IMP
SpoSPAC4H3.10c

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