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Search term: YOR360C

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name PDE2
SGD link S000005887
Alternative ID YOR360C
Description High-affinity cyclic AMP phosphodiesterase, component of the cAMP-dependent protein kinase signaling system, protects the cell from extracellular cAMP, contains readthrough motif surrounding termination codon
Synonyms YOR360C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG3689 -CDHY--

KOGs classification KOGs description
CELLULAR PROCESSES AND SIGNALING Cyclic nucleotide phosphodiesterase

Species KOG link NCBI link UniProt link
Caenorhabditis elegans (Cel) CE01047 GI:17554528
Caenorhabditis elegans (Cel) CE02038
(WBGene00020114)		 GI:17535659 Q22000
Caenorhabditis elegans (Cel) CE04134 GI:17505809
Caenorhabditis elegans (Cel) CE28641 GI:17535661 Q22000
Drosophila melanogaster (Dme) 7290408 GI:17933546
Drosophila melanogaster (Dme) 7292811 GI:7292811
Drosophila melanogaster (Dme) 7292812 GI:7292812
Drosophila melanogaster (Dme) 7298454 GI:7298454
Homo sapiens (Hsa) Hs15812212 GI:15812212
Homo sapiens (Hsa) Hs15812214 GI:15812214
Homo sapiens (Hsa) Hs15812216 GI:15812216
Homo sapiens (Hsa) Hs19923440 GI:19923440
Homo sapiens (Hsa) Hs20538967 GI:20538967
Homo sapiens (Hsa) Hs21361308 GI:940231 P51160
Homo sapiens (Hsa) Hs22050327 GI:22050327
Homo sapiens (Hsa) Hs4505657
(PDE2A)		 GI:4505657 O00408
Homo sapiens (Hsa) Hs4505663 GI:4505663
Homo sapiens (Hsa) Hs4505665 GI:4505665
Homo sapiens (Hsa) Hs4505667 GI:4505667
Homo sapiens (Hsa) Hs4505669 GI:4505669
Homo sapiens (Hsa) Hs4505675
(PDE9A)		 GI:4505675 O76083
Homo sapiens (Hsa) Hs4585864 GI:4585864
Homo sapiens (Hsa) Hs5453862 GI:5453862 Q8WUQ3
Homo sapiens (Hsa) Hs5453864 GI:5453864
Homo sapiens (Hsa) Hs5729972 GI:5729972 Q9ULW9
Homo sapiens (Hsa) Hs9506959
(PDE7B)		 GI:9506959 Q9NP56
Homo sapiens (Hsa) HsM5453866 GI:5453866
Saccharomyces cerevisiae (Sce) YOR360c
(S000005887)		 GI:6324936 P06776


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SceS000005887
GO:0005737 cytoplasm C
IDA
SceS000005887
GO:0005829 cytosol C
IDA
HsaPDE9A
GO:0045202 synapse C
IDA
CelWBGene00020114
GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase
activity		 F
TAS
HsaPDE9A
GO:0004115 3',5'-cyclic-AMP phosphodiesterase
activity		 F
IDA
SceS000005887
TAS
HsaPDE7B
GO:0004118 cGMP-stimulated cyclic-nucleotide
phosphodiesterase activity		 F
TAS
HsaPDE2A
GO:0005515 protein binding F
IPI
HsaPDE2A
PDE9A
GO:0006414 translational elongation P
RCA
SceS000005887
GO:0007268 synaptic transmission P
TAS
HsaPDE7B
GO:0007568 aging P
RCA
SceS000005887
GO:0019932 second-messenger-mediated signaling P
RCA
SceS000005887
GO:0019933 cAMP-mediated signaling P
IMP
SceS000005887
GO:0030431 sleep P
IMP
CelWBGene00020114
GO:0040013 negative regulation of locomotion P
IMP
CelWBGene00020114
GO:0043951 negative regulation of cAMP-mediated
signaling		 P
IGI
CelWBGene00020114

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
40376

Species Gene ID NCBI link UniProt link
Saccharomyces cerevisiae (Sce) PDE2
(S000005887)		 GI:6324936 P06776
Kluyveromyces lactis (Kla) KLLA0A03619g GI:50302449
Eremothecium gossypii (Ego) AGOS_ADR395C GI:45188267


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SceS000005887
GO:0005737 cytoplasm C
IDA
SceS000005887
GO:0004115 3',5'-cyclic-AMP phosphodiesterase
activity		 F
IDA
SceS000005887
GO:0006414 translational elongation P
RCA
SceS000005887
GO:0007568 aging P
RCA
SceS000005887
GO:0019932 second-messenger-mediated signaling P
RCA
SceS000005887
GO:0019933 cAMP-mediated signaling P
IMP
SceS000005887

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_11652

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Ashbya gossypii (Ago) ago2135 ADR395C
Candida glabrata (Cgl) cgl3948 CAGL0K09944g
Cryptococcus neoformans (Cne) cne4684 186.m03536
Debaryomyces hansenii (Dha) dha2683 DEHA0D08778g
Takifugu rubripes (Fru) fru24371 SINFRUP00000140137
Kluyveromyces lactis (Kla) kla156 KLLA0A03619g
Neurospora crassa (Ncr) ncr464 NCU00478.2
Saccharomyces cerevisiae (Sce) sce6115 YOR360C
(S000005887)
Yarrowia lipolytica (Yli) yli264 YALI0A08041g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SceS000005887
GO:0005737 cytoplasm C
IDA
SceS000005887
GO:0004115 3',5'-cyclic-AMP phosphodiesterase
activity		 F
IDA
SceS000005887
GO:0006414 translational elongation P
RCA
SceS000005887
GO:0007568 aging P
RCA
SceS000005887
GO:0019932 second-messenger-mediated signaling P
RCA
SceS000005887
GO:0019933 cAMP-mediated signaling P
IMP
SceS000005887

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