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Search term: YOR368W


Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name RAD17
SGD link S000005895
Alternative ID YOR368W
Description Checkpoint protein, involved in the activation of the DNA damage and meiotic pachytene checkpoints; with Mec3p and Ddc1p, forms a clamp that is loaded onto partial duplex DNA; homolog of human and S. pombe Rad1 and U. maydis Rec1 proteins
Synonyms YOR368W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG3194 -C-HYP-

KOGs classification KOGs description
CELLULAR PROCESSES AND SIGNALINGINFORMATION STORAGE AND PROCESSING Checkpoint 9-1-1 complex, RAD1 component

Species KOG link NCBI link UniProt link
Caenorhabditis elegans (Cel) CE29376
(WBGene00003417)
GI:17555854 Q9U2I2
Homo sapiens (Hsa) Hs4506385
(RAD1)
GI:4506385 O60671
Homo sapiens (Hsa) Hs20549051 GI:20549051
Homo sapiens (Hsa) Hs19718799 GI:19718799
Saccharomyces cerevisiae (Sce) YOR368w
(S000005895)
GI:6324944 P48581
Schizosaccharomyces pombe (Spo) SPAC1952.07 GI:19115721 P22193


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IC
CelWBGene00003417
HsaRAD1
IDA
SpoSPAC1952.07
IPI
SceS000005895
GO:0005829 cytosol C
IDA
SpoSPAC1952.07
GO:0030896 checkpoint clamp complex C
IDA
SceS000005895
SpoSPAC1952.07
GO:0003684 damaged DNA binding F
ISS
CelWBGene00003417
NAS
HsaRAD1
GO:0003690 double-stranded DNA binding F
IDA
SceS000005895
GO:0005515 protein binding F
IPI
HsaRAD1
SpoSPAC1952.07
GO:0008408 3'-5' exonuclease activity F
IDA
HsaRAD1
GO:0000075 cell cycle checkpoint P
NAS
HsaRAD1
GO:0000076 DNA replication checkpoint P
IMP
SpoSPAC1952.07
GO:0000077 DNA damage checkpoint P
IMP
CelWBGene00003417
SceS000005895
SpoSPAC1952.07
TAS
HsaRAD1
GO:0000723 telomere maintenance P
IMP
CelWBGene00003417
GO:0006260 DNA replication P
EXP
HsaRAD1
RCA
SceS000005895
GO:0006281 DNA repair P
IMP
SpoSPAC1952.07
GO:0006289 nucleotide-excision repair P
IMP
CelWBGene00003417
GO:0006302 double-strand break repair P
IMP
SceS000005895
GO:0006974 response to DNA damage stimulus P
IMP
CelWBGene00003417
TAS
HsaRAD1
GO:0007004 telomere maintenance via telomerase P
IMP
CelWBGene00003417
GO:0007128 meiotic prophase I P
TAS
HsaRAD1
GO:0007131 reciprocal meiotic recombination P
IMP
SceS000005895
GO:0007346 regulation of mitotic cell cycle P
NAS
SpoSPAC1952.07
GO:0008630 DNA damage response, signal transduction resulting
in induction of apoptosis
P
IMP
CelWBGene00003417
GO:0031573 intra-S DNA damage checkpoint P
IMP
SpoSPAC1952.07
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00003417
GO:0045132 meiotic chromosome segregation P
IMP
CelWBGene00003417
GO:0051052 regulation of DNA metabolic process P
RCA
SceS000005895
GO:0051726 regulation of cell cycle P
RCA
SceS000005895

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
40378

Species Gene ID NCBI link UniProt link
Saccharomyces cerevisiae (Sce) RAD17
(S000005895)
GI:6324944 P48581
Kluyveromyces lactis (Kla) KLLA0F00330g GI:50310149
Eremothecium gossypii (Ego) AGOS_ADR411W GI:45188283


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IPI
SceS000005895
GO:0030896 checkpoint clamp complex C
IDA
SceS000005895
GO:0003690 double-stranded DNA binding F
IDA
SceS000005895
GO:0000077 DNA damage checkpoint P
IMP
SceS000005895
GO:0006260 DNA replication P
RCA
SceS000005895
GO:0006302 double-strand break repair P
IMP
SceS000005895
GO:0007131 reciprocal meiotic recombination P
IMP
SceS000005895
GO:0051052 regulation of DNA metabolic process P
RCA
SceS000005895
GO:0051726 regulation of cell cycle P
RCA
SceS000005895

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_20762

Species OrthoMCL
sequence
Model organism
protein page
UniProt link
Ashbya gossypii (Ago) ago2151 ADR411W
Candida glabrata (Cgl) cgl3305 CAGL0J07216g
Debaryomyces hansenii (Dha) dha4659 DEHA0F06116g
Kluyveromyces lactis (Kla) kla4093 KLLA0F00330g
Saccharomyces cerevisiae (Sce) sce6123 YOR368W
(S000005895)
Yarrowia lipolytica (Yli) yli5604 YALI0F06204g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IPI
SceS000005895
GO:0030896 checkpoint clamp complex C
IDA
SceS000005895
GO:0003690 double-stranded DNA binding F
IDA
SceS000005895
GO:0000077 DNA damage checkpoint P
IMP
SceS000005895
GO:0006260 DNA replication P
RCA
SceS000005895
GO:0006302 double-strand break repair P
IMP
SceS000005895
GO:0007131 reciprocal meiotic recombination P
IMP
SceS000005895
GO:0051052 regulation of DNA metabolic process P
RCA
SceS000005895
GO:0051726 regulation of cell cycle P
RCA
SceS000005895

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Curated yeast ortholog results:

S. pombe
systematic ID
S. cerevisiae
systematic ID
SPAC1952.07
(P22193)
YOR368W
(S000005895)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SpoSPAC1952.07
IPI
SceS000005895
GO:0005829 cytosol C
IDA
SpoSPAC1952.07
GO:0030896 checkpoint clamp complex C
IDA
SceS000005895
SpoSPAC1952.07
GO:0003690 double-stranded DNA binding F
IDA
SceS000005895
GO:0005515 protein binding F
IPI
SpoSPAC1952.07
GO:0000076 DNA replication checkpoint P
IMP
SpoSPAC1952.07
GO:0000077 DNA damage checkpoint P
IMP
SceS000005895
SpoSPAC1952.07
GO:0006260 DNA replication P
RCA
SceS000005895
GO:0006281 DNA repair P
IMP
SpoSPAC1952.07
GO:0006302 double-strand break repair P
IMP
SceS000005895
GO:0007131 reciprocal meiotic recombination P
IMP
SceS000005895
GO:0007346 regulation of mitotic cell cycle P
NAS
SpoSPAC1952.07
GO:0031573 intra-S DNA damage checkpoint P
IMP
SpoSPAC1952.07
GO:0051052 regulation of DNA metabolic process P
RCA
SceS000005895
GO:0051726 regulation of cell cycle P
RCA
SceS000005895

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