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Search term: YPL022W


Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name RAD1
SGD link S000005943
Alternative ID YPL022W
Description Single-stranded DNA endonuclease (with Rad10p), cleaves single-stranded DNA during nucleotide excision repair and double-strand break repair; subunit of Nucleotide Excision Repair Factor 1 (NEF1); homolog of human XPF protein
Synonyms YPL022W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:


KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG0442 ACDHYPE

KOGs classification KOGs description
INFORMATION STORAGE AND PROCESSING Structure-specific endonuclease ERCC1-XPF, catalytic component XPF/ERCC4

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At5g41150 GI:15237571
Caenorhabditis elegans (Cel) CE24855
(WBGene00008140)
GI:17532461 Q18671
Drosophila melanogaster (Dme) 7290484
(FBgn0002707)
GI:17933560
Homo sapiens (Hsa) Hs20543290 GI:20543290
Homo sapiens (Hsa) Hs4885217
(ERCC4)
GI:4885217 Q92889
Saccharomyces cerevisiae (Sce) YPL022w
(S000005943)
GI:6325235 P06777
Schizosaccharomyces pombe (Spo) SPCC970.01 GI:19075355 P36617
Encephalitozoon cuniculi (Ecu) ECU08g0760 GI:19173402 Q8SRC6
Arabidopsis thaliana (Ath) At5g41150 GI:15237571
Caenorhabditis elegans (Cel) CE24855
(WBGene00008140)
GI:17532461 Q18671
Drosophila melanogaster (Dme) 7290484
(FBgn0002707)
GI:17933560
Homo sapiens (Hsa) Hs20543290 GI:20543290
Homo sapiens (Hsa) Hs4885217
(ERCC4)
GI:4885217 Q92889
Saccharomyces cerevisiae (Sce) YPL022w
(S000005943)
GI:6325235 P06777
Schizosaccharomyces pombe (Spo) SPCC970.01 GI:19075355 P36617
Encephalitozoon cuniculi (Ecu) ECU08g0760 GI:19173402 Q8SRC6
Arabidopsis thaliana (Ath) At5g41150 GI:15237571
Caenorhabditis elegans (Cel) CE24855
(WBGene00008140)
GI:17532461 Q18671
Drosophila melanogaster (Dme) 7290484
(FBgn0002707)
GI:17933560
Homo sapiens (Hsa) Hs20543290 GI:20543290
Homo sapiens (Hsa) Hs4885217
(ERCC4)
GI:4885217 Q92889
Saccharomyces cerevisiae (Sce) YPL022w
(S000005943)
GI:6325235 P06777
Schizosaccharomyces pombe (Spo) SPCC970.01 GI:19075355 P36617
Encephalitozoon cuniculi (Ecu) ECU08g0760 GI:19173402 Q8SRC6


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000109 nucleotide-excision repair complex C
IDA
HsaERCC4
ISS
SpoSPCC970.01
GO:0000110 nucleotide-excision repair factor 1
complex
C
IPI
SceS000005943
GO:0000781 chromosome, telomeric region C
IDA
HsaERCC4
GO:0000784 nuclear chromosome, telomeric region C
IDA
HsaERCC4
GO:0005634 nucleus C
IC
SpoSPCC970.01
IDA
HsaERCC4
SceS000005943
SpoSPCC970.01
NAS
DmeFBgn0002707
GO:0005654 nucleoplasm C
EXP
HsaERCC4
GO:0005816 spindle pole body C
IDA
SpoSPCC970.01
GO:0043234 protein complex C
IDA
DmeFBgn0002707
GO:0000014 single-stranded DNA specific endodeoxyribonuclease
activity
F
IDA
SceS000005943
IMP
AthAt5g41150
ISS
SpoSPCC970.01
GO:0003677 DNA binding F
ISS
SpoSPCC970.01
GO:0003684 damaged DNA binding F
IMP
HsaERCC4
GO:0003697 single-stranded DNA binding F
IDA
HsaERCC4
SceS000005943
GO:0004520 endodeoxyribonuclease activity F
IDA
HsaERCC4
ERCC4
ISS
DmeFBgn0002707
GO:0005515 protein binding F
IPI
DmeFBgn0002707
HsaERCC4
GO:0008022 protein C-terminus binding F
IPI
HsaERCC4
GO:0008821 crossover junction endodeoxyribonuclease
activity
F
RCA
SceS000005943
GO:0016889 endodeoxyribonuclease activity, producing
3'-phosphomonoesters
F
RCA
SceS000005943
GO:0016894 endonuclease activity, active with either ribo- or
deoxyribonucleic acids and producing
3'-phosphomonoesters
F
RCA
SceS000005943
GO:0043566 structure-specific DNA binding F
IDA
HsaERCC4
GO:0046982 protein heterodimerization activity F
IPI
DmeFBgn0002707
SpoSPCC970.01
GO:0047485 protein N-terminus binding F
IPI
HsaERCC4
GO:0000710 meiotic mismatch repair P
IMP
SceS000005943
GO:0000712 resolution of meiotic recombination
intermediates
P
IMP
DmeFBgn0002707
TAS
DmeFBgn0002707
GO:0000718 nucleotide-excision repair, DNA damage
removal
P
EXP
HsaERCC4
GO:0000723 telomere maintenance P
IMP
HsaERCC4
GO:0000724 double-strand break repair via homologous
recombination
P
IMP
AthAt5g41150
HsaERCC4
GO:0000735 removal of nonhomologous ends P
IMP
SceS000005943
GO:0000736 double-strand break repair via single-strand
annealing, removal of nonhomologous
ends
P
IMP
SceS000005943
GO:0006281 DNA repair P
IEP
AthAt5g41150
IMP
HsaERCC4
RCA
SceS000005943
GO:0006289 nucleotide-excision repair P
IDA
HsaERCC4
IGI
SpoSPCC970.01
IMP
AthAt5g41150
DmeFBgn0002707
HsaERCC4
ISS
DmeFBgn0002707
NAS
DmeFBgn0002707
TAS
DmeFBgn0002707
GO:0006295 nucleotide-excision repair, DNA incision, 3'-to
lesion
P
IMP
HsaERCC4
GO:0006296 nucleotide-excision repair, DNA incision, 5'-to
lesion
P
IDA
SceS000005943
IMP
HsaERCC4
TAS
SpoSPCC970.01
GO:0006298 mismatch repair P
IMP
DmeFBgn0002707
NAS
DmeFBgn0002707
GO:0006302 double-strand break repair P
TAS
DmeFBgn0002707
GO:0006310 DNA recombination P
NAS
DmeFBgn0002707
TAS
DmeFBgn0002707
GO:0006311 meiotic gene conversion P
IMP
SpoSPCC970.01
GO:0006312 mitotic recombination P
IMP
SceS000005943
GO:0006974 response to DNA damage stimulus P
IMP
CelWBGene00008140
RCA
SceS000005943
GO:0006979 response to oxidative stress P
IMP
AthAt5g41150
GO:0007131 reciprocal meiotic recombination P
IMP
DmeFBgn0002707
RCA
SceS000005943
GO:0007534 gene conversion at mating-type
locus
P
IMP
SpoSPCC970.01
GO:0009314 response to radiation P
IEP
AthAt5g41150
GO:0009411 response to UV P
IMP
HsaERCC4
GO:0009792 embryo development ending in birth or egg
hatching
P
IMP
CelWBGene00008140
GO:0010834 telomere maintenance via telomere
shortening
P
IMP
HsaERCC4
GO:0016321 female meiosis chromosome segregation P
IMP
DmeFBgn0002707
GO:0032205 negative regulation of telomere
maintenance
P
IMP
HsaERCC4
GO:0033683 nucleotide-excision repair, DNA
incision
P
IDA
HsaERCC4
GO:0045132 meiotic chromosome segregation P
IMP
DmeFBgn0002707
GO:0051049 regulation of transport P
RCA
SceS000005943
GO:0051321 meiotic cell cycle P
RCA
SceS000005943

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
3836

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) ERCC4 GI:4885217 Q92889
Pan troglodytes (Ptr) ERCC4 GI:114661075
Canis familiaris (Cfa) ERCC4 GI:73959081
Mus musculus (Mmu) Ercc4
(MGI:1354163)
GI:7657064 Q3UEU6
Rattus norvegicus (Rno) Ercc4 GI:109487701
Gallus gallus (Gga) ERCC4 GI:118097672
Drosophila melanogaster (Dme) mei-9
(FBgn0002707)
GI:17933560
Anopheles gambiae (Aga) AgaP_AGAP002805 GI:158290513
Schizosaccharomyces pombe (Spo) rad10 GI:19075355
Saccharomyces cerevisiae (Sce) RAD1
(S000005943)
GI:6325235 P06777
Kluyveromyces lactis (Kla) KLLA0D12210g GI:50307255
Eremothecium gossypii (Ego) AGOS_AFR456C GI:45198974
Magnaporthe grisea (Mgr) MGG_02804 GI:39970675
Neurospora crassa (Ncr) NCU07440.1 GI:32414493
Arabidopsis thaliana (Ath) UVH1 GI:15237571
Oryza sativa (Osa) Os03g0100400 GI:115450089


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000109 nucleotide-excision repair complex C
IDA
HsaERCC4
ISO
MmuMGI:1354163
GO:0000110 nucleotide-excision repair factor 1
complex
C
IPI
SceS000005943
GO:0000781