YOGY Home YOGY Help

Search term: YPL028W

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name ERG10
SGD link S000005949
Alternative ID YPL028W
Description Acetyl-CoA C-acetyltransferase (acetoacetyl-CoA thiolase), cytosolic enzyme that transfers an acetyl group from one acetyl-CoA molecule to another, forming acetoacetyl-CoA; involved in the first step in mevalonate biosynthesis
Synonyms YPL028W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

Search for gene by ID or name:

Query species:

Include wild-cards:   

Search for GO info:  

GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG1390 ACDHYP-

KOGs classification KOGs description
METABOLISM Acetyl-CoA acetyltransferase

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At5g47720 GI:15238793
Arabidopsis thaliana (Ath) At5g48230 GI:8777413
Caenorhabditis elegans (Cel) CE04856
(WBGene00020164)		 GI:17535917 Q22106
Caenorhabditis elegans (Cel) CE04859
(WBGene00020166)		 GI:17535921 Q22101
Caenorhabditis elegans (Cel) CE04860 GI:17535923
Drosophila melanogaster (Dme) 7290840 GI:7290840
Drosophila melanogaster (Dme) 7292057 GI:20130421
Homo sapiens (Hsa) Hs4557237
(ACAT1)		 GI:4557237 P24752
Homo sapiens (Hsa) Hs5174389 GI:5174389
Homo sapiens (Hsa) Hs14755394 GI:14755394
Saccharomyces cerevisiae (Sce) YPL028w
(S000005949)		 GI:6325229 P41338
Schizosaccharomyces pombe (Spo) SPBC215.09c GI:19113478 Q9UQW6


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
AthAt5g47720
GO:0005739 mitochondrion C
IDA
HsaACAT1
GO:0005759 mitochondrial matrix C
EXP
HsaACAT1
GO:0005777 peroxisome C
IDA
AthAt5g48230
GO:0005829 cytosol C
IDA
SpoSPBC215.09c
ISS
SpoSPBC215.09c
TAS
SceS000005949
GO:0005886 plasma membrane C
IDA
AthAt5g48230
GO:0003985 acetyl-CoA C-acetyltransferase
activity		 F
EXP
HsaACAT1
IDA
SceS000005949
ISS
AthAt5g48230
At5g47720
SpoSPBC215.09c
GO:0005515 protein binding F
IPI
HsaACAT1
GO:0006066 alcohol metabolic process P
RCA
SceS000005949
GO:0006696 ergosterol biosynthetic process P
IMP
SceS000005949
ISS
SpoSPBC215.09c
GO:0009793 embryo development ending in seed
dormancy		 P
NAS
AthAt5g48230
GO:0010171 body morphogenesis P
IMP
CelWBGene00020166
GO:0019915 lipid storage P
IMP
CelWBGene00020164
GO:0040011 locomotion P
IMP
CelWBGene00020166
GO:0043094 cellular metabolic compound salvage P
RCA
SceS000005949

Back to the top

HomoloGene results:

HomoloGene cluster Phylogenetic pattern
6

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) ACAT1 GI:4557237 P24752
Pan troglodytes (Ptr) ACAT1 GI:114640221
Canis familiaris (Cfa) ACAT1 GI:73955189
Mus musculus (Mmu) Acat1
(MGI:87870)		 GI:21450129 Q3TQP7
Rattus norvegicus (Rno) Acat1
(RGD:2016)		 GI:8392836 36375
Gallus gallus (Gga) ACAT1 GI:118085057
Drosophila melanogaster (Dme) CG10932
(FBgn0029969)		 GI:24640423
Anopheles gambiae (Aga) AgaP_AGAP011329 GI:158287236
Caenorhabditis elegans (Cel) kat-1
(CE29990;
WBGene00002183)		 GI:25147385
Caenorhabditis elegans (Cel) T02G5.4
(CE04856;
WBGene00020164)		 GI:17535917 Q22106
Schizosaccharomyces pombe (Spo) erg10
(SPBC215.09c)		 GI:19113478 Q9UQW6
Saccharomyces cerevisiae (Sce) ERG10
(S000005949)		 GI:6325229 P41338
Kluyveromyces lactis (Kla) KLLA0D12056g GI:50307241
Eremothecium gossypii (Ego) AGOS_ADR165C GI:45188039
Magnaporthe grisea (Mgr) MGG_13499 GI:145616020
Neurospora crassa (Ncr) NCU02571.1 GI:32422653
Arabidopsis thaliana (Ath) ACAT2 GI:30695411
Oryza sativa (Osa) Os09g0252100 GI:115478180
Plasmodium falciparum (Pfa) PF14_0484 GI:124809703


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
PfaPF14_0484
GO:0005739 mitochondrion C
IDA
CelWBGene00002183
HsaACAT1
MmuMGI:87870
ISS
DmeFBgn0029969
GO:0005743 mitochondrial inner membrane C
IDA
MmuMGI:87870
GO:0005759 mitochondrial matrix C
EXP
HsaACAT1
ISO
MmuMGI:87870
GO:0005777 peroxisome C
IDA
AthACAT2
GO:0005811 lipid particle C
IDA
DmeFBgn0029969
GO:0005829 cytosol C
IDA
SpoSPBC215.09c
ISS
SpoSPBC215.09c
TAS
SceS000005949
GO:0005875 microtubule associated complex C
IDA
DmeFBgn0029969
GO:0005886 plasma membrane C
IDA
AthACAT2
GO:0003985 acetyl-CoA C-acetyltransferase
activity		 F
EXP
HsaACAT1
IDA
MmuMGI:87870
SceS000005949
ISO
MmuMGI:87870
ISS
AthACAT2
DmeFBgn0029969
PfaPF14_0484
SpoSPBC215.09c
GO:0005515 protein binding F
IPI
HsaACAT1
GO:0019899 enzyme binding F
ISO
MmuMGI:87870
GO:0042803 protein homodimerization activity F
ISO
MmuMGI:87870
GO:0050662 coenzyme binding F
ISO
MmuMGI:87870
GO:0006066 alcohol metabolic process P
RCA
SceS000005949
GO:0006090 pyruvate metabolic process P
ISS
DmeFBgn0029969
GO:0006631 fatty acid metabolic process P
ISS
PfaPF14_0484
GO:0006633 fatty acid biosynthetic process P
ISS
DmeFBgn0029969
GO:0006696 ergosterol biosynthetic process P
IMP
SceS000005949
ISS
SpoSPBC215.09c
GO:0007052 mitotic spindle organization P
IMP
DmeFBgn0029969
GO:0008152 metabolic process P
IDA
MmuMGI:87870
GO:0009793 embryo development ending in seed
dormancy		 P
NAS
AthACAT2
GO:0019915 lipid storage P
IMP
CelWBGene00020164
WBGene00002183
GO:0043094 cellular metabolic compound salvage P
RCA
SceS000005949
GO:0051260 protein homooligomerization P
ISO
MmuMGI:87870

Back to the top

OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_449

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga8391 ENSANGP00000017971
Anopheles gambiae (Aga) aga3394 ENSANGP00000020372
Ashbya gossypii (Ago) ago1907 ADR165C
Arabidopsis thaliana (Ath) ath26656 At5g47720.1
Arabidopsis thaliana (Ath) ath26657 At5g47720.2
Arabidopsis thaliana (Ath) ath26658 At5g47720.3
Arabidopsis thaliana (Ath) ath26659 At5g47720.4
Arabidopsis thaliana (Ath) ath26717 At5g48230.1
Arabidopsis thaliana (Ath) ath26718 At5g48230.2
Caenorhabditis elegans (Cel) cel14339 T02G5.8
(CE29990;
WBGene00002183)
Candida glabrata (Cgl) cgl4614 CAGL0L12364g
Cryptococcus neoformans (Cne) cne5593 179.m00455
Dictyostelium discoideum (Ddi) ddi11927 DDB0231621
Debaryomyces hansenii (Dha) dha4810 DEHA0F09603g
Drosophila melanogaster (Dme) dme16887 CG10932-PA
(FBgn0029969)
Drosophila melanogaster (Dme) dme7363 CG9149-PA
(FBgn0035203)
Danio rerio (Dre) dre12615 ENSDARP00000018064
(acat2)
Danio rerio (Dre) dre25620 ENSDARP00000031507
Escherichia coli (Eco) eco2155 16130161
Escherichia coli (Eco) eco2748 16130748
Takifugu rubripes (Fru) fru14140 SINFRUP00000142166
Takifugu rubripes (Fru) fru22551 SINFRUP00000152839
Takifugu rubripes (Fru) fru22552 SINFRUP00000167655
Gallus gallus (Gga) gga15156 ENSGALP00000019035
(ACAT2)		 Q5ZHQ4
Gallus gallus (Gga) gga15157 ENSGALP00000019036
Gallus gallus (Gga) gga15158 ENSGALP00000019037
(ACAT2)
Gallus gallus (Gga) gga3228 ENSGALP00000027665
(ACAT1)
Gallus gallus (Gga) gga3229 ENSGALP00000027666
Gallus gallus (Gga) gga3230 ENSGALP00000027667
Homo sapiens (Hsa) hsa27994 ENSP00000239584
Homo sapiens (Hsa) hsa6506 ENSP00000265838
(ACAT1)		 P24752
Kluyveromyces lactis (Kla) kla2598 KLLA0D12056g
Mus musculus (Mmu) mmu31414 ENSMUSP00000007005
(MGI:87871)		 Q8CAY6
Mus musculus (Mmu) mmu27638 ENSMUSP00000034547
(MGI:87870)		 Q8QZT1
Mus musculus (Mmu) mmu31415 ENSMUSP00000045912
(MGI:109182)		 Q80X81
Neurospora crassa (Ncr) ncr2491 NCU02571.2
Neurospora crassa (Ncr) ncr9476 NCU09732.2
Oryza sativa (Osa) osa11432 2773.m00117
Oryza sativa (Osa) osa11451 2773.m00163
Oryza sativa (Osa) osa46111 5697.m00159
Oryza sativa (Osa) osa46143 5697.m00195
Plasmodium falciparum (Pfa) pfa1164 PF14_0484
Rattus norvegicus (Rno) rno28611 ENSRNOP00000010573
(RGD:2016)		 P17764
Rattus norvegicus (Rno) rno448 ENSRNOP00000026003
(RGD:1359366)		 Q5XI22
Rattus norvegicus (Rno) rno449 ENSRNOP00000043959
Rattus norvegicus (Rno) rno447 ENSRNOP00000048489
Saccharomyces cerevisiae (Sce) sce6182 YPL028W
(S000005949)
Schizosaccharomyces pombe (Spo) spo4357 SPBC215.09c Q9UQW6
Yarrowia lipolytica (Yli) yli1090 YALI0B08536g
Yarrowia lipolytica (Yli) yli4322 YALI0E11099g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
AthAt5g47720
PfaPF14_0484
GO:0005739 mitochondrion C
IDA
CelWBGene00002183
MmuMGI:87870
MGI:109182
MGI:87871
ISS
DmeFBgn0029969
GO:0005743 mitochondrial inner membrane C
IDA
MmuMGI:87870
GO:0005759 mitochondrial matrix C
ISO
MmuMGI:87870
GO:0005777 peroxisome C
IDA
AthAt5g48230
GO:0005811 lipid particle C
IDA
DmeFBgn0029969
GO:0005829 cytosol C
IDA
SpoSPBC215.09c
ISO
MmuMGI:87871
ISS
DmeFBgn0035203
SpoSPBC215.09c
TAS
SceS000005949
GO:0005875 microtubule associated complex C
IDA
DmeFBgn0029969
GO:0005886 plasma membrane C
IDA
AthAt5g48230
GO:0003985 acetyl-CoA C-acetyltransferase
activity		 F
IDA
MmuMGI:87870
SceS000005949
ISO
MmuMGI:87870
MGI:87871
ISS
AthAt5g48230
At5g47720
DmeFBgn0029969
FBgn0035203
PfaPF14_0484
SpoSPBC215.09c
GO:0019899 enzyme binding F
ISO
MmuMGI:87870
GO:0042803 protein homodimerization activity F
ISO
MmuMGI:87870
GO:0050662 coenzyme binding F
ISO
MmuMGI:87870
GO:0006066 alcohol metabolic process P
RCA
SceS000005949
GO:0006090 pyruvate metabolic process P
ISS
DmeFBgn0029969
GO:0006631 fatty acid metabolic process P
ISS
PfaPF14_0484
GO:0006633 fatty acid biosynthetic process P
ISS
DmeFBgn0029969
GO:0006696 ergosterol biosynthetic process P
IMP
SceS000005949
ISS
SpoSPBC215.09c
GO:0007052 mitotic spindle organization P
IMP
DmeFBgn0029969
GO:0008152 metabolic process P
IDA
MmuMGI:87870
GO:0009793 embryo development ending in seed
dormancy		 P
NAS
AthAt5g48230
GO:0019915 lipid storage P
IMP
CelWBGene00002183
GO:0043094 cellular metabolic compound salvage P
RCA
SceS000005949
GO:0051260 protein homooligomerization P
ISO
MmuMGI:87870

Back to the top

Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPBC215.09c
(Q9UQW6)		 YPL028W
(S000005949)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005829 cytosol C
IDA
SpoSPBC215.09c
ISS
SpoSPBC215.09c
TAS
SceS000005949
GO:0003985 acetyl-CoA C-acetyltransferase
activity		 F
IDA
SceS000005949
ISS
SpoSPBC215.09c
GO:0006066 alcohol metabolic process P
RCA
SceS000005949
GO:0006696 ergosterol biosynthetic process P
IMP
SceS000005949
ISS
SpoSPBC215.09c
GO:0043094 cellular metabolic compound salvage P
RCA
SceS000005949

Back to the top
YOGY Home YOGY Help

Search for gene by ID or name:

Query species:

Include wild-cards:   

Search for GO info:  

GO info in one table:

s.khadayate@ucl.ac.uk