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Search term: YPL040C

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name ISM1
SGD link S000005961
Alternative ID YPL040C
Description Mitochondrial isoleucyl-tRNA synthetase, null mutant is deficient in respiratory growth
Synonyms YPL040C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

Search for gene by ID or name:

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG0433 ACDHYP-

KOGs classification KOGs description
INFORMATION STORAGE AND PROCESSING Isoleucyl-tRNA synthetase

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At5g49030 GI:15239777
Caenorhabditis elegans (Cel) CE08372 GI:17505707
Caenorhabditis elegans (Cel) CE08373 GI:17505705
Drosophila melanogaster (Dme) 7294186 GI:7294186
Homo sapiens (Hsa) Hs8922356 GI:8922356
Saccharomyces cerevisiae (Sce) YPL040c
(S000005961)		 GI:6325217 P48526
Schizosaccharomyces pombe (Spo) SPCC18B5.08c GI:19075438 Q9USL3
Arabidopsis thaliana (Ath) At5g49030 GI:15239777
Caenorhabditis elegans (Cel) CE08372 GI:17505707
Caenorhabditis elegans (Cel) CE08373 GI:17505705
Drosophila melanogaster (Dme) 7294186 GI:7294186
Homo sapiens (Hsa) Hs8922356 GI:8922356
Saccharomyces cerevisiae (Sce) YPL040c
(S000005961)		 GI:6325217 P48526
Schizosaccharomyces pombe (Spo) SPCC18B5.08c GI:19075438 Q9USL3
Arabidopsis thaliana (Ath) At5g49030 GI:15239777
Caenorhabditis elegans (Cel) CE08372 GI:17505707
Caenorhabditis elegans (Cel) CE08373 GI:17505705
Drosophila melanogaster (Dme) 7294186 GI:7294186
Homo sapiens (Hsa) Hs8922356 GI:8922356
Saccharomyces cerevisiae (Sce) YPL040c
(S000005961)		 GI:6325217 P48526
Schizosaccharomyces pombe (Spo) SPCC18B5.08c GI:19075438 Q9USL3


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005739 mitochondrion C
IDA
SceS000005961
IMP
SceS000005961
ISS
SpoSPCC18B5.08c
GO:0005829 cytosol C
IDA
SpoSPCC18B5.08c
GO:0009507 chloroplast C
IDA
AthAt5g49030
GO:0004812 aminoacyl-tRNA ligase activity F
ISS
AthAt5g49030
GO:0004822 isoleucine-tRNA ligase activity F
ISA
SceS000005961
ISS
SpoSPCC18B5.08c
GO:0005524 ATP binding F
ISS
AthAt5g49030
SpoSPCC18B5.08c
GO:0006418 tRNA aminoacylation for protein
translation		 P
ISS
AthAt5g49030
GO:0006428 isoleucyl-tRNA aminoacylation P
ISA
SceS000005961
ISS
SpoSPCC18B5.08c
GO:0032543 mitochondrial translation P
IMP
SceS000005961
NAS
SpoSPCC18B5.08c
GO:0048481 ovule development P
IMP
AthAt5g49030
GO:0070152 mitochondrial isoleucyl-tRNA aminoacylation P
IC
SceS000005961

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
7118

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) IARS2 GI:46852147
Pan troglodytes (Ptr) IARS2 GI:114572728
Canis familiaris (Cfa) IARS2 GI:74006189
Mus musculus (Mmu) Iars2
(MGI:1919586)		 GI:38490690 Q810V2
Rattus norvegicus (Rno) Iars2 GI:109498339
Gallus gallus (Gga) IARS2 GI:57530344
Drosophila melanogaster (Dme) CG5414
(FBgn0036569)		 GI:24665024
Anopheles gambiae (Aga) AgaP_AGAP003156 GI:158291334
Caenorhabditis elegans (Cel) irs-2
(CE35957;
WBGene00002153)		 GI:71980946
Schizosaccharomyces pombe (Spo) SPCC18B5.08c GI:19075438 Q9USL3
Saccharomyces cerevisiae (Sce) ISM1
(S000005961)		 GI:6325217 P48526
Kluyveromyces lactis (Kla) KLLA0D11858g GI:50307223
Eremothecium gossypii (Ego) AGOS_AGL247C GI:45200850
Magnaporthe grisea (Mgr) MGG_01165 GI:39949929
Neurospora crassa (Ncr) NCU00920.1 GI:32409239
Arabidopsis thaliana (Ath) OVA2 GI:22327660
Oryza sativa (Osa) Os02g0778200 GI:115449027


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005739 mitochondrion C
IDA
MmuMGI:1919586
SceS000005961
IMP
SceS000005961
ISS
SpoSPCC18B5.08c
GO:0005759 mitochondrial matrix C
EXP
HsaIARS2
GO:0005829 cytosol C
IDA
SpoSPCC18B5.08c
GO:0009507 chloroplast C
IDA
AthOVA2
GO:0003674 molecular_function F
ND
MmuMGI:1919586
GO:0004812 aminoacyl-tRNA ligase activity F
ISS
AthOVA2
GO:0004822 isoleucine-tRNA ligase activity F
EXP
HsaIARS2
ISA
SceS000005961
ISS
DmeFBgn0036569
SpoSPCC18B5.08c
GO:0005524 ATP binding F
ISS
AthOVA2
SpoSPCC18B5.08c
GO:0006418 tRNA aminoacylation for protein
translation		 P
ISS
AthOVA2
GO:0006428 isoleucyl-tRNA aminoacylation P
ISA
SceS000005961
ISS
SpoSPCC18B5.08c
GO:0006898 receptor-mediated endocytosis P
IMP
CelWBGene00002153
GO:0008150 biological_process P
ND
MmuMGI:1919586
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00002153
GO:0032543 mitochondrial translation P
IMP
SceS000005961
NAS
SpoSPCC18B5.08c
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00002153
GO:0048481 ovule development P
IMP
AthOVA2
GO:0070152 mitochondrial isoleucyl-tRNA aminoacylation P
IC
SceS000005961

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_1243

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga5444 ENSANGP00000016716
Ashbya gossypii (Ago) ago4065 AGL247C
Arabidopsis thaliana (Ath) ath26814 At5g49030.1
Caenorhabditis elegans (Cel) cel2628 C25A1.7
(CE35957;
WBGene00002153)
Candida glabrata (Cgl) cgl4624 CAGL0L12606g
Cryptococcus neoformans (Cne) cne2790 183.m01731
Dictyostelium discoideum (Ddi) ddi13532 DDB0231256
Debaryomyces hansenii (Dha) dha5349 DEHA0F21648g
Drosophila melanogaster (Dme) dme9720 CG5414-PA
(FBgn0036569)
Danio rerio (Dre) dre7780 ENSDARP00000013994
Escherichia coli (Eco) eco27 16128020
Takifugu rubripes (Fru) fru16939 SINFRUP00000138839
Takifugu rubripes (Fru) fru19023 SINFRUP00000154828
Gallus gallus (Gga) gga14609 ENSGALP00000015561
Gallus gallus (Gga) gga14610 ENSGALP00000015562
Gallus gallus (Gga) gga14606 ENSGALP00000015563
Gallus gallus (Gga) gga14607 ENSGALP00000015565
(IARS2)		 Q5ZKA2
Gallus gallus (Gga) gga14608 ENSGALP00000015566
Homo sapiens (Hsa) hsa3076 ENSP00000303279
(IARS2)		 Q9NSE4
Homo sapiens (Hsa) hsa3077 ENSP00000317770
Kluyveromyces lactis (Kla) kla2589 KLLA0D11858g
Mus musculus (Mmu) mmu1679 ENSMUSP00000027921
(MGI:1919586)		 Q8BIJ6
Neurospora crassa (Ncr) ncr894 NCU00920.2
Oryza sativa (Osa) osa7461 2517.m00091
Oryza sativa (Osa) osa28432 4244.m00123
Plasmodium falciparum (Pfa) pfa5025 PFL1210w
Rattus norvegicus (Rno) rno9739 ENSRNOP00000003222
Saccharomyces cerevisiae (Sce) sce6195 YPL040C
(S000005961)
Schizosaccharomyces pombe (Spo) spo1691 SPCC18B5.08c Q9USL3
Yarrowia lipolytica (Yli) yli2162 YALI0C10780g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005739 mitochondrion C
IDA
MmuMGI:1919586
SceS000005961
IMP
SceS000005961
ISS
SpoSPCC18B5.08c
GO:0005829 cytosol C
IDA
SpoSPCC18B5.08c
GO:0009507 chloroplast C
IDA
AthAt5g49030
GO:0020011 apicoplast C
RCA
PfaPFL1210w
GO:0003674 molecular_function F
ND
MmuMGI:1919586
GO:0004812 aminoacyl-tRNA ligase activity F
ISS
AthAt5g49030
GO:0004822 isoleucine-tRNA ligase activity F
ISA
SceS000005961
ISS
DmeFBgn0036569
SpoSPCC18B5.08c
GO:0005524 ATP binding F
ISS
AthAt5g49030
SpoSPCC18B5.08c
GO:0006418 tRNA aminoacylation for protein
translation		 P
ISS
AthAt5g49030
GO:0006428 isoleucyl-tRNA aminoacylation P
ISA
SceS000005961
ISS
SpoSPCC18B5.08c
GO:0006898 receptor-mediated endocytosis P
IMP
CelWBGene00002153
GO:0008150 biological_process P
ND
MmuMGI:1919586
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00002153
GO:0032543 mitochondrial translation P
IMP
SceS000005961
NAS
SpoSPCC18B5.08c
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00002153
GO:0048481 ovule development P
IMP
AthAt5g49030
GO:0070152 mitochondrial isoleucyl-tRNA aminoacylation P
IC
SceS000005961

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPCC18B5.08c
(Q9USL3)		 YPL040C
(S000005961)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005739 mitochondrion C
IDA
SceS000005961
IMP
SceS000005961
ISS
SpoSPCC18B5.08c
GO:0005829 cytosol C
IDA
SpoSPCC18B5.08c
GO:0004822 isoleucine-tRNA ligase activity F
ISA
SceS000005961
ISS
SpoSPCC18B5.08c
GO:0005524 ATP binding F
ISS
SpoSPCC18B5.08c
GO:0006428 isoleucyl-tRNA aminoacylation P
ISA
SceS000005961
ISS
SpoSPCC18B5.08c
GO:0032543 mitochondrial translation P
IMP
SceS000005961
NAS
SpoSPCC18B5.08c
GO:0070152 mitochondrial isoleucyl-tRNA aminoacylation P
IC
SceS000005961

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Search for gene by ID or name:

Query species:

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Search for GO info:  

GO info in one table:

s.khadayate@ucl.ac.uk