YOGY Home YOGY Help

Search term: YPL063W

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name TIM50
SGD link S000005984
Alternative ID YPL063W
Description Essential component of the Translocase of the Inner Mitochondrial membrane (TIM23 complex); acts as receptor for the TIM23 complex guiding incoming precursors from the TOM complex; may control the gating of the Tim23p-Tim17p channel
Synonyms YPL063W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

Search for gene by ID or name:

Query species:

Include wild-cards:   

Search for GO info:  

GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG2832 ACDHYPE

KOGs classification KOGs description
INFORMATION STORAGE AND PROCESSING TFIIF-interacting CTD phosphatase, including NLI-interacting factor (involved in RNA polymerase II regulation)

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At1g55900 GI:15222797
Caenorhabditis elegans (Cel) CE06481
(WBGene00011897)		 GI:17564536 Q22647
Drosophila melanogaster (Dme) 7290361 GI:7290361
Drosophila melanogaster (Dme) 7291953
(ttm2)		 GI:20130405
Drosophila melanogaster (Dme) 7302145 GI:7302145
Homo sapiens (Hsa) Hs17483190 GI:17483190
Saccharomyces cerevisiae (Sce) YPL063w
(S000005984)		 GI:6325194 Q02776
Schizosaccharomyces pombe (Spo) SPBC17A3.01c GI:19112375 O13636
Encephalitozoon cuniculi (Ecu) ECU10g0580 GI:19074667 Q8SUF8


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005739 mitochondrion C
IDA
AthAt1g55900
SceS000005984
SpoSPBC17A3.01c
GO:0005743 mitochondrial inner membrane C
IDA
AthAt1g55900
GO:0005744 mitochondrial inner membrane presequence
translocase complex		 C
IDA
SceS000005984
ISS
SpoSPBC17A3.01c
GO:0016021 integral to membrane C
ISS
SpoSPBC17A3.01c
GO:0003674 molecular_function F
ND
AthAt1g55900
GO:0015266 protein channel activity F
IMP
SceS000005984
GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane
transporter activity		 F
IC
SpoSPBC17A3.01c
GO:0030943 mitochondrion targeting sequence
binding		 F
IDA
SceS000005984
GO:0000003 reproduction P
IMP
CelWBGene00011897
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00011897
GO:0009793 embryo development ending in seed
dormancy		 P
NAS
AthAt1g55900
GO:0030150 protein import into mitochondrial
matrix		 P
IMP
SceS000005984
ISS
SpoSPBC17A3.01c

Back to the top

HomoloGene results:

HomoloGene cluster Phylogenetic pattern
57031

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) TIMM50 GI:48526509
Pan troglodytes (Ptr) TIMM50 GI:114677195
Canis familiaris (Cfa) TIMM50 GI:73948354
Mus musculus (Mmu) Timm50
(MGI:1913775)		 GI:22094989 Q8BT83
Rattus norvegicus (Rno) Timm50 GI:109458445
Gallus gallus (Gga) TIMM50 GI:118118943
Drosophila melanogaster (Dme) ttm50 GI:18543299
Drosophila melanogaster (Dme) ttm3 GI:24585753
Drosophila melanogaster (Dme) ttm2 GI:20130405
Anopheles gambiae (Aga) AgaP_AGAP001108 GI:158302534
Caenorhabditis elegans (Cel) scpl-4
(CE06481;
WBGene00011897)		 GI:17564536 Q22647
Schizosaccharomyces pombe (Spo) tim50
(SPBC17A3.01c)		 GI:19112375 O13636
Saccharomyces cerevisiae (Sce) TIM50
(S000005984)		 GI:6325194 Q02776
Kluyveromyces lactis (Kla) KLLA0E23188g GI:50309961
Eremothecium gossypii (Ego) AGOS_ADR045W GI:45187918
Magnaporthe grisea (Mgr) MGG_04219 GI:39944416
Neurospora crassa (Ncr) NCU02943.1 GI:32419375


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005739 mitochondrion C
IDA
Dmettm50
MmuMGI:1913775
SceS000005984
SpoSPBC17A3.01c
GO:0005743 mitochondrial inner membrane C
IDA
HsaTIMM50
GO:0005744 mitochondrial inner membrane presequence
translocase complex		 C
IDA
SceS000005984
IPI
HsaTIMM50
ISS
SpoSPBC17A3.01c
GO:0016021 integral to membrane C
ISS
SpoSPBC17A3.01c
GO:0016607 nuclear speck C
IDA
HsaTIMM50
GO:0003674 molecular_function F
ND
Dmettm50
GO:0004721 phosphoprotein phosphatase activity F
IDA
HsaTIMM50
ISA
MmuMGI:1913775
GO:0004722 protein serine/threonine phosphatase
activity		 F
IDA
HsaTIMM50
GO:0004725 protein tyrosine phosphatase activity F
IDA
HsaTIMM50
GO:0005134 interleukin-2 receptor binding F
IDA
HsaTIMM50
ISA
MmuMGI:1913775
GO:0005515 protein binding F
IPI
HsaTIMM50
GO:0015266 protein channel activity F
IMP
SceS000005984
GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane
transporter activity		 F
IC
SpoSPBC17A3.01c
GO:0030943 mitochondrion targeting sequence
binding		 F
IDA
SceS000005984
GO:0043021 ribonucleoprotein binding F
IDA
HsaTIMM50
GO:0000003 reproduction P
IMP
CelWBGene00011897
GO:0001836 release of cytochrome c from mitochondria P
IDA
HsaTIMM50
ISA
MmuMGI:1913775
GO:0006470 protein amino acid dephosphorylation P
IDA
HsaTIMM50
GO:0007005 mitochondrion organization P
IMP
Dmettm50
GO:0007006 mitochondrial membrane organization P
IMP
HsaTIMM50
GO:0007067 mitosis P
NAS
Dmettm50
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00011897
GO:0016311 dephosphorylation P
ISA
MmuMGI:1913775
GO:0030150 protein import into mitochondrial
matrix		 P
IMP
SceS000005984
ISS
SpoSPBC17A3.01c

Back to the top

OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_2278

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga3177 ENSANGP00000004167
Ashbya gossypii (Ago) ago1786 ADR045W
Arabidopsis thaliana (Ath) ath4930 At1g55900.1
Caenorhabditis elegans (Cel) cel15903 T21C9.12
(CE06481;
WBGene00011897)
Candida glabrata (Cgl) cgl2287 CAGL0H05159g
Cryptococcus neoformans (Cne) cne2253 181.m08273
Debaryomyces hansenii (Dha) dha1373 DEHA0B15807g
Drosophila melanogaster (Dme) dme7225 CG12313-PA
(FBgn0035124)
Drosophila melanogaster (Dme) dme16301 CG2713-PA
(FBgn0024978)
Drosophila melanogaster (Dme) dme3317 CG6691-PA
(FBgn0032971)
Danio rerio (Dre) dre6126 ENSDARP00000023107
Danio rerio (Dre) dre6116 ENSDARP00000048422
(timm50)		 Q6NWD4
Encephalitozoon cuniculi (Ecu) ecu583 19074667
Gallus gallus (Gga) gga27134 ENSGALP00000023071
Homo sapiens (Hsa) hsa16366 ENSP00000318115
(TIMM50)		 Q3ZCQ8-2
Kluyveromyces lactis (Kla) kla3993 KLLA0E23188g
Mus musculus (Mmu) mmu23499 ENSMUSP00000080614
(MGI:1913775)		 Q9D880
Neurospora crassa (Ncr) ncr2848 NCU02943.2
Oryza sativa (Osa) osa49050 5833.m00158
Oryza sativa (Osa) osa49101 5835.m00162
Plasmodium falciparum (Pfa) pfa2440 PF07_0110
Saccharomyces cerevisiae (Sce) sce6219 YPL063W
(S000005984)
Schizosaccharomyces pombe (Spo) spo145 SPBC17A3.01c O13636
Yarrowia lipolytica (Yli) yli1610 YALI0B20856g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005739 mitochondrion C
IDA
AthAt1g55900
MmuMGI:1913775
SceS000005984
SpoSPBC17A3.01c
GO:0005743 mitochondrial inner membrane C
IDA
AthAt1g55900
GO:0005744 mitochondrial inner membrane presequence
translocase complex		 C
IDA
SceS000005984
ISS
SpoSPBC17A3.01c
GO:0016021 integral to membrane C
ISS
SpoSPBC17A3.01c
GO:0003674 molecular_function F
ND
AthAt1g55900
GO:0004721 phosphoprotein phosphatase activity F
ISA
MmuMGI:1913775
GO:0005134 interleukin-2 receptor binding F
ISA
MmuMGI:1913775
GO:0015266 protein channel activity F
IMP
SceS000005984
GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane
transporter activity		 F
IC
SpoSPBC17A3.01c
GO:0030943 mitochondrion targeting sequence
binding		 F
IDA
SceS000005984
GO:0000003 reproduction P
IMP
CelWBGene00011897
GO:0001836 release of cytochrome c from mitochondria P
ISA
MmuMGI:1913775
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00011897
GO:0009793 embryo development ending in seed
dormancy		 P
NAS
AthAt1g55900
GO:0016311 dephosphorylation P
ISA
MmuMGI:1913775
GO:0030150 protein import into mitochondrial
matrix		 P
IMP
SceS000005984
ISS
SpoSPBC17A3.01c

Back to the top

Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPBC17A3.01c
(O13636)		 YPL063W
(S000005984)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005739 mitochondrion C
IDA
SceS000005984
SpoSPBC17A3.01c
GO:0005744 mitochondrial inner membrane presequence
translocase complex		 C
IDA
SceS000005984
ISS
SpoSPBC17A3.01c
GO:0016021 integral to membrane C
ISS
SpoSPBC17A3.01c
GO:0015266 protein channel activity F
IMP
SceS000005984
GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane
transporter activity		 F
IC
SpoSPBC17A3.01c
GO:0030943 mitochondrion targeting sequence
binding		 F
IDA
SceS000005984
GO:0030150 protein import into mitochondrial
matrix		 P
IMP
SceS000005984
ISS
SpoSPBC17A3.01c

Back to the top
YOGY Home YOGY Help

Search for gene by ID or name:

Query species:

Include wild-cards:   

Search for GO info:  

GO info in one table:

s.khadayate@ucl.ac.uk