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Search term: YPL094C

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name SEC62
SGD link S000006015
Alternative ID YPL094C
Description Essential subunit of Sec63 complex (Sec63p, Sec62p, Sec66p and Sec72p); with Sec61 complex, Kar2p/BiP and Lhs1p forms a channel competent for SRP-dependent and post-translational SRP-independent protein targeting and import into the ER
Synonyms YPL094C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG2927 ACDHYPE

KOGs classification KOGs description
CELLULAR PROCESSES AND SIGNALING Membrane component of ER protein translocation complex

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At3g20920 GI:18402801
Caenorhabditis elegans (Cel) CE05294 GI:17531983
Drosophila melanogaster (Dme) 7297595 GI:7297595
Homo sapiens (Hsa) Hs4507525
(SEC62)		 GI:4507525 Q99442
Saccharomyces cerevisiae (Sce) YPL094c
(S000006015)		 GI:6325163
Schizosaccharomyces pombe (Spo) SPAC17G6.09 GI:19115168 O13787
Encephalitozoon cuniculi (Ecu) ECU07g0700 GI:19074492 Q8SRK3


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005783 endoplasmic reticulum C
IDA
HsaSEC62
SpoSPAC17G6.09
GO:0005789 endoplasmic reticulum membrane C
ISS
SpoSPAC17G6.09
TAS
SceS000006015
GO:0005791 rough endoplasmic reticulum C
ISS
HsaSEC62
GO:0005886 plasma membrane C
IDA
AthAt3g20920
GO:0016020 membrane C
ISS
AthAt3g20920
GO:0016235 aggresome C
IDA
HsaSEC62
GO:0031207 Sec62/Sec63 complex C
IPI
SceS000006015
ISS
SpoSPAC17G6.09
GO:0045111 intermediate filament cytoskeleton C
IDA
HsaSEC62
GO:0004872 receptor activity F
TAS
HsaSEC62
GO:0005515 protein binding F
IMP
SceS000006015
IPI
SceS000006015
GO:0008565 protein transporter activity F
TAS
SceS000006015
GO:0006613 cotranslational protein targeting to
membrane		 P
TAS
HsaSEC62
GO:0006620 posttranslational protein targeting to
membrane		 P
ISS
SpoSPAC17G6.09
GO:0031204 posttranslational protein targeting to membrane,
translocation		 P
IDA
SceS000006015

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
31975

Species Gene ID NCBI link UniProt link
Schizosaccharomyces pombe (Spo) sec62
(SPAC17G6.09)		 GI:19115168 O13787
Saccharomyces cerevisiae (Sce) SEC62
(S000006015)		 GI:41629689
Kluyveromyces lactis (Kla) KLLA0E24200g GI:50310053
Eremothecium gossypii (Ego) AGOS_ABR196C GI:54299368
Magnaporthe grisea (Mgr) MGG_06172 GI:39975803
Neurospora crassa (Ncr) NCU06333.1 GI:32411415


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005783 endoplasmic reticulum C
IDA
SpoSPAC17G6.09
GO:0005789 endoplasmic reticulum membrane C
ISS
SpoSPAC17G6.09
TAS
SceS000006015
GO:0031207 Sec62/Sec63 complex C
IPI
SceS000006015
ISS
SpoSPAC17G6.09
GO:0005515 protein binding F
IMP
SceS000006015
IPI
SceS000006015
GO:0008565 protein transporter activity F
TAS
SceS000006015
GO:0006620 posttranslational protein targeting to
membrane		 P
ISS
SpoSPAC17G6.09
GO:0031204 posttranslational protein targeting to membrane,
translocation		 P
IDA
SceS000006015

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_2821

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga12040 ENSANGP00000015805
Ashbya gossypii (Ago) ago790 ABR196C
Caenorhabditis elegans (Cel) cel2424 C18E9.2
(CE34703;
WBGene00007683)
Candida glabrata (Cgl) cgl2312 CAGL0H05731g
Cryptococcus neoformans (Cne) cne195 162.m02619
Debaryomyces hansenii (Dha) dha6287 DEHA0G13167g
Drosophila melanogaster (Dme) dme1700 CG4758-PA
(FBgn0011584)
Drosophila melanogaster (Dme) dme1701 CG4758-PB
(FBgn0011584)
Danio rerio (Dre) dre11572 ENSDARP00000027503
(tloc1)		 Q4V8Z6
Encephalitozoon cuniculi (Ecu) ecu1878 19074492
Takifugu rubripes (Fru) fru17215 SINFRUP00000144348
Gallus gallus (Gga) gga23711 ENSGALP00000015260
(TLOC1)		 Q5F3A1
Gallus gallus (Gga) gga23712 ENSGALP00000015261
Homo sapiens (Hsa) hsa23441 ENSP00000337688
(SEC62)		 Q99442
Kluyveromyces lactis (Kla) kla4039 KLLA0E24200g
Mus musculus (Mmu) mmu16458 ENSMUSP00000029256
(MGI:1916526)		 Q8BU14
Neurospora crassa (Ncr) ncr6152 NCU06333.2
Plasmodium falciparum (Pfa) pfa1812 PF14_0361
Rattus norvegicus (Rno) rno15887 ENSRNOP00000012240
(RGD:1308862)		 Q7TP42
Saccharomyces cerevisiae (Sce) sce6250 YPL094C
(S000006015)
Schizosaccharomyces pombe (Spo) spo191 SPAC17G6.09 O13787
Yarrowia lipolytica (Yli) yli1475 YALI0B17512g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
MmuMGI:1916526
GO:0005783 endoplasmic reticulum C
IDA
SpoSPAC17G6.09
GO:0005784 Sec61 translocon complex C
ISS
DmeFBgn0011584
NAS
DmeFBgn0011584
GO:0005789 endoplasmic reticulum membrane C
ISS
SpoSPAC17G6.09
TAS
SceS000006015
GO:0031207 Sec62/Sec63 complex C
IPI
SceS000006015
ISS
SpoSPAC17G6.09
GO:0003674 molecular_function F
ND
MmuMGI:1916526
GO:0005515 protein binding F
IMP
SceS000006015
IPI
SceS000006015
GO:0008565 protein transporter activity F
TAS
SceS000006015
GO:0000003 reproduction P
IMP
CelWBGene00007683
GO:0006614 SRP-dependent cotranslational protein targeting to
membrane		 P
ISS
DmeFBgn0011584
PfaPF14_0361
GO:0006620 posttranslational protein targeting to
membrane		 P
ISS
SpoSPAC17G6.09
GO:0008150 biological_process P
ND
MmuMGI:1916526
GO:0031204 posttranslational protein targeting to membrane,
translocation		 P
IDA
SceS000006015
GO:0040011 locomotion P
IMP
CelWBGene00007683
GO:0040015 negative regulation of multicellular organism
growth		 P
IMP
CelWBGene00007683

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPAC17G6.09
(O13787)		 YPL094C
(S000006015)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005783 endoplasmic reticulum C
IDA
SpoSPAC17G6.09
GO:0005789 endoplasmic reticulum membrane C
ISS
SpoSPAC17G6.09
TAS
SceS000006015
GO:0031207 Sec62/Sec63 complex C
IPI
SceS000006015
ISS
SpoSPAC17G6.09
GO:0005515 protein binding F
IMP
SceS000006015
IPI
SceS000006015
GO:0008565 protein transporter activity F
TAS
SceS000006015
GO:0006620 posttranslational protein targeting to
membrane		 P
ISS
SpoSPAC17G6.09
GO:0031204 posttranslational protein targeting to membrane,
translocation		 P
IDA
SceS000006015

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