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Search term: YPL100W


Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name ATG21
SGD link S000006021
Alternative ID YPL100W
Description Phosphoinositide binding protein required for vesicle formation in the cytoplasm-to-vacuole targeting (Cvt) pathway; binds both phosphatidylinositol (3,5)-bisphosphate and phosphatidylinositol 3-phosphate; WD-40 repeat protein
Synonyms YPL100W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG2110 ACDHYP-

KOGs classification KOGs description
POORLY CHARACTERIZED Uncharacterized conserved protein, contains WD40 repeats

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At4g30510 GI:15234761
Caenorhabditis elegans (Cel) CE10268
(WBGene00018294)
GI:17560874
Drosophila melanogaster (Dme) 7295146 GI:7295146
Drosophila melanogaster (Dme) 7298770 GI:7298770
Homo sapiens (Hsa) Hs7661580 GI:7661580 Q9Y4P8
Homo sapiens (Hsa) Hs7706294 GI:7706294
Homo sapiens (Hsa) Hs8922208 GI:8922208
Saccharomyces cerevisiae (Sce) YFR021w
(S000001917)
GI:16740527 P43601
Saccharomyces cerevisiae (Sce) YPL100w
(S000006021)
GI:6325157 Q02887
Schizosaccharomyces pombe (Spo) SPAC589.07c GI:19114967 Q9HDZ7
Schizosaccharomyces pombe (Spo) SPAC823.16c GI:19114755 Q9P6N1


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000329 fungal-type vacuole membrane C
IDA
SceS000006021
S000001917
ISS
SpoSPAC823.16c
SPAC589.07c
GO:0000407 pre-autophagosomal structure C
IDA
SceS000001917
GO:0005737 cytoplasm C
IDA
SpoSPAC589.07c
GO:0005768 endosome C
IDA
SceS000006021
S000001917
GO:0005794 Golgi apparatus C
IDA
SpoSPAC823.16c
SPAC589.07c
GO:0005829 cytosol C
IDA
SceS000001917
S000006021
ISS
SpoSPAC589.07c
SPAC823.16c
GO:0043234 protein complex C
NAS
SpoSPAC823.16c
SPAC589.07c
GO:0070772 PAS complex C
IDA
SceS000001917
IPI
SceS000001917
GO:0003674 molecular_function F
ND
AthAt4g30510
GO:0035091 phosphoinositide binding F
IDA
SceS000006021
S000001917
ISS
SpoSPAC823.16c
SPAC589.07c
GO:0000422 mitochondrion degradation P
IMP
SceS000006021
GO:0002119 nematode larval development P
IMP
CelWBGene00018294
GO:0006497 protein amino acid lipidation P
IMP
SceS000006021
GO:0006623 protein targeting to vacuole P
ISS
SpoSPAC589.07c
SPAC823.16c
GO:0006624 vacuolar protein processing P
IDA
SceS000001917
IMP
SceS000001917
GO:0006914 autophagy P
IGI
CelWBGene00018294
SpoSPAC589.07c
SPAC823.16c
RCA
SceS000006021
GO:0006995 cellular response to nitrogen starvation P
IGI
SpoSPAC589.07c
SPAC823.16c
GO:0008150 biological_process P
ND
AthAt4g30510
GO:0009792 embryo development ending in birth or egg
hatching
P
IMP
CelWBGene00018294
GO:0012501 programmed cell death P
IGI
CelWBGene00018294
GO:0016050 vesicle organization P
IMP
SceS000006021
GO:0016236 macroautophagy P
IC
SpoSPAC589.07c
SPAC823.16c
IDA
SceS000001917
IMP
SceS000006021
S000001917
GO:0030163 protein catabolic process P
IMP
CelWBGene00018294
GO:0030242 peroxisome degradation P
IMP
SceS000001917
GO:0030437 ascospore formation P
IMP
SpoSPAC823.16c
GO:0032258 CVT pathway P
IDA
SceS000001917
IMP
SceS000006021
S000001917
GO:0034497 protein localization to pre-autophagosomal
structure
P
IMP
SceS000006021
GO:0034727 piecemeal microautophagy of nucleus P
IMP
SceS000001917
S000006021
GO:0040007 growth P
IMP
CelWBGene00018294
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00018294
GO:0040024 dauer larval development P
IGI
CelWBGene00018294
GO:0045184 establishment of protein localization P
RCA
SceS000006021
GO:0045324 late endosome to vacuole transport P
IMP
SceS000001917

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
68962

Species Gene ID NCBI link UniProt link
Saccharomyces cerevisiae (Sce) ATG21
(S000006021)
GI:6325157 Q02887
Kluyveromyces lactis (Kla) KLLA0E24354g GI:50310067
Eremothecium gossypii (Ego) AGOS_ABR189W GI:45185420


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000329 fungal-type vacuole membrane C
IDA
SceS000006021
GO:0005768 endosome C
IDA
SceS000006021
GO:0005829 cytosol C
IDA
SceS000006021
GO:0035091 phosphoinositide binding F
IDA
SceS000006021
GO:0000422 mitochondrion degradation P
IMP
SceS000006021
GO:0006497 protein amino acid lipidation P
IMP
SceS000006021
GO:0006914 autophagy P
RCA
SceS000006021
GO:0016050 vesicle organization P
IMP
SceS000006021
GO:0016236 macroautophagy P
IMP
SceS000006021
GO:0032258 CVT pathway P
IMP
SceS000006021
GO:0034497 protein localization to pre-autophagosomal
structure
P
IMP
SceS000006021
GO:0034727 piecemeal microautophagy of nucleus P
IMP
SceS000006021
GO:0045184 establishment of protein localization P
RCA
SceS000006021

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_17546

Species OrthoMCL
sequence
Model organism
protein page
UniProt link
Ashbya gossypii (Ago) ago782 ABR189W
Candida glabrata (Cgl) cgl2317 CAGL0H05841g
Debaryomyces hansenii (Dha) dha6285 DEHA0G13134g
Takifugu rubripes (Fru) fru20431 SINFRUP00000152847
Takifugu rubripes (Fru) fru20430 SINFRUP00000167659
Kluyveromyces lactis (Kla) kla4046 KLLA0E24354g
Saccharomyces cerevisiae (Sce) sce6257 YPL100W
(S000006021)


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000329 fungal-type vacuole membrane C
IDA
SceS000006021
GO:0005768 endosome C
IDA
SceS000006021
GO:0005829 cytosol C
IDA
SceS000006021
GO:0035091 phosphoinositide binding F
IDA
SceS000006021
GO:0000422 mitochondrion degradation P
IMP
SceS000006021
GO:0006497 protein amino acid lipidation P
IMP
SceS000006021
GO:0006914 autophagy P
RCA
SceS000006021
GO:0016050 vesicle organization P
IMP
SceS000006021
GO:0016236 macroautophagy P
IMP
SceS000006021
GO:0032258 CVT pathway P
IMP
SceS000006021
GO:0034497 protein localization to pre-autophagosomal
structure
P
IMP
SceS000006021
GO:0034727 piecemeal microautophagy of nucleus P
IMP
SceS000006021
GO:0045184 establishment of protein localization P
RCA
SceS000006021

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s.khadayate@ucl.ac.uk