Search term: YPL116W

Gene summary:

KOG results:

KOG name	Phylogenetic pattern (and link to KOGs with this pattern)
KOG1343	ACDHYP-

KOGs classification	KOGs description
INFORMATION STORAGE AND PROCESSING	Histone deacetylase complex, catalytic component HDA1

Species	KOG link	NCBI link	UniProt link
Arabidopsis thaliana (Ath)	At1g08460	GI:18390898
Arabidopsis thaliana (Ath)	At3g18520	GI:15229659
Arabidopsis thaliana (Ath)	At4g33470	GI:7445481
Arabidopsis thaliana (Ath)	At5g61060	GI:15239508
Arabidopsis thaliana (Ath)	At5g61070	GI:15239510
Caenorhabditis elegans (Cel)	CE08062	GI:17550310
Caenorhabditis elegans (Cel)	CE20772 (WBGene00018319)	GI:17540334	Q20296
Caenorhabditis elegans (Cel)	CE20787	GI:17533993
Caenorhabditis elegans (Cel)	CE24411 (WBGene00001838)	GI:17537347	Q9U266
Caenorhabditis elegans (Cel)	CE25887	GI:17540332	Q20296
Drosophila melanogaster (Dme)	7292853	GI:18860041
Drosophila melanogaster (Dme)	7293057	GI:18860039
Homo sapiens (Hsa)	Hs13128864 (HDAC6)	GI:13128864	Q9UBN7
Homo sapiens (Hsa)	Hs13259522	GI:13259522
Homo sapiens (Hsa)	Hs13259524	GI:13259524
Homo sapiens (Hsa)	Hs17158039	GI:17158039	Q9UKV0
Homo sapiens (Hsa)	Hs17158041	GI:17158041	Q9UKV0
Homo sapiens (Hsa)	Hs20070354 (HDAC10)	GI:20070354	Q969S8
Homo sapiens (Hsa)	Hs21237799	GI:21237799
Homo sapiens (Hsa)	Hs4885531	GI:4885531
Homo sapiens (Hsa)	Hs5174481	GI:5174481
Homo sapiens (Hsa)	Hs7662280	GI:7662280	Q9UKV0
Saccharomyces cerevisiae (Sce)	YNL021w (S000004966)	GI:6324307	P53973
Saccharomyces cerevisiae (Sce)	YPL116w (S000006037)	GI:6325141	Q02959
Schizosaccharomyces pombe (Spo)	SPBC800.03	GI:19111896	P56523

GO terms for KOG results:

GO ID	GO term	GO aspect	Evidence codes and associations
GO:0000118	histone deacetylase complex	C	IDA Hsa HDAC10 HDAC6 NAS Spo SPBC800.03
GO:0000790	nuclear chromatin	C	IDA Spo SPBC800.03
GO:0005575	cellular_component	C	ND Ath At1g08460 At5g61070
GO:0005634	nucleus	C	IDA Ath At5g61060 Hsa HDAC10 Sce S000006037 Spo SPBC800.03 ISS Hsa HDAC6
GO:0005654	nucleoplasm	C	IDA Hsa HDAC10
GO:0005721	centromeric heterochromatin	C	IDA Spo SPBC800.03
GO:0005737	cytoplasm	C	IDA Ath At5g61060 Hsa HDAC10 Sce S000006037 ISS Hsa HDAC6
GO:0005829	cytosol	C	ISS Hsa HDAC6
GO:0005874	microtubule	C	IDA Hsa HDAC6
GO:0005875	microtubule associated complex	C	IDA Hsa HDAC6
GO:0005901	caveola	C	IDA Hsa HDAC6
GO:0005935	cellular bud neck	C	IDA Sce S000006037
GO:0009507	chloroplast	C	IDA Ath At4g33470
GO:0016234	inclusion body	C	IDA Hsa HDAC6
GO:0016235	aggresome	C	IDA Hsa HDAC6
GO:0016581	NuRD complex	C	IDA Spo SPBC800.03
GO:0030286	dynein complex	C	IDA Hsa HDAC6
GO:0030874	nucleolar chromatin	C	IDA Spo SPBC800.03
GO:0031252	cell leading edge	C	IDA Hsa HDAC6
GO:0031933	telomeric heterochromatin	C	IDA Spo SPBC800.03
GO:0031934	mating-type region heterochromatin	C	IDA Spo SPBC800.03
GO:0033553	rDNA heterochromatin	C	IDA Spo SPBC800.03
GO:0048471	perinuclear region of cytoplasm	C	IDA Hsa HDAC6
GO:0070823	HDA1 complex	C	IDA Sce S000004966 IPI Sce S000004966
GO:0003682	chromatin binding	F	IDA Sce S000004966
GO:0004402	histone acetyltransferase activity	F	ISS Ath At5g61070
GO:0004407	histone deacetylase activity	F	IDA Hsa HDAC6 HDAC10 Sce S000004966 S000006037 Spo SPBC800.03 IMP Spo SPBC800.03 ISS Ath At5g61060 At4g33470 At3g18520 At1g08460 At5g61070 Cel WBGene00001838
GO:0005515	protein binding	F	IPI Hsa HDAC6 HDAC10
GO:0008013	beta-catenin binding	F	IPI Hsa HDAC6
GO:0008017	microtubule binding	F	IDA Hsa HDAC6 ISS Hsa HDAC6
GO:0016564	transcription repressor activity	F	IDA Hsa HDAC10
GO:0016566	specific transcriptional repressor activity	F	IDA Hsa HDAC10 ISS Hsa HDAC6
GO:0019899	enzyme binding	F	IPI Hsa HDAC10 ISS Hsa HDAC6
GO:0031078	histone deacetylase activity (H3-K14 specific)	F	IMP Spo SPBC800.03
GO:0031593	polyubiquitin binding	F	IDA Hsa HDAC6
GO:0033558	protein deacetylase activity	F	IDA Hsa HDAC10 ISS Cel WBGene00018319
GO:0042826	histone deacetylase binding	F	IDA Hsa HDAC10 IPI Hsa HDAC6
GO:0042903	tubulin deacetylase activity	F	IDA Hsa HDAC6 ISS Hsa HDAC6
GO:0043014	alpha-tubulin binding	F	IDA Hsa HDAC6
GO:0048156	tau protein binding	F	IDA Hsa HDAC6
GO:0051879	Hsp90 protein binding	F	IDA Hsa HDAC6
GO:0070840	dynein complex binding	F	IDA Hsa HDAC6
GO:0000003	reproduction	P	RCA Sce S000006037
GO:0000083	regulation of transcription involved in G1/S phase of mitotic cell cycle	P	IGI Sce S000006037 IPI Sce S000006037
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	P	IDA Hsa HDAC10 IMP Spo SPBC800.03
GO:0000183	chromatin silencing at rDNA	P	IMP Spo SPBC800.03
GO:0001308	loss of chromatin silencing involved in replicative cell aging	P	IGI Sce S000004966 IMP Sce S000004966
GO:0006338	chromatin remodeling	P	ISS Ath At5g61070
GO:0006348	chromatin silencing at telomere	P	IMP Spo SPBC800.03
GO:0006355	regulation of transcription, DNA-dependent	P	IDA Hsa HDAC10
GO:0006357	regulation of transcription from RNA polymerase II promoter	P	IEP Spo SPBC800.03
GO:0006476	protein amino acid deacetylation	P	IDA Hsa HDAC10 IMP Hsa HDAC6
GO:0006515	misfolded or incompletely synthesized protein catabolic process	P	IMP Hsa HDAC6
GO:0006886	intracellular protein transport	P	IMP Hsa HDAC6
GO:0009294	DNA mediated transformation	P	IMP Ath At3g18520
GO:0009636	response to toxin	P	IMP Hsa HDAC6
GO:0009967	positive regulation of signal transduction	P	IMP Hsa HDAC6
GO:0010033	response to organic substance	P	IMP Hsa HDAC6
GO:0010469	regulation of receptor activity	P	IMP Hsa HDAC6
GO:0010552	positive regulation of gene-specific transcription from RNA polymerase II promoter	P	IMP Sce S000006037 S000004966
GO:0010553	negative regulation of gene-specific transcription from RNA polymerase II promoter	P	IMP Sce S000004966
GO:0010621