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Search term: YPL138C


Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name SPP1
SGD link S000006059
Alternative ID YPL138C
Description Subunit of COMPASS (Set1C), a complex which methylates histone H3 on lysine 4 and is required in telomeric transcriptional silencing; interacts with Orc2p; PHD finger domain protein similar to human CGBP, an unmethylated CpG binding protein
Synonyms YPL138C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG1632 ACDHYP-

KOGs classification KOGs description
POORLY CHARACTERIZED Uncharacterized PHD Zn-finger protein

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At1g14510 GI:15223786
Arabidopsis thaliana (Ath) At2g02470 GI:15226967
Arabidopsis thaliana (Ath) At3g11200 GI:15229696
Arabidopsis thaliana (Ath) At3g42790 GI:15229157
Arabidopsis thaliana (Ath) At4g22140_2 GI:15234729
Arabidopsis thaliana (Ath) At4g39100_2 GI:7484948
Arabidopsis thaliana (Ath) At5g05610 GI:15239180
Arabidopsis thaliana (Ath) At5g20510 GI:15241376
Arabidopsis thaliana (Ath) At5g26210 GI:15239624
Caenorhabditis elegans (Cel) CE15909 GI:17533489
Caenorhabditis elegans (Cel) CE15910 GI:17533491
Caenorhabditis elegans (Cel) CE24921 GI:17533487
Caenorhabditis elegans (Cel) CE28562 GI:17540568
Drosophila melanogaster (Dme) 7291044 GI:7291044
Drosophila melanogaster (Dme) 7291045 GI:7291045 Q9W352
Drosophila melanogaster (Dme) 7295832 GI:7295832
Homo sapiens (Hsa) Hs17459397 GI:17459397
Homo sapiens (Hsa) Hs18375617 GI:18375617 Q9NUM8
Homo sapiens (Hsa) Hs18375621 GI:18375621
Homo sapiens (Hsa) Hs18587767 GI:18587767
Homo sapiens (Hsa) Hs18588283 GI:18588283
Homo sapiens (Hsa) Hs20558994 GI:20558994
Homo sapiens (Hsa) Hs7656975 GI:7656975
Saccharomyces cerevisiae (Sce) YPL138c
(S000006059)
GI:6325119 Q03012
Schizosaccharomyces pombe (Spo) SPCC594.05c GI:19075291 O74508


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000790 nuclear chromatin C
IC
SpoSPCC594.05c
GO:0005575 cellular_component C
ND
AthAt4g22140
GO:0005634 nucleus C
IDA
AthAt5g26210
At3g42790
At3g11200
At1g14510
At5g20510
At2g02470
At5g05610
At4g39100
SpoSPCC594.05c
GO:0005829 cytosol C
IDA
SpoSPCC594.05c
GO:0048188 Set1C/COMPASS complex C
IDA
SpoSPCC594.05c
IPI
SceS000006059
GO:0003677 DNA binding F
ISS
AthAt2g02470
At3g11200
At5g20510
At3g42790
At1g14510
At5g26210
At5g05610
At4g22140
GO:0003682 chromatin binding F
IDA
SceS000006059
GO:0003700 transcription factor activity F
ISS
AthAt4g39100
GO:0019787 small conjugating protein ligase
activity
F
ISS
SpoSPCC594.05c
GO:0035064 methylated histone residue binding F
IDA
AthAt5g26210
At5g05610
At1g14510
SceS000006059
ISS
AthAt5g20510
At3g42790
At2g02470
At3g11200
GO:0042156 zinc-mediated transcriptional activator
activity
F
ISS
AthAt4g39100
GO:0042800 histone methyltransferase activity (H3-K4
specific)
F
IDA
SceS000006059
IMP
SceS000006059
GO:0006338 chromatin remodeling P
IC
SpoSPCC594.05c
GO:0006348 chromatin silencing at telomere P
IMP
SceS000006059
GO:0006355 regulation of transcription, DNA-dependent P
IMP
SceS000006059
ISS
AthAt3g11200
At4g22140
At5g26210
At2g02470
At5g05610
At1g14510
At3g42790
At5g20510
GO:0006730 one-carbon metabolic process P
RCA
SceS000006059
GO:0009791 post-embryonic development P
IMP
AthAt4g39100
GO:0009845 seed germination P
IMP
AthAt4g22140
GO:0009890 negative regulation of biosynthetic
process
P
RCA
SceS000006059
GO:0009911 positive regulation of flower development P
IGI
AthAt4g22140
GO:0016481 negative regulation of transcription P
RCA
SceS000006059
GO:0051568 histone H3-K4 methylation P
IDA
SceS000006059
IMP
SceS000006059
GO:0051569 regulation of histone H3-K4 methylation P
IMP
SpoSPCC594.05c

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
40436

Species Gene ID NCBI link UniProt link
Saccharomyces cerevisiae (Sce) SPP1
(S000006059)
GI:6325119 Q03012
Kluyveromyces lactis (Kla) KLLA0D07260g GI:50306819
Eremothecium gossypii (Ego) AGOS_ACR115W GI:45185801


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0048188 Set1C/COMPASS complex C
IPI
SceS000006059
GO:0003682 chromatin binding F
IDA
SceS000006059
GO:0035064 methylated histone residue binding F
IDA
SceS000006059
GO:0042800 histone methyltransferase activity (H3-K4
specific)
F
IDA
SceS000006059
IMP
SceS000006059
GO:0006348 chromatin silencing at telomere P
IMP
SceS000006059
GO:0006355 regulation of transcription, DNA-dependent P
IMP
SceS000006059
GO:0006730 one-carbon metabolic process P
RCA
SceS000006059
GO:0009890 negative regulation of biosynthetic
process
P
RCA
SceS000006059
GO:0016481 negative regulation of transcription P
RCA
SceS000006059
GO:0051568 histone H3-K4 methylation P
IDA
SceS000006059
IMP
SceS000006059

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_3985

Species OrthoMCL
sequence
Model organism
protein page
UniProt link
Anopheles gambiae (Aga) aga40 ENSANGP00000003620
Ashbya gossypii (Ago) ago1162 ACR115W
Caenorhabditis elegans (Cel) cel9797 F52B11.1a
(CE33791;
WBGene00009924)
Caenorhabditis elegans (Cel) cel9798 F52B11.1b
(CE33792)
Candida glabrata (Cgl) cgl4769 CAGL0M02585g
Cryptococcus neoformans (Cne) cne4269 177.m03026
Cryptococcus neoformans (Cne) cne4270 177.m03392
Debaryomyces hansenii (Dha) dha6486 DEHA0G17556g
Drosophila melanogaster (Dme) dme17137 CG17446-PA
(FBgn0030121)
Danio rerio (Dre) dre2759 ENSDARP00000032784
(cxxc1)
Q7SZE4
Takifugu rubripes (Fru) fru8173 SINFRUP00000138106
Takifugu rubripes (Fru) fru23135 SINFRUP00000164828
Takifugu rubripes (Fru) fru23136 SINFRUP00000165838
Takifugu rubripes (Fru) fru23134 SINFRUP00000170822
Takifugu rubripes (Fru) fru8174 SINFRUP00000174372
Homo sapiens (Hsa) hsa14974 ENSP00000285106
(CXXC1)
Q9P0U4
Kluyveromyces lactis (Kla) kla2384 KLLA0D07260g
Mus musculus (Mmu) mmu12913 ENSMUSP00000025444
(MGI:1921572)
Q9CWW7
Rattus norvegicus (Rno) rno14381 ENSRNOP00000020472
(RGD:1310755)
A1A5S2
Saccharomyces cerevisiae (Sce) sce6297 YPL138C
(S000006059)
Schizosaccharomyces pombe (Spo) spo4620 SPCC594.05c O74508


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000790 nuclear chromatin C
IC
SpoSPCC594.05c
GO:0005634 nucleus C
IDA
SpoSPCC594.05c
GO:0005829 cytosol C
IDA
SpoSPCC594.05c
GO:0016363 nuclear matrix C
IDA
MmuMGI:1921572
GO:0048188 Set1C/COMPASS complex C
IDA
SpoSPCC594.05c
IPI
SceS000006059
GO:0003682 chromatin binding F
IDA
SceS000006059
GO:0019787 small conjugating protein ligase
activity
F
ISS
SpoSPCC594.05c
GO:0035064 methylated histone residue binding F
IDA
SceS000006059
GO:0042800 histone methyltransferase activity (H3-K4
specific)
F
IDA
SceS000006059
IMP
SceS000006059
GO:0006338 chromatin remodeling P
IC
SpoSPCC594.05c
GO:0006348 chromatin silencing at telomere P
IMP
SceS000006059
GO:0006355 regulation of transcription, DNA-dependent P
IMP
SceS000006059
GO:0006730 one-carbon metabolic process P
RCA
SceS000006059
GO:0009890 negative regulation of biosynthetic
process
P
RCA
SceS000006059
GO:0016481 negative regulation of transcription P
RCA
SceS000006059
GO:0051568 histone H3-K4 methylation P
IDA
SceS000006059
IMP
SceS000006059
GO:0051569 regulation of histone H3-K4 methylation P
IMP
SpoSPCC594.05c

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Curated yeast ortholog results:

S. pombe
systematic ID
S. cerevisiae
systematic ID
SPCC594.05c
(O74508)
YPL138C
(S000006059)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000790 nuclear chromatin C
IC
SpoSPCC594.05c
GO:0005634 nucleus C
IDA
SpoSPCC594.05c
GO:0005829 cytosol C
IDA
SpoSPCC594.05c
GO:0048188 Set1C/COMPASS complex C
IDA
SpoSPCC594.05c
IPI
SceS000006059
GO:0003682 chromatin binding F
IDA
SceS000006059
GO:0019787 small conjugating protein ligase
activity
F
ISS
SpoSPCC594.05c
GO:0035064 methylated histone residue binding F
IDA
SceS000006059
GO:0042800 histone methyltransferase activity (H3-K4
specific)
F
IDA
SceS000006059
IMP
SceS000006059
GO:0006338 chromatin remodeling P
IC
SpoSPCC594.05c
GO:0006348 chromatin silencing at telomere P
IMP
SceS000006059
GO:0006355 regulation of transcription, DNA-dependent P
IMP
SceS000006059
GO:0006730 one-carbon metabolic process P
RCA
SceS000006059
GO:0009890 negative regulation of biosynthetic
process
P
RCA
SceS000006059
GO:0016481 negative regulation of transcription P
RCA
SceS000006059
GO:0051568 histone H3-K4 methylation P
IDA
SceS000006059
IMP
SceS000006059
GO:0051569 regulation of histone H3-K4 methylation P
IMP
SpoSPCC594.05c

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GO info in one table:

s.khadayate@ucl.ac.uk