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Search term: YPL146C

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name NOP53
SGD link S000006067
Alternative ID YPL146C
Description Nucleolar protein; involved in biogenesis of the 60S subunit of the ribosome; interacts with rRNA processing factors Cbf5p and Nop2p; null mutant is viable but growth is severely impaired
Synonyms YPL146C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG2823 ACDHYP-

KOGs classification KOGs description
POORLY CHARACTERIZED Cellular protein (glioma tumor suppressor candidate region gene 2)

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At2g40430 GI:15226683
Caenorhabditis elegans (Cel) CE21690 GI:17565538
Drosophila melanogaster (Dme) 7290969
(FBgn0030061)		 GI:18858059
Homo sapiens (Hsa) Hs22055277 GI:22055277
Homo sapiens (Hsa) Hs7657130
(GLTSCR2)		 GI:7657130
Saccharomyces cerevisiae (Sce) YPL146c
(S000006067)		 GI:6325111 Q12080
Schizosaccharomyces pombe (Spo) SPAC22F8.09 GI:19115644 Q9UUI4


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
AthAt2g40430
DmeFBgn0030061
GO:0005622 intracellular C
NAS
HsaGLTSCR2
GO:0005634 nucleus C
IDA
SceS000006067
GO:0005730 nucleolus C
IDA
SceS000006067
ISS
SpoSPAC22F8.09
GO:0003674 molecular_function F
ND
AthAt2g40430
DmeFBgn0030061
HsaGLTSCR2
SpoSPAC22F8.09
GO:0019843 rRNA binding F
IDA
SceS000006067
GO:0000055 ribosomal large subunit export from
nucleus		 P
IMP
SceS000006067
ISS
SpoSPAC22F8.09
GO:0000463 maturation of LSU-rRNA from tricistronic rRNA
transcript (SSU-rRNA, 5.8S rRNA,
LSU-rRNA)		 P
IMP
SceS000006067
GO:0006364 rRNA processing P
NAS
SpoSPAC22F8.09
GO:0008150 biological_process P
ND
AthAt2g40430
DmeFBgn0030061
HsaGLTSCR2
GO:0042254 ribosome biogenesis P
ISS
SpoSPAC22F8.09

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
44130

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) GLTSCR2 GI:7657130
Pan troglodytes (Ptr) GLTSCR2 GI:114678122
Canis familiaris (Cfa) GLTSCR2 GI:73948075
Mus musculus (Mmu) Gltscr2
(MGI:2154441)		 GI:21539653 Q3USL3
Rattus norvegicus (Rno) Gltscr2
(RGD:1303085)		 GI:46485444
Drosophila melanogaster (Dme) CG1785
(FBgn0030061)		 GI:18858059
Anopheles gambiae (Aga) AgaP_AGAP000270 GI:119115048
Caenorhabditis elegans (Cel) Y39B6A.33 GI:25151557
Schizosaccharomyces pombe (Spo) nop53 GI:19115644
Saccharomyces cerevisiae (Sce) NOP53
(S000006067)		 GI:6325111 Q12080
Kluyveromyces lactis (Kla) KLLA0F11506g GI:50311161
Eremothecium gossypii (Ego) AGOS_ACR126W GI:45185812
Magnaporthe grisea (Mgr) MGG_04142 GI:39944262
Neurospora crassa (Ncr) NCU05233.1 GI:32408217
Arabidopsis thaliana (Ath) AT2G40430 GI:18405381
Oryza sativa (Osa) Os05g0144200 GI:115462047


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
AthAt2g40430
DmeFBgn0030061
MmuMGI:2154441
GO:0005622 intracellular C
NAS
HsaGLTSCR2
GO:0005634 nucleus C
IDA
SceS000006067
GO:0005730 nucleolus C
IDA
SceS000006067
GO:0003674 molecular_function F
ND
AthAt2g40430
DmeFBgn0030061
HsaGLTSCR2
MmuMGI:2154441
GO:0019843 rRNA binding F
IDA
SceS000006067
GO:0000003 reproduction P
IMP
CelY39B6A.33
GO:0000055 ribosomal large subunit export from
nucleus		 P
IMP
SceS000006067
GO:0000463 maturation of LSU-rRNA from tricistronic rRNA
transcript (SSU-rRNA, 5.8S rRNA,
LSU-rRNA)		 P
IMP
SceS000006067
GO:0002119 nematode larval development P
IMP
CelY39B6A.33
GO:0006898 receptor-mediated endocytosis P
IMP
CelY39B6A.33
GO:0008150 biological_process P
ND
AthAt2g40430
DmeFBgn0030061
HsaGLTSCR2
MmuMGI:2154441
GO:0040007 growth P
IMP
CelY39B6A.33
GO:0040010 positive regulation of growth rate P
IMP
CelY39B6A.33

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_4217

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga14866 ENSANGP00000012427
Ashbya gossypii (Ago) ago1173 ACR126W
Arabidopsis thaliana (Ath) ath11181 At2g40430.1
Caenorhabditis elegans (Cel) cel18514 Y39B6A.33
Candida glabrata (Cgl) cgl4761 CAGL0M02409g
Cryptococcus neoformans (Cne) cne2231 181.m08251
Dictyostelium discoideum (Ddi) ddi909 DDB0189380
Debaryomyces hansenii (Dha) dha2187 DEHA0C17094g
Drosophila melanogaster (Dme) dme17040 CG1785-PA
(FBgn0030061)
Danio rerio (Dre) dre11558 ENSDARP00000004473
(zgc:123178)		 Q32LR6
Takifugu rubripes (Fru) fru12915 SINFRUP00000143449
Homo sapiens (Hsa) hsa16718 ENSP00000246802
(GLTSCR2)		 Q9NZM5
Homo sapiens (Hsa) hsa16719 ENSP00000324079
(GLTSCR2)		 A6NNJ5
Kluyveromyces lactis (Kla) kla4604 KLLA0F11506g
Mus musculus (Mmu) mmu23179 ENSMUSP00000043981
(MGI:2154441)		 Q3USL3
Neurospora crassa (Ncr) ncr5080 NCU05233.2
Oryza sativa (Osa) osa17801 3320.m00087
Rattus norvegicus (Rno) rno1100 ENSRNOP00000017556
(RGD:1303085)		 Q6QLN3
Saccharomyces cerevisiae (Sce) sce6305 YPL146C
(S000006067)
Schizosaccharomyces pombe (Spo) spo805 SPAC22F8.09 Q9UUI4
Yarrowia lipolytica (Yli) yli179 YALI0A05181g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
AthAt2g40430
DmeFBgn0030061
MmuMGI:2154441
GO:0005634 nucleus C
IDA
SceS000006067
GO:0005730 nucleolus C
IDA
SceS000006067
ISS
SpoSPAC22F8.09
GO:0003674 molecular_function F
ND
AthAt2g40430
DmeFBgn0030061
MmuMGI:2154441
SpoSPAC22F8.09
GO:0019843 rRNA binding F
IDA
SceS000006067
GO:0000003 reproduction P
IMP
CelY39B6A.33
GO:0000055 ribosomal large subunit export from
nucleus		 P
IMP
SceS000006067
ISS
SpoSPAC22F8.09
GO:0000463 maturation of LSU-rRNA from tricistronic rRNA
transcript (SSU-rRNA, 5.8S rRNA,
LSU-rRNA)		 P
IMP
SceS000006067
GO:0002119 nematode larval development P
IMP
CelY39B6A.33
GO:0006364 rRNA processing P
NAS
SpoSPAC22F8.09
GO:0006898 receptor-mediated endocytosis P
IMP
CelY39B6A.33
GO:0008150 biological_process P
ND
AthAt2g40430
DmeFBgn0030061
MmuMGI:2154441
GO:0040007 growth P
IMP
CelY39B6A.33
GO:0040010 positive regulation of growth rate P
IMP
CelY39B6A.33
GO:0042254 ribosome biogenesis P
ISS
SpoSPAC22F8.09

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPAC22F8.09
(Q9UUI4)		 YPL146C
(S000006067)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SceS000006067
GO:0005730 nucleolus C
IDA
SceS000006067
ISS
SpoSPAC22F8.09
GO:0003674 molecular_function F
ND
SpoSPAC22F8.09
GO:0019843 rRNA binding F
IDA
SceS000006067
GO:0000055 ribosomal large subunit export from
nucleus		 P
IMP
SceS000006067
ISS
SpoSPAC22F8.09
GO:0000463 maturation of LSU-rRNA from tricistronic rRNA
transcript (SSU-rRNA, 5.8S rRNA,
LSU-rRNA)		 P
IMP
SceS000006067
GO:0006364 rRNA processing P
NAS
SpoSPAC22F8.09
GO:0042254 ribosome biogenesis P
ISS
SpoSPAC22F8.09

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