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Search term: YPL157W

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name TGS1
SGD link S000006078
Alternative ID YPL157W
Description Trimethyl guanosine synthase, conserved nucleolar methyl transferase that converts the m(7)G cap structure of snRNAs, snoRNAs, and telomerase TLC1 RNA to m(2,2,7)G; also required for ribosome synthesis and nucleolar morphology
Synonyms YPL157W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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Search for GO info:  

GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG2730 AC-HYP-

KOGs classification KOGs description
POORLY CHARACTERIZED Methylase

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At1g30550 GI:15221438
Caenorhabditis elegans (Cel) CE23958
(WBGene00011631)		 GI:17508967 Q94013
Homo sapiens (Hsa) Hs19923661 GI:19923661
Saccharomyces cerevisiae (Sce) YPL157w
(S000006078)		 GI:6325100 Q12052
Schizosaccharomyces pombe (Spo) SPAC2G11.15c GI:19114007 Q09814
Schizosaccharomyces pombe (Spo) SPAC521.01 GI:19114008


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SpoSPAC2G11.15c
GO:0005730 nucleolus C
IDA
SceS000006078
ISS
SpoSPAC2G11.15c
GO:0005737 cytoplasm C
IDA
SpoSPAC2G11.15c
GO:0005816 spindle pole body C
IDA
SpoSPAC2G11.15c
GO:0005819 spindle C
IDA
SpoSPAC2G11.15c
GO:0005829 cytosol C
IDA
SpoSPAC2G11.15c
GO:0003674 molecular_function F
ND
AthAt1g30550
GO:0008173 RNA methyltransferase activity F
IDA
SceS000006078
IMP
SceS000006078
ISS
SceS000006078
GO:0008990 rRNA (guanine-N2-)-methyltransferase
activity		 F
IMP
SpoSPAC2G11.15c
GO:0001302 replicative cell aging P
IMP
SceS000006078
GO:0002119 nematode larval development P
IMP
CelWBGene00011631
GO:0006364 rRNA processing P
RCA
SceS000006078
GO:0006387 snRNA capping P
IMP
SceS000006078
SpoSPAC2G11.15c
GO:0007000 nucleolus organization P
IMP
SceS000006078
GO:0007004 telomere maintenance via telomerase P
IMP
SceS000006078
GO:0008150 biological_process P
ND
AthAt1g30550
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00011631
GO:0016246 RNA interference P
IMP
CelWBGene00011631
GO:0031167 rRNA methylation P
IMP
SpoSPAC2G11.15c
GO:0040007 growth P
IMP
CelWBGene00011631
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00011631
GO:0040011 locomotion P
IMP
CelWBGene00011631
GO:0042254 ribosome biogenesis P
IMP
SceS000006078

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
117928

Species Gene ID NCBI link UniProt link
Mus musculus (Mmu) Gm5117 GI:82916707
Mus musculus (Mmu) Tgs1
(MGI:2151797)		 GI:50233914 Q8CCI3
Drosophila melanogaster (Dme) CG31241
(FBgn0051241)		 GI:24647901
Saccharomyces cerevisiae (Sce) TGS1
(S000006078)		 GI:6325100 Q12052
Kluyveromyces lactis (Kla) KLLA0D05995g GI:50306711
Eremothecium gossypii (Ego) AGOS_ACR147C GI:45185833


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
ISA
MmuMGI:2151797
GO:0005730 nucleolus C
IDA
SceS000006078
GO:0005737 cytoplasm C
ISA
MmuMGI:2151797
GO:0005515 protein binding F
IPI
MmuMGI:2151797
GO:0008173 RNA methyltransferase activity F
IDA
SceS000006078
IMP
SceS000006078
ISS
SceS000006078
GO:0001302 replicative cell aging P
IMP
SceS000006078
GO:0006364 rRNA processing P
RCA
SceS000006078
GO:0006387 snRNA capping P
IMP
SceS000006078
GO:0007000 nucleolus organization P
IMP
SceS000006078
GO:0007004 telomere maintenance via telomerase P
IMP
SceS000006078
GO:0042254 ribosome biogenesis P
IMP
SceS000006078

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_2242

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga7332 ENSANGP00000022416
Ashbya gossypii (Ago) ago1194 ACR147C
Arabidopsis thaliana (Ath) ath3194 At1g30550.1
Arabidopsis thaliana (Ath) ath3950 At1g45231.2
Caenorhabditis elegans (Cel) cel15031 T08G11.4
(CE23958;
WBGene00011631)
Candida glabrata (Cgl) cgl4749 CAGL0M02145g
Cryptococcus neoformans (Cne) cne3017 167.m03319
Dictyostelium discoideum (Ddi) ddi8068 DDB0187987
Debaryomyces hansenii (Dha) dha1819 DEHA0C08833g
Drosophila melanogaster (Dme) dme13199 CG31241-PA
(FBgn0051241)
Danio rerio (Dre) dre5371 ENSDARP00000046451
Takifugu rubripes (Fru) fru7123 SINFRUP00000144869
Gallus gallus (Gga) gga11139 ENSGALP00000024711
(TGS1)		 Q5ZJ77
Gallus gallus (Gga) gga11138 ENSGALP00000024712
Homo sapiens (Hsa) hsa30315 ENSP00000260129
(TGS1)		 Q96RS0
Kluyveromyces lactis (Kla) kla2328 KLLA0D05995g
Mus musculus (Mmu) mmu25821 ENSMUSP00000033984
Mus musculus (Mmu) mmu17770 ENSMUSP00000054112
(MGI:2151797)		 Q923W1
Neurospora crassa (Ncr) ncr8985 NCU09218.2
Oryza sativa (Osa) osa19876 3380.m00137
Oryza sativa (Osa) osa64927 6722.m00194
Rattus norvegicus (Rno) rno22711 ENSRNOP00000010783
(RGD:1309953)		 P85107
Saccharomyces cerevisiae (Sce) sce6317 YPL157W
(S000006078)
Schizosaccharomyces pombe (Spo) spo485 SPAC2G11.15c Q09814
Yarrowia lipolytica (Yli) yli936 YALI0B04774g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
AthAt1g45231
GO:0005634 nucleus C
IDA
SpoSPAC2G11.15c
ISA
MmuMGI:2151797
GO:0005730 nucleolus C
IDA
SceS000006078
ISS
SpoSPAC2G11.15c
GO:0005737 cytoplasm C
IDA
SpoSPAC2G11.15c
ISA
MmuMGI:2151797
GO:0005816 spindle pole body C
IDA
SpoSPAC2G11.15c
GO:0005819 spindle C
IDA
SpoSPAC2G11.15c
GO:0005829 cytosol C
IDA
SpoSPAC2G11.15c
GO:0003674 molecular_function F
ND
AthAt1g30550
GO:0005515 protein binding F
IPI
MmuMGI:2151797
GO:0008173 RNA methyltransferase activity F
IDA
SceS000006078
IMP
SceS000006078
ISS
SceS000006078
GO:0008990 rRNA (guanine-N2-)-methyltransferase
activity		 F
IMP
SpoSPAC2G11.15c
GO:0001302 replicative cell aging P
IMP
SceS000006078
GO:0002119 nematode larval development P
IMP
CelWBGene00011631
GO:0006364 rRNA processing P
RCA
SceS000006078
GO:0006387 snRNA capping P
IMP
SceS000006078
SpoSPAC2G11.15c
GO:0007000 nucleolus organization P
IMP
SceS000006078
GO:0007004 telomere maintenance via telomerase P
IMP
SceS000006078
GO:0008150 biological_process P
ND
AthAt1g30550
At1g45231
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00011631
GO:0016246 RNA interference P
IMP
CelWBGene00011631
GO:0031167 rRNA methylation P
IMP
SpoSPAC2G11.15c
GO:0040007 growth P
IMP
CelWBGene00011631
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00011631
GO:0040011 locomotion P
IMP
CelWBGene00011631
GO:0042254 ribosome biogenesis P
IMP
SceS000006078

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPAC2G11.15c
(Q09814)		 YPL157W
(S000006078)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SpoSPAC2G11.15c
GO:0005730 nucleolus C
IDA
SceS000006078
ISS
SpoSPAC2G11.15c
GO:0005737 cytoplasm C
IDA
SpoSPAC2G11.15c
GO:0005816 spindle pole body C
IDA
SpoSPAC2G11.15c
GO:0005819 spindle C
IDA
SpoSPAC2G11.15c
GO:0005829 cytosol C
IDA
SpoSPAC2G11.15c
GO:0008173 RNA methyltransferase activity F
IDA
SceS000006078
IMP
SceS000006078
ISS
SceS000006078
GO:0008990 rRNA (guanine-N2-)-methyltransferase
activity		 F
IMP
SpoSPAC2G11.15c
GO:0001302 replicative cell aging P
IMP
SceS000006078
GO:0006364 rRNA processing P
RCA
SceS000006078
GO:0006387 snRNA capping P
IMP
SceS000006078
SpoSPAC2G11.15c
GO:0007000 nucleolus organization P
IMP
SceS000006078
GO:0007004 telomere maintenance via telomerase P
IMP
SceS000006078
GO:0031167 rRNA methylation P
IMP
SpoSPAC2G11.15c
GO:0042254 ribosome biogenesis P
IMP
SceS000006078

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Search for GO info:  

GO info in one table:

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