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Search term: YPL164C

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name MLH3
SGD link S000006085
Alternative ID YPL164C
Description Protein involved in DNA mismatch repair and crossing-over during meiotic recombination; forms a complex with Mlh1p; mammalian homolog is implicated mammalian microsatellite instability
Synonyms YPL164C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG1977 A--HY--

KOGs classification KOGs description
INFORMATION STORAGE AND PROCESSING DNA mismatch repair protein - MLH3 family

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At4g35520 GI:15237032
Homo sapiens (Hsa) Hs7657337 GI:7657337
Saccharomyces cerevisiae (Sce) YPL164c
(S000006085)		 GI:6325093 Q12083


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IPI
SceS000006085
GO:0005694 chromosome C
IDA
AthAt4g35520
GO:0032390 MutLbeta complex C
IPI
SceS000006085
GO:0003674 molecular_function F
ND
SceS000006085
GO:0005524 ATP binding F
ISS
AthAt4g35520
GO:0006298 mismatch repair P
IMP
SceS000006085
ISS
AthAt4g35520
GO:0007131 reciprocal meiotic recombination P
IMP
AthAt4g35520
SceS000006085

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
117927

Species Gene ID NCBI link UniProt link
Saccharomyces cerevisiae (Sce) MLH3
(S000006085)		 GI:6325093 Q12083
Kluyveromyces lactis (Kla) KLLA0C10032g GI:50305373
Magnaporthe grisea (Mgr) MGG_03284 GI:145608202
Neurospora crassa (Ncr) NCU05385.1 GI:32409519


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IPI
SceS000006085
GO:0032390 MutLbeta complex C
IPI
SceS000006085
GO:0003674 molecular_function F
ND
SceS000006085
GO:0006298 mismatch repair P
IMP
SceS000006085
GO:0007131 reciprocal meiotic recombination P
IMP
SceS000006085

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_4749

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Ashbya gossypii (Ago) ago94 AAL093C
Arabidopsis thaliana (Ath) ath21709 At4g35520.1
Candida glabrata (Cgl) cgl4741 CAGL0M01980g
Cryptococcus neoformans (Cne) cne666 163.m03870
Dictyostelium discoideum (Ddi) ddi6236 DDB0218537
Debaryomyces hansenii (Dha) dha3730 DEHA0E11066g
Danio rerio (Dre) dre15646 ENSDARP00000029251
Takifugu rubripes (Fru) fru28806 SINFRUP00000152696
Gallus gallus (Gga) gga19566 ENSGALP00000016748
Homo sapiens (Hsa) hsa9835 ENSP00000238662
(MLH3)		 Q9UHC1-2
Homo sapiens (Hsa) hsa9836 ENSP00000348020
(MLH3)		 Q9UHC1-1
Kluyveromyces lactis (Kla) kla1645 KLLA0C10032g
Mus musculus (Mmu) mmu6004 ENSMUSP00000058534
Mus musculus (Mmu) mmu6003 ENSMUSP00000066124
Neurospora crassa (Ncr) ncr5230 NCU05385.2
Oryza sativa (Osa) osa48614 5671.m00106
Oryza sativa (Osa) osa51373 5976.m00181
Rattus norvegicus (Rno) rno25444 ENSRNOP00000008775
(RGD:1309227)
Rattus norvegicus (Rno) rno25445 ENSRNOP00000038334
(RGD:1309227)
Saccharomyces cerevisiae (Sce) sce6324 YPL164C
(S000006085)


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IPI
SceS000006085
GO:0005694 chromosome C
IDA
AthAt4g35520
GO:0032390 MutLbeta complex C
IPI
SceS000006085
GO:0003674 molecular_function F
ND
SceS000006085
GO:0005524 ATP binding F
ISS
AthAt4g35520
GO:0006298 mismatch repair P
IMP
SceS000006085
ISS
AthAt4g35520
GO:0007131 reciprocal meiotic recombination P
IMP
AthAt4g35520
SceS000006085

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