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Search term: YPL170W


Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name DAP1
SGD link S000006091
Alternative ID YPL170W
Description Heme-binding protein involved in regulation of cytochrome P450 protein Erg11p; damage response protein, related to mammalian membrane progesterone receptors; mutations lead to defects in telomeres, mitochondria, and sterol synthesis
Synonyms YPL170W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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Query species:

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GO info in one table:


KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG1110 ACDHYP-

KOGs classification KOGs description
POORLY CHARACTERIZED Putative steroid membrane receptor Hpr6.6/25-Dx

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At2g24940 GI:15224648
Arabidopsis thaliana (Ath) At3g48890 GI:15229044
Arabidopsis thaliana (Ath) At5g52240 GI:15242943
Caenorhabditis elegans (Cel) CE21027
(WBGene00006890)
GI:17570189
Drosophila melanogaster (Dme) 7293150
(FBgn0030703)
GI:18859969
Drosophila melanogaster (Dme) 7296039 GI:7296039
Drosophila melanogaster (Dme) 7298060 GI:7298060
Homo sapiens (Hsa) Hs5453916
(PGRMC2)
GI:5453916 O15173
Homo sapiens (Hsa) Hs7019545
(NENF)
GI:7019545 Q9UMX5
Homo sapiens (Hsa) Hs20558707 GI:20558707
Homo sapiens (Hsa) Hs5729875
(PGRMC1)
GI:5729875 O00264
Saccharomyces cerevisiae (Sce) YPL170w
(S000006091)
GI:6325087 Q12091
Schizosaccharomyces pombe (Spo) SPAC26H5.15 GI:19115373
Arabidopsis thaliana (Ath) At2g24940 GI:15224648
Arabidopsis thaliana (Ath) At3g48890 GI:15229044
Arabidopsis thaliana (Ath) At5g52240 GI:15242943
Caenorhabditis elegans (Cel) CE21027
(WBGene00006890)
GI:17570189
Drosophila melanogaster (Dme) 7293150
(FBgn0030703)
GI:18859969
Drosophila melanogaster (Dme) 7296039 GI:7296039
Drosophila melanogaster (Dme) 7298060 GI:7298060
Homo sapiens (Hsa) Hs5453916
(PGRMC2)
GI:5453916 O15173
Homo sapiens (Hsa) Hs7019545
(NENF)
GI:7019545 Q9UMX5
Homo sapiens (Hsa) Hs20558707 GI:20558707
Homo sapiens (Hsa) Hs5729875
(PGRMC1)
GI:5729875 O00264
Saccharomyces cerevisiae (Sce) YPL170w
(S000006091)
GI:6325087 Q12091
Schizosaccharomyces pombe (Spo) SPAC26H5.15 GI:19115373


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
AthAt2g24940
GO:0005634 nucleus C
IDA
AthAt3g48890
HsaPGRMC1
GO:0005730 nucleolus C
IDA
HsaPGRMC1
GO:0005768 endosome C
IDA
SceS000006091
GO:0005783 endoplasmic reticulum C
IDA
AthAt5g52240
HsaPGRMC1
GO:0005886 plasma membrane C
IDA
AthAt5g52240
DmeFBgn0030703
GO:0009535 chloroplast thylakoid membrane C
IDA
AthAt3g48890
GO:0009986 cell surface C
IDA
HsaPGRMC1
GO:0016020 membrane C
ISS
SceS000006091
GO:0030424 axon C
IDA
CelWBGene00006890
GO:0003707 steroid hormone receptor activity F
TAS
HsaPGRMC2
GO:0005496 steroid binding F
IDA
AthAt5g52240
GO:0005515 protein binding F
IPI
HsaPGRMC1
GO:0020037 heme binding F
IDA
SceS000006091
GO:0035100 ecdysone binding F
IDA
DmeFBgn0030703
GO:0007411 axon guidance P
IMP
CelWBGene00006890
GO:0030308 negative regulation of cell growth P
IMP
AthAt5g52240
GO:0032443 regulation of ergosterol biosynthetic
process
P
IGI
SceS000006091
IMP
SceS000006091

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
48457

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) PGRMC1 GI:5729875 O00264
Pan troglodytes (Ptr) PGRMC1 GI:114689965
Canis familiaris (Cfa) PGRMC1 GI:57112339
Mus musculus (Mmu) Pgrmc1
(MGI:1858305)
GI:31980806 O55022
Rattus norvegicus (Rno) Pgrmc1
(RGD:70890)
GI:11120720
Gallus gallus (Gga) PGRMC1 GI:118089686
Drosophila melanogaster (Dme) CG9066
(FBgn0030703)
GI:18859969
Anopheles gambiae (Aga) AgaP_AGAP000767 GI:158289619
Caenorhabditis elegans (Cel) vem-1
(CE21027;
WBGene00006890)
GI:71993293
Schizosaccharomyces pombe (Spo) dap1
(SPAC25B8.01)
GI:19115373 O13995
Saccharomyces cerevisiae (Sce) DAP1
(S000006091)
GI:6325087 Q12091
Kluyveromyces lactis (Kla) KLLA0C09757g GI:50305347
Eremothecium gossypii (Ego) AGOS_AAL106W GI:45184718
Magnaporthe grisea (Mgr) MGG_00274 GI:145611592
Neurospora crassa (Ncr) NCU07286.1 GI:32414185
Arabidopsis thaliana (Ath) MSBP1 GI:15242943


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
HsaPGRMC1
GO:0005730 nucleolus C
IDA
HsaPGRMC1
GO:0005768 endosome C
IDA
SceS000006091
GO:0005783 endoplasmic reticulum C
IDA
AthMSBP1
HsaPGRMC1
SpoSPAC25B8.01
GO:0005789 endoplasmic reticulum membrane C
IC
SpoSPAC25B8.01
GO:0005886 plasma membrane C
IDA
AthMSBP1
DmeFBgn0030703
GO:0009986 cell surface C
IDA
HsaPGRMC1
GO:0016020 membrane C
ISS
SceS000006091
SpoSPAC25B8.01
GO:0030424 axon C
IDA
CelWBGene00006890
GO:0005496 steroid binding F
IDA
AthMSBP1
ISS
SpoSPAC25B8.01
GO:0005515 protein binding F
IPI
HsaPGRMC1
SpoSPAC25B8.01
GO:0008047 enzyme activator activity F
IMP
SpoSPAC25B8.01
GO:0020037 heme binding F
IDA
SceS000006091
SpoSPAC25B8.01
GO:0035100 ecdysone binding F
IDA
DmeFBgn0030703
GO:0006696 ergosterol biosynthetic process P
IEP
SpoSPAC25B8.01
IMP
SpoSPAC25B8.01
GO:0007411 axon guidance P
IMP
CelWBGene00006890
GO:0030308 negative regulation of cell growth P
IMP
AthMSBP1
GO:0032443 regulation of ergosterol biosynthetic
process
P
IGI
SceS000006091
IMP
SceS000006091

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_1372

Species OrthoMCL
sequence
Model organism
protein page
UniProt link
Anopheles gambiae (Aga) aga15434 ENSANGP00000017486
Ashbya gossypii (Ago) ago81 AAL106W
Arabidopsis thaliana (Ath) ath9412 At2g24940.1
Arabidopsis thaliana (Ath) ath16197 At3g48890.1
Arabidopsis thaliana (Ath) ath27176 At5g52240.1
Caenorhabditis elegans (Cel) cel12152 K07E3.8a
(CE21027;
WBGene00006890)
Caenorhabditis elegans (Cel) cel12153 K07E3.8b
(CE34578)
Candida glabrata (Cgl) cgl1382 CAGL0F03553g
Cryptococcus neoformans (Cne) cne1635 164.m01516
Cryptococcus neoformans (Cne) cne5395 179.m00247
Cryptococcus neoformans (Cne) cne5396 179.m00248
Dictyostelium discoideum (Ddi) ddi6776 DDB0204917
Debaryomyces hansenii (Dha) dha4769 DEHA0F08723g
Debaryomyces hansenii (Dha) dha5106 DEHA0F16170g
Drosophila melanogaster (Dme) dme18057 CG9066-PA
(FBgn0030703)
Danio rerio (Dre) dre13899 ENSDARP00000012321
Takifugu rubripes (Fru) fru3459 SINFRUP00000143799
Gallus gallus (Gga) gga14670 ENSGALP00000015952
(NENF)
Gallus gallus (Gga) gga17431 ENSGALP00000016583
(PGRMC2)
Q5ZLX0
Homo sapiens (Hsa) hsa33293 ENSP00000217971
(PGRMC1)
O00264
Homo sapiens (Hsa) hsa3031 ENSP00000261463
Kluyveromyces lactis (Kla) kla1632 KLLA0C09757g
Mus musculus (Mmu) mmu1731 ENSMUSP00000046311
(MGI:1913458)
Q9CQ45
Mus musculus (Mmu) mmu28826 ENSMUSP00000073061
(MGI:1858305)
O55022
Neurospora crassa (Ncr) ncr4089 NCU04213.2
Neurospora crassa (Ncr) ncr7092 NCU07286.2
Oryza sativa (Osa) osa5912 2467.m00127
Oryza sativa (Osa) osa564 43.m00073
Oryza sativa (Osa) osa566 43.m00075
Oryza sativa (Osa) osa32770 4473.m00129
Oryza sativa (Osa) osa33567 4538.m00155
Rattus norvegicus (Rno) rno9785 ENSRNOP00000005190
(RGD:1303289)
Q6IUR5
Rattus norvegicus (Rno) rno30723 ENSRNOP00000017101
(RGD:70890)
P70580
Saccharomyces cerevisiae (Sce) sce6330 YPL170W
(S000006091)
Schizosaccharomyces pombe (Spo) spo4426 SPAC25B8.01 O13995
Yarrowia lipolytica (Yli) yli700 YALI0A20394g
Yarrowia lipolytica (Yli) yli4858 YALI0E24079g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
AthAt2g24940
GO:0005615 extracellular space C
IDA
MmuMGI:1913458
GO:0005634 nucleus C
IDA
AthAt3g48890
GO:0005768 endosome C
IDA
SceS000006091
GO:0005783 endoplasmic reticulum C
IDA
AthAt5g52240
SpoSPAC25B8.01
GO:0005789 endoplasmic reticulum membrane C
IC
SpoSPAC25B8.01
GO:0005886 plasma membrane C
IDA
AthAt5g52240
DmeFBgn0030703
GO:0009535 chloroplast thylakoid membrane C
IDA
AthAt3g48890
GO:0016020 membrane C
ISS
SceS000006091
SpoSPAC25B8.01
GO:0030424 axon C
IDA
CelWBGene00006890
GO:0005496 steroid binding F
IDA
AthAt5g52240
ISS
SpoSPAC25B8.01
GO:0005515 protein binding F
IPI
SpoSPAC25B8.01
GO:0008047 enzyme activator activity F
IMP
SpoSPAC25B8.01
GO:0008083 growth factor activity F
IDA
MmuMGI:1913458
GO:0020037 heme binding F
IDA
SceS000006091
SpoSPAC25B8.01
GO:0035100 ecdysone binding F
IDA
DmeFBgn0030703
GO:0006696 ergosterol biosynthetic process P
IEP
SpoSPAC25B8.01
IMP
SpoSPAC25B8.01
GO:0007411 axon guidance P
IMP
CelWBGene00006890
GO:0030308 negative regulation of cell growth P
IMP
AthAt5g52240
GO:0032443 regulation of ergosterol biosynthetic
process
P
IGI
SceS000006091
IMP
SceS000006091
GO:0043410 positive regulation of MAPKKK cascade P
IDA
MmuMGI:1913458

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Curated yeast ortholog results:

S. pombe
systematic ID
S. cerevisiae
systematic ID
SPAC25B8.01
(O13995)
YPL170W
(S000006091)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005768 endosome C
IDA
SceS000006091
GO:0005783 endoplasmic reticulum C
IDA
SpoSPAC25B8.01
GO:0005789 endoplasmic reticulum membrane C
IC
SpoSPAC25B8.01
GO:0016020 membrane C
ISS
SceS000006091
SpoSPAC25B8.01
GO:0005496 steroid binding F
ISS
SpoSPAC25B8.01
GO:0005515 protein binding F
IPI
SpoSPAC25B8.01
GO:0008047 enzyme activator activity F
IMP
SpoSPAC25B8.01
GO:0020037 heme binding F
IDA
SceS000006091
SpoSPAC25B8.01
GO:0006696 ergosterol biosynthetic process P
IEP
SpoSPAC25B8.01
IMP
SpoSPAC25B8.01
GO:0032443 regulation of ergosterol biosynthetic
process
P
IGI
SceS000006091
IMP
SceS000006091

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Search for gene by ID or name:

Query species:

Include wild-cards:   

Search for GO info:  

GO info in one table:

s.khadayate@ucl.ac.uk