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Search term: YPL175W


Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name SPT14
SGD link S000006096
Alternative ID YPL175W
Description UDP-GlcNAc-binding and catalytic subunit of the enzyme that mediates the first step in glycosylphosphatidylinositol (GPI) biosynthesis, mutations cause defects in transcription and in biogenesis of cell wall proteins
Synonyms YPL175W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG1111 ACDHYPE

KOGs classification KOGs description
CELLULAR PROCESSES AND SIGNALINGCELLULAR PROCESSES AND SIGNALINGMETABOLISM N-acetylglucosaminyltransferase complex, subunit PIG-A/SPT14, required for phosphatidylinositol biosynthesis/Sulfolipid synthase

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At3g45100 GI:11277021
Arabidopsis thaliana (Ath) At5g01220 GI:11357835
Caenorhabditis elegans (Cel) CE03109
(WBGene00008431)
GI:17532709 Q18993
Drosophila melanogaster (Dme) 7302724 GI:7302724
Homo sapiens (Hsa) Hs11863126_2 GI:11863126
Homo sapiens (Hsa) Hs11863130_2
(PIGA)
GI:11863130 P37287
Saccharomyces cerevisiae (Sce) YPL175w
(S000006096)
GI:9755344 P32363
Schizosaccharomyces pombe (Spo) SPBC3D6.07 GI:19112311 P87172
Encephalitozoon cuniculi (Ecu) ECU09g1210 GI:19173240
Arabidopsis thaliana (Ath) At3g45100 GI:11277021
Arabidopsis thaliana (Ath) At5g01220 GI:11357835
Caenorhabditis elegans (Cel) CE03109
(WBGene00008431)
GI:17532709 Q18993
Drosophila melanogaster (Dme) 7302724 GI:7302724
Homo sapiens (Hsa) Hs11863126_2 GI:11863126
Homo sapiens (Hsa) Hs11863130_2
(PIGA)
GI:11863130 P37287
Saccharomyces cerevisiae (Sce) YPL175w
(S000006096)
GI:9755344 P32363
Schizosaccharomyces pombe (Spo) SPBC3D6.07 GI:19112311 P87172
Encephalitozoon cuniculi (Ecu) ECU09g1210 GI:19173240


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase
(GPI-GnT) complex
C
IDA
HsaPIGA
ISS
SpoSPBC3D6.07
TAS
SceS000006096
GO:0005575 cellular_component C
ND
AthAt3g45100
GO:0005783 endoplasmic reticulum C
IMP
SceS000006096
ISS
SpoSPBC3D6.07
GO:0005789 endoplasmic reticulum membrane C
IDA
HsaPIGA
GO:0009507 chloroplast C
IDA
AthAt5g01220
GO:0009941 chloroplast envelope C
IDA
AthAt5g01220
GO:0005515 protein binding F
IPI
HsaPIGA
GO:0008194 UDP-glycosyltransferase activity F
IDA
AthAt5g01220
IPI
SceS000006096
ISS
SceS000006096
SpoSPBC3D6.07
GO:0016757 transferase activity, transferring glycosyl
groups
F
ISS
AthAt5g01220
At3g45100
GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase
activity
F
NAS
SpoSPBC3D6.07
TAS
HsaPIGA
GO:0046510 UDP-sulfoquinovose:DAG sulfoquinovosyltransferase
activity
F
IDA
AthAt5g01220
GO:0006506 GPI anchor biosynthetic process P
ISS
AthAt3g45100
SpoSPBC3D6.07
TAS
HsaPIGA
SceS000006096
GO:0009247 glycolipid biosynthetic process P
IDA
AthAt5g01220
GO:0009893 positive regulation of metabolic
process
P
TAS
HsaPIGA
GO:0016036 cellular response to phosphate
starvation
P
IMP
AthAt5g01220
GO:0016254 preassembly of GPI anchor in ER
membrane
P
EXP
HsaPIGA
GO:0045132 meiotic chromosome segregation P
IMP
CelWBGene00008431
GO:0046506 sulfolipid biosynthetic process P
TAS
AthAt5g01220

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
1982

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) PIGA GI:11863130 P37287
Pan troglodytes (Ptr) PIGA GI:114687855
Canis familiaris (Cfa) PIGA GI:57111901
Mus musculus (Mmu) Piga
(MGI:99461)
GI:126273666 A2AIH5
Rattus norvegicus (Rno) Piga GI:34880068
Gallus gallus (Gga) PIGA GI:71895221
Drosophila melanogaster (Dme) CG6401
(FBgn0034270)
GI:24654571
Anopheles gambiae (Aga) AgaP_AGAP011274 GI:158287315
Caenorhabditis elegans (Cel) D2085.6
(CE03109;
WBGene00008431)
GI:17532709 Q18993
Schizosaccharomyces pombe (Spo) gpi3
(SPBC3D6.07)
GI:19112311 P87172
Saccharomyces cerevisiae (Sce) SPT14
(S000006096)
GI:9755344 P32363
Kluyveromyces lactis (Kla) KLLA0C09713g GI:50305343
Eremothecium gossypii (Ego) AGOS_AAL108C GI:45184716
Magnaporthe grisea (Mgr) MGG_03933 GI:39943844
Neurospora crassa (Ncr) NCU09757.1 GI:32419927
Arabidopsis thaliana (Ath) SETH2 GI:18407913
Plasmodium falciparum (Pfa) PF10_0316 GI:124802802


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase
(GPI-GnT) complex
C
IDA
HsaPIGA
ISS
SpoSPBC3D6.07
TAS
SceS000006096
GO:0005575 cellular_component C
ND
AthSETH2
GO:0005783 endoplasmic reticulum C
IMP
SceS000006096
ISS
SpoSPBC3D6.07
GO:0005789 endoplasmic reticulum membrane C
IDA
HsaPIGA
GO:0030176 integral to endoplasmic reticulum
membrane
C
ISS
DmeFBgn0034270
GO:0003824 catalytic activity F
ISS
PfaPF10_0316
GO:0005515 protein binding F
IPI
HsaPIGA
GO:0008194 UDP-glycosyltransferase activity F
IPI
SceS000006096
ISS
SceS000006096
SpoSPBC3D6.07
GO:0016757 transferase activity, transferring glycosyl
groups
F
ISS
AthSETH2
GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase
activity
F
ISS
DmeFBgn0034270
NAS
SpoSPBC3D6.07
TAS
HsaPIGA
GO:0006506 GPI anchor biosynthetic process P
ISS
AthSETH2
DmeFBgn0034270
PfaPF10_0316
SpoSPBC3D6.07
TAS
HsaPIGA
SceS000006096
GO:0009893 positive regulation of metabolic
process
P
TAS
HsaPIGA
GO:0016254 preassembly of GPI anchor in ER
membrane
P
EXP
HsaPIGA
GO:0045132 meiotic chromosome segregation P
IMP
CelWBGene00008431

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_517

Species OrthoMCL
sequence
Model organism
protein page
UniProt link
Anopheles gambiae (Aga) aga8326 ENSANGP00000014890
Ashbya gossypii (Ago) ago79 AAL108C
Arabidopsis thaliana (Ath) ath15788 At3g45100.1
Arabidopsis thaliana (Ath) ath15789 At3g45100.2
Caenorhabditis elegans (Cel) cel5125 D2085.6
(CE03109;
WBGene00008431)
Candida glabrata (Cgl) cgl1384 CAGL0F03597g
Cryptococcus neoformans (Cne) cne821 163.m06126
Dictyostelium discoideum (Ddi) ddi13327 DDB0231698
Debaryomyces hansenii (Dha) dha5104 DEHA0F16126g
Drosophila melanogaster (Dme) dme5719 CG6401-PA
(FBgn0034270)
Danio rerio (Dre) dre23656 ENSDARP00000015286
Escherichia coli (Eco) eco1983 16129984
Escherichia coli (Eco) eco3511 16131502
Encephalitozoon cuniculi (Ecu) ecu1391 19173240
Takifugu rubripes (Fru) fru13040 SINFRUP00000156519
Gallus gallus (Gga) gga2412 ENSGALP00000026670
(PIGA)
Q5F4C8
Homo sapiens (Hsa) hsa32474 ENSP00000297902
Kluyveromyces lactis (Kla) kla1630 KLLA0C09713g
Mus musculus (Mmu) mmu29860 ENSMUSP00000033754
(MGI:99461)
Q64323
Neurospora crassa (Ncr) ncr9501 NCU09757.2
Oryza sativa (Osa) osa3966 2077.m00126
Oryza sativa (Osa) osa39037 5085.m00078
Plasmodium falciparum (Pfa) pfa534 PF10_0316
Rattus norvegicus (Rno) rno31290 ENSRNOP00000004733
(RGD:1589723)
Saccharomyces cerevisiae (Sce) sce6335 YPL175W
(S000006096)
Schizosaccharomyces pombe (Spo) spo2072 SPBC3D6.07 P87172
Yarrowia lipolytica (Yli) yli704 YALI0A20482g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase
(GPI-GnT) complex
C
ISS
SpoSPBC3D6.07
TAS
SceS000006096
GO:0005575 cellular_component C
ND
AthAt3g45100
GO:0005783 endoplasmic reticulum C
IMP
SceS000006096
ISS
SpoSPBC3D6.07
GO:0030176 integral to endoplasmic reticulum
membrane
C
ISS
DmeFBgn0034270
GO:0003824 catalytic activity F
ISS
PfaPF10_0316
GO:0008194 UDP-glycosyltransferase activity F
IPI
SceS000006096
ISS
SceS000006096
SpoSPBC3D6.07
GO:0016757 transferase activity, transferring glycosyl
groups
F
ISS
AthAt3g45100
GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase
activity
F
ISS
DmeFBgn0034270
NAS
SpoSPBC3D6.07
GO:0006506 GPI anchor biosynthetic process P
ISS
AthAt3g45100
DmeFBgn0034270
PfaPF10_0316
SpoSPBC3D6.07
TAS
SceS000006096
GO:0045132 meiotic chromosome segregation P
IMP
CelWBGene00008431

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Curated yeast ortholog results:

S. pombe
systematic ID
S. cerevisiae
systematic ID
SPBC3D6.07
(P87172)
YPL175W
(S000006096)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase
(GPI-GnT) complex
C
ISS
SpoSPBC3D6.07
TAS
SceS000006096
GO:0005783 endoplasmic reticulum C
IMP
SceS000006096
ISS
SpoSPBC3D6.07
GO:0008194 UDP-glycosyltransferase activity F
IPI
SceS000006096
ISS
SceS000006096
SpoSPBC3D6.07
GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase
activity
F
NAS
SpoSPBC3D6.07
GO:0006506 GPI anchor biosynthetic process P
ISS
SpoSPBC3D6.07
TAS
SceS000006096

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Search for gene by ID or name:

Query species:

Include wild-cards:   

Search for GO info:  

GO info in one table:

s.khadayate@ucl.ac.uk