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Search term: YPL189W

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name GUP2
SGD link S000006110
Alternative ID YPL189W
Description Probable membrane protein with a possible role in proton symport of glycerol; member of the MBOAT family of putative membrane-bound O-acyltransferases; Gup1p homolog
Synonyms YPL189W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG3860 ACDHYP-

KOGs classification KOGs description
CELLULAR PROCESSES AND SIGNALING Acyltransferase required for palmitoylation of Hedgehog (Hh) family of secreted signaling proteins

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At1g57600 GI:15223623
Caenorhabditis elegans (Cel) CE14958 GI:17543772
Drosophila melanogaster (Dme) 7292318
(FBgn0024194)		 GI:17647931
Homo sapiens (Hsa) Hs21359937 GI:18490309 Q9HCP6
Homo sapiens (Hsa) Hs8922621 GI:8922621
Homo sapiens (Hsa) HsM14149736 GI:14149736
Saccharomyces cerevisiae (Sce) YGL084c
(S000003052)		 GI:6321354 P53154
Saccharomyces cerevisiae (Sce) YPL189w
(S000006110)		 GI:6325067 Q08929
Schizosaccharomyces pombe (Spo) SPAC24H6.01c GI:19113863 Q09758
Schizosaccharomyces pombe (Spo) SPAPB21F2.01 GI:19113864


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005783 endoplasmic reticulum C
IDA
SceS000003052
GO:0005789 endoplasmic reticulum membrane C
ISS
SpoSPAC24H6.01c
GO:0005829 cytosol C
IDA
SpoSPAC24H6.01c
GO:0005886 plasma membrane C
IDA
SceS000003052
ISS
SpoSPAC24H6.01c
NAS
DmeFBgn0024194
GO:0016020 membrane C
IDA
SceS000003052
ISS
AthAt1g57600
SceS000006110
S000003052
GO:0016021 integral to membrane C
NAS
DmeFBgn0024194
GO:0008374 O-acyltransferase activity F
IMP
SceS000003052
ISS
SceS000006110
SpoSPAC24H6.01c
GO:0008415 acyltransferase activity F
IMP
DmeFBgn0024194
ISS
AthAt1g57600
NAS
DmeFBgn0024194
GO:0016409 palmitoyltransferase activity F
IMP
DmeFBgn0024194
GO:0006506 GPI anchor biosynthetic process P
IMP
SceS000003052
ISS
SpoSPAC24H6.01c
GO:0007047 cellular cell wall organization P
RCA
SceS000003052
GO:0007224 smoothened signaling pathway P
IMP
DmeFBgn0024194
NAS
DmeFBgn0024194
GO:0007225 patched ligand maturation P
IMP
DmeFBgn0024194
NAS
DmeFBgn0024194
GO:0007367 segment polarity determination P
IMP
DmeFBgn0024194
GO:0008150 biological_process P
ND
AthAt1g57600
GO:0015793 glycerol transport P
IGI
SceS000006110
S000003052
IMP
SceS000003052
ISS
SpoSPAC24H6.01c
GO:0018009 N-terminal peptidyl-L-cysteine
N-palmitoylation		 P
IDA
DmeFBgn0024194
IMP
DmeFBgn0024194
GO:0018318 protein amino acid palmitoylation P
NAS
DmeFBgn0024194
GO:0018345 protein palmitoylation P
IDA
DmeFBgn0024194
GO:0019563 glycerol catabolic process P
IGI
SceS000003052
IMP
SceS000003052
GO:0044262 cellular carbohydrate metabolic
process		 P
RCA
SceS000003052

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_2931

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga4804 ENSANGP00000010614
Ashbya gossypii (Ago) ago3126 AFL067W
Arabidopsis thaliana (Ath) ath5027 At1g57600.1
Caenorhabditis elegans (Cel) cel21135 ZC101.3
(CE35145;
WBGene00013852)
Candida glabrata (Cgl) cgl2200 CAGL0H03223g
Cryptococcus neoformans (Cne) cne1133 180.m00059
Dictyostelium discoideum (Ddi) ddi8093 DDB0188015
Debaryomyces hansenii (Dha) dha2560 DEHA0D05962g
Drosophila melanogaster (Dme) dme7714 CG11495-PA
(FBgn0024194)
Danio rerio (Dre) dre7771 ENSDARP00000034098
Danio rerio (Dre) dre7773 ENSDARP00000034502
Danio rerio (Dre) dre7772 ENSDARP00000042629
Takifugu rubripes (Fru) fru1908 SINFRUP00000129363
Takifugu rubripes (Fru) fru1909 SINFRUP00000166607
Gallus gallus (Gga) gga14695 ENSGALP00000016046
Gallus gallus (Gga) gga14696 ENSGALP00000016047
(HHAT)
Homo sapiens (Hsa) hsa3010 ENSP00000261458
(HHAT)		 Q5VTY9-1
Homo sapiens (Hsa) hsa3011 ENSP00000308628
(HHAT)		 Q5VTY9-2
Kluyveromyces lactis (Kla) kla3818 KLLA0E19283g
Mus musculus (Mmu) mmu1748 ENSMUSP00000046686
(MGI:2444681)		 Q8BMT9-1
Neurospora crassa (Ncr) ncr2509 NCU02591.2
Oryza sativa (Osa) osa17807 3320.m00089
Rattus norvegicus (Rno) rno9797 ENSRNOP00000005223
Saccharomyces cerevisiae (Sce) sce2178 YGL084C
(S000003052)
Saccharomyces cerevisiae (Sce) sce6351 YPL189W
(S000006110)
Schizosaccharomyces pombe (Spo) spo366 SPAC24H6.01c Q09758
Yarrowia lipolytica (Yli) yli5111 YALI0E30283g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005783 endoplasmic reticulum C
IDA
SceS000003052
GO:0005789 endoplasmic reticulum membrane C
ISS
SpoSPAC24H6.01c
GO:0005829 cytosol C
IDA
SpoSPAC24H6.01c
GO:0005886 plasma membrane C
IDA
SceS000003052
ISS
SpoSPAC24H6.01c
NAS
DmeFBgn0024194
GO:0016020 membrane C
IDA
SceS000003052
ISS
AthAt1g57600
SceS000006110
S000003052
GO:0016021 integral to membrane C
NAS
DmeFBgn0024194
GO:0008374 O-acyltransferase activity F
IMP
SceS000003052
ISS
SceS000006110
SpoSPAC24H6.01c
GO:0008415 acyltransferase activity F
IMP
DmeFBgn0024194
ISS
AthAt1g57600
NAS
DmeFBgn0024194
GO:0016409 palmitoyltransferase activity F
IMP
DmeFBgn0024194
MmuMGI:2444681
GO:0006506 GPI anchor biosynthetic process P
IMP
SceS000003052
ISS
SpoSPAC24H6.01c
GO:0007047 cellular cell wall organization P
RCA
SceS000003052
GO:0007224 smoothened signaling pathway P
IMP
DmeFBgn0024194
MmuMGI:2444681
NAS
DmeFBgn0024194
GO:0007225 patched ligand maturation P
IMP
DmeFBgn0024194
NAS
DmeFBgn0024194
GO:0007367 segment polarity determination P
IMP
DmeFBgn0024194
GO:0008150 biological_process P
ND
AthAt1g57600
GO:0015793 glycerol transport P
IGI
SceS000006110
S000003052
IMP
SceS000003052
ISS
SpoSPAC24H6.01c
GO:0018009 N-terminal peptidyl-L-cysteine
N-palmitoylation		 P
IDA
DmeFBgn0024194
IMP
DmeFBgn0024194
GO:0018318 protein amino acid palmitoylation P
NAS
DmeFBgn0024194
GO:0018345 protein palmitoylation P
IDA
DmeFBgn0024194
IMP
MmuMGI:2444681
GO:0019563 glycerol catabolic process P
IGI
SceS000003052
IMP
SceS000003052
GO:0044262 cellular carbohydrate metabolic
process		 P
RCA
SceS000003052

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPAC24H6.01c
(Q09758)		 YPL189W
(S000006110)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005789 endoplasmic reticulum membrane C
ISS
SpoSPAC24H6.01c
GO:0005829 cytosol C
IDA
SpoSPAC24H6.01c
GO:0005886 plasma membrane C
ISS
SpoSPAC24H6.01c
GO:0016020 membrane C
ISS
SceS000006110
GO:0008374 O-acyltransferase activity F
ISS
SceS000006110
SpoSPAC24H6.01c
GO:0006506 GPI anchor biosynthetic process P
ISS
SpoSPAC24H6.01c
GO:0015793 glycerol transport P
IGI
SceS000006110
ISS
SpoSPAC24H6.01c

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Query species:

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GO info in one table:

s.khadayate@ucl.ac.uk