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Search term: YPL249C


Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name GYP5
SGD link S000006170
Alternative ID YPL249C
Description GTPase-activating protein (GAP) for yeast Rab family members, involved in ER to Golgi trafficking; exhibits GAP activity toward Ypt1p that is stimulated by Gyl1p, also acts on Sec4p; interacts with Gyl1p, Rvs161p and Rvs167p
Synonyms YPL249C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

Search for gene by ID or name:

Query species:

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Search for GO info:  

GO info in one table:


KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG1102 ACDHYPE

KOGs classification KOGs description
POORLY CHARACTERIZED Rab6 GTPase activator GAPCenA and related TBC domain proteins

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At3g02460 GI:6957709
Arabidopsis thaliana (Ath) At5g15930 GI:15237222
Caenorhabditis elegans (Cel) CE27153 GI:17567487
Caenorhabditis elegans (Cel) CE27154 GI:17567489
Caenorhabditis elegans (Cel) CE28983 GI:17537123
Drosophila melanogaster (Dme) 7295111 GI:7295111
Drosophila melanogaster (Dme) 7303241 GI:17737469 Q7KQC4
Homo sapiens (Hsa) Hs12232373 GI:12232373
Homo sapiens (Hsa) Hs14149985
(TBC1D3F)
GI:14149985
Homo sapiens (Hsa) Hs14775809 GI:14775809
Homo sapiens (Hsa) Hs17450832 GI:17450832
Homo sapiens (Hsa) Hs17459099 GI:17459099
Homo sapiens (Hsa) Hs18577228_1 GI:18577228
Homo sapiens (Hsa) Hs18593591_4 GI:18593591
Homo sapiens (Hsa) Hs18603456 GI:18603456
Homo sapiens (Hsa) Hs20478353 GI:20478353
Homo sapiens (Hsa) Hs20479125 GI:20479125
Homo sapiens (Hsa) Hs20557823 GI:20557823
Homo sapiens (Hsa) Hs20560763 GI:20560763
Homo sapiens (Hsa) Hs22043863 GI:22043863
Homo sapiens (Hsa) Hs22046218 GI:22046218
Homo sapiens (Hsa) Hs22046393_1 GI:22046393
Homo sapiens (Hsa) Hs22066444 GI:22066444
Homo sapiens (Hsa) Hs4758564_1 GI:4758564
Homo sapiens (Hsa) Hs7661586 GI:7661586 Q9UFV1
Homo sapiens (Hsa) Hs7661864 GI:7661864 Q96FW8
Homo sapiens (Hsa) Hs7662144 GI:7662144
Saccharomyces cerevisiae (Sce) YMR192w
(S000004804)
GI:6323846 Q04322
Saccharomyces cerevisiae (Sce) YPL249c
(S000006170)
GI:6325007 Q12344
Schizosaccharomyces pombe (Spo) SPAC26F1.09 GI:19115798 Q10496
Schizosaccharomyces pombe (Spo) SPBC1778.09 GI:19113084 Q9Y7J5
Schizosaccharomyces pombe (Spo) SPCC1620.12c GI:19075970 O94419
Encephalitozoon cuniculi (Ecu) ECU11g1700 GI:19074970 Q8SU09
Arabidopsis thaliana (Ath) At3g02460 GI:6957709
Arabidopsis thaliana (Ath) At5g15930 GI:15237222
Caenorhabditis elegans (Cel) CE27153 GI:17567487
Caenorhabditis elegans (Cel) CE27154 GI:17567489
Caenorhabditis elegans (Cel) CE28983 GI:17537123
Drosophila melanogaster (Dme) 7295111 GI:7295111
Drosophila melanogaster (Dme) 7303241 GI:17737469 Q7KQC4
Homo sapiens (Hsa) Hs12232373 GI:12232373
Homo sapiens (Hsa) Hs14149985
(TBC1D3F)
GI:14149985
Homo sapiens (Hsa) Hs14775809 GI:14775809
Homo sapiens (Hsa) Hs17450832 GI:17450832
Homo sapiens (Hsa) Hs17459099 GI:17459099
Homo sapiens (Hsa) Hs18577228_1 GI:18577228
Homo sapiens (Hsa) Hs18593591_4 GI:18593591
Homo sapiens (Hsa) Hs18603456 GI:18603456
Homo sapiens (Hsa) Hs20478353 GI:20478353
Homo sapiens (Hsa) Hs20479125 GI:20479125
Homo sapiens (Hsa) Hs20557823 GI:20557823
Homo sapiens (Hsa) Hs20560763 GI:20560763
Homo sapiens (Hsa) Hs22043863 GI:22043863
Homo sapiens (Hsa) Hs22046218 GI:22046218
Homo sapiens (Hsa) Hs22046393_1 GI:22046393
Homo sapiens (Hsa) Hs22066444 GI:22066444
Homo sapiens (Hsa) Hs4758564_1 GI:4758564
Homo sapiens (Hsa) Hs7661586 GI:7661586 Q9UFV1
Homo sapiens (Hsa) Hs7661864 GI:7661864 Q96FW8
Homo sapiens (Hsa) Hs7662144 GI:7662144
Saccharomyces cerevisiae (Sce) YMR192w
(S000004804)
GI:6323846 Q04322
Saccharomyces cerevisiae (Sce) YPL249c
(S000006170)
GI:6325007 Q12344
Schizosaccharomyces pombe (Spo) SPAC26F1.09 GI:19115798 Q10496
Schizosaccharomyces pombe (Spo) SPBC1778.09 GI:19113084 Q9Y7J5
Schizosaccharomyces pombe (Spo) SPCC1620.12c GI:19075970 O94419
Encephalitozoon cuniculi (Ecu) ECU11g1700 GI:19074970 Q8SU09


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000131 incipient cellular bud site C
IDA
SceS000006170
S000004804
GO:0005624 membrane fraction C
IDA
SceS000006170
GO:0005625 soluble fraction C
IDA
SceS000006170
GO:0005634 nucleus C
IDA
SpoSPCC1620.12c
SPBC1778.09
GO:0005737 cytoplasm C
IDA
SceS000004804
GO:0005739 mitochondrion C
IDA
SceS000004804
GO:0005798 Golgi-associated vesicle C
IDA
SceS000004804
S000006170
ISS
SpoSPAC26F1.09
SPCC1620.12c
GO:0005829 cytosol C
IDA
SceS000006170
SpoSPCC1620.12c
SPAC26F1.09
SPBC1778.09
ISS
SpoSPCC1620.12c
SPAC26F1.09
GO:0005886 plasma membrane C
IDA
SceS000004804
S000006170
ISS
SpoSPAC26F1.09
SPCC1620.12c
GO:0005933 cellular bud C
IDA
SceS000004804
GO:0005934 cellular bud tip C
IDA
SceS000004804
S000006170
GO:0005935 cellular bud neck C
IDA
SceS000004804
S000006170
GO:0005083 small GTPase regulator activity F
RCA
SceS000004804
GO:0005096 GTPase activator activity F
RCA
SceS000004804
GO:0005097 Rab GTPase activator activity F
IGI
SceS000006170
IPI
SceS000006170
ISS
SceS000006170
SpoSPAC26F1.09
SPBC1778.09
SPCC1620.12c
RCA
SceS000004804
GO:0005099 Ras GTPase activator activity F
RCA
SceS000004804
GO:0005515 protein binding F
IPI
SceS000004804
ISS
SceS000004804
GO:0008047 enzyme activator activity F
RCA
SceS000004804
GO:0030234 enzyme regulator activity F
RCA
SceS000004804
GO:0030695 GTPase regulator activity F
RCA
SceS000004804
GO:0060589 nucleoside-triphosphatase regulator
activity
F
RCA
SceS000004804
GO:0000003 reproduction P
RCA
SceS000004804
S000006170
GO:0006888 ER to Golgi vesicle-mediated transport P
IGI
SceS000004804
S000006170
IPI
SceS000004804
S000006170
ISS
SpoSPAC26F1.09
SPCC1620.12c
GO:0016192 vesicle-mediated transport P
IGI
SceS000006170
NAS
SpoSPBC1778.09
GO:0017157 regulation of exocytosis P
IGI
SceS000004804
IPI
SceS000004804
GO:0032313 regulation of Rab GTPase activity P
ISS
SpoSPBC1778.09
SPAC26F1.09
GO:0051049 regulation of transport P
RCA
SceS000006170
GO:0051181 cofactor transport P
RCA
SceS000006170
GO:0051301 cell division P
RCA
SceS000004804
S000006170

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
40396

Species Gene ID NCBI link UniProt link
Saccharomyces cerevisiae (Sce) GYP5
(S000006170)
GI:6325007 Q12344
Kluyveromyces lactis (Kla) KLLA0D12584g GI:50307289
Eremothecium gossypii (Ego) AGOS_AFL161C GI:45198360
Magnaporthe grisea (Mgr) MGG_03253 GI:145608256
Neurospora crassa (Ncr) NCU08499.1 GI:32418132


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000131 incipient cellular bud site C
IDA
SceS000006170
GO:0005624 membrane fraction C
IDA
SceS000006170
GO:0005625 soluble fraction C
IDA
SceS000006170
GO:0005798 Golgi-associated vesicle C
IDA
SceS000006170
GO:0005829 cytosol C
IDA
SceS000006170
GO:0005886 plasma membrane C
IDA
SceS000006170
GO:0005934 cellular bud tip C
IDA
SceS000006170
GO:0005935 cellular bud neck C
IDA
SceS000006170
GO:0005097 Rab GTPase activator activity F
IGI
SceS000006170
IPI
SceS000006170
ISS
SceS000006170
GO:0000003 reproduction P
RCA
SceS000006170
GO:0006888 ER to Golgi vesicle-mediated transport P
IGI
SceS000006170
IPI
SceS000006170
GO:0016192 vesicle-mediated transport P
IGI
SceS000006170
GO:0051049 regulation of transport P
RCA
SceS000006170
GO:0051181 cofactor transport P
RCA
SceS000006170
GO:0051301 cell division P
RCA
SceS000006170

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_357

Species OrthoMCL
sequence
Model organism
protein page
UniProt link
Anopheles gambiae (Aga) aga4517 ENSANGP00000001286
Anopheles gambiae (Aga) aga2758 ENSANGP00000017932
Anopheles gambiae (Aga) aga4518 ENSANGP00000028258
Ashbya gossypii (Ago) ago3034 AFL161C
Arabidopsis thaliana (Ath) ath12261 At3g02460.1
Arabidopsis thaliana (Ath) ath12262 At3g02460.2
Arabidopsis thaliana (Ath) ath23811 At5g15930.1
Caenorhabditis elegans (Cel) cel8209 F35H12.2a
(CE30971;
WBGene00018075)
Caenorhabditis elegans (Cel) cel8210 F35H12.2b
(CE30972)
Caenorhabditis elegans (Cel) cel8211 F35H12.2c
(CE37909)
Caenorhabditis elegans (Cel) cel16247 T24D11.1
(CE39418;
WBGene00020770)
Candida glabrata (Cgl) cgl2096 CAGL0H00737g
Cryptococcus neoformans (Cne) cne3517 176.m02242
Dictyostelium discoideum (Ddi) ddi11730 DDB0185223
Debaryomyces hansenii (Dha) dha4552 DEHA0F03696g
Drosophila melanogaster (Dme) dme17424 CG11727-PA
(FBgn0030299)
Drosophila melanogaster (Dme) dme17425 CG11727-PB
(FBgn0030299)
Drosophila melanogaster (Dme) dme8544 CG7112-PA
(FBgn0035879)
Danio rerio (Dre) dre14586 ENSDARP00000015171
Danio rerio (Dre) dre1038 ENSDARP00000021039
Danio rerio (Dre) dre20456 ENSDARP00000030666
Danio rerio (Dre) dre20454 ENSDARP00000030715
Danio rerio (Dre) dre20455 ENSDARP00000031001
Danio rerio (Dre) dre20477 ENSDARP00000037398
Danio rerio (Dre) dre1039 ENSDARP00000042389
Danio rerio (Dre) dre20476 ENSDARP00000046009
Takifugu rubripes (Fru) fru230 SINFRUP00000128858
Takifugu rubripes (Fru) fru228 SINFRUP00000128859
Takifugu rubripes (Fru) fru229 SINFRUP00000128860
Takifugu rubripes (Fru) fru923 SINFRUP00000163520
Takifugu rubripes (Fru) fru6272 SINFRUP00000164538
Takifugu rubripes (Fru) fru6270 SINFRUP00000167640
Takifugu rubripes (Fru) fru231 SINFRUP00000176772
Takifugu rubripes (Fru) fru6271 SINFRUP00000176869
Gallus gallus (Gga) gga7823 ENSGALP00000001856
(RABGAP1)
Gallus gallus (Gga) gga7824 ENSGALP00000001857
Gallus gallus (Gga) gga22350 ENSGALP00000007274
(RCJMB04_21k9)
Gallus gallus (Gga) gga22494 ENSGALP00000009538
(EVI5)
Gallus gallus (Gga) gga22495 ENSGALP00000009539
Homo sapiens (Hsa) hsa2640 ENSP00000251507
(RABGAP1L)
Q5R372-1
Homo sapiens (Hsa) hsa15507 ENSP00000270530
(EVI5L)
Q96CN4
Homo sapiens (Hsa) hsa31870 ENSP00000344404
Homo sapiens (Hsa) hsa1502 ENSP00000345500
(EVI5)
Q59FE7
Homo sapiens (Hsa) hsa2641 ENSP00000355139
Kluyveromyces lactis (Kla) kla2622 KLLA0D12584g
Mus musculus (Mmu) mmu20551 ENSMUSP00000011975
(MGI:104736)
Q3UYX4
Mus musculus (Mmu) mmu1316 ENSMUSP00000028049
(MGI:1352507)
A6H6A9-1
Mus musculus (Mmu) mmu25559 ENSMUSP00000049266
(MGI:2442167)
Q3U1G0
Mus musculus (Mmu) mmu14552 ENSMUSP00000068835
(MGI:2385139)
A2AWA9-2
Neurospora crassa (Ncr) ncr6181 NCU06362.2
Neurospora crassa (Ncr) ncr8281 NCU08499.2
Oryza sativa (Osa) osa71781 7205.m00147
Rattus norvegicus (Rno) rno7909 ENSRNOP00000001367
Rattus norvegicus (Rno) rno9906 ENSRNOP00000002788
Rattus norvegicus (Rno) rno9351 ENSRNOP00000003671
(RGD:1304620)
Rattus norvegicus (Rno) rno18543 ENSRNOP00000013378
(RGD:1304691)
Saccharomyces cerevisiae (Sce) sce6412 YPL249C
(S000006170)
Schizosaccharomyces pombe (Spo) spo1634 SPAC26F1.09 Q10496
Yarrowia lipolytica (Yli) yli1233 YALI0B11946g
Yarrowia lipolytica (Yli) yli6101 YALI0F18106g