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Search term: YPL268W


Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name PLC1
SGD link S000006189
Alternative ID YPL268W
Description Phospholipase C, hydrolyzes phosphatidylinositol 4,5-biphosphate (PIP2) to generate the signaling molecules inositol 1,4,5-triphosphate (IP3) and 1,2-diacylglycerol (DAG); involved in regulating many cellular processes
Synonyms YPL268W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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Query species:

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GO info in one table:


KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG0169 AC-HYP-

KOGs classification KOGs description
CELLULAR PROCESSES AND SIGNALING Phosphoinositide-specific phospholipase C

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At3g08510 GI:15231929
Arabidopsis thaliana (Ath) At3g47220 GI:15232750
Arabidopsis thaliana (Ath) At3g47290 GI:15232770
Arabidopsis thaliana (Ath) At3g55940 GI:15228780
Arabidopsis thaliana (Ath) At4g38530 GI:15233918
Arabidopsis thaliana (Ath) At5g58670 GI:15237728
Arabidopsis thaliana (Ath) At5g58690 GI:15237732
Arabidopsis thaliana (Ath) At5g58700 GI:15237734
Caenorhabditis elegans (Cel) CE07421
(WBGene00004039)
GI:17541792 Q21754
Caenorhabditis elegans (Cel) CE12090 GI:17554140
Homo sapiens (Hsa) Hs14249340
(PLCD4)
GI:14249340 Q9BRC7
Homo sapiens (Hsa) Hs14731274 GI:14731274
Homo sapiens (Hsa) Hs14916457 GI:14916457
Homo sapiens (Hsa) Hs19115964
(PLCD3)
GI:19115964 Q8N3E9
Homo sapiens (Hsa) Hs20475709 GI:20475709
Homo sapiens (Hsa) Hs22043164 GI:22043164
Homo sapiens (Hsa) Hs5453910 GI:5453910
Homo sapiens (Hsa) Hs5453912 GI:5453912
Saccharomyces cerevisiae (Sce) YPL268w
(S000006189)
GI:6324987 P32383
Schizosaccharomyces pombe (Spo) SPAC22F8.11 GI:19115646 P40977
Arabidopsis thaliana (Ath) At3g08510 GI:15231929
Arabidopsis thaliana (Ath) At3g47220 GI:15232750
Arabidopsis thaliana (Ath) At3g47290 GI:15232770
Arabidopsis thaliana (Ath) At3g55940 GI:15228780
Arabidopsis thaliana (Ath) At4g38530 GI:15233918
Arabidopsis thaliana (Ath) At5g58670 GI:15237728
Arabidopsis thaliana (Ath) At5g58690 GI:15237732
Arabidopsis thaliana (Ath) At5g58700 GI:15237734
Caenorhabditis elegans (Cel) CE07421
(WBGene00004039)
GI:17541792 Q21754
Caenorhabditis elegans (Cel) CE12090 GI:17554140
Homo sapiens (Hsa) Hs14249340
(PLCD4)
GI:14249340 Q9BRC7
Homo sapiens (Hsa) Hs14731274 GI:14731274
Homo sapiens (Hsa) Hs14916457 GI:14916457
Homo sapiens (Hsa) Hs19115964
(PLCD3)
GI:19115964 Q8N3E9
Homo sapiens (Hsa) Hs20475709 GI:20475709
Homo sapiens (Hsa) Hs22043164 GI:22043164
Homo sapiens (Hsa) Hs5453910 GI:5453910
Homo sapiens (Hsa) Hs5453912 GI:5453912
Saccharomyces cerevisiae (Sce) YPL268w
(S000006189)
GI:6324987 P32383
Schizosaccharomyces pombe (Spo) SPAC22F8.11 GI:19115646 P40977
Arabidopsis thaliana (Ath) At3g08510 GI:15231929
Arabidopsis thaliana (Ath) At3g47220 GI:15232750
Arabidopsis thaliana (Ath) At3g47290 GI:15232770
Arabidopsis thaliana (Ath) At3g55940 GI:15228780
Arabidopsis thaliana (Ath) At4g38530 GI:15233918
Arabidopsis thaliana (Ath) At5g58670 GI:15237728
Arabidopsis thaliana (Ath) At5g58690 GI:15237732
Arabidopsis thaliana (Ath) At5g58700 GI:15237734
Caenorhabditis elegans (Cel) CE07421
(WBGene00004039)
GI:17541792 Q21754
Caenorhabditis elegans (Cel) CE12090 GI:17554140
Homo sapiens (Hsa) Hs14249340
(PLCD4)
GI:14249340 Q9BRC7
Homo sapiens (Hsa) Hs14731274 GI:14731274
Homo sapiens (Hsa) Hs14916457 GI:14916457
Homo sapiens (Hsa) Hs19115964
(PLCD3)
GI:19115964 Q8N3E9
Homo sapiens (Hsa) Hs20475709 GI:20475709
Homo sapiens (Hsa) Hs22043164 GI:22043164
Homo sapiens (Hsa) Hs5453910 GI:5453910
Homo sapiens (Hsa) Hs5453912 GI:5453912
Saccharomyces cerevisiae (Sce) YPL268w
(S000006189)
GI:6324987 P32383
Schizosaccharomyces pombe (Spo) SPAC22F8.11 GI:19115646 P40977


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000775 chromosome, centromeric region C
IDA
SceS000006189
GO:0000778 condensed nuclear chromosome kinetochore C
IPI
SceS000006189
GO:0005575 cellular_component C
ND
AthAt5g58690
At4g38530
At5g58670
GO:0005634 nucleus C
IDA
SpoSPAC22F8.11
ISS
SpoSPAC22F8.11
GO:0005737 cytoplasm C
IDA
SpoSPAC22F8.11
GO:0005829 cytosol C
IDA
SpoSPAC22F8.11
GO:0005886 plasma membrane C
IDA
AthAt3g55940
At3g08510
At5g58700
GO:0004435 phosphoinositide phospholipase C
activity
F
IDA
SceS000006189
IMP
SceS000006189
ISS
AthAt3g47220
At5g58700
TAS
SpoSPAC22F8.11
GO:0004629 phospholipase C activity F
IDA
AthAt5g58670
ISS
AthAt3g55940
At4g38530
At3g47290
At5g58690
At5g58670
TAS
AthAt3g08510
At5g58670
GO:0005509 calcium ion binding F
ISS
SpoSPAC22F8.11
GO:0005515 protein binding F
IPI
SpoSPAC22F8.11
GO:0000003 reproduction P
IMP
CelWBGene00004039
GO:0001402 signal transduction involved in filamentous
growth
P
IGI
SceS000006189
IPI
SceS000006189
GO:0006629 lipid metabolic process P
ISS
AthAt5g58700
At3g47220
GO:0007165 signal transduction P
ISS
AthAt3g55940
At4g38530
At3g47220
At3g08510
At3g47290
At5g58690
At5g58700
At5g58670
SpoSPAC22F8.11
GO:0009395 phospholipid catabolic process P
IDA
SceS000006189
IMP
SceS000006189
GO:0009409 response to cold P
IEP
AthAt5g58670
GO:0009414 response to water deprivation P
IEP
AthAt5g58670
GO:0009651 response to salt stress P
IEP
AthAt5g58670
GO:0009737 response to abscisic acid stimulus P
IMP
AthAt5g58670
GO:0009738 abscisic acid mediated signaling
pathway
P
TAS
AthAt5g58670
GO:0019220 regulation of phosphate metabolic
process
P
ISS
SpoSPAC22F8.11
GO:0023034 intracellular signaling pathway P
ISS
AthAt3g47290
At5g58700
At3g47220
GO:0032958 inositol phosphate biosynthetic
process
P
IMP
SceS000006189
GO:0034501 protein localization to kinetochore P
IMP
SceS000006189
GO:0034644 cellular response to UV P
IMP
SpoSPAC22F8.11
GO:0044242 cellular lipid catabolic process P
IC
SpoSPAC22F8.11
GO:0048017 inositol lipid-mediated signaling P
IC
SpoSPAC22F8.11

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
88782

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) PLCD4 GI:14249340 Q9BRC7
Pan troglodytes (Ptr) PLCD4 GI:114583338
Canis familiaris (Cfa) PLCD4 GI:74005733
Mus musculus (Mmu) Plcd4
(MGI:107469)
GI:125347158 Q8K3R3
Rattus norvegicus (Rno) Plcd4
(RGD:621025)
GI:18093100
Schizosaccharomyces pombe (Spo) plc1
(SPAC22F8.11)
GI:19115646 P40977
Saccharomyces cerevisiae (Sce) PLC1
(S000006189)
GI:6324987 P32383
Kluyveromyces lactis (Kla) KLLA0D00638g GI:50306257
Eremothecium gossypii (Ego) AGOS_ACR024W GI:45185711
Magnaporthe grisea (Mgr) MGG_02444 GI:145606240
Neurospora crassa (Ncr) NCU01266.1 GI:32412558
Arabidopsis thaliana (Ath) AT2G40116 GI:42570393


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000775 chromosome, centromeric region C
IDA
SceS000006189
GO:0000778 condensed nuclear chromosome kinetochore C
IPI
SceS000006189
GO:0005575 cellular_component C
ND
AthAT2G40116
GO:0005622 intracellular C
IDA
MmuMGI:107469
GO:0005634 nucleus C
IDA
SpoSPAC22F8.11
ISS
SpoSPAC22F8.11
GO:0005737 cytoplasm C
IDA
SpoSPAC22F8.11
GO:0005829 cytosol C
IDA
SpoSPAC22F8.11
GO:0004435 phosphoinositide phospholipase C
activity
F
IDA
SceS000006189
IMP
SceS000006189
ISO
MmuMGI:107469
ISS
AthAT2G40116
TAS
SpoSPAC22F8.11
GO:0004629 phospholipase C activity F
TAS
MmuMGI:107469
GO:0005509 calcium ion binding F
ISS
SpoSPAC22F8.11
GO:0005515 protein binding F
IPI
SpoSPAC22F8.11
GO:0001402 signal transduction involved in filamentous
growth
P
IGI
SceS000006189
IPI
SceS000006189
GO:0006629 lipid metabolic process P
ISS
AthAT2G40116
GO:0007165 signal transduction P
ISS
AthAT2G40116
SpoSPAC22F8.11
TAS
MmuMGI:107469
GO:0007340 acrosome reaction P
IMP
MmuMGI:107469
GO:0009395 phospholipid catabolic process P
IDA
SceS000006189
IMP
SceS000006189
GO:0019220 regulation of phosphate metabolic
process
P
ISS
SpoSPAC22F8.11
GO:0023034 intracellular signaling pathway P
ISS
AthAT2G40116
GO:0030384 phosphoinositide metabolic process P
TAS
MmuMGI:107469
GO:0032958 inositol phosphate biosynthetic
process
P
IMP
SceS000006189
GO:0034501 protein localization to kinetochore P
IMP
SceS000006189
GO:0034644 cellular response to UV P
IMP
SpoSPAC22F8.11
GO:0044242 cellular lipid catabolic process P
IC
SpoSPAC22F8.11
GO:0048017 inositol lipid-mediated signaling P
IC
SpoSPAC22F8.11

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_567

Species OrthoMCL
sequence
Model organism
protein page
UniProt link
Ashbya gossypii (Ago) ago1072 ACR024W
Arabidopsis thaliana (Ath) ath11142 At2g40116.1
Arabidopsis thaliana (Ath) ath16983 At3g55940.1
Arabidopsis thaliana (Ath) ath22048 At4g38530.1
Arabidopsis thaliana (Ath) ath27923 At5g58670.1
Arabidopsis thaliana (Ath) ath27925 At5g58690.1
Caenorhabditis elegans (Cel) cel13381 R05G6.8
(CE07421;
WBGene00004039)
Candida glabrata (Cgl) cgl47 CAGL0A01177g
Cryptococcus neoformans (Cne) cne5556 179.m00415
Dictyostelium discoideum (Ddi) ddi13364 DDB0201656
Debaryomyces hansenii (Dha) dha202 DEHA0A04554g
Danio rerio (Dre) dre17257 ENSDARP00000025899
Danio rerio (Dre) dre23952 ENSDARP00000039732
Danio rerio (Dre) dre14242 ENSDARP00000040344
Danio rerio (Dre) dre23951 ENSDARP00000044037
Danio rerio (Dre) dre3056 ENSDARP00000045773
Danio rerio (Dre) dre3057 ENSDARP00000047119
Takifugu rubripes (Fru) fru23622 SINFRUP00000128724
Takifugu rubripes (Fru) fru8775 SINFRUP00000137912
Takifugu rubripes (Fru) fru20879 SINFRUP00000140654
Takifugu rubripes (Fru) fru16313 SINFRUP00000161709
Takifugu rubripes (Fru) fru8777 SINFRUP00000173210
Takifugu rubripes (Fru) fru16314 SINFRUP00000174868
Takifugu rubripes (Fru) fru8776 SINFRUP00000176951
Gallus gallus (Gga) gga9342 ENSGALP00000009307
(PLCD1)
Gallus gallus (Gga) gga9343 ENSGALP00000009308
(PLCD1)
Homo sapiens (Hsa) hsa19284 ENSP00000251959
(PLCD4)
C9JEA7
Homo sapiens (Hsa) hsa13840 ENSP00000313731
(PLCD3)
Q8N3E9
Homo sapiens (Hsa) hsa22250 ENSP00000335600
(PLCD1)
P51178
Homo sapiens (Hsa) hsa13839 ENSP00000350938
Kluyveromyces lactis (Kla) kla2099 KLLA0D00638g
Mus musculus (Mmu) mmu28450 ENSMUSP00000010804
(MGI:97614)
Q9Z1B4
Mus musculus (Mmu) mmu4936 ENSMUSP00000021320
(MGI:107451)
Q8K2J0
Mus musculus (Mmu) mmu553 ENSMUSP00000027362
(MGI:107469)
Q8K3R3-1
Mus musculus (Mmu) mmu552 ENSMUSP00000064413
(MGI:107469)
Q8K3R3-3
Neurospora crassa (Ncr) ncr1228 NCU01266.2
Neurospora crassa (Ncr) ncr2117 NCU02175.2
Neurospora crassa (Ncr) ncr6070 NCU06245.2
Oryza sativa (Osa) osa3475 2031.m00097
Oryza sativa (Osa) osa58866 6472.m00117
Oryza sativa (Osa) osa68820 7028.m00131
Oryza sativa (Osa) osa78375 7491.m00127
Plasmodium falciparum (Pfa) pfa353 PF10_0132
Rattus norvegicus (Rno) rno6241 ENSRNOP00000004140
(RGD:1310903)
Rattus norvegicus (Rno) rno30243 ENSRNOP00000022234
(RGD:621025)
Q62711-2
Rattus norvegicus (Rno) rno30244 ENSRNOP00000039708
(RGD:621025)
Q62711-1
Rattus norvegicus (Rno) rno29438 ENSRNOP00000042824
(RGD:3346)
P10688
Rattus norvegicus (Rno) rno6240 ENSRNOP00000051398
Saccharomyces cerevisiae (Sce) sce6435 YPL268W
(S000006189)
Schizosaccharomyces pombe (Spo) spo2251 SPAC22F8.11 P40977
Yarrowia lipolytica (Yli) yli1888 YALI0C04180g