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Search term: YPR021C

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name AGC1
SGD link S000006225
Alternative ID YPR021C
Description Mitochondrial amino acid transporter, acts both as a glutamate uniporter and as an aspartate-glutamate exchanger; involved in nitrogen metabolism and nitrogen compound biosynthesis
Synonyms YPR021C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG0751 -CDHY--

KOGs classification KOGs description
METABOLISM Mitochondrial aspartate/glutamate carrier protein Aralar/Citrin (contains EF-hand Ca2+-binding domains)

Species KOG link NCBI link UniProt link
Homo sapiens (Hsa) Hs21361103 GI:14747216
Caenorhabditis elegans (Cel) CE01348 GI:17554004
Drosophila melanogaster (Dme) 7301942 GI:13124102
Drosophila melanogaster (Dme) 7301944 GI:7301944
Homo sapiens (Hsa) HsM4507007 GI:4507007
Homo sapiens (Hsa) Hs7657581
(SLC25A13)		 GI:7657581 Q9UJS0
Saccharomyces cerevisiae (Sce) YPR021c
(S000006225)		 GI:6325278 Q12482
Homo sapiens (Hsa) Hs21361103 GI:14747216
Caenorhabditis elegans (Cel) CE01348 GI:17554004
Drosophila melanogaster (Dme) 7301942 GI:13124102
Drosophila melanogaster (Dme) 7301944 GI:7301944
Homo sapiens (Hsa) HsM4507007 GI:4507007
Homo sapiens (Hsa) Hs7657581
(SLC25A13)		 GI:7657581 Q9UJS0
Saccharomyces cerevisiae (Sce) YPR021c
(S000006225)		 GI:6325278 Q12482


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005739 mitochondrion C
IDA
HsaSLC25A13
SceS000006225
GO:0005743 mitochondrial inner membrane C
ISS
HsaSLC25A13
SceS000006225
GO:0005887 integral to plasma membrane C
NAS
HsaSLC25A13
GO:0005215 transporter activity F
NAS
HsaSLC25A13
GO:0005313 L-glutamate transmembrane transporter
activity		 F
IDA
HsaSLC25A13
SceS000006225
GO:0005509 calcium ion binding F
IDA
HsaSLC25A13
GO:0015183 L-aspartate transmembrane transporter
activity		 F
IDA
HsaSLC25A13
SceS000006225
GO:0015292 uniporter activity F
IDA
SceS000006225
GO:0015297 antiporter activity F
IDA
SceS000006225
GO:0006754 ATP biosynthetic process P
IDA
HsaSLC25A13
GO:0006810 transport P
NAS
HsaSLC25A13
GO:0015810 aspartate transport P
IDA
HsaSLC25A13
SceS000006225
GO:0015813 L-glutamate transport P
IDA
HsaSLC25A13
SceS000006225
GO:0043490 malate-aspartate shuttle P
IDA
HsaSLC25A13
GO:0044271 cellular nitrogen compound biosynthetic
process		 P
IMP
SceS000006225
GO:0045333 cellular respiration P
IDA
HsaSLC25A13
GO:0051592 response to calcium ion P
IDA
HsaSLC25A13

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
68975

Species Gene ID NCBI link UniProt link
Saccharomyces cerevisiae (Sce) AGC1
(S000006225)		 GI:6325278 Q12482
Kluyveromyces lactis (Kla) KLLA0E13453g GI:50309099
Eremothecium gossypii (Ego) AGOS_ADL049W GI:45187824


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005739 mitochondrion C
IDA
SceS000006225
GO:0005743 mitochondrial inner membrane C
ISS
SceS000006225
GO:0005313 L-glutamate transmembrane transporter
activity		 F
IDA
SceS000006225
GO:0015183 L-aspartate transmembrane transporter
activity		 F
IDA
SceS000006225
GO:0015292 uniporter activity F
IDA
SceS000006225
GO:0015297 antiporter activity F
IDA
SceS000006225
GO:0015810 aspartate transport P
IDA
SceS000006225
GO:0015813 L-glutamate transport P
IDA
SceS000006225
GO:0044271 cellular nitrogen compound biosynthetic
process		 P
IMP
SceS000006225

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_2558

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga15664 ENSANGP00000018542
Ashbya gossypii (Ago) ago1692 ADL049W
Caenorhabditis elegans (Cel) cel11705 K02F3.2
(CE39385;
WBGene00019326)
Candida glabrata (Cgl) cgl3623 CAGL0K02365g
Cryptococcus neoformans (Cne) cne5393 179.m00245
Dictyostelium discoideum (Ddi) ddi4974 DDB0218474
Debaryomyces hansenii (Dha) dha2105 DEHA0C15268g
Drosophila melanogaster (Dme) dme15226 CG2139-PA
(FBgn0028646)
Drosophila melanogaster (Dme) dme15225 CG2139-PB
(FBgn0028646)
Drosophila melanogaster (Dme) dme15224 CG2139-PC
(FBgn0028646)
Drosophila melanogaster (Dme) dme15227 CG2139-PD
(FBgn0028646)
Danio rerio (Dre) dre27394 ENSDARP00000012050
Danio rerio (Dre) dre22216 ENSDARP00000023157
Takifugu rubripes (Fru) fru193 SINFRUP00000149390
Takifugu rubripes (Fru) fru192 SINFRUP00000149396
Takifugu rubripes (Fru) fru10689 SINFRUP00000155578
Takifugu rubripes (Fru) fru194 SINFRUP00000167163
Gallus gallus (Gga) gga21527 ENSGALP00000015517
(SLC25A13)		 Q5ZIF4
Gallus gallus (Gga) gga21526 ENSGALP00000015519
(SLC25A12)
Gallus gallus (Gga) gga9746 ENSGALP00000015817
(SLC25A13)
Homo sapiens (Hsa) hsa18860 ENSP00000263812
(SLC25A12)		 C9JI53
Homo sapiens (Hsa) hsa28997 ENSP00000265631
(SLC25A13)		 Q9UJS0
Kluyveromyces lactis (Kla) kla3554 KLLA0E13453g
Mus musculus (Mmu) mmu21417 ENSMUSP00000015256
(MGI:1354721)		 Q9QXX4
Mus musculus (Mmu) mmu14762 ENSMUSP00000028396
(MGI:1926080)		 Q8BH59
Neurospora crassa (Ncr) ncr1203 NCU01241.2
Rattus norvegicus (Rno) rno20810 ENSRNOP00000013816
(RGD:1565889)
Saccharomyces cerevisiae (Sce) sce6475 YPR021C
(S000006225)
Yarrowia lipolytica (Yli) yli3804 YALI0D26147g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005739 mitochondrion C
IDA
MmuMGI:1926080
MGI:1354721
SceS000006225
IMP
MmuMGI:1926080
MGI:1354721
GO:0005740 mitochondrial envelope C
ISS
DmeFBgn0028646
GO:0005743 mitochondrial inner membrane C
IDA
MmuMGI:1926080
MGI:1354721
ISS
DmeFBgn0028646
SceS000006225
NAS
DmeFBgn0028646
TAS
MmuMGI:1926080
MGI:1354721
GO:0005811 lipid particle C
IDA
DmeFBgn0028646
GO:0016021 integral to membrane C
NAS
DmeFBgn0028646
GO:0005313 L-glutamate transmembrane transporter
activity		 F
IDA
SceS000006225
IMP
MmuMGI:1354721
GO:0005509 calcium ion binding F
ISS
DmeFBgn0028646
NAS
DmeFBgn0028646
GO:0015183 L-aspartate transmembrane transporter
activity		 F
IDA
SceS000006225
GO:0015292 uniporter activity F
IDA
SceS000006225
GO:0015297 antiporter activity F
IDA
SceS000006225
GO:0022857 transmembrane transporter activity F
ISS
DmeFBgn0028646
NAS
DmeFBgn0028646
GO:0000003 reproduction P
IMP
CelWBGene00019326
GO:0003333 amino acid transmembrane transport P
IMP
MmuMGI:1354721
GO:0006810 transport P
NAS
DmeFBgn0028646
GO:0006839 mitochondrial transport P
ISS
DmeFBgn0028646
GO:0015807 L-amino acid transport P
IMP
MmuMGI:1354721
GO:0015810 aspartate transport P
IDA
SceS000006225
IMP
MmuMGI:1354721
GO:0015813 L-glutamate transport P
IDA
SceS000006225
IMP
MmuMGI:1354721
GO:0043490 malate-aspartate shuttle P
IMP
MmuMGI:1926080
MGI:1354721
GO:0044271 cellular nitrogen compound biosynthetic
process		 P
IMP
SceS000006225

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