Search term: YPR025C

Gene summary:

KOG results:

KOG name	Phylogenetic pattern (and link to KOGs with this pattern)
KOG2496	ACDHYP-

KOGs classification	KOGs description
CELLULAR PROCESSES AND SIGNALINGINFORMATION STORAGE AND PROCESSINGINFORMATION STORAGE AND PROCESSING	Cdk activating kinase (CAK)/RNA polymerase II transcription initiation/nucleotide excision repair factor TFIIH/TFIIK, cyclin H subunit

Species	KOG link	NCBI link	UniProt link
Arabidopsis thaliana (Ath)	At5g27620	GI:15241008
Caenorhabditis elegans (Cel)	CE25333	GI:17537285
Drosophila melanogaster (Dme)	7296498 (FBgn0022936)	GI:17737725	O76513
Homo sapiens (Hsa)	Hs4502623 (CCNH)	GI:4502623	P51946
Homo sapiens (Hsa)	Hs18556907	GI:18556907
Saccharomyces cerevisiae (Sce)	YPR025c (S000006229)	GI:6325282	P37366
Schizosaccharomyces pombe (Spo)	SPBP16F5.02	GI:19112568	P36613

GO terms for KOG results:

GO ID	GO term	GO aspect	Evidence codes and associations
GO:0000109	nucleotide-excision repair complex	C	RCA Sce S000006229
GO:0005634	nucleus	C	IDA Ath At5g27620 Spo SPBP16F5.02
GO:0005654	nucleoplasm	C	EXP Hsa CCNH
GO:0005675	holo TFIIH complex	C	IDA Hsa CCNH Sce S000006229 ISS Dme FBgn0022936 Spo SPBP16F5.02
GO:0005737	cytoplasm	C	IDA Ath At5g27620
GO:0005739	mitochondrion	C	IDA Sce S000006229
GO:0019907	cyclin-dependent protein kinase activating kinase holoenzyme complex	C	IDA Hsa CCNH
GO:0070985	TFIIK complex	C	IDA Sce S000006229
GO:0004672	protein kinase activity	F	IDA Ath At5g27620 Hsa CCNH
GO:0004693	cyclin-dependent protein kinase activity	F	ISS Ath At5g27620
GO:0004861	cyclin-dependent protein kinase inhibitor activity	F	IGI Spo SPBP16F5.02
GO:0005515	protein binding	F	IPI Ath At5g27620 Hsa CCNH Spo SPBP16F5.02
GO:0008094	DNA-dependent ATPase activity	F	IDA Hsa CCNH
GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity	F	IDA Hsa CCNH
GO:0016251	general RNA polymerase II transcription factor activity	F	IDA Sce S000006229 ISS Dme FBgn0022936
GO:0016538	cyclin-dependent protein kinase regulator activity	F	ISS Dme FBgn0022936
GO:0000079	regulation of cyclin-dependent protein kinase activity	P	NAS Spo SPBP16F5.02
GO:0000718	nucleotide-excision repair, DNA damage removal	P	EXP Hsa CCNH
GO:0006366	transcription from RNA polymerase II promoter	P	IDA Hsa CCNH
GO:0006367	transcription initiation from RNA polymerase II promoter	P	EXP Hsa CCNH ISS Dme FBgn0022936 Spo SPBP16F5.02
GO:0006368	RNA elongation from RNA polymerase II promoter	P	EXP Hsa CCNH
GO:0007346	regulation of mitotic cell cycle	P	IGI Spo SPBP16F5.02
GO:0032568	general transcription from RNA polymerase II promoter	P	IDA Sce S000006229
GO:0042326	negative regulation of phosphorylation	P	IGI Spo SPBP16F5.02
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	P	IDA Hsa CCNH
GO:0051726	regulation of cell cycle	P	ISS Ath At5g27620
GO:0070816	phosphorylation of RNA polymerase II C-terminal domain	P	IDA Sce S000006229

HomoloGene results:

HomoloGene cluster	Phylogenetic pattern
946

Species	Gene ID	NCBI link	UniProt link
Homo sapiens (Hsa)	CCNH	GI:4502623	P51946
Pan troglodytes (Ptr)	CCNH	GI:114599281
Canis familiaris (Cfa)	CCNH	GI:73952310
Mus musculus (Mmu)	Ccnh (MGI:1913921)	GI:12963599	Q3UUW5
Rattus norvegicus (Rno)	Ccnh (RGD:69419)	GI:31542350	45594
Gallus gallus (Gga)	CCNH	GI:118104376
Drosophila melanogaster (Dme)	CycH (FBgn0022936)	GI:17737725	O76513
Anopheles gambiae (Aga)	AgaP_AGAP008417	GI:158296679
Caenorhabditis elegans (Cel)	cyh-1 (CE36037; WBGene00021714)	GI:71998326
Schizosaccharomyces pombe (Spo)	mcs2 (SPBP16F5.02)	GI:19112568	P36613
Saccharomyces cerevisiae (Sce)	CCL1 (S000006229)	GI:6325282	P37366
Kluyveromyces lactis (Kla)	KLLA0E06666g	GI:50308495
Eremothecium gossypii (Ego)	AGOS_AGL273C	GI:45200824
Arabidopsis thaliana (Ath)	CYCH;1	GI:22327103
Oryza sativa (Osa)	Os03g0737600	GI:115455205

GO terms for Homologene results:

GO ID	GO term	GO aspect	Evidence codes and associations
GO:0000109	nucleotide-excision repair complex	C	RCA Sce S000006229
GO:0005634	nucleus	C	IDA Ath CYCH;1 Mmu MGI:1913921 Spo SPBP16F5.02
GO:0005654	nucleoplasm	C	EXP Hsa CCNH
GO:0005675	holo TFIIH complex	C	IDA Hsa CCNH Sce S000006229 ISS Dme FBgn0022936 Spo SPBP16F5.02
GO:0005737	cytoplasm	C	IDA Ath CYCH;1
GO:0005739	mitochondrion	C	IDA Sce S000006229
GO:0019907	cyclin-dependent protein kinase activating kinase holoenzyme complex	C	IDA Hsa CCNH
GO:0070985	TFIIK complex	C	IDA Sce S000006229
GO:0004672	protein kinase activity	F	IDA Ath CYCH;1 Hsa CCNH
GO:0004693	cyclin-dependent protein kinase activity	F	ISS Ath CYCH;1 Mmu MGI:1913921
GO:0004861	cyclin-dependent protein kinase inhibitor activity	F	IGI Spo SPBP16F5.02
GO:0005515	protein binding	F	IPI Ath CYCH;1 Hsa CCNH Spo SPBP16F5.02
GO:0008094	DNA-dependent ATPase activity	F	IDA Hsa CCNH
GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity	F	IDA Hsa CCNH
GO:0016251	general RNA polymerase II transcription factor activity	F	IDA Sce S000006229 ISS Dme FBgn0022936
GO:0016301	kinase activity	F	IDA Mmu MGI:1913921
GO:0016538	cyclin-dependent protein kinase regulator activity	F	ISS Dme FBgn0022936
GO:0000003	reproduction	P	IMP Cel WBGene00021714
GO:0000079	regulation of cyclin-dependent protein kinase activity	P	NAS Spo SPBP16F5.02
GO:0000718	nucleotide-excision repair, DNA damage removal	P	EXP Hsa CCNH
GO:0002009	morphogenesis of an epithelium	P	IMP Cel WBGene00021714
GO:0002119	nematode larval development	P	IMP Cel WBGene00021714
GO:0006366	transcription from RNA polymerase II promoter	P	IDA Hsa CCNH
GO:0006367	transcription initiation from RNA polymerase II promoter	P	EXP Hsa CCNH ISS Dme FBgn0022936 Spo SPBP16F5.02
GO:0006368	RNA elongation from RNA polymerase II promoter	P	EXP Hsa CCNH
GO:0007049	cell cycle	P	ISS Mmu MGI:1913921
GO:0007346	regulation of mitotic cell cycle	P	IGI Spo SPBP16F5.02
GO:0009792	embryo development ending in birth or egg hatching	P	IMP Cel WBGene00021714
GO:0010171	body morphogenesis	P	IMP Cel WBGene00021714
GO:0016310	phosphorylation	P	IDA Mmu MGI:1913921 ISS Mmu MGI:1913921
GO:0032568	general transcription from RNA polymerase II promoter	P	IDA Sce S000006229
GO:0040007	growth	P	IMP Cel WBGene00021714
GO:0040010	positive regulation of growth rate	P	IMP Cel WBGene00021714
GO:0040011	locomotion	P	IMP Cel WBGene00021714
GO:0040035	hermaphrodite genitalia development	P	IMP Cel WBGene00021714
GO:0042326	negative regulation of phosphorylation	P	IGI Spo SPBP16F5.02
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	P	IDA Hsa CCNH
GO:0051726	regulation of cell cycle	P	ISS Ath CYCH;1
GO:0070816	phosphorylation of RNA polymerase II C-terminal domain	P	IDA Sce S000006229

OrthoMCL results:

OrthoMCL cluster	Phylogenetic pattern
OG1_4043

Species	OrthoMCL sequence	Model organism protein page	UniProt link
Anopheles gambiae (Aga)	aga10420	ENSANGP00000019240
Ashbya gossypii (Ago)	ago4039	AGL273C
Arabidopsis thaliana (Ath)	ath25036	At5g27620.1
Caenorhabditis elegans (Cel)	cel19371	Y49F6B.1 (CE36037; WBGene00021714)
Candida glabrata (Cgl)	cgl3744	CAGL0K05115g
Cryptococcus neoformans (Cne)	cne234	162.m02705
Dictyostelium discoideum (Ddi)	ddi13674	DDB0231776
Debaryomyces hansenii (Dha)	dha832	DEHA0B03366g
Drosophila melanogaster (Dme)	dme10667	CG7405-PA (FBgn0022936)
Danio rerio (Dre)	dre19780	ENSDARP00000004735 (zgc:114132)	Q5BJA4
Takifugu rubripes (Fru)	fru19682	SINFRUP00000142883
Gallus gallus (Gga)	gga28025	ENSGALP00000025170 (CCNH)
Homo sapiens (Hsa)	hsa25482	ENSP00000256897 (CCNH)	P51946
Kluyveromyces lactis (Kla)	kla3248	KLLA0E06666g
Mus musculus (Mmu)	mmu7325	ENSMUSP00000022030 (MGI:1913921)	Q3UUW5
Neurospora crassa (Ncr)	ncr1031	NCU01067.2
Oryza sativa (Osa)	osa64752	6714.m00136
Rattus norvegicus (Rno)	rno15298	ENSRNOP00000039039 (RGD:69419)	Q9R1A0
Saccharomyces cerevisiae (Sce)	sce6479	YPR025C (S000006229)
Schizosaccharomyces pombe (Spo)	spo1429	SPBP16F5.02	P36613
Yarrowia lipolytica (Yli)	yli234	YALI0A06996g

GO terms for OrthoMCL results:

GO ID	GO term	GO aspect	Evidence codes and associations
GO:0000109	nucleotide-excision repair complex	C	RCA Sce S000006229
GO:0005634	nucleus	C	IDA Ath At5g27620 Mmu MGI:1913921 Spo SPBP16F5.02
GO:0005675	holo TFIIH complex	C	IDA Sce S000006229 ISS Dme FBgn0022936 Spo SPBP16F5.02
GO:0005737	cytoplasm	C	IDA Ath At5g27620
GO:0005739	mitochondrion	C	IDA Sce S000006229
GO:0070985	TFIIK complex	C	IDA Sce S000006229
GO:0004672	protein kinase activity	F	IDA Ath At5g27620
GO:0004693	cyclin-dependent protein kinase activity	F	ISS Ath At5g27620 Mmu MGI:1913921
GO:0004861	cyclin-dependent protein kinase inhibitor activity	F	IGI Spo SPBP16F5.02
GO:0005515	protein binding	F	IPI Ath At5g27620 Spo SPBP16F5.02
GO:0016251	general RNA polymerase II transcription factor activity	F	IDA Sce S000006229 ISS Dme FBgn0022936
GO:0016301	kinase activity	F	IDA Mmu MGI:1913921
GO:0016538	cyclin-dependent protein kinase regulator activity	F	ISS Dme FBgn0022936
GO:0000003	reproduction	P	IMP Cel WBGene00021714
GO:0000079	regulation of cyclin-dependent protein kinase activity	P	NAS Spo SPBP16F5.02
GO:0002009	morphogenesis of an epithelium	P	IMP Cel WBGene00021714
GO:0002119	nematode larval development	P	IMP Cel WBGene00021714
GO:0006367	transcription initiation from RNA polymerase II promoter	P	ISS Dme FBgn0022936 Spo SPBP16F5.02
GO:0007049	cell cycle	P	ISS Mmu MGI:1913921
GO:0007346	regulation of mitotic cell cycle	P	IGI Spo SPBP16F5.02
GO:0009792	embryo development ending in birth or egg hatching	P	IMP Cel WBGene00021714
GO:0010171	body morphogenesis	P	IMP Cel WBGene00021714
GO:0016310	phosphorylation	P	IDA Mmu MGI:1913921 ISS Mmu MGI:1913921
GO:0032568	general transcription from RNA polymerase II promoter	P	IDA Sce S000006229
GO:0040007	growth	P	IMP Cel WBGene00021714
GO:0040010	positive regulation of growth rate	P	IMP Cel WBGene00021714
GO:0040011	locomotion	P	IMP Cel WBGene00021714
GO:0040035	hermaphrodite genitalia development	P	IMP Cel WBGene00021714
GO:0042326	negative regulation of phosphorylation	P	IGI Spo SPBP16F5.02
GO:0051726	regulation of cell cycle	P	ISS Ath At5g27620
GO:0070816	phosphorylation of RNA polymerase II C-terminal domain	P	IDA Sce S000006229

Curated yeast ortholog results:

S. pombe systematic ID	S. cerevisiae systematic ID
SPBP16F5.02 (P36613)	YPR025C (S000006229)

GO terms for curated homolog results:

GO ID	GO term	GO aspect	Evidence codes and associations
GO:0000109	nucleotide-excision repair complex	C	RCA Sce S000006229
GO:0005634	nucleus	C	IDA Spo SPBP16F5.02
GO:0005675	holo TFIIH complex	C	IDA Sce S000006229 ISS Spo SPBP16F5.02
GO:0005739	mitochondrion	C	IDA Sce S000006229
GO:0070985	TFIIK complex	C	IDA Sce S000006229
GO:0004861	cyclin-dependent protein kinase inhibitor activity	F	IGI Spo SPBP16F5.02
GO:0005515	protein binding	F	IPI Spo SPBP16F5.02
GO:0016251	general RNA polymerase II transcription factor activity	F	IDA Sce S000006229
GO:0000079	regulation of cyclin-dependent protein kinase activity	P	NAS Spo SPBP16F5.02
GO:0006367	transcription initiation from RNA polymerase II promoter	P	ISS Spo SPBP16F5.02
GO:0007346	regulation of mitotic cell cycle	P	IGI Spo SPBP16F5.02
GO:0032568	general transcription from RNA polymerase II promoter	P	IDA Sce S000006229
GO:0042326	negative regulation of phosphorylation	P	IGI Spo SPBP16F5.02
GO:0070816	phosphorylation of RNA polymerase II C-terminal domain	P	IDA Sce S000006229