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Search term: YPR041W

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name TIF5
SGD link S000006245
Alternative ID YPR041W
Description Translation initiation factor eIF-5; N-terminal domain functions as a GTPase-activating protein to mediate hydrolysis of ribosome-bound GTP; C-terminal domain is the core of ribosomal preinitiation complex formation
Synonyms YPR041W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG2767 ACDHYPE

KOGs classification KOGs description
INFORMATION STORAGE AND PROCESSING Translation initiation factor 5 (eIF-5)

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At1g36730 GI:15221135
Arabidopsis thaliana (Ath) At1g77840 GI:15218142
Caenorhabditis elegans (Cel) CE27367
(WBGene00016496)		 GI:17558470
Drosophila melanogaster (Dme) 7293169
(FBgn0030719)		 GI:18860089
Homo sapiens (Hsa) Hs21361337 GI:10439908 P55010
Homo sapiens (Hsa) HsM4503543 GI:4503543
Saccharomyces cerevisiae (Sce) YPR041w
(S000006245)		 GI:6325298 P38431
Schizosaccharomyces pombe (Spo) SPAC2F7.05c GI:19113888 Q09689
Encephalitozoon cuniculi (Ecu) ECU07g1330 GI:19074556 Q8SRI1


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
AthAt1g77840
GO:0005737 cytoplasm C
IDA
AthAt1g77840
GO:0005829 cytosol C
IDA
SpoSPAC2F7.05c
ISS
DmeFBgn0030719
GO:0005850 eukaryotic translation initiation factor 2
complex		 C
RCA
SceS000006245
GO:0022627 cytosolic small ribosomal subunit C
IPI
SceS000006245
ISS
SpoSPAC2F7.05c
GO:0043614 multi-eIF complex C
IDA
SceS000006245
GO:0003743 translation initiation factor activity F
ISS
AthAt1g77840
At1g36730
DmeFBgn0030719
SceS000006245
SpoSPAC2F7.05c
GO:0005096 GTPase activator activity F
IPI
SceS000006245
ISS
SceS000006245
SpoSPAC2F7.05c
GO:0000003 reproduction P
IMP
CelWBGene00016496
GO:0002119 nematode larval development P
IMP
CelWBGene00016496
GO:0006413 translational initiation P
ISS
DmeFBgn0030719
SpoSPAC2F7.05c
RCA
SceS000006245
GO:0006417 regulation of translation P
RCA
SceS000006245
GO:0006446 regulation of translational initiation P
IMP
SceS000006245
IPI
SceS000006245
ISS
AthAt1g36730
At1g77840
GO:0006898 receptor-mediated endocytosis P
IMP
CelWBGene00016496
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00016496
GO:0018996 molting cycle, collagen and cuticulin-based
cuticle		 P
IMP
CelWBGene00016496
GO:0040007 growth P
IMP
CelWBGene00016496
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00016496
GO:0042256 mature ribosome assembly P
IMP
SceS000006245
ISS
SpoSPAC2F7.05c
GO:0045948 positive regulation of translational
initiation		 P
ISS
SpoSPAC2F7.05c

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
49610

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) EIF5 GI:21361337
Pan troglodytes (Ptr) EIF5 GI:114654952
Canis familiaris (Cfa) EIF5 GI:73964077
Mus musculus (Mmu) Eif5
(MGI:95309)		 GI:124430541 P59325
Rattus norvegicus (Rno) Eif5
(RGD:619861)		 GI:9910214
Gallus gallus (Gga) EIF5 GI:57529904
Drosophila melanogaster (Dme) eIF5
(FBgn0030719)		 GI:18860089
Anopheles gambiae (Aga) AgaP_AGAP011203 GI:58377148
Caenorhabditis elegans (Cel) C37C3.2
(CE27367;
WBGene00016496)		 GI:25146151
Schizosaccharomyces pombe (Spo) SPAC2F7.05c GI:19113888 Q09689
Saccharomyces cerevisiae (Sce) TIF5
(S000006245)		 GI:6325298 P38431
Kluyveromyces lactis (Kla) KLLA0E06050g GI:50308439
Eremothecium gossypii (Ego) AGOS_AER400C GI:45191001
Magnaporthe grisea (Mgr) MGG_08866 GI:39953837
Neurospora crassa (Ncr) NCU00366.1 GI:32403678
Arabidopsis thaliana (Ath) AT1G36730 GI:15221135
Oryza sativa (Osa) Os09g0326900 GI:115478583
Plasmodium falciparum (Pfa) PFL0335c GI:124805565


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
PfaPFL0335c
GO:0005737 cytoplasm C
TAS
HsaEIF5
GO:0005829 cytosol C
IDA
SpoSPAC2F7.05c
ISS
DmeFBgn0030719
NAS
HsaEIF5
GO:0005850 eukaryotic translation initiation factor 2
complex		 C
RCA
SceS000006245
GO:0022627 cytosolic small ribosomal subunit C
IPI
SceS000006245
ISS
SpoSPAC2F7.05c
GO:0043614 multi-eIF complex C
IDA
SceS000006245
GO:0003743 translation initiation factor activity F
ISO
MmuMGI:95309
ISS
AthAt1g36730
DmeFBgn0030719
SceS000006245
SpoSPAC2F7.05c
NAS
HsaEIF5
GO:0003924 GTPase activity F
TAS
HsaEIF5
GO:0005096 GTPase activator activity F
IPI
SceS000006245
ISS
SceS000006245
SpoSPAC2F7.05c
GO:0008135 translation factor activity, nucleic acid
binding		 F
TAS
HsaEIF5
GO:0000003 reproduction P
IMP
CelWBGene00016496
GO:0002119 nematode larval development P
IMP
CelWBGene00016496
GO:0006413 translational initiation P
ISS
DmeFBgn0030719
SpoSPAC2F7.05c
NAS
HsaEIF5
RCA
SceS000006245
GO:0006417 regulation of translation P
RCA
SceS000006245
GO:0006446 regulation of translational initiation P
IMP
SceS000006245
IPI
SceS000006245
ISS
AthAt1g36730
PfaPFL0335c
TAS
HsaEIF5
GO:0006898 receptor-mediated endocytosis P
IMP
CelWBGene00016496
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00016496
GO:0018996 molting cycle, collagen and cuticulin-based
cuticle		 P
IMP
CelWBGene00016496
GO:0040007 growth P
IMP
CelWBGene00016496
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00016496
GO:0042256 mature ribosome assembly P
IMP
SceS000006245
ISS
SpoSPAC2F7.05c
GO:0045948 positive regulation of translational
initiation		 P
ISS
SpoSPAC2F7.05c

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_792

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga8251 ENSANGP00000011246
Anopheles gambiae (Aga) aga8252 ENSANGP00000026610
Ashbya gossypii (Ago) ago2900 AER400C
Arabidopsis thaliana (Ath) ath3732 At1g36730.1
Arabidopsis thaliana (Ath) ath7127 At1g77840.1
Caenorhabditis elegans (Cel) cel3638 C37C3.2a
(CE27367;
WBGene00016496)
Caenorhabditis elegans (Cel) cel3639 C37C3.2b
(CE29707)
Caenorhabditis elegans (Cel) cel3640 C37C3.2c
(CE32821)
Candida glabrata (Cgl) cgl822 CAGL0D03718g
Cryptococcus neoformans (Cne) cne5349 179.m00201
Dictyostelium discoideum (Ddi) ddi7886 DDB0187131
Debaryomyces hansenii (Dha) dha6847 DEHA0G25839g
Drosophila melanogaster (Dme) dme18091 CG9177-PA
(FBgn0030719)
Drosophila melanogaster (Dme) dme18092 CG9177-PB
(FBgn0030719)
Drosophila melanogaster (Dme) dme18093 CG9177-PC
(FBgn0030719)
Drosophila melanogaster (Dme) dme18094 CG9177-PD
(FBgn0030719)
Drosophila melanogaster (Dme) dme18095 CG9177-PE
(FBgn0030719)
Drosophila melanogaster (Dme) dme18096 CG9177-PF
(FBgn0030719)
Drosophila melanogaster (Dme) dme18097 CG9177-PG
(FBgn0030719)
Danio rerio (Dre) dre12248 ENSDARP00000020566
(eif5)		 Q7ZWA9
Encephalitozoon cuniculi (Ecu) ecu1942 19074556
Takifugu rubripes (Fru) fru4520 SINFRUP00000159337
Takifugu rubripes (Fru) fru4519 SINFRUP00000176621
Gallus gallus (Gga) gga19843 ENSGALP00000018668
Gallus gallus (Gga) gga19842 ENSGALP00000018669
(EIF5)		 Q5ZIE0
Homo sapiens (Hsa) hsa10152 ENSP00000216554
(EIF5)		 P55010
Homo sapiens (Hsa) hsa10153 ENSP00000340365
Kluyveromyces lactis (Kla) kla3220 KLLA0E06050g
Mus musculus (Mmu) mmu6298 ENSMUSP00000061616
(MGI:95309)		 P59325
Mus musculus (Mmu) mmu16641 ENSMUSP00000073485
Mus musculus (Mmu) mmu6297 ENSMUSP00000074018
(MGI:95309)		 Q8BVV6
Neurospora crassa (Ncr) ncr352 NCU00366.2
Oryza sativa (Osa) osa53972 6149.m00345
Plasmodium falciparum (Pfa) pfa4853 PFL0335c
Rattus norvegicus (Rno) rno26743 ENSRNOP00000008623
Rattus norvegicus (Rno) rno25690 ENSRNOP00000013695
(RGD:619861)		 Q07205
Rattus norvegicus (Rno) rno25689 ENSRNOP00000032099
(RGD:619861)
Rattus norvegicus (Rno) rno18718 ENSRNOP00000034624
Rattus norvegicus (Rno) rno25691 ENSRNOP00000037209
(RGD:619861)
Rattus norvegicus (Rno) rno30761 ENSRNOP00000045192
Saccharomyces cerevisiae (Sce) sce6496 YPR041W
(S000006245)
Schizosaccharomyces pombe (Spo) spo4377 SPAC2F7.05c Q09689
Yarrowia lipolytica (Yli) yli3015 YALI0D07436g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
PfaPFL0335c
GO:0005634 nucleus C
IDA
AthAt1g77840
GO:0005737 cytoplasm C
IDA
AthAt1g77840
GO:0005829 cytosol C
IDA
SpoSPAC2F7.05c
ISS
DmeFBgn0030719
GO:0005850 eukaryotic translation initiation factor 2
complex		 C
RCA
SceS000006245
GO:0022627 cytosolic small ribosomal subunit C
IPI
SceS000006245
ISS
SpoSPAC2F7.05c
GO:0043614 multi-eIF complex C
IDA
SceS000006245
GO:0003743 translation initiation factor activity F
ISO
MmuMGI:95309
ISS
AthAt1g77840
At1g36730
DmeFBgn0030719
SceS000006245
SpoSPAC2F7.05c
GO:0005096 GTPase activator activity F
IPI
SceS000006245
ISS
SceS000006245
SpoSPAC2F7.05c
GO:0000003 reproduction P
IMP
CelWBGene00016496
GO:0002119 nematode larval development P
IMP
CelWBGene00016496
GO:0006413 translational initiation P
ISS
DmeFBgn0030719
SpoSPAC2F7.05c
RCA
SceS000006245
GO:0006417 regulation of translation P
RCA
SceS000006245
GO:0006446 regulation of translational initiation P
IMP
SceS000006245
IPI
SceS000006245
ISS
AthAt1g36730
At1g77840
PfaPFL0335c
GO:0006898 receptor-mediated endocytosis P
IMP
CelWBGene00016496
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00016496
GO:0018996 molting cycle, collagen and cuticulin-based
cuticle		 P
IMP
CelWBGene00016496
GO:0040007 growth P
IMP
CelWBGene00016496
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00016496
GO:0042256 mature ribosome assembly P
IMP
SceS000006245
ISS
SpoSPAC2F7.05c
GO:0045948 positive regulation of translational
initiation		 P
ISS
SpoSPAC2F7.05c

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPAC2F7.05c
(Q09689)		 YPR041W
(S000006245)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005829 cytosol C
IDA
SpoSPAC2F7.05c
GO:0005850 eukaryotic translation initiation factor 2
complex		 C
RCA
SceS000006245
GO:0022627 cytosolic small ribosomal subunit C
IPI
SceS000006245
ISS
SpoSPAC2F7.05c
GO:0043614 multi-eIF complex C
IDA
SceS000006245
GO:0003743 translation initiation factor activity F
ISS
SceS000006245
SpoSPAC2F7.05c
GO:0005096 GTPase activator activity F
IPI
SceS000006245
ISS
SceS000006245
SpoSPAC2F7.05c
GO:0006413 translational initiation P
ISS
SpoSPAC2F7.05c
RCA
SceS000006245
GO:0006417 regulation of translation P
RCA
SceS000006245
GO:0006446 regulation of translational initiation P
IMP
SceS000006245
IPI
SceS000006245
GO:0042256 mature ribosome assembly P
IMP
SceS000006245
ISS
SpoSPAC2F7.05c
GO:0045948 positive regulation of translational
initiation		 P
ISS
SpoSPAC2F7.05c

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