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Search term: YPR048W


Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name TAH18
SGD link S000006252
Alternative ID YPR048W
Description Protein of unknown function that plays a pro-death role in response to oxidative stress; highly conserved across species and similar to human protein NDOR1; allele is synthetically lethal with the pol3-13 allele of DNA polymerase delta
Synonyms YPR048W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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Query species:

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GO info in one table:


KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG1159 ACDHYPE

KOGs classification KOGs description
METABOLISM NADP-dependent flavoprotein reductase

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At3g02280 GI:15232878
Arabidopsis thaliana (Ath) At3g24710_1 GI:15230163
Caenorhabditis elegans (Cel) CE23279
(WBGene00001485)
GI:17566446 Q9U2Y8
Drosophila melanogaster (Dme) 7295098 GI:7295098
Homo sapiens (Hsa) Hs7657393 GI:7657393 Q9UHB4
Saccharomyces cerevisiae (Sce) YPR048w
(S000006252)
GI:6325305 Q12181
Schizosaccharomyces pombe (Spo) SPAC1296.06 GI:19113958 O94613
Encephalitozoon cuniculi (Ecu) ECU05g0240 GI:19173560 Q8SS06
Arabidopsis thaliana (Ath) At3g02280 GI:15232878
Arabidopsis thaliana (Ath) At3g24710_1 GI:15230163
Caenorhabditis elegans (Cel) CE23279
(WBGene00001485)
GI:17566446 Q9U2Y8
Drosophila melanogaster (Dme) 7295098 GI:7295098
Homo sapiens (Hsa) Hs7657393 GI:7657393 Q9UHB4
Saccharomyces cerevisiae (Sce) YPR048w
(S000006252)
GI:6325305 Q12181
Schizosaccharomyces pombe (Spo) SPAC1296.06 GI:19113958 O94613
Encephalitozoon cuniculi (Ecu) ECU05g0240 GI:19173560 Q8SS06


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
AthAt3g02280
SpoSPAC1296.06
GO:0005634 nucleus C
IDA
CelWBGene00001485
GO:0005739 mitochondrion C
IDA
SceS000006252
GO:0003674 molecular_function F
ND
AthAt3g24710
GO:0010181 FMN binding F
ISS
SpoSPAC1296.06
GO:0016491 oxidoreductase activity F
ISS
AthAt3g02280
SpoSPAC1296.06
GO:0016651 oxidoreductase activity, acting on NADH or
NADPH
F
IDA
SceS000006252
GO:0050660 FAD binding F
ISS
SpoSPAC1296.06
GO:0050661 NADP or NADPH binding F
ISS
SpoSPAC1296.06
GO:0008150 biological_process P
ND
AthAt3g24710
At3g02280
SpoSPAC1296.06
GO:0009408 response to heat P
IEP
CelWBGene00001485
GO:0016226 iron-sulfur cluster assembly P
IMP
SceS000006252
GO:0031329 regulation of cellular catabolic
process
P
RCA
SceS000006252
GO:0055114 oxidation reduction P
IDA
SceS000006252

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
7144

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) NDOR1 GI:221316705
Pan troglodytes (Ptr) NDOR1 GI:114627709
Canis familiaris (Cfa) NDOR1 GI:73967454
Mus musculus (Mmu) Ndor1
(MGI:1926047)
GI:126723293 A2AI05
Rattus norvegicus (Rno) Ndor1 GI:109467848
Gallus gallus (Gga) NDOR1 GI:118099142
Drosophila melanogaster (Dme) CG13667
(FBgn0035890)
GI:24660907
Anopheles gambiae (Aga) AgaP_AGAP003889 GI:118777517
Caenorhabditis elegans (Cel) fre-1
(CE23279;
WBGene00001485)
GI:17566446 Q9U2Y8
Schizosaccharomyces pombe (Spo) SPAC1296.06 GI:19113958 O94613
Saccharomyces cerevisiae (Sce) TAH18
(S000006252)
GI:6325305 Q12181
Kluyveromyces lactis (Kla) KLLA0B12155g GI:50304243
Eremothecium gossypii (Ego) AGOS_ADL306C GI:45187567
Arabidopsis thaliana (Ath) AT3G02280 GI:30678524
Oryza sativa (Osa) Os01g0733600 GI:115439765


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
AthAt3g02280
MmuMGI:1926047
SpoSPAC1296.06
GO:0005634 nucleus C
IDA
CelWBGene00001485
GO:0005737 cytoplasm C
IDA
HsaNDOR1
GO:0005739 mitochondrion C
IDA
SceS000006252
GO:0005829 cytosol C
IDA
HsaNDOR1
GO:0003674 molecular_function F
ND
MmuMGI:1926047
GO:0005515 protein binding F
IPI
HsaNDOR1
GO:0010181 FMN binding F
IDA
HsaNDOR1
ISS
SpoSPAC1296.06
GO:0016491 oxidoreductase activity F
IDA
HsaNDOR1
ISS
AthAt3g02280
DmeFBgn0035890
SpoSPAC1296.06
GO:0016651 oxidoreductase activity, acting on NADH or
NADPH
F
IDA
SceS000006252
GO:0050660 FAD binding F
IDA
HsaNDOR1
ISS
SpoSPAC1296.06
GO:0050661 NADP or NADPH binding F
IDA
HsaNDOR1
ISS
SpoSPAC1296.06
GO:0008150 biological_process P
ND
AthAt3g02280
MmuMGI:1926047
SpoSPAC1296.06
GO:0008219 cell death P
IDA
HsaNDOR1
GO:0009408 response to heat P
IEP
CelWBGene00001485
GO:0016226 iron-sulfur cluster assembly P
IMP
SceS000006252
GO:0031329 regulation of cellular catabolic
process
P
RCA
SceS000006252
GO:0055114 oxidation reduction P
IDA
HsaNDOR1
SceS000006252

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_2253

Species OrthoMCL
sequence
Model organism
protein page
UniProt link
Anopheles gambiae (Aga) aga6394 ENSANGP00000003321
Ashbya gossypii (Ago) ago1435 ADL306C
Arabidopsis thaliana (Ath) ath12241 At3g02280.1
Caenorhabditis elegans (Cel) cel17678 Y113G7A.8
(CE23279;
WBGene00001485)
Candida glabrata (Cgl) cgl2440 CAGL0H08580g
Cryptococcus neoformans (Cne) cne1514 180.m00470
Dictyostelium discoideum (Ddi) ddi7281 DDB0187719
Debaryomyces hansenii (Dha) dha3196 DEHA0D20097g
Drosophila melanogaster (Dme) dme8563 CG13667-PA
(FBgn0035890)
Drosophila melanogaster (Dme) dme8564 CG13667-PB
(FBgn0035890)
Danio rerio (Dre) dre25110 ENSDARP00000031709
(LOC561728)
Encephalitozoon cuniculi (Ecu) ecu1122 19173560
Takifugu rubripes (Fru) fru22400 SINFRUP00000135364
Takifugu rubripes (Fru) fru22401 SINFRUP00000167530
Gallus gallus (Gga) gga8214 ENSGALP00000014485
(NDOR1)
Homo sapiens (Hsa) hsa32290 ENSP00000343344
(NDOR1)
Q9UHB4-1
Kluyveromyces lactis (Kla) kla1069 KLLA0B12155g
Mus musculus (Mmu) mmu14196 ENSMUSP00000006640
(MGI:1926047)
A2AI05-3
Neurospora crassa (Ncr) ncr9471 NCU09727.2
Oryza sativa (Osa) osa11976 2809.m00158
Oryza sativa (Osa) osa31458 4409.m00120
Plasmodium falciparum (Pfa) pfa1158 PF14_0478
Rattus norvegicus (Rno) rno18136 ENSRNOP00000014445
(RGD:1308479)
Saccharomyces cerevisiae (Sce) sce6503 YPR048W
(S000006252)
Schizosaccharomyces pombe (Spo) spo3086 SPAC1296.06 O94613
Yarrowia lipolytica (Yli) yli2107 YALI0C09460g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
AthAt3g02280
MmuMGI:1926047
SpoSPAC1296.06
GO:0005634 nucleus C
IDA
CelWBGene00001485
GO:0005739 mitochondrion C
IDA
SceS000006252
GO:0003674 molecular_function F
ND
MmuMGI:1926047
GO:0010181 FMN binding F
ISS
SpoSPAC1296.06
GO:0016491 oxidoreductase activity F
ISS
AthAt3g02280
DmeFBgn0035890
SpoSPAC1296.06
GO:0016651 oxidoreductase activity, acting on NADH or
NADPH
F
IDA
SceS000006252
GO:0050660 FAD binding F
ISS
SpoSPAC1296.06
GO:0050661 NADP or NADPH binding F
ISS
SpoSPAC1296.06
GO:0008150 biological_process P
ND
AthAt3g02280
MmuMGI:1926047
SpoSPAC1296.06
GO:0009408 response to heat P
IEP
CelWBGene00001485
GO:0016226 iron-sulfur cluster assembly P
IMP
SceS000006252
GO:0031329 regulation of cellular catabolic
process
P
RCA
SceS000006252
GO:0055114 oxidation reduction P
IDA
SceS000006252

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Curated yeast ortholog results:

S. pombe
systematic ID
S. cerevisiae
systematic ID
SPAC1296.06
(O94613)
YPR048W
(S000006252)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
SpoSPAC1296.06
GO:0005739 mitochondrion C
IDA
SceS000006252
GO:0010181 FMN binding F
ISS
SpoSPAC1296.06
GO:0016491 oxidoreductase activity F
ISS
SpoSPAC1296.06
GO:0016651 oxidoreductase activity, acting on NADH or
NADPH
F
IDA
SceS000006252
GO:0050660 FAD binding F
ISS
SpoSPAC1296.06
GO:0050661 NADP or NADPH binding F
ISS
SpoSPAC1296.06
GO:0008150 biological_process P
ND
SpoSPAC1296.06
GO:0016226 iron-sulfur cluster assembly P
IMP
SceS000006252
GO:0031329 regulation of cellular catabolic
process
P
RCA
SceS000006252
GO:0055114 oxidation reduction P
IDA
SceS000006252

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GO info in one table:

s.khadayate@ucl.ac.uk