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Search term: YPR056W

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name TFB4
SGD link S000006260
Alternative ID YPR056W
Description Subunit of TFIIH complex, involved in transcription initiation, similar to 34 kDa subunit of human TFIIH; interacts with Ssl1p
Synonyms YPR056W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG2487 ACDHYPE

KOGs classification KOGs description
INFORMATION STORAGE AND PROCESSINGINFORMATION STORAGE AND PROCESSING RNA polymerase II transcription initiation/nucleotide excision repair factor TFIIH, subunit TFB4

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At1g18340_1 GI:15221059
Caenorhabditis elegans (Cel) CE01686
(WBGene00014230)		 GI:17557141
Drosophila melanogaster (Dme) 7296117 GI:7296117
Homo sapiens (Hsa) Hs19923732
(GTF2H3)		 GI:19923732 Q8NEI1
Saccharomyces cerevisiae (Sce) YPR056w
(S000006260)		 GI:6325313 Q12004
Schizosaccharomyces pombe (Spo) SPBC30B4.07c GI:19112324 O74366
Encephalitozoon cuniculi (Ecu) ECU07g0880 GI:19074510 Q8SV04


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000112 nucleotide-excision repair factor 3
complex		 C
IPI
SceS000006260
GO:0000439 core TFIIH complex C
IDA
SceS000006260
GO:0005634 nucleus C
IDA
SpoSPBC30B4.07c
GO:0005654 nucleoplasm C
EXP
HsaGTF2H3
GO:0005675 holo TFIIH complex C
IDA
HsaGTF2H3
SceS000006260
ISS
SpoSPBC30B4.07c
NAS
HsaGTF2H3
GO:0005829 cytosol C
IDA
SpoSPBC30B4.07c
GO:0003684 damaged DNA binding F
NAS
HsaGTF2H3
GO:0003700 transcription factor activity F
NAS
HsaGTF2H3
GO:0004672 protein kinase activity F
IDA
HsaGTF2H3
GO:0008094 DNA-dependent ATPase activity F
IDA
HsaGTF2H3
GO:0008135 translation factor activity, nucleic acid
binding		 F
TAS
HsaGTF2H3
GO:0008353 RNA polymerase II carboxy-terminal domain kinase
activity		 F
IDA
HsaGTF2H3
GO:0016251 general RNA polymerase II transcription factor
activity		 F
IDA
SceS000006260
ISS
SpoSPBC30B4.07c
GO:0047485 protein N-terminus binding F
IPI
HsaGTF2H3
GO:0000003 reproduction P
IMP
CelWBGene00014230
GO:0000718 nucleotide-excision repair, DNA damage
removal		 P
EXP
HsaGTF2H3
GO:0006281 DNA repair P
TAS
HsaGTF2H3
GO:0006289 nucleotide-excision repair P
IMP
SceS000006260
ISS
SpoSPBC30B4.07c
NAS
HsaGTF2H3
GO:0006355 regulation of transcription, DNA-dependent P
NAS
HsaGTF2H3
GO:0006366 transcription from RNA polymerase II
promoter		 P
IDA
HsaGTF2H3
GO:0006367 transcription initiation from RNA polymerase II
promoter		 P
EXP
HsaGTF2H3
ISS
SpoSPBC30B4.07c
GO:0006368 RNA elongation from RNA polymerase II
promoter		 P
EXP
HsaGTF2H3
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00014230
GO:0032568 general transcription from RNA polymerase II
promoter		 P
IDA
SceS000006260
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00014230
GO:0070816 phosphorylation of RNA polymerase II C-terminal
domain		 P
IDA
SceS000006260

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
1160

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) GTF2H3 GI:19923732 Q8NEI1
Pan troglodytes (Ptr) GTF2H3 GI:114647703
Canis familiaris (Cfa) GTF2H3 GI:57105536
Mus musculus (Mmu) Gtf2h3
(MGI:1277143)		 GI:31088894 Q3UZB8
Rattus norvegicus (Rno) Gtf2h3
(RGD:1305494)		 GI:66730451
Gallus gallus (Gga) GTF2H3 GI:118098479
Drosophila melanogaster (Dme) Tfb4
(FBgn0031309)		 GI:24580793
Anopheles gambiae (Aga) AgaP_AGAP008522 GI:158296528
Schizosaccharomyces pombe (Spo) tfb4
(SPBC30B4.07c)		 GI:19112324 O74366
Saccharomyces cerevisiae (Sce) TFB4
(S000006260)		 GI:6325313 Q12004
Kluyveromyces lactis (Kla) KLLA0B08569g GI:50303925
Eremothecium gossypii (Ego) AGOS_ADL323C GI:45187550
Magnaporthe grisea (Mgr) MGG_03877 GI:39943732
Neurospora crassa (Ncr) NCU01580.1 GI:32415079
Arabidopsis thaliana (Ath) AT1G18340 GI:18394597
Oryza sativa (Osa) Os02g0125800 GI:115443937


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000112 nucleotide-excision repair factor 3
complex		 C
IPI
SceS000006260
GO:0000439 core TFIIH complex C
IDA
SceS000006260
GO:0005575 cellular_component C
ND
MmuMGI:1277143
GO:0005634 nucleus C
IDA
SpoSPBC30B4.07c
GO:0005654 nucleoplasm C
EXP
HsaGTF2H3
GO:0005675 holo TFIIH complex C
IDA
HsaGTF2H3
SceS000006260
ISS
DmeFBgn0031309
SpoSPBC30B4.07c
NAS
HsaGTF2H3
GO:0005829 cytosol C
IDA
SpoSPBC30B4.07c
GO:0003674 molecular_function F
ND
MmuMGI:1277143
GO:0003684 damaged DNA binding F
NAS
HsaGTF2H3
GO:0003700 transcription factor activity F
NAS
HsaGTF2H3
GO:0004672 protein kinase activity F
IDA
HsaGTF2H3
GO:0008094 DNA-dependent ATPase activity F
IDA
HsaGTF2H3
GO:0008135 translation factor activity, nucleic acid
binding		 F
TAS
HsaGTF2H3
GO:0008353 RNA polymerase II carboxy-terminal domain kinase
activity		 F
IDA
HsaGTF2H3
GO:0016251 general RNA polymerase II transcription factor
activity		 F
IDA
SceS000006260
ISS
DmeFBgn0031309
SpoSPBC30B4.07c
GO:0047485 protein N-terminus binding F
IPI
HsaGTF2H3
GO:0000718 nucleotide-excision repair, DNA damage
removal		 P
EXP
HsaGTF2H3
GO:0006281 DNA repair P
TAS
HsaGTF2H3
GO:0006289 nucleotide-excision repair P
IMP
SceS000006260
ISS
SpoSPBC30B4.07c
NAS
HsaGTF2H3
GO:0006355 regulation of transcription, DNA-dependent P
NAS
HsaGTF2H3
GO:0006366 transcription from RNA polymerase II
promoter		 P
IDA
HsaGTF2H3
GO:0006367 transcription initiation from RNA polymerase II
promoter		 P
EXP
HsaGTF2H3
ISS
DmeFBgn0031309
SpoSPBC30B4.07c
GO:0006368 RNA elongation from RNA polymerase II
promoter		 P
EXP
HsaGTF2H3
GO:0008150 biological_process P
ND
MmuMGI:1277143
GO:0032568 general transcription from RNA polymerase II
promoter		 P
IDA
SceS000006260
GO:0070816 phosphorylation of RNA polymerase II C-terminal
domain		 P
IDA
SceS000006260

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_2316

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga10526 ENSANGP00000011127
Ashbya gossypii (Ago) ago1418 ADL323C
Arabidopsis thaliana (Ath) ath1966 At1g18340.1
Caenorhabditis elegans (Cel) cel21582 ZK1128.4
(CE01686;
WBGene00014230)
Candida glabrata (Cgl) cgl732 CAGL0D01650g
Cryptococcus neoformans (Cne) cne1690 164.m02033
Dictyostelium discoideum (Ddi) ddi12096 DDB0230196
Debaryomyces hansenii (Dha) dha5134 DEHA0F16786g
Drosophila melanogaster (Dme) dme199 CG5041-PA
(FBgn0031309)
Danio rerio (Dre) dre3293 ENSDARP00000042073
Encephalitozoon cuniculi (Ecu) ecu1896 19074510
Takifugu rubripes (Fru) fru2483 SINFRUP00000127843
Gallus gallus (Gga) gga7157 ENSGALP00000005121
Homo sapiens (Hsa) hsa8419 ENSP00000228955
(GTF2H3)		 Q13889
Kluyveromyces lactis (Kla) kla908 KLLA0B08569g
Mus musculus (Mmu) mmu20955 ENSMUSP00000031333
(MGI:1277143)		 Q8VD76
Neurospora crassa (Ncr) ncr1535 NCU01580.2
Oryza sativa (Osa) osa38291 4889.m00149
Oryza sativa (Osa) osa38498 4896.m00177
Oryza sativa (Osa) osa38546 4896.m00240
Oryza sativa (Osa) osa38547 4896.m00241
Plasmodium falciparum (Pfa) pfa3796 PF13_0279
Rattus norvegicus (Rno) rno8516 ENSRNOP00000001368
(RGD:1305494)		 Q561R7
Saccharomyces cerevisiae (Sce) sce6511 YPR056W
(S000006260)
Schizosaccharomyces pombe (Spo) spo255 SPBC30B4.07c O74366
Yarrowia lipolytica (Yli) yli1897 YALI0C04367g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000112 nucleotide-excision repair factor 3
complex		 C
IPI
SceS000006260
GO:0000439 core TFIIH complex C
IDA
SceS000006260
GO:0005575 cellular_component C
ND
MmuMGI:1277143
GO:0005634 nucleus C
IDA
SpoSPBC30B4.07c
GO:0005675 holo TFIIH complex C
IDA
SceS000006260
ISS
DmeFBgn0031309
SpoSPBC30B4.07c
GO:0005829 cytosol C
IDA
SpoSPBC30B4.07c
GO:0003674 molecular_function F
ND
MmuMGI:1277143
GO:0016251 general RNA polymerase II transcription factor
activity		 F
IDA
SceS000006260
ISS
DmeFBgn0031309
SpoSPBC30B4.07c
GO:0000003 reproduction P
IMP
CelWBGene00014230
GO:0006289 nucleotide-excision repair P
IMP
SceS000006260
ISS
SpoSPBC30B4.07c
GO:0006367 transcription initiation from RNA polymerase II
promoter		 P
ISS
DmeFBgn0031309
SpoSPBC30B4.07c
GO:0008150 biological_process P
ND
MmuMGI:1277143
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00014230
GO:0032568 general transcription from RNA polymerase II
promoter		 P
IDA
SceS000006260
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00014230
GO:0070816 phosphorylation of RNA polymerase II C-terminal
domain		 P
IDA
SceS000006260

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPBC30B4.07c
(O74366)		 YPR056W
(S000006260)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000112 nucleotide-excision repair factor 3
complex		 C
IPI
SceS000006260
GO:0000439 core TFIIH complex C
IDA
SceS000006260
GO:0005634 nucleus C
IDA
SpoSPBC30B4.07c
GO:0005675 holo TFIIH complex C
IDA
SceS000006260
ISS
SpoSPBC30B4.07c
GO:0005829 cytosol C
IDA
SpoSPBC30B4.07c
GO:0016251 general RNA polymerase II transcription factor
activity		 F
IDA
SceS000006260
ISS
SpoSPBC30B4.07c
GO:0006289 nucleotide-excision repair P
IMP
SceS000006260
ISS
SpoSPBC30B4.07c
GO:0006367 transcription initiation from RNA polymerase II
promoter		 P
ISS
SpoSPBC30B4.07c
GO:0032568 general transcription from RNA polymerase II
promoter		 P
IDA
SceS000006260
GO:0070816 phosphorylation of RNA polymerase II C-terminal
domain		 P
IDA
SceS000006260

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Search for gene by ID or name:

Query species:

Include wild-cards:   

Search for GO info:  

GO info in one table:

s.khadayate@ucl.ac.uk